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Differential nuclear import sets the timing of protein access to the embryonic genome. , Nguyen T, Costa EJ, Deibert T, Reyes J, Keber FC, Tomschik M , Stadlmeier M, Gupta M, Kumar CK, Cruz ER, Amodeo A , Gatlin JC , Wühr M ., Nat Commun. October 6, 2022; 13 (1): 5887.
Inhibition of DNA replication initiation by silver nanoclusters. , Tao Y, Aparicio T , Li M, Leong KW, Zha S, Gautier J ., Nucleic Acids Res. May 21, 2021; 49 (9): 5074-5083.
SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development. , Falbo L, Raspelli E, Romeo F, Fiorani S, Pezzimenti F, Casagrande F, Costa I, Parazzoli D, Costanzo V., Nat Commun. March 12, 2020; 11 (1): 1345.
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines. , Gardner NJ, Gillespie PJ, Carrington JT, Shanks EJ, McElroy SP, Haagensen EJ, Frearson JA, Woodland A, Blow JJ ., Cell Chem Biol. August 17, 2017; 24 (8): 981-992.e4.
Rethinking origin licensing. , Bell SP., Elife. January 19, 2017; 6
Structure of human Cdc45 and implications for CMG helicase function. , Simon AC, Sannino V, Costanzo V, Pellegrini L., Nat Commun. May 18, 2016; 7 11638.
The centrosome and its duplication cycle. , Fu J, Hagan IM, Glover DM., Cold Spring Harb Perspect Biol. February 2, 2015; 7 (2): a015800.
Quantitative proteomics of Xenopus laevis embryos: expression kinetics of nearly 4000 proteins during early development. , Sun L, Bertke MM, Champion MM , Zhu G, Huber PW , Dovichi NJ ., Sci Rep. February 26, 2014; 4 4365.
Mta2 promotes Tipin-dependent maintenance of replication fork integrity. , Errico A, Aze A, Costanzo V., Cell Cycle. January 1, 2014; 13 (13): 2120-8.
Human origin recognition complex binds preferentially to G-quadruplex-preferable RNA and single-stranded DNA. , Hoshina S, Yura K, Teranishi H, Kiyasu N, Tominaga A, Kadoma H, Nakatsuka A, Kunichika T, Obuse C, Waga S., J Biol Chem. October 18, 2013; 288 (42): 30161-30171.
Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts. , Taylor EM, Bonsu NM, Price RJ, Lindsay HD ., Nucleic Acids Res. September 1, 2013; 41 (16): 7725-37.
Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos. , Kisielewska J , Blow JJ ., Development. January 1, 2012; 139 (1): 63-74.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
Tipin/ Tim1/ And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. , Errico A, Cosentino C, Rivera T, Losada A, Schwob E, Hunt T , Costanzo V., EMBO J. December 2, 2009; 28 (23): 3681-92.
A topoisomerase II-dependent mechanism for resetting replicons at the S-M-phase transition. , Cuvier O, Stanojcic S, Lemaitre JM, Mechali M ., Genes Dev. April 1, 2008; 22 (7): 860-5.
Studies of the properties of human origin recognition complex and its Walker A motif mutants. , Giordano-Coltart J, Ying CY, Gautier J , Hurwitz J ., Proc Natl Acad Sci U S A. January 4, 2005; 102 (1): 69-74.
Cell cycle dependent regulation of the origin recognition complex. , DePamphilis ML., Cell Cycle. January 1, 2005; 4 (1): 70-9.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M, Score AJ, Blow JJ ., J Cell Biol. April 26, 2004; 165 (2): 181-90.
Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle. , Okuno Y, McNairn AJ, den Elzen N, Pines J, Gilbert DM., EMBO J. August 1, 2001; 20 (15): 4263-77.
Repression of origin assembly in metaphase depends on inhibition of RLF-B/ Cdt1 by geminin. , Tada S, Li A, Maiorano D , Méchali M, Blow JJ ., Nat Cell Biol. February 1, 2001; 3 (2): 107-13.
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. , Gillespie PJ, Li A, Blow JJ ., BMC Biochem. January 1, 2001; 2 15.
Identification and characterization of the human ORC6 homolog. , Dhar SK, Dutta A ., J Biol Chem. November 10, 2000; 275 (45): 34983-8.
Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals. , Natale DA, Li CJ, Sun WH, DePamphilis ML., EMBO J. June 1, 2000; 19 (11): 2728-38.
The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells. , Madine MA, Swietlik M, Pelizon C, Romanowski P, Mills AD, Laskey RA., J Struct Biol. April 1, 2000; 129 (2-3): 198-210.
Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. , Findeisen M, El-Denary M, Kapitza T, Graf R, Strausfeld U., Eur J Biochem. September 1, 1999; 264 (2): 415-26.
Mouse homolog of the yeast origin recognition complex subunit ORC1 and chromosomal localization of the cognate mouse gene Orc1. , Zisimopoulou P, Staib C, Nanda I, Schmid M, Grummt F., Mol Gen Genet. November 1, 1998; 260 (2-3): 295-9.
Interaction between the origin recognition complex and the replication licensing system in Xenopus. , Rowles A , Chong JP, Brown L, Howell M, Evan GI, Blow JJ ., Cell. October 18, 1996; 87 (2): 287-96.