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Summary Expression Phenotypes Gene Literature (173) GO Terms (8) Nucleotides (126) Proteins (59) Interactants (935) Wiki
XB-GENEPAGE-487097

Papers associated with gsk3b



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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein., Liu J, Stevens J, Rote CA, Yost HJ, Hu Y, Neufeld KL, White RL, Matsunami N., Mol Cell. May 1, 2001; 7 (5): 927-36.

Missing links in GSK3 regulation., Dominguez I, Green JB., Dev Biol. July 15, 2001; 235 (2): 303-13.

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus., Li X, Yost HJ, Virshup DM, Seeling JM., EMBO J. August 1, 2001; 20 (15): 4122-31.

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon., Lee E, Lee E, Salic A, Kirschner MW., J Cell Biol. September 3, 2001; 154 (5): 983-93.                

Identification of the Axin and Frat binding region of glycogen synthase kinase-3., Fraser E, Young N, Dajani R, Franca-Koh J, Ryves J, Williams RS, Yeo M, Webster MT, Richardson C, Smalley MJ, Pearl LH, Harwood A, Dale TC., J Biol Chem. January 18, 2002; 277 (3): 2176-85.

TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling., Brantjes H, Barker N, van Es J, Clevers H., Biol Chem. February 1, 2002; 383 (2): 255-61.

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus., Jia J, Amanai K, Wang G, Tang J, Wang B, Jiang J., Nature. April 4, 2002; 416 (6880): 548-52.

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities., Delobel P, Flament S, Hamdane M, Delacourte A, Vilain JP, Buée L., FEBS Lett. April 10, 2002; 516 (1-3): 151-5.

Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin., Ferkey DM, Kimelman D., J Biol Chem. May 3, 2002; 277 (18): 16147-52.

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling., Schwarz-Romond T, Asbrand C, Bakkers J, Kühl M, Schaeffer HJ, Huelsken J, Behrens J, Hammerschmidt M, Birchmeier W., Genes Dev. August 15, 2002; 16 (16): 2073-84.

Regulated proteolysis of Xom mediates dorsoventral pattern formation during early Xenopus development., Zhu Z, Kirschner M., Dev Cell. October 1, 2002; 3 (4): 557-68.

Sox10 regulates the development of neural crest-derived melanocytes in Xenopus., Aoki Y, Saint-Germain N, Gyda M, Magner-Fink E, Lee YH, Lee YH, Credidio C, Saint-Jeannet JP., Dev Biol. July 1, 2003; 259 (1): 19-33.          

Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals., Monsoro-Burq AH, Fletcher RB, Harland RM., Development. July 1, 2003; 130 (14): 3111-24.                

The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway., Lee E, Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW., PLoS Biol. October 1, 2003; 1 (1): E10.                  

LKB1 (XEEK1) regulates Wnt signalling in vertebrate development., Ossipova O, Bardeesy N, DePinho RA, Green JB., Nat Cell Biol. October 1, 2003; 5 (10): 889-94.

GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs., Weaver C, Farr GH, Pan W, Rowning BA, Wang J, Mao J, Wu D, Li L, Larabell CA, Kimelman D., Development. November 1, 2003; 130 (22): 5425-36.              

GSK-3-selective inhibitors derived from Tyrian purple indirubins., Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, Greengard P., Chem Biol. December 1, 2003; 10 (12): 1255-66.

Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3., Sarkissian M, Mendez R, Richter JD., Genes Dev. January 1, 2004; 18 (1): 48-61.

Lkb1 and GSK3-beta: kinases at the center and poles of the action., Green JB., Cell Cycle. January 1, 2004; 3 (1): 12-4.

Characterization and functional analysis of the murine Frat2 gene., van Amerongen R, van der Gulden H, Bleeker F, Jonkers J, Berns A., J Biol Chem. June 25, 2004; 279 (26): 26967-74.

Xenopus XsalF: anterior neuroectodermal specification by attenuating cellular responsiveness to Wnt signaling., Onai T, Sasai N, Matsui M, Sasai Y., Dev Cell. July 1, 2004; 7 (1): 95-106.            

Move it or lose it: axis specification in Xenopus., Weaver C, Kimelman D., Development. August 1, 2004; 131 (15): 3491-9.          

Cross-regulation of Wnt signaling and cell adhesion., Schambony A, Kunz M, Gradl D., Differentiation. September 1, 2004; 72 (7): 307-18.

Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction., Monsoro-Burq AH, Wang E, Harland R., Dev Cell. February 1, 2005; 8 (2): 167-78.            

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

PR72, a novel regulator of Wnt signaling required for Naked cuticle function., Creyghton MP, Roël G, Eichhorn PJ, Hijmans EM, Maurer I, Destrée O, Bernards R., Genes Dev. February 1, 2005; 19 (3): 376-86.            

Frat is dispensable for canonical Wnt signaling in mammals., van Amerongen R, Nawijn M, Franca-Koh J, Zevenhoven J, van der Gulden H, Jonkers J, Berns A., Genes Dev. February 15, 2005; 19 (4): 425-30.

Wnt-dependent regulation of the E-cadherin repressor snail., Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ., J Biol Chem. March 25, 2005; 280 (12): 11740-8.

Re-evaluating the role of Frat in Wnt-signal transduction., van Amerongen R, Berns A., Cell Cycle. August 1, 2005; 4 (8): 1065-72.

beta-Catenin controls cell sorting at the notochord-somite boundary independently of cadherin-mediated adhesion., Reintsch WE, Habring-Mueller A, Wang RW, Schohl A, Fagotto F., J Cell Biol. August 15, 2005; 170 (4): 675-86.              

Early steps in neural crest specification., Barembaum M, Bronner-Fraser M., Semin Cell Dev Biol. December 1, 2005; 16 (6): 642-6.      

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation., Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, Okamura H, Woodgett J, He X., Nature. December 8, 2005; 438 (7069): 873-7.

The zic1 gene is an activator of Wnt signaling., Merzdorf CS, Sive HL., Int J Dev Biol. January 1, 2006; 50 (7): 611-7.              

[Molecular mechanism of axon guidance]., Goshima Y., Nihon Shinkei Seishin Yakurigaku Zasshi. June 1, 2006; 26 (3): 135-40.

The endocrine-disrupting compound, nonylphenol, inhibits neurotrophin-dependent neurite outgrowth., Bevan CL, Porter DM, Schumann CR, Bryleva EY, Hendershot TJ, Liu H, Howard MJ, Henderson LP., Endocrinology. September 1, 2006; 147 (9): 4192-204.

Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos., Liao G, Tao Q, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY., Proc Natl Acad Sci U S A. October 31, 2006; 103 (44): 16313-8.                    

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A., Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD., J Biol Chem. November 17, 2006; 281 (46): 35021-9.

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos., Nagano T, Takehara S, Takahashi M, Aizawa S, Yamamoto A., Development. December 1, 2006; 133 (23): 4643-54.                  

Nuclear localization signals of the E-cadherin transcriptional repressor Snail., Ko H, Kim HS, Kim NH, Lee SH, Kim KH, Hong SH, Yook JI., Cells Tissues Organs. January 1, 2007; 185 (1-3): 66-72.

Phosphorylation and functions of inhibitor-2 family of proteins., Li M, Satinover DL, Brautigan DL., Biochemistry. March 6, 2007; 46 (9): 2380-9.

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM., Cell. November 30, 2007; 131 (5): 980-93.      

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions., Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X., Development. January 1, 2008; 135 (2): 367-75.

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling., Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Xu Y, Lee SJ, Lee J, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC., PLoS One. January 1, 2008; 3 (12): e4046.          

Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians., Iglesias M, Gomez-Skarmeta JL, Saló E, Adell T., Development. April 1, 2008; 135 (7): 1215-21.  

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.        

Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation., Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H., J Proteome Res. July 1, 2008; 7 (7): 2860-71.

Possible involvement of phosphatidylinositol 3-kinase, but not protein kinase B or glycogen synthase kinase 3beta, in progesterone-induced oocyte maturation in the Japanese brown frog, Rana japonica., Ota R, Suwa K, Kotani T, Mita K, Yamashita M., Zoolog Sci. July 1, 2008; 25 (7): 773-81.

Integrating positional information at the level of Smad1/5/8., Eivers E, Fuentealba LC, De Robertis EM., Curr Opin Genet Dev. August 1, 2008; 18 (4): 304-10.

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6., Wu G, Huang H, Garcia Abreu J, He X., PLoS One. January 1, 2009; 4 (3): e4926.              

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