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Summary Expression Phenotypes Gene Literature (163) GO Terms (3) Nucleotides (613) Proteins (60) Interactants (996) Wiki
XB-GENEPAGE-966993

Papers associated with gmnn



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In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex., Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J., Proc Natl Acad Sci U S A. June 12, 2012; 109 (24): 9366-71.

Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts., Recolin B, Van der Laan S, Maiorano D., Nucleic Acids Res. April 1, 2012; 40 (8): 3431-42.        

Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells., Oropeza D, Horb M., Genesis. March 1, 2012; 50 (3): 271-85.                        

Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract., Nakaoka H, Nishiyama A, Saito M, Ishikawa F., J Biol Chem. January 2, 2012; 287 (1): 619-627.              

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos., Kisielewska J, Blow JJ., Development. January 1, 2012; 139 (1): 63-74.              

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition., Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ., PLoS One. January 1, 2012; 7 (5): e38009.                        

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks., Hashimoto Y, Puddu F, Costanzo V., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.          

Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair., Peterson SE, Li Y, Chait BT, Gottesman ME, Baer R, Gautier J., J Cell Biol. September 5, 2011; 194 (5): 705-20.              

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication., Kundu LR, Seki M, Watanabe N, Murofushi H, Furukohri A, Waga S, Score AJ, Blow JJ, Horikoshi M, Enomoto T, Tada S., Biochim Biophys Acta. June 1, 2011; 1813 (6): 1129-36.

Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing., Ode KL, Fujimoto K, Kubota Y, Takisawa H., Genes Cells. April 1, 2011; 16 (4): 380-96.

Geminin-deficient neural stem cells exhibit normal cell division and normal neurogenesis., Schultz KM, Banisadr G, Lastra RO, McGuire T, Kessler JA, Miller RJ, McGarry TJ., PLoS One. March 9, 2011; 6 (3): e17736.          

The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module., Rogers CD, Ferzli GS, Casey ES., BMC Dev Biol. January 26, 2011; 11 74.        

DNA is a co-factor for its own replication in Xenopus egg extracts., Lebofsky R, van Oijen AM, Walter JC., Nucleic Acids Res. January 1, 2011; 39 (2): 545-55.            

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo., Lim JW, Hummert P, Mills JC, Kroll KL., Development. January 1, 2011; 138 (1): 33-44.                    

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity., Sasaki T, Li A, Gillespie PJ, Blow JJ, Gilbert DM., Nucleus. January 1, 2011; 2 (5): 455-64.

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction., Fan M, Buraei Z, Luo HR, Levenson-Palmer R, Yang J., Proc Natl Acad Sci U S A. August 17, 2010; 107 (33): 14887-92.

Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila., Herr A, Mckenzie L, Suryadinata R, Sadowski M, Parsons LM, Sarcevic B, Richardson HE., Dev Biol. August 1, 2010; 344 (1): 36-51.

G2 phase chromatin lacks determinants of replication timing., Lu J, Li F, Murphy CS, Davidson MW, Gilbert DM., J Cell Biol. June 14, 2010; 189 (6): 967-80.                

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.        

Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail., Ohe M, Kawamura Y, Ueno H, Inoue D, Kanemori Y, Senoo C, Isoda M, Nakajo N, Sagata N., Mol Biol Cell. March 15, 2010; 21 (6): 905-13.            

Treslin collaborates with TopBP1 in triggering the initiation of DNA replication., Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell. February 5, 2010; 140 (3): 349-59.                        

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels., Thomson AM, Gillespie PJ, Blow JJ., J Cell Biol. January 25, 2010; 188 (2): 209-21.                  

Origin-dependent initiation of DNA replication within telomeric sequences., Kurth I, Gautier J., Nucleic Acids Res. January 1, 2010; 38 (2): 467-76.          

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing., De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 19807-12.

Geminin stabilizes Cdt1 during meiosis in Xenopus oocytes., Narasimhachar Y, Coué M., J Biol Chem. October 2, 2009; 284 (40): 27235-42.

Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation., Yan B, Neilson KM, Moody SA., Dev Dyn. June 1, 2009; 238 (6): 1358-65.        

foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation., Yan B, Neilson KM, Moody SA., Dev Biol. May 1, 2009; 329 (1): 80-95.              

Replication initiation complex formation in the absence of nuclear function in Xenopus., Krasinska L, Fisher D., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.            

Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts., Tsuyama T, Watanabe S, Aoki A, Cho Y, Seki M, Enomoto T, Tada S., Mol Biol Cell. February 1, 2009; 20 (3): 937-47.

Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives., Rogers CD, Harafuji N, Archer T, Cunningham DD, Casey ES., Mech Dev. January 1, 2009; 126 (1-2): 42-55.        

Cloning of Xenopus orthologs of Ctf7/Eco1 acetyltransferase and initial characterization of XEco2., Takagi M, Bunai K, Yanagi K, Imamoto N., FEBS J. December 1, 2008; 275 (24): 6109-22.

DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts., Labit H, Perewoska I, Germe T, Hyrien O, Marheineke K., Nucleic Acids Res. October 1, 2008; 36 (17): 5623-34.              

MCM9 binds Cdt1 and is required for the assembly of prereplication complexes., Lutzmann M, Méchali M., Mol Cell. July 25, 2008; 31 (2): 190-200.

Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition., Khoudoli GA, Gillespie PJ, Stewart G, Andersen JS, Swedlow JR, Blow JJ., Curr Biol. June 3, 2008; 18 (11): 838-43.        

Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.              

Sox3 expression is maintained by FGF signaling and restricted to the neural plate by Vent proteins in the Xenopus embryo., Rogers CD, Archer TC, Cunningham DD, Grammer TC, Casey EM., Dev Biol. January 1, 2008; 313 (1): 307-19.                  

Geminin is cleaved by caspase-3 during apoptosis in Xenopus egg extracts., Auziol C, Méchali M, Maiorano D., Biochem Biophys Res Commun. September 21, 2007; 361 (2): 276-80.

Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, Galloway DA, Gu W, Gautier J, Dalla-Favera R., Nature. July 26, 2007; 448 (7152): 445-51.      

XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms., van Grunsven LA, Taelman V, Michiels C, Verstappen G, Souopgui J, Nichane M, Moens E, Opdecamp K, Vanhomwegen J, Kricha S, Huylebroeck D, Bellefroid EJ., Dev Biol. June 1, 2007; 306 (1): 34-49.            

Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts., Kumata Y, Tada S, Yamanada Y, Tsuyama T, Kobayashi T, Dong YP, Ikegami K, Murofushi H, Seki M, Enomoto T., Biochim Biophys Acta. April 1, 2007; 1773 (4): 556-64.

Geminin prevents rereplication during xenopus development., Kerns SL, Torke SJ, Benjamin JM, McGarry TJ., J Biol Chem. February 23, 2007; 282 (8): 5514-21.

Cdt1 and geminin: role during cell cycle progression and DNA damage in higher eukaryotes., Tada S., Front Biosci. January 1, 2007; 12 1629-41.

Geminin in embryonic development: coordinating transcription and the cell cycle during differentiation., Kroll KL., Front Biosci. January 1, 2007; 12 1395-409.

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus., Lutzmann M, Maiorano D, Méchali M., EMBO J. December 13, 2006; 25 (24): 5764-74.

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision., Davidson IF, Li A, Blow JJ., Mol Cell. November 3, 2006; 24 (3): 433-43.              

De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts., Zembutsu A, Waga S., Nucleic Acids Res. July 26, 2006; 34 (13): e91.          

The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication., Matsuno K, Kumano M, Kubota Y, Hashimoto Y, Takisawa H., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.                

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress., Woodward AM, Göhler T, Luciani MG, Oehlmann M, Ge X, Gartner A, Jackson DA, Blow JJ., J Cell Biol. June 5, 2006; 173 (5): 673-83.              

Subcellular translocation signals regulate Geminin activity during embryonic development., Boos A, Lee A, Thompson DM, Kroll KL., Biol Cell. June 1, 2006; 98 (6): 363-75.

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