???pagination.result.count???
???pagination.result.page???
1
The cell nucleus in early bovine and caprine preimplantation embryos: fine structural cytochemistry and immunoelectron microscopy. , Kopecny V, Biggiogera M, Pivko J, Grafenau P, Pavlok A, Malatesta M, Martin TE, Fakan S., Eur J Cell Biol. August 1, 1996; 70 (4): 361-72.
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. , Kapoor TM, Mayer TU , Coughlin ML, Mitchison TJ ., J Cell Biol. September 4, 2000; 150 (5): 975-88.
Novel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces. , Dong K, Tang LQ, MacGregor GG, Leng Q, Hebert SC., EMBO J. April 6, 2005; 24 (7): 1318-29.
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. , You Z, Chahwan C, Bailis J, Hunter T, Russell P., Mol Cell Biol. July 1, 2005; 25 (13): 5363-79.
Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11. , Di Virgilio M, Gautier J ., J Cell Biol. December 5, 2005; 171 (5): 765-71.
ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks. , Trenz K, Smith E, Smith S, Costanzo V., EMBO J. April 19, 2006; 25 (8): 1764-74.
Two-step activation of ATM by DNA and the Mre11- Rad50- Nbs1 complex. , Dupré A , Boyer-Chatenet L, Gautier J ., Nat Struct Mol Biol. May 1, 2006; 13 (5): 451-7.
Rapid activation of ATM on DNA flanking double-strand breaks. , You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T., Nat Cell Biol. November 1, 2007; 9 (11): 1311-8.
Telomere capping and cellular checkpoints: clues from fruit flies. , Ciapponi L, Cenci G., Cytogenet Genome Res. January 1, 2008; 122 (3-4): 365-73.
A forward chemical genetic screen reveals an inhibitor of the Mre11- Rad50- Nbs1 complex. , Dupré A , Boyer-Chatenet L, Sattler RM, Modi AP, Lee JH , Nicolette ML, Kopelovich L, Jasin M, Baer R, Paull TT, Gautier J ., Nat Chem Biol. February 1, 2008; 4 (2): 119-25.
Mre11- Rad50- Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. , Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V., EMBO J. July 23, 2008; 27 (14): 1953-62.
Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. , Xu C, Wu L, Cui G, Botuyan MV, Chen J , Mer G., J Mol Biol. August 29, 2008; 381 (2): 361-72.
The Mre11- Rad50- Nbs1 complex mediates activation of TopBP1 by ATM. , Yoo HY, Kumagai A , Shevchenko A, Shevchenko A, Dunphy WG ., Mol Biol Cell. May 1, 2009; 20 (9): 2351-60.
PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin. , Di Virgilio M, Ying CY, Gautier J ., DNA Repair (Amst). November 2, 2009; 8 (11): 1311-20.
CtIP links DNA double-strand break sensing to resection. , You Z, Shi LZ, Zhu Q, Wu P, Zhang YW , Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T., Mol Cell. December 25, 2009; 36 (6): 954-69.
The Mre11/ Rad50/ Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis. , Taylor EM, Cecillon SM, Bonis A, Chapman JR, Povirk LF, Lindsay HD ., Nucleic Acids Res. January 1, 2010; 38 (2): 441-54.
Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/ Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM. , Wawrousek KE, Fortini BK, Polaczek P, Chen L, Liu Q, Dunphy WG , Campbell JL ., Cell Cycle. March 15, 2010; 9 (6): 1156-66.
Amino acid residues constituting the agonist binding site of the human P2X3 receptor. , Bodnar M, Wang H, Riedel T, Hintze S, Kato E, Fallah G, Gröger-Arndt H, Giniatullin R, Grohmann M, Hausmann R, Schmalzing G, Illes P, Rubini P., J Biol Chem. January 28, 2011; 286 (4): 2739-49.
CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts. , Ramírez-Lugo JS, Yoo HY, Yoon SJ , Dunphy WG ., Cell Cycle. February 1, 2011; 10 (3): 469-80.
Essential roles of Xenopus TRF2 in telomere end protection and replication. , Muraki K, Nabetani A, Nishiyama A, Ishikawa F ., Genes Cells. June 1, 2011; 16 (6): 728-39.
Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm. , Pieper M, Ahrens K , Rink E, Peter A, Schlosser G ., Development. March 1, 2012; 139 (6): 1175-87.
Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts. , Kumar S , Yoo HY, Kumagai A , Shevchenko A, Shevchenko A, Dunphy WG ., Cell Cycle. March 15, 2012; 11 (6): 1183-94.
Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice. , Chiruvella KK, Sebastian R, Sharma S, Karande AA, Choudhary B, Raghavan SC., J Mol Biol. March 30, 2012; 417 (3): 197-211.
Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks. , Liao S, Guay C, Toczylowski T, Yan H., Nucleic Acids Res. May 1, 2012; 40 (10): 4496-506.
Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC. , Reschen RF, Colombie N, Wheatley L, Dobbelaere J, St Johnston D, Ohkura H, Raff JW., Biol Open. May 15, 2012; 1 (5): 422-9.
The MRN- CtIP pathway is required for metaphase chromosome alignment. , Rozier L, Guo Y, Peterson S, Sato M, Baer R, Gautier J , Mao Y., Mol Cell. March 28, 2013; 49 (6): 1097-107.
A role for the MRN complex in ATR activation via TOPBP1 recruitment. , Duursma AM, Driscoll R, Elias JE, Cimprich KA., Mol Cell. April 11, 2013; 50 (1): 116-22.
The Mre11- Rad50- Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. , Lee J , Dunphy WG ., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
PCNA promotes processive DNA end resection by Exo1. , Chen X, Paudyal SC, Chin RI, You Z., Nucleic Acids Res. November 1, 2013; 41 (20): 9325-38.
Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division. , Grob A, McStay B., Cell Cycle. January 1, 2014; 13 (16): 2501-8.
Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators. , Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC., J Med Chem. March 27, 2014; 57 (6): 2334-56.
Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma. , Wylie LA, Hardwick LJ , Papkovskaia TD, Thiele CJ, Philpott A ., Dis Model Mech. May 1, 2015; 8 (5): 429-41.
MCM8-9 complex promotes resection of double-strand break ends by MRE11- RAD50- NBS1 complex. , Lee KY, Im JS, Shibata E, Park J , Handa N, Kowalczykowski SC, Dutta A ., Nat Commun. July 28, 2015; 6 7744.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS, Gambus A, Gillespie PJ, Blow JJ ., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses. , Choi SH, Yoo HY., Biochem Biophys Res Commun. October 7, 2016; 479 (1): 5-11.
Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining. , Zhu S, Fisher LA, Bessho T, Peng A ., Nucleic Acids Res. October 13, 2017; 45 (18): 10583-10594.
Dna2 initiates resection at clean DNA double-strand breaks. , Paudyal SC, Li S, Yan H, Hunter T, You Z., Nucleic Acids Res. November 16, 2017; 45 (20): 11766-11781.
Conservation and divergence of protein pathways in the vertebrate heart. , Federspiel JD, Tandon P , Wilczewski CM, Wasson L, Herring LE, Venkatesh SS, Cristea IM, Conlon FL ., PLoS Biol. September 6, 2019; 17 (9): e3000437.
ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR. , Gunkel P, Iino H, Krull S, Cordes VC., Cells. July 30, 2021; 10 (8):
MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks. , Montales K, Ruis K, Lindsay H , Michael WM., PLoS One. August 2, 2022; 17 (8): e0271905.
POLθ prevents MRE11- NBS1- CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps. , Mann A, Ramirez-Otero MA, De Antoni A, Hanthi YW, Sannino V, Baldi G, Falbo L, Schrempf A, Bernardo S, Loizou J, Costanzo V., Mol Cell. November 17, 2022; 82 (22): 4218-4231.e8.
Resection of DNA double-strand breaks activates Mre11- Rad50- Nbs1- and Rad9- Hus1- Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts. , Tatsukawa K, Sakamoto R, Kawasoe Y, Kubota Y, Tsurimoto T, Takahashi TS, Ohashi E., Nucleic Acids Res. April 12, 2024; 52 (6): 3146-3163.