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Summary Expression Phenotypes Gene Literature (190) GO Terms (26) Nucleotides (140) Proteins (57) Interactants (149) Wiki
XB-GENEPAGE-5921461

Papers associated with kcnq1



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Pharmacological activation of normal and arrhythmia-associated mutant KCNQ1 potassium channels., Seebohm G, Pusch M, Chen J, Sanguinetti MC., Circ Res. November 14, 2003; 93 (10): 941-7.

Tight coupling of rubidium conductance and inactivation in human KCNQ1 potassium channels., Seebohm G, Sanguinetti MC, Pusch M., J Physiol. October 15, 2003; 552 (Pt 2): 369-78.

Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex., Chen H, Kim LA, Rajan S, Xu S, Goldstein SA., Neuron. September 25, 2003; 40 (1): 15-23.

Characterization of a novel Long QT syndrome mutation G52R-KCNE1 in a Chinese family., Ma L, Lin C, Teng S, Chai Y, Bähring R, Vardanyan V, Li L, Pongs O, Hui R., Cardiovasc Res. September 1, 2003; 59 (3): 612-9.

Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels., Ljungstrom T, Grunnet M, Jensen BS, Olesen SP., Pflugers Arch. September 1, 2003; 446 (6): 684-94.

Molecular determinants of KCNQ1 channel block by a benzodiazepine., Seebohm G, Chen J, Strutz N, Culberson C, Lerche C, Sanguinetti MC., Mol Pharmacol. July 1, 2003; 64 (1): 70-7.

Pore- and state-dependent cadmium block of I(Ks) channels formed with MinK-55C and wild-type KCNQ1 subunits., Chen H, Sesti F, Goldstein SA., Biophys J. June 1, 2003; 84 (6): 3679-89.

KCNQ1 channels sense small changes in cell volume., Grunnet M, Jespersen T, MacAulay N, Jørgensen NK, Schmitt N, Pongs O, Olesen SP, Klaerke DA., J Physiol. June 1, 2003; 549 (Pt 2): 419-27.

C-terminal interaction of KCNQ2 and KCNQ3 K+ channels., Maljevic S, Lerche C, Seebohm G, Alekov AK, Busch AE, Lerche H., J Physiol. April 15, 2003; 548 (Pt 2): 353-60.

Novel gene hKCNE4 slows the activation of the KCNQ1 channel., Teng S, Ma L, Zhen Y, Lin C, Bähring R, Vardanyan V, Pongs O, Hui R., Biochem Biophys Res Commun. April 11, 2003; 303 (3): 808-13.

RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW., J Biol Chem. April 4, 2003; 278 (14): 11739-45.

Clinical and electrophysiological characterization of a novel mutation (F193L) in the KCNQ1 gene associated with long QT syndrome., Yamaguchi M, Shimizu M, Ino H, Terai H, Hayashi K, Mabuchi H, Hoshi N, Higashida H., Clin Sci (Lond). April 1, 2003; 104 (4): 377-82.

C-terminal domains implicated in the functional surface expression of potassium channels., Jenke M, Sánchez A, Monje F, Stühmer W, Weseloh RM, Pardo LA., EMBO J. February 3, 2003; 22 (3): 395-403.

Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms., Embark HM, Böhmer C, Vallon V, Luft F, Lang F., Pflugers Arch. February 1, 2003; 445 (5): 601-6.

P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport., Köttgen M, Löffler T, Jacobi C, Nitschke R, Pavenstädt H, Schreiber R, Frische S, Nielsen S, Leipziger J., J Clin Invest. February 1, 2003; 111 (3): 371-9.

A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly., Schwake M, Jentsch TJ, Friedrich T., EMBO Rep. January 1, 2003; 4 (1): 76-81.

Modulation of homomeric and heteromeric KCNQ1 channels by external acidification., Peretz A, Schottelndreier H, Aharon-Shamgar LB, Attali B., J Physiol. December 15, 2002; 545 (3): 751-66.

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current., Angelo K, Jespersen T, Grunnet M, Nielsen MS, Klaerke DA, Olesen SP., Biophys J. October 1, 2002; 83 (4): 1997-2006.

KCNE4 is an inhibitory subunit to the KCNQ1 channel., Grunnet M, Jespersen T, Rasmussen HB, Ljungstrøm T, Jorgensen NK, Olesen SP, Klaerke DA., J Physiol. July 1, 2002; 542 (Pt 1): 119-30.

A truncated splice variant of KCNQ1 cloned from rat heart., Yamada Y, Chen X, Kobayashi T, Kamada Y, Nagashima M, Tsutsuura M, Seki S, Yamakage M, Namiki A, Tohse N., Biochem Biophys Res Commun. June 7, 2002; 294 (2): 199-204.

The oxidant thimerosal modulates gating behavior of KCNQ1 by interaction with the channel outer shell., Kerst G, Brousos H, Schreiber R, Nitschke R, Hug MJ, Greger R, Bleich M., J Membr Biol. March 15, 2002; 186 (2): 89-100.

A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B., Seebohm G, Lerche C, Pusch M, Steinmeyer K, Brüggemann A, Busch AE., Br J Pharmacol. December 1, 2001; 134 (8): 1647-54.

Properties and function of KCNQ1 K+ channels isolated from the rectal gland of Squalus acanthias., Kerst G, Beschorner U, Unsöld B, von Hahn T, Schreiber R, Greger R, Gerlach U, Lang HJ, Kunzelmann K, Bleich M., Pflugers Arch. October 1, 2001; 443 (1): 146-54.

Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium., MacVinish LJ, Guo Y, Dixon AK, Murrell-Lagnado RD, Cuthbert AW., Mol Pharmacol. October 1, 2001; 60 (4): 753-60.

Dependence of I(Ks) biophysical properties on the expression system., Seebohm G, Lerche C, Busch AE, Bachmann A., Pflugers Arch. September 1, 2001; 442 (6): 891-5.

A spectrum of functional effects for disease causing mutations in the Jervell and Lange-Nielsen syndrome., Huang L, Bitner-Glindzicz M, Tranebjaerg L, Tinker A., Cardiovasc Res. September 1, 2001; 51 (4): 670-80.

Regulation and properties of KCNQ1 (K(V)LQT1) and impact of the cystic fibrosis transmembrane conductance regulator., Boucherot A, Schreiber R, Kunzelmann K., J Membr Biol. July 1, 2001; 182 (1): 39-47.

Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome., Seebohm G, Scherer CR, Busch AE, Lerche C., J Biol Chem. April 27, 2001; 276 (17): 13600-5.

KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology., Søgaard R, Ljungstrøm T, Pedersen KA, Olesen SP, Jensen BS., Am J Physiol Cell Physiol. April 1, 2001; 280 (4): C859-66.

KCNE1 reverses the response of the human K+ channel KCNQ1 to cytosolic pH changes and alters its pharmacology and sensitivity to temperature., Unsöld B, Kerst G, Brousos H, Hübner M, Schreiber R, Nitschke R, Greger R, Bleich M., Pflugers Arch. December 1, 2000; 441 (2-3): 368-78.

Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols., Lerche C, Seebohm G, Wagner CI, Scherer CR, Dehmelt L, Abitbol I, Gerlach U, Brendel J, Attali B, Busch AE., Br J Pharmacol. December 1, 2000; 131 (8): 1503-6.

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel., Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J., EMBO J. December 1, 2000; 19 (23): 6326-30.

Mechanisms of I(Ks) suppression in LQT1 mutants., Bianchi L, Priori SG, Napolitano C, Surewicz KA, Dennis AT, Memmi M, Schwartz PJ, Brown AM., Am J Physiol Heart Circ Physiol. December 1, 2000; 279 (6): H3003-11.

Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991., Wang HS, Brown BS, McKinnon D, Cohen IS., Mol Pharmacol. June 1, 2000; 57 (6): 1218-23.

A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly., Schmitt N, Schwarz M, Peretz A, Abitbol I, Attali B, Pongs O., EMBO J. February 1, 2000; 19 (3): 332-40.

A constitutively open potassium channel formed by KCNQ1 and KCNE3., Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ., Nature. January 13, 2000; 403 (6766): 196-9.

Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels., Pusch M, Bertorello L, Conti F., Biophys J. January 1, 2000; 78 (1): 211-26.

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness., Kubisch C, Schroeder BC, Friedrich T, Lütjohann B, El-Amraoui A, Marlin S, Petit C, Jentsch TJ., Cell. February 5, 1999; 96 (3): 437-46.

Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias., Waldegger S, Fakler B, Bleich M, Barth P, Hopf A, Schulte U, Busch AE, Aller SG, Forrest JN, Greger R, Lang F., Pflugers Arch. January 1, 1999; 437 (2): 298-304.

Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy., Yang WP, Levesque PC, Little WA, Conder ML, Ramakrishnan P, Neubauer MG, Blanar MA., J Biol Chem. July 31, 1998; 273 (31): 19419-23.

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