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Summary Expression Phenotypes Gene Literature (308) GO Terms (6) Nucleotides (92) Proteins (53) Interactants (177) Wiki
XB-GENEPAGE-1004370

Papers associated with kcnj3



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Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes., Choi S, Jung SY, Ko YS, Koh SR, Rhim H, Nah SY., Mol Pharmacol. April 1, 2002; 61 (4): 928-35.

Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes., Takesono A, Nowak MW, Cismowski M, Duzic E, Lanier SM., J Biol Chem. April 19, 2002; 277 (16): 13827-30.

LB50053: a 5-hydroxytrypamine(1a) agent with a high binding affinity and a potency evoking a K(+) current., Kim HS, Cho T, Lee C, Lee C, Joo H, Kim S, Min CK., Pharmacology. August 1, 2002; 65 (4): 175-81.

Graded contribution of the Gbeta gamma binding domains to GIRK channel activation., Sadja R, Alagem N, Reuveny E., Proc Natl Acad Sci U S A. August 6, 2002; 99 (16): 10783-8.

Distinct sites on G protein beta gamma subunits regulate different effector functions., Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE., J Biol Chem. September 27, 2002; 277 (39): 36345-50.

Molecular determinants for activation of G-protein-coupled inward rectifier K+ (GIRK) channels by extracellular acidosis., Mao J, Li L, McManus M, Wu J, Cui N, Jiang C., J Biol Chem. November 29, 2002; 277 (48): 46166-71.

G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase., Lavine N, Ethier N, Oak JN, Pei L, Liu F, Trieu P, Rebois RV, Bouvier M, Hebert TE, Van Tol HH., J Biol Chem. November 29, 2002; 277 (48): 46010-9.

Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation., Zhang Q, Pacheco MA, Doupnik CA., J Physiol. December 1, 2002; 545 (2): 355-73.

Early embryonic expression of ion channels and pumps in chick and Xenopus development., Rutenberg J, Cheng SM, Levin M., Dev Dyn. December 1, 2002; 225 (4): 469-84.                            

A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating., Guo Y, Waldron GJ, Murrell-Lagnado R., J Biol Chem. December 13, 2002; 277 (50): 48289-94.

Opioid receptor coupling to GIRK channels. In vitro studies using a Xenopus oocyte expression system and in vivo studies on weaver mutant mice., Ikeda K, Yoshii M, Sora I, Kobayashi T., Methods Mol Med. January 1, 2003; 84 53-64.

Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation., Müllner D., Biophys J. February 1, 2003; 84 (2 Pt 1): 1399-409.

Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels., Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N., J Biol Chem. February 7, 2003; 278 (6): 3840-5.

Inhibition of G-protein-coupled inward rectifying K+ channels by intracellular acidosis., Mao J, Wu J, Chen F, Wang X, Jiang C., J Biol Chem. February 28, 2003; 278 (9): 7091-8.

Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac)., Kobayashi T, Washiyama K, Ikeda K., Br J Pharmacol. March 1, 2003; 138 (6): 1119-28.

Effects of extracellular sodium on mu-opioid receptors coupled to potassium channels coexpressed in Xenopus oocytes., Oz M, Spivak CE., Pflugers Arch. March 1, 2003; 445 (6): 716-20.

Serine 329 of the mu-opioid receptor interacts differently with agonists., Pil J, Tytgat J., J Pharmacol Exp Ther. March 1, 2003; 304 (3): 924-30.

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids., Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ., J Biol Chem. March 28, 2003; 278 (13): 11312-9.

Conformational rearrangements associated with the gating of the G protein-coupled potassium channel revealed by FRET microscopy., Riven I, Kalmanzon E, Segev L, Reuveny E., Neuron. April 24, 2003; 38 (2): 225-35.

Effects of ginsenoside on G protein-coupled inwardly rectifying K+ channel activity expressed in Xenopus oocytes., Choi S, Lee JH, Lee JH, Kim YI, Kang MJ, Rhim H, Lee SM, Nah SY., Eur J Pharmacol. May 9, 2003; 468 (2): 83-92.

RGS9 modulates dopamine signaling in the basal ganglia., Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, Neve RL, Lester HA, Simon MI, Nestler EJ., Neuron. June 19, 2003; 38 (6): 941-52.

The M2 muscarinic G-protein-coupled receptor is voltage-sensitive., Ben-Chaim Y, Tour O, Dascal N, Parnas I, Parnas H., J Biol Chem. June 20, 2003; 278 (25): 22482-91.

beta-Funaltrexamine, a gauge for the recognition site of wildtype and mutant H297Q mu-opioid receptors., Spivak CE, Beglan CL, Zöllner C, Surratt CK., Synapse. July 1, 2003; 49 (1): 55-60.

Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel., Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N., J Biol Chem. August 1, 2003; 278 (31): 29174-83.

The selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel., Claydon TW, Makary SY, Dibb KM, Boyett MR., J Biol Chem. December 12, 2003; 278 (50): 50654-63.

Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity., Peng L, Mirshahi T, Zhang H, Hirsch JP, Logothetis DE., J Biol Chem. December 12, 2003; 278 (50): 50203-11.

Measuring the modulatory effects of RGS proteins on GIRK channels., Doupnik CA, Jaén C, Zhang Q., Methods Enzymol. January 1, 2004; 389 131-54.

Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C., Mao J, Wang X, Chen F, Wang R, Rojas A, Shi Y, Piao H, Jiang C., Proc Natl Acad Sci U S A. January 27, 2004; 101 (4): 1087-92.

Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction., Zhang L, Lee JK, Lee JK, John SA, Uozumi N, Kodama I., J Biol Chem. February 20, 2004; 279 (8): 7037-47.

betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation., Finley M, Arrabit C, Fowler C, Suen KF, Slesinger PA., J Physiol. March 16, 2004; 555 (Pt 3): 643-57.

Molecular determinants responsible for differential cellular distribution of G protein-gated inwardly rectifying K+ channels., Mirshahi T, Logothetis DE., J Biol Chem. March 19, 2004; 279 (12): 11890-7.

G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes., Itzhaki Van-Ham I, Peleg S, Dascal N, Shapira H, Oron Y., FEBS Lett. April 23, 2004; 564 (1-2): 157-60.

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel., Ivanina T, Varon D, Peleg S, Rishal I, Porozov Y, Dessauer CW, Keren-Raifman T, Dascal N., J Biol Chem. April 23, 2004; 279 (17): 17260-8.

A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade., Dhingra A, Faurobert E, Dascal N, Sterling P, Vardi N., J Neurosci. June 23, 2004; 24 (25): 5684-93.

Gbetagamma-activated inwardly rectifying K(+) (GIRK) channel activation kinetics via Galphai and Galphao-coupled receptors are determined by Galpha-specific interdomain interactions that affect GDP release rates., Zhang Q, Dickson A, Doupnik CA., J Biol Chem. July 9, 2004; 279 (28): 29787-96.

The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus., Milovic S, Steinecker-Frohnwieser B, Schreibmayer W, Weigl LG., J Biol Chem. August 13, 2004; 279 (33): 34240-9.

Short variable sequence acquired in evolution enables selective inhibition of various inward-rectifier K+ channels., Ramu Y, Klem AM, Lu Z., Biochemistry. August 24, 2004; 43 (33): 10701-9.

Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users., Kobayashi T, Washiyama K, Ikeda K., Ann N Y Acad Sci. October 1, 2004; 1025 590-4.

K+ activation of kir3.1/kir3.4 and kv1.4 K+ channels is regulated by extracellular charges., Claydon TW, Makary SY, Dibb KM, Boyett MR., Biophys J. October 1, 2004; 87 (4): 2407-18.

Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs., Kobayashi T, Washiyama K, Ikeda K., Neuropsychopharmacology. October 1, 2004; 29 (10): 1841-51.

Carboxy-terminal determinants of conductance in inward-rectifier K channels., Zhang YY, Robertson JL, Gray DA, Palmer LG., J Gen Physiol. December 1, 2004; 124 (6): 729-39.                      

Effects of interferon-alpha on cloned opioid receptors expressed in Xenopus oocytes., Kobayashi T, Washiyama K, Ikeda K., Life Sci. December 10, 2004; 76 (4): 407-15.

RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat., Pertovaara A, Ostergård M, Ankö ML, Lehti-Koivunen S, Brandt A, Hong W, Korpi ER, Panula P., Neuroscience. January 1, 2005; 134 (3): 1023-32.

Kinetic modeling of Na(+)-induced, Gbetagamma-dependent activation of G protein-gated K(+) channels., Yakubovich D, Rishal I, Dascal N., J Mol Neurosci. January 1, 2005; 25 (1): 7-19.

Molecular cloning and characterization of a new RGS protein of Medaka., Itoh M, Nagatomo K, Kubo Y, Sugimoto M, Saitoh O., Gene. January 31, 2005; 345 (2): 165-71.

Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex., Clancy SM, Fowler CE, Finley M, Suen KF, Arrabit C, Berton F, Kosaza T, Casey PJ, Slesinger PA., Mol Cell Neurosci. February 1, 2005; 28 (2): 375-89.

Mutation of critical GIRK subunit residues disrupts N- and C-termini association and channel function., Sarac R, Hou P, Hurley KM, Hriciste D, Cohen NA, Nelson DJ., J Neurosci. February 16, 2005; 25 (7): 1836-46.

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification., Pegan S, Arrabit C, Zhou W, Kwiatkowski W, Collins A, Slesinger PA, Choe S., Nat Neurosci. March 1, 2005; 8 (3): 279-87.

Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels., Rishal I, Porozov Y, Yakubovich D, Varon D, Dascal N., J Biol Chem. April 29, 2005; 280 (17): 16685-94.

Phosphorylation of a tyrosine at the N-terminus regulates the surface expression of GIRK5 homomultimers., Mora SI, Escobar LI., FEBS Lett. June 6, 2005; 579 (14): 3019-23.

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