Papers associated with kcnq1

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	The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes., Li W, Du R, Wang QF, Tian L, Yang JG, Song ZF., Biochem Biophys Res Commun. May 29, 2009; 383 (2): 206-9.
	Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity., Regev N, Degani-Katzav N, Korngreen A, Etzioni A, Siloni S, Alaimo A, Chikvashvili D, Villarroel A, Attali B, Lotan I., PLoS One. August 13, 2009; 4 (8): e6586.
	KCNQ1/KCNE1 assembly, co-translation not required., Vanoye CG, Welch RC, Tian C, Sanders CR, George AL., Channels (Austin). January 1, 2010; 4 (2): 108-14.
	PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions., Matavel A, Medei E, Lopes CM., Channels (Austin). January 1, 2010; 4 (1): 3-11.
	Functional delivery of a membrane protein into oocyte membranes using bicelles., Kang C, Vanoye CG, Welch RC, Van Horn WD, Sanders CR., Biochemistry. February 2, 2010; 49 (4): 653-5.
	A shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensor., Choi E, Abbott GW., FASEB J. May 1, 2010; 24 (5): 1518-24.
	State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation., Wu D, Delaloye K, Zaydman MA, Nekouzadeh A, Rudy Y, Cui J., J Gen Physiol. June 1, 2010; 135 (6): 595-606.
	Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit., Choi SH, Shin TJ, Lee BH, Chu DH, Choe H, Pyo MK, Hwang SH, Kim BR, Lee SM, Lee JH, Lee JH, Kim DH, Kim HC, Rhim HW, Nah SY., Eur J Pharmacol. July 10, 2010; 637 (1-3): 138-47.
	Stoichiometry of the KCNQ1 - KCNE1 ion channel complex., Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY., Proc Natl Acad Sci U S A. November 2, 2010; 107 (44): 18862-7.
	AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells., Alzamora R, Gong F, Rondanino C, Lee JK, Smolak C, Pastor-Soler NM, Hallows KR., Am J Physiol Renal Physiol. December 1, 2010; 299 (6): F1308-19.
	KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate., Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS., Proc Natl Acad Sci U S A. December 28, 2010; 107 (52): 22710-5.
	Structural basis of slow activation gating in the cardiac I Ks channel complex., Strutz-Seebohm N, Pusch M, Wolf S, Stoll R, Tapken D, Gerwert K, Attali B, Seebohm G., Cell Physiol Biochem. January 1, 2011; 27 (5): 443-52.
	Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase., Alesutan I, Föller M, Sopjani M, Dërmaku-Sopjani M, Zelenak C, Fröhlich H, Velic A, Fraser S, Kemp BE, Seebohm G, Völkl H, Lang F., Mol Membr Biol. February 1, 2011; 28 (2): 79-89.
	Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy., Wang YH, Jiang M, Xu XL, Hsu KL, Zhang M, Tseng GN., J Membr Biol. February 1, 2011; 239 (3): 137-56.
	Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis., Ma LJ, Ohmert I, Vardanyan V., Biophys J. February 16, 2011; 100 (4): 885-94.
	Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients., Jons C, O-Uchi J, Moss AJ, Reumann M, Rice JJ, Goldenberg I, Zareba W, Wilde AA, Shimizu W, Kanters JK, McNitt S, Hofman N, Robinson JL, Lopes CM., Sci Transl Med. March 30, 2011; 3 (76): 76ra28.
	Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Biochim Biophys Acta. April 1, 2011; 1812 (4): 488-94.
	KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity., Li Y, Zaydman MA, Wu D, Shi J, Guan M, Virgin-Downey B, Cui J., Proc Natl Acad Sci U S A. May 31, 2011; 108 (22): 9095-100.
	Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state., Larsen AP, Steffensen AB, Grunnet M, Olesen SP., Biophys J. August 17, 2011; 101 (4): 818-27.
	Identification and functional characterization of KCNQ1 mutations around the exon 7-intron 7 junction affecting the splicing process., Tsuji-Wakisaka K, Akao M, Ishii TM, Ashihara T, Makiyama T, Ohno S, Toyoda F, Dochi K, Matsuura H, Horie M., Biochim Biophys Acta. November 1, 2011; 1812 (11): 1452-9.
	KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue., Nakajo K, Nishino A, Okamura Y, Kubo Y., J Gen Physiol. November 1, 2011; 138 (5): 521-35.
	Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments., Coey AT, Sahu ID, Gunasekera TS, Troxel KR, Hawn JM, Swartz MS, Wickenheiser MR, Reid RJ, Welch RC, Vanoye CG, Kang C, Sanders CR, Lorigan GA., Biochemistry. December 20, 2011; 50 (50): 10851-9.
	Regulation of KCNQ1/KCNE1 by β-catenin., Wilmes J, Haddad-Tóvolli R, Alesutan I, Munoz C, Sopjani M, Pelzl L, Bogatikov E, Fedele G, Faggio C, Seebohm G, Föller M, Lang F., Mol Membr Biol. January 1, 2012; 29 (3-4): 87-94.
	Overlapping cardiac phenotype associated with a familial mutation in the voltage sensor of the KCNQ1 channel., Henrion U, Zumhagen S, Steinke K, Strutz-Seebohm N, Stallmeyer B, Lang F, Schulze-Bahr E, Seebohm G., Cell Physiol Biochem. January 1, 2012; 29 (5-6): 809-18.
	Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels., Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, Abriel H, Jespersen T., Heart Rhythm. March 1, 2012; 9 (3): 440-8.
	Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels., Osteen JD, Barro-Soria R, Robey S, Sampson KJ, Kass RS, Larsson HP., Proc Natl Acad Sci U S A. May 1, 2012; 109 (18): 7103-8.
	Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries., Chadha PS, Zunke F, Davis AJ, Jepps TA, Linders JT, Schwake M, Towart R, Greenwood IA., Br J Pharmacol. June 1, 2012; 166 (4): 1377-87.
	AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation., Föller M, Jaumann M, Dettling J, Saxena A, Pakladok T, Munoz C, Ruth P, Sopjani M, Seebohm G, Rüttiger L, Knipper M, Lang F., FASEB J. October 1, 2012; 26 (10): 4243-53.
	Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Gene. December 10, 2012; 511 (1): 26-33.
	Rab GTPases are required for early orientation of the left-right axis in Xenopus., Vandenberg LN, Morrie RD, Seebohm G, Lemire JM, Levin M., Mech Dev. January 1, 2013; 130 (4-5): 254-71.
	Chemical derivatization and purification of peptide-toxins for probing ion channel complexes., Hua Z, Kobertz WR., Methods Mol Biol. January 1, 2013; 995 19-30.
	Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges., Hammami S, Willumsen NJ, Meinild AK, Klaerke DA, Novak I., Acta Physiol (Oxf). March 1, 2013; 207 (3): 503-15.
	Dysfunctional potassium channel subunit interaction as a novel mechanism of long QT syndrome., Hoosien M, Ahearn ME, Myerburg RJ, Pham TV, Miller TE, Smets MJ, Baumbach-Reardon L, Young ML, Farooq A, Bishopric NH., Heart Rhythm. May 1, 2013; 10 (5): 728-37.
	Differential effects of ginsenoside metabolites on slowly activating delayed rectifier K(+) and KCNQ1 K(+) channel currents., Choi SH, Lee BH, Kim HJ, Jung SW, Hwang SH, Nah SY., J Ginseng Res. July 1, 2013; 37 (3): 324-31.
	Coxsackievirus B3 modulates cardiac ion channels., Steinke K, Sachse F, Ettischer N, Strutz-Seebohm N, Henrion U, Rohrbeck M, Klosowski R, Wolters D, Brunner S, Franz WM, Pott L, Munoz C, Kandolf R, Schulze-Bahr E, Lang F, Klingel K, Seebohm G., FASEB J. October 1, 2013; 27 (10): 4108-21.
	Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene., Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slanchev K, Hammerschmidt M, Topczewski J, Whitfield TT., Development. November 1, 2013; 140 (21): 4362-74.
	Intracellular ATP binding is required to activate the slowly activating K+ channel I(Ks)., Li Y, Gao J, Lu Z, McFarland K, Shi J, Bock K, Cohen IS, Cui J., Proc Natl Acad Sci U S A. November 19, 2013; 110 (47): 18922-7.
	Upregulation of KCNQ1/KCNE1 K+ channels by Klotho., Almilaji A, Pakladok T, Muñoz C, Elvira B, Sopjani M, Lang F., Channels (Austin). January 1, 2014; 8 (3): 222-9.
	KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability., Abbott GW, Tai KK, Neverisky DL, Hansler A, Hu Z, Roepke TK, Lerner DJ, Chen Q, Liu L, Zupan B, Toth M, Haynes R, Huang X, Demirbas D, Buccafusca R, Gross SS, Kanda VA, Berry GT., Sci Signal. March 4, 2014; 7 (315): ra22.
	Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel., Zaydman MA, Kasimova MA, McFarland K, Beller Z, Hou P, Kinser HE, Liang H, Zhang G, Shi J, Tarek M, Cui J., Elife. March 12, 2014; 3 e03606.
	Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1., Wu M, Obara Y, Norota I, Nagasawa Y, Ishii K., Pflugers Arch. May 1, 2014; 466 (5): 937-46.
	Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites., Choi SH, Lee BH, Kim HJ, Jung SW, Kim HS, Shin HC, Lee JH, Kim HC, Rhim H, Hwang SH, Ha TS, Kim HJ, Cho H, Nah SY., Mol Cells. September 1, 2014; 37 (9): 656-63.
	An Epithelial Ca2+-Sensor Protein is an Alternative to Calmodulin to Compose Functional KCNQ1 Channels., Inanobe A, Tsuzuki C, Kurachi Y., Cell Physiol Biochem. January 1, 2015; 36 (5): 1847-61.
	SPAK and OSR1 Sensitive Cell Membrane Protein Abundance and Activity of KCNQ1/E1 K+ Channels., Elvira B, Warsi J, Fezai M, Munoz C, Lang F., Cell Physiol Biochem. January 1, 2015; 37 (5): 2032-42.
	Regulation of Voltage Gated K+ Channel KCNE1/KCNQ1 by the Janus Kinase JAK3., Warsi J, Abousaab A, Fezai M, Elvira B, Lang F., Cell Physiol Biochem. January 1, 2015; 37 (6): 2476-85.
	High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance., Steffensen AB, Refaat MM, David JP, Mujezinovic A, Calloe K, Wojciak J, Nussbaum RL, Scheinman MM, Schmitt N., Sci Rep. January 12, 2015; 5 10009.
	KCNE3 acts by promoting voltage sensor activation in KCNQ1., Barro-Soria R, Perez ME, Larsson HP., Proc Natl Acad Sci U S A. December 29, 2015; 112 (52): E7286-92.
	The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/KCNE1 channel sensitivity to 1-alkanols., Xie C, Liu HW, Pan N, Ding JP, Yao J., Acta Pharmacol Sin. January 1, 2016; 37 (1): 124-33.
	Iron Overload Leading to Torsades de Pointes in β-Thalassemia and Long QT Syndrome., Refaat MM, El Hage L, Steffensen AB, Hotait M, Schmitt N, Scheinman M, Badhwar N., Card Electrophysiol Clin. March 1, 2016; 8 (1): 247-56.
	Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome., Adams DS, Uzel SG, Akagi J, Wlodkowic D, Andreeva V, Yelick PC, Devitt-Lee A, Pare JF, Levin M., J Physiol. June 15, 2016; 594 (12): 3245-70.

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