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Regulation of the voltage-insensitive step of HERG activation by extracellular pH. , Zhou Q, Bett GC., Am J Physiol Heart Circ Physiol. June 1, 2010; 298 (6): H1710-8.
Modification of hERG1 channel gating by Cd2+. , Abbruzzese J, Sachse FB, Tristani-Firouzi M, Sanguinetti MC., J Gen Physiol. August 1, 2010; 136 (2): 203-24.
Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B. , Sahoo N, Tröger J, Heinemann SH, Schönherr R., FEBS Lett. September 24, 2010; 584 (18): 3896-900.
Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis. , Fichtman B, Ramos C, Rasala B, Harel A, Forbes DJ., Mol Biol Cell. December 1, 2010; 21 (23): 4197-211.
Molecular determinants of human ether-à- go-go-related gene 1 ( hERG1) K+ channel activation by NS1643. , Grunnet M, Abbruzzese J, Sachse FB, Sanguinetti MC., Mol Pharmacol. January 1, 2011; 79 (1): 1-9.
hERG potassium channel gating is mediated by N- and C-terminal region interactions. , Gustina AS, Trudeau MC., J Gen Physiol. March 1, 2011; 137 (3): 315-25.
Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids. , Grevellec A, Graham A, Tucker AS ., Dev Biol. May 15, 2011; 353 (2): 194-205.
hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds. , Hishigaki H, Kuhara S., Database (Oxford). May 17, 2011; 2011 bar017.
Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a- go-go-related gene ( hERG) potassium channel. , de la Peña P, Alonso-Ron C, Machín A, Fernández-Trillo J, Carretero L, Domínguez P, Barros F., J Biol Chem. May 27, 2011; 286 (21): 19065-75.
Differential effects of ginsenoside metabolites on HERG k channel currents. , Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ , Oh JW, Bae CS, Lee SH, Nah SY., J Ginseng Res. June 1, 2011; 35 (2): 191-9.
Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction. , Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ , Jo SH, Choe H, Nah SY., Eur J Pharmacol. August 1, 2011; 663 (1-3): 59-67.
Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant. , Es-Salah-Lamoureux Z, Xiong PY, Goodchild SJ, Ahern CA, Fedida D., Biophys J. August 3, 2011; 101 (3): 662-70.
Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration. , Lee BH, Lee SH, Chu D, Hyun JW, Choe H, Choi BH, Jo SH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.
Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo. , Charalambous A, Antoniades I, Christodoulou N, Skourides PA ., J Nanobiotechnology. September 15, 2011; 9 37.
Molecular determinants for activation of human ether-à- go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide. , Garg V, Stary-Weinzinger A, Sachse F, Sanguinetti MC., Mol Pharmacol. October 1, 2011; 80 (4): 630-7.
Strong activation of ether-à- go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells. , Schuster AM, Glassmeier G, Bauer CK., Mol Pharmacol. November 1, 2011; 80 (5): 930-42.
Molecular coupling in the human ether-a- go-go-related gene-1 ( hERG1) K+ channel inactivation pathway. , Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M., J Biol Chem. November 11, 2011; 286 (45): 39091-9.
A unified anatomy ontology of the vertebrate skeletal system. , Dahdul WM, Balhoff JP, Blackburn DC , Diehl AD, Haendel MA, Hall BK , Lapp H , Lundberg JG, Mungall CJ, Ringwald M, Segerdell E , Van Slyke CE, Vickaryous MK, Westerfield M , Mabee PM ., PLoS One. January 1, 2012; 7 (12): e51070.
Pharmacophore modeling for hERG channel facilitation. , Yamakawa Y, Furutani K, Inanobe A, Ohno Y, Kurachi Y., Biochem Biophys Res Commun. February 3, 2012; 418 (1): 161-6.
Identification and functional characterization of the novel human ether-a- go-go-related gene ( hERG) R744P mutant associated with hereditary long QT syndrome 2. , Aidery P, Kisselbach J, Gaspar H, Baldea I, Schweizer PA, Becker R, Katus HA, Thomas D., Biochem Biophys Res Commun. February 24, 2012; 418 (4): 830-5.
The Xenopus retinal ganglion cell as a model neuron to study the establishment of neuronal connectivity. , McFarlane S , Lom B ., Dev Neurobiol. April 1, 2012; 72 (4): 520-36.
Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis. , Wiechmann AF , Sherry DM., J Comp Neurol. April 15, 2012; 520 (6): 1115-27.
Neural crest delamination and migration: from epithelium-to- mesenchyme transition to collective cell migration. , Theveneau E , Mayor R ., Dev Biol. June 1, 2012; 366 (1): 34-54.
Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis. , Van Slyke AC, Cheng YM, Mafi P, Allard CR, Hull CM, Shi YP , Claydon TW., Am J Physiol Cell Physiol. June 15, 2012; 302 (12): C1797-806.
Acute alteration of cardiac ECG, action potential, I(Kr) and the human ether-a- go-go-related gene ( hERG) K+ channel by PCB 126 and PCB 77. , Park MH, Park WS, Jo SH., Toxicol Appl Pharmacol. July 1, 2012; 262 (1): 60-9.
Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule. , Garg V, Sachse FB, Sanguinetti MC., J Gen Physiol. September 1, 2012; 140 (3): 307-24.
Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels. , Tan PS, Perry MD , Ng CA, Vandenberg JI, Hill AP., J Gen Physiol. September 1, 2012; 140 (3): 293-306.
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins. , Peigneur S, Béress L, Möller C, Marí F, Forssmann WG, Tytgat J., FASEB J. December 1, 2012; 26 (12): 5141-51.
Serotonin has early, cilia-independent roles in Xenopus left- right patterning. , Vandenberg LN, Lemire JM , Levin M ., Dis Model Mech. January 1, 2013; 6 (1): 261-8.
Blocking of the human ether-à- go-go-related gene channel by imatinib mesylate. , Dong Q, Fu XX, Du LL, Zhao N, Xia CK, Yu KW, Cheng LX, Du YM., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.
[Follicular cells of the amphibian ovary: origin, structure, and functions]. , Konduktorova VV, Luchinskaia NN., Ontogenez. January 1, 2013; 44 (5): 316-30.
The eag domain regulates hERG channel inactivation gating via a direct interaction. , Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. , Long HK, Sims D , Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R , Ponting CP, Klose RJ., Elife. February 26, 2013; 2 e00348.
Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration. , Hong HK, Lee BH, Park MH, Lee SH, Chu D, Kim WJ, Choe H, Hee Choi B, Jo SH., Eur J Pharmacol. February 28, 2013; 702 (1-3): 165-73.
Flavonoid regulation of EAG1 channels. , Carlson AE, Brelidze TI, Zagotta WN., J Gen Physiol. March 1, 2013; 141 (3): 347-58.
ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels. , Garg V, Stary-Weinzinger A, Sanguinetti MC., Mol Pharmacol. April 1, 2013; 83 (4): 805-13.
Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels. , de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F., Biochem J. May 1, 2013; 451 (3): 463-74.
External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor. , Kazmierczak M, Zhang X, Chen B, Mulkey DK, Shi Y , Wagner PG, Pivaroff-Ward K, Sassic JK, Bayliss DA, Jegla T., J Gen Physiol. June 1, 2013; 141 (6): 721-35.
The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium. , Dou Y, Goodchild SJ, Velde RV, Wu Y, Fedida D., Am J Physiol Cell Physiol. August 15, 2013; 305 (4): C468-78.
Blockade of the human ether-a- go-go-related gene potassium channel by ketamine. , Zhang P, Xing J, Luo A, Feng J, Liu Z, Gao C, Ma J., J Pharm Pharmacol. September 1, 2013; 65 (9): 1321-8.
Exotic models may offer unique opportunities to decipher specific scientific question: the case of Xenopus olfactory system. , Gascuel J , Amano T ., Anat Rec (Hoboken). September 1, 2013; 296 (9): 1453-61.
Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels. , Cheng YM, Hull CM, Niven CM, Qi J, Allard CR, Claydon TW., J Gen Physiol. September 1, 2013; 142 (3): 289-303.
Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels. , Perry MD , Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.
Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel. , Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.
AMP-activated protein kinase regulates hERG potassium channel. , Almilaji A, Munoz C, Elvira B, Fajol A, Pakladok T, Honisch S, Shumilina E, Lang F , Föller M., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.
Up-regulation of hERG K⁺ channels by B-RAF. , Pakladok T, Hosseinzadeh Z, Almilaji A, Lebedeva A, Shumilina E, Alesutan I, Lang F ., PLoS One. January 1, 2014; 9 (1): e87457.
Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. , Thouta S, Sokolov S, Abe Y, Clark SJ, Cheng YM, Claydon TW., Biophys J. March 4, 2014; 106 (5): 1057-69.
Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr. , Martinson AS, van Rossum DB, Diatta FH, Layden MJ, Rhodes SA, Martindale MQ, Jegla T., Proc Natl Acad Sci U S A. April 15, 2014; 111 (15): 5712-7.
Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion. , Ebert AM, Childs SJ, Hehr CL , Cechmanek PB, McFarlane S ., Development. June 1, 2014; 141 (12): 2473-82.
Natural products as potential human ether-a- go-go-related gene channel inhibitors - screening of plant-derived alkaloids. , Schramm A, Saxena P, Chlebek J, Cahlíková L, Baburin I, Hering S, Hamburger M., Planta Med. June 1, 2014; 80 (8-9): 740-6.