Papers associated with lrp6

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	eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G., J Biol Chem. June 26, 2020; 295 (26): 8759-8774.
	TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9
	Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains., Kim J, Han W, Park T, Kim EJ, Bang I, Lee HS, Lee HS, Jeong Y, Roh K, Kim J, Kim JS, Kang C, Seok C, Han JK, Choi HJ., Nat Commun. October 23, 2020; 11 (1): 5357.
	R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.
	Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM., Sci Rep. December 9, 2020; 10 (1): 21555.
	Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis., Colozza G., MicroPubl Biol. January 5, 2021; 2021
	A catenin of the plakophilin-subfamily, Pkp3, responds to canonical-Wnt pathway components and signals., Hong JY, Zapata J, Blackburn A, Baumert R, Bae SM, Ji H, Nam HJ, Miller RK, McCrea PD., Biochem Biophys Res Commun. July 23, 2021; 563 31-39.
	Optogenetic Control of the Canonical Wnt Signaling Pathway During Xenopus laevis Embryonic Development., Krishnamurthy VV, Hwang H, Fu J, Yang J, Zhang K., J Mol Biol. September 3, 2021; 433 (18): 167050.
	Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P., Cells Tissues Organs. January 1, 2022; 211 (6): 736-753.
	LRP6 Receptor Plays Essential Functions in Development and Human Diseases., Alrefaei AF, Abu-Elmagd M., Genes (Basel). January 10, 2022; 13 (1):
	The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation., Niehrs C., Dev Biol. February 1, 2022; 482 1-6.
	Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.
	Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.
	Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants., Houston DW, Elliott KL, Coppenrath K, Wlizla M, Horb ME., Development. September 1, 2022; 149 (17):
	ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A, Cousin H, Horr B, Alfandari D, Alfandari D., Front Cell Dev Biol. January 1, 2023; 11 1271178.
	The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.
	Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis., Azbazdar Y, Tejeda-Munoz N, Monka JC, Dayrit A, Binder G, Ozhan G, De Robertis EM., iScience. October 20, 2023; 26 (10): 108075.
	The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking., Azbazdar Y, De Robertis EM., Bioessays. January 1, 2024; 46 (1): e2300179.
	R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.

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