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Summary Expression Phenotypes Gene Literature (174) GO Terms (10) Nucleotides (88) Proteins (45) Interactants (552) Wiki
XB-GENEPAGE-487473

Papers associated with nodal2



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Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus., Cha YR, Takahashi S, Wright CV., Dev Biol. February 15, 2006; 290 (2): 246-64.                        

Global analysis of the transcriptional network controlling Xenopus endoderm formation., Sinner D, Kirilenko P, Rankin S, Rankin S, Wei E, Howard L, Kofron M, Heasman J, Woodland HR, Zorn AM., Development. May 1, 2006; 133 (10): 1955-66.              

Nodal-related gene Xnr5 is amplified in the Xenopus genome., Takahashi S, Onuma Y, Yokota C, Westmoreland JJ, Asashima M, Wright CV., Genesis. July 1, 2006; 44 (7): 309-21.          

Xenopus POU factors of subclass V inhibit activin/nodal signaling during gastrulation., Cao Y, Siegel D, Knöchel W., Mech Dev. August 1, 2006; 123 (8): 614-25.            

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal., Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM., Development. September 1, 2006; 133 (18): 3709-22.                                    

Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine., Kloda A, Adams DJ., Br J Pharmacol. September 1, 2006; 149 (2): 163-9.

ADMP2 is essential for primitive blood and heart development in Xenopus., Kumano G, Ezal C, Smith WC., Dev Biol. November 15, 2006; 299 (2): 411-23.                

FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development., Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS., Development. December 1, 2006; 133 (24): 4827-38.                    

NR3A modulates the outer vestibule of the "NMDA" receptor channel., Wada A, Takahashi H, Lipton SA, Chen HS., J Neurosci. December 20, 2006; 26 (51): 13156-66.

PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating., Lin Y, Jover-Mengual T, Wong J, Bennett MV, Zukin RS., Proc Natl Acad Sci U S A. December 26, 2006; 103 (52): 19902-7.              

Cyclophane and acyclic cyclophane: novel channel blockers of N-methyl-D-aspartate receptor., Masuko T, Nagaoka H, Miyake M, Metori K, Kizawa Y, Kashiwagi K, Igarashi K, Kusama T., Neurochem Int. January 1, 2007; 50 (2): 443-9.

XSu(H)2 is an essential factor for gene expression and morphogenesis of the Xenopus gastrula embryo., Ito M, Katada T, Miyatani S, Kinoshita T., Int J Dev Biol. January 1, 2007; 51 (1): 27-36.            

Xenopus Suppressor of Hairless 2 is involved in the cell fate decision during gastrulation through the transcriptional regulation of Xoct25/91., Ito M, Nishitani E, Kinoshita T., Biochem Biophys Res Commun. February 16, 2007; 353 (3): 644-9.        

Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function., Madry C, Mesic I, Bartholomäus I, Nicke A, Betz H, Laube B., Biochem Biophys Res Commun. March 2, 2007; 354 (1): 102-8.

Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating., Sobolevsky AI, Prodromou ML, Yelshansky MV, Wollmuth LP., J Gen Physiol. June 1, 2007; 129 (6): 509-25.                    

The Sox axis, Nodal signaling, and germ layer specification., Zhang C, Klymkowsky MW., Differentiation. July 1, 2007; 75 (6): 536-45.          

Xenopus Lefty requires proprotein cleavage but not N-linked glycosylation to inhibit nodal signaling., Westmoreland JJ, Takahashi S, Wright CV., Dev Dyn. August 1, 2007; 236 (8): 2050-61.        

Cleft-type cyclophanes confer neuroprotection against excitatory neurotoxicity in vitro and in vivo through inhibition of NMDA receptors., Masuko T, Nemoto Y, Nagaoka H, Miyake M, Kizawa Y, Kusama-Eguchi K, Kashiwagi K, Igarashi K, Kusama T., Neuropharmacology. September 1, 2007; 53 (4): 515-23.

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors., Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF., Mol Pharmacol. October 1, 2007; 72 (4): 907-20.

Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., Morris SA, Almeida AD, Tanaka H, Ohta K, Ohnuma S., PLoS One. October 10, 2007; 2 (10): e1004.                    

Regulation of the response to Nodal-mediated mesoderm induction by Xrel3., Kennedy MW, Green KA, Ford RL, Andrews PG, Paterno GD, Gillespie LL, Kao KR., Dev Biol. November 15, 2007; 311 (2): 383-95.      

Hes6 is required for MyoD induction during gastrulation., Murai K, Vernon AE, Philpott A, Jones P., Dev Biol. December 1, 2007; 312 (1): 61-76.            

The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors., Madry C, Mesic I, Betz H, Laube B., Mol Pharmacol. December 1, 2007; 72 (6): 1535-44.

Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes., Wrighton DC, Baker EJ, Chen PE, Wyllie DJ., J Physiol. January 1, 2008; 586 (1): 211-25.

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes., Chen PE, Geballe MT, Katz E, Erreger K, Livesey MR, O'Toole KK, Le P, Lee CJ, Lee CJ, Snyder JP, Traynelis SF, Wyllie DJ., J Physiol. January 1, 2008; 586 (1): 227-45.

Modulation of NMDA receptor properties and synaptic transmission by the NR3A subunit in mouse hippocampal and cerebrocortical neurons., Tong G, Takahashi H, Tu S, Shin Y, Talantova M, Zago W, Xia P, Nie Z, Goetz T, Zhang D, Lipton SA, Nakanishi N., J Neurophysiol. January 1, 2008; 99 (1): 122-32.

Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly., Schüler T, Mesic I, Madry C, Bartholomäus I, Laube B., J Biol Chem. January 4, 2008; 283 (1): 37-46.

Apparent homomeric NR1 currents observed in Xenopus oocytes are caused by an endogenous NR2 subunit., Schmidt C, Hollmann M., J Mol Biol. February 22, 2008; 376 (3): 658-70.

Activin/nodal signaling modulates XPAPC expression during Xenopus gastrulation., Lou X, Li S, Wang J, Ding X., Dev Dyn. March 1, 2008; 237 (3): 683-91.        

The NR1 M3 domain mediates allosteric coupling in the N-methyl-D-aspartate receptor., Blanke ML, VanDongen AM., Mol Pharmacol. August 1, 2008; 74 (2): 454-65.

Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds., Blanke ML, VanDongen AM., J Biol Chem. August 1, 2008; 283 (31): 21519-29.

Rules of engagement for NMDA receptor subunits., Ulbrich MH, Isacoff EY., Proc Natl Acad Sci U S A. September 16, 2008; 105 (37): 14163-8.

Different structural requirements for functional ion pore transplantation suggest different gating mechanisms of NMDA and kainate receptors., Villmann C, Hoffmann J, Werner M, Kott S, Strutz-Seebohm N, Nilsson T, Hollmann M., J Neurochem. October 1, 2008; 107 (2): 453-65.

Molecular determinants of multiple effects of nickel on NMDA receptor channels., Gavazzo P, Guida P, Zanardi I, Marchetti C., Neurotox Res. January 1, 2009; 15 (1): 38-48.

Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes., Puddifoot CA, Chen PE, Schoepfer R, Wyllie DJ., Br J Pharmacol. February 1, 2009; 156 (3): 509-18.

Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors., Cavara NA, Orth A, Hollmann M., BMC Neurosci. April 6, 2009; 10 32.      

Tumor necrosis factor-receptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation., Kalkan T, Iwasaki Y, Park CY, Thomsen GH., Mol Biol Cell. July 1, 2009; 20 (14): 3436-50.                          

Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles., Ewald RC, Cline HT., Front Mol Neurosci. September 11, 2009; 2 4.          

Control of NMDA receptor function by the NR2 subunit amino-terminal domain., Yuan H, Hansen KB, Vance KM, Ogden KK, Traynelis SF., J Neurosci. September 30, 2009; 29 (39): 12045-58.

N-methyl-D-aspartate (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives: preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse., Costa BM, Feng B, Tsintsadze TS, Morley RM, Irvine MW, Tsintsadze V, Lozovaya NA, Jane DE, Monaghan DT., J Pharmacol Exp Ther. November 1, 2009; 331 (2): 618-26.

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway., Luxardi G, Marchal L, Thomé V, Kodjabachian L., Development. February 1, 2010; 137 (3): 417-26.          

Structural determinants of D-cycloserine efficacy at the NR1/NR2C NMDA receptors., Dravid SM, Burger PB, Prakash A, Geballe MT, Yadav R, Le P, Vellano K, Snyder JP, Traynelis SF., J Neurosci. February 17, 2010; 30 (7): 2741-54.

Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+ block., Cavara NA, Orth A, Hicking G, Seebohm G, Hollmann M., BMC Neurosci. October 19, 2010; 11 133.          

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis., Vonica A, Rosa A, Arduini BL, Brivanlou AH., Dev Biol. February 1, 2011; 350 (1): 13-23.                

Novel functions of Noggin proteins: inhibition of Activin/Nodal and Wnt signaling., Bayramov AV, Eroshkin FM, Martynova NY, Ermakova GV, Solovieva EA, Zaraisky AG., Development. December 1, 2011; 138 (24): 5345-56.              

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells., Miyazaki A, Ishii K, Yamashita S, Nejigane S, Matsukawa S, Ito Y, Onuma Y, Asashima M, Michiue T., PLoS One. January 1, 2012; 7 (10): e46630.        

A developmental requirement for HIRA-dependent H3.3 deposition revealed at gastrulation in Xenopus., Szenker E, Lacoste N, Almouzni G., Cell Rep. June 28, 2012; 1 (6): 730-40.                                      

Klf4 is required for germ-layer differentiation and body axis patterning during Xenopus embryogenesis., Cao Q, Zhang X, Lu L, Yang L, Gao J, Gao Y, Ma H, Cao Y., Development. November 1, 2012; 139 (21): 3950-61.                  

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis., Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M., Genes Dev. December 1, 2012; 26 (23): 2567-79.      

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                

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