Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (163) GO Terms (3) Nucleotides (613) Proteins (60) Interactants (996) Wiki
XB-GENEPAGE-966993

Papers associated with gmnn



???displayGene.coCitedPapers???

???pagination.result.count???

???pagination.result.page??? ???pagination.result.prev??? 1 2 3 4 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts., Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.

Regulation of replication licensing by acetyltransferase Hbo1., Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.

Tcf- and Vent-binding sites regulate neural-specific geminin expression in the gastrula embryo., Taylor JJ, Wang T, Kroll KL., Dev Biol. January 15, 2006; 289 (2): 494-506.                

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts., Leach CA, Michael WM., J Cell Biol. December 19, 2005; 171 (6): 947-54.                

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity., Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL., Genes Dev. July 15, 2005; 19 (14): 1723-34.      

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development., Yanagi K, Mizuno T, Tsuyama T, Tada S, Iida Y, Sugimoto A, Eki T, Enomoto T, Hanaoka F., J Biol Chem. May 20, 2005; 280 (20): 19689-94.

BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation., Tao J, Kuliyev E, Wang X, Li X, Wilanowski T, Jane SM, Mead PE, Cunningham JM., Development. March 1, 2005; 132 (5): 1021-34.        

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., Maiorano D, Krasinska L, Lutzmann M, Mechali M., Curr Biol. January 26, 2005; 15 (2): 146-53.

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus., Li A, Blow JJ., EMBO J. January 26, 2005; 24 (2): 395-404.

Functional domains of the Xenopus replication licensing factor Cdt1., Ferenbach A, Li A, Brito-Martins M, Blow JJ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.              

Systematic screening for genes specifically expressed in the anterior neuroectoderm during early Xenopus development., Takahashi N, Tochimoto N, Ohmori SY, Mamada H, Itoh M, Inamori M, Shinga J, Osada S, Taira M., Int J Dev Biol. January 1, 2005; 49 (8): 939-51.                                    

Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs., Yoshida K, Takisawa H, Kubota Y., Genes Cells. January 1, 2005; 10 (1): 63-73.

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts., Arias EE, Walter JC., Genes Dev. January 1, 2005; 19 (1): 114-26.

Measurement of geminin activity in Xenopus egg extracts., McGarry TJ., Methods Mol Biol. January 1, 2005; 296 263-78.

DNA replication licensing in somatic and germ cells., Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity., Benjamin JM, Torke SJ, Demeler B, McGarry TJ., J Biol Chem. October 29, 2004; 279 (44): 45957-68.

Regulation of early events in chromosome replication., Diffley JF., Curr Biol. September 21, 2004; 14 (18): R778-86.

Scc2 couples replication licensing to sister chromatid cohesion in Xenopus egg extracts., Gillespie PJ, Hirano T., Curr Biol. September 7, 2004; 14 (17): 1598-603.

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin., Lee C, Lee C, Hong B, Choi JM, Kim Y, Watanabe S, Ishimi Y, Enomoto T, Tada S, Kim Y, Cho Y., Nature. August 19, 2004; 430 (7002): 913-7.

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis., Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K., EMBO J. August 4, 2004; 23 (15): 3122-32.

Geminin: a major DNA replication safeguard in higher eukaryotes., Melixetian M, Helin K., Cell Cycle. August 1, 2004; 3 (8): 1002-4.

A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition., Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, Kornbluth S, Swaminathan K, Dutta A., Mol Cell. July 23, 2004; 15 (2): 245-58.

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication., Jares P, Luciani MG, Blow JJ., BMC Mol Biol. June 28, 2004; 5 5.          

Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases., Li W, Kim SM, Lee J, Lee J, Dunphy WG., J Cell Biol. June 21, 2004; 165 (6): 801-12.                

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation., Oehlmann M, Score AJ, Blow JJ., J Cell Biol. April 26, 2004; 165 (2): 181-90.                  

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis., Maiorano D, Rul W, Méchali M., Exp Cell Res. April 15, 2004; 295 (1): 138-49.

Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing., Li A, Blow JJ., Cell Cycle. April 1, 2004; 3 (4): 443-5.

Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination., Li A, Blow JJ., Nat Cell Biol. March 1, 2004; 6 (3): 260-7.

Direct interaction of geminin and Six3 in eye development., Del Bene F, Tessmar-Raible K, Wittbrodt J., Nature. February 19, 2004; 427 (6976): 745-9.

Spatial distribution and specification of mammalian replication origins during G1 phase., Li F, Chen J, Solessio E, Gilbert DM., J Cell Biol. April 28, 2003; 161 (2): 257-66.            

A role of topoisomerase II in linking DNA replication to chromosome condensation., Cuvier O, Hirano T., J Cell Biol. March 3, 2003; 160 (5): 645-55.              

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication., Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.          

Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus., McGarry TJ., Mol Biol Cell. October 1, 2002; 13 (10): 3662-71.            

Crystallization and preliminary X-ray crystallographic analysis of human Geminin coiled-coil domain., Thépaut M, Hoh F, Dumas C, Calas B, Strub MP, Padilla A., Biochim Biophys Acta. September 23, 2002; 1599 (1-2): 149-51.

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts., Stokes MP, Van Hatten R, Lindsay HD, Michael WM., J Cell Biol. September 2, 2002; 158 (5): 863-72.        

Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract., Kobayashi T, Tada S, Tsuyama T, Murofushi H, Seki M, Enomoto T., J Cell Sci. August 1, 2002; 115 (Pt 15): 3159-69.

Molecular cloning and characterization of dullard: a novel gene required for neural development., Satow R, Chan TC, Asashima M., Biochem Biophys Res Commun. July 5, 2002; 295 (1): 85-91.                  

Expression of geminin as a marker of cell proliferation in normal tissues and malignancies., Wohlschlegel JA, Kutok JL, Weng AP, Dutta A., Am J Pathol. July 1, 2002; 161 (1): 267-73.

Control of DNA replication licensing in a cell cycle., Nishitani H, Lygerou Z., Genes Cells. June 1, 2002; 7 (6): 523-34.        

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import., Hodgson B, Li A, Tada S, Blow JJ., Curr Biol. April 16, 2002; 12 (8): 678-83.

Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin., Sun WH, Coleman TR, DePamphilis ML., EMBO J. March 15, 2002; 21 (6): 1437-46.

Mammalian nuclei become licensed for DNA replication during late telophase., Dimitrova DS, Prokhorova TA, Blow JJ, Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase., Nishitani H, Taraviras S, Lygerou Z, Nishimoto T., J Biol Chem. November 30, 2001; 276 (48): 44905-11.

Neural induction takes a transcriptional twist., Bainter JJ, Boos A, Kroll KL., Dev Dyn. November 1, 2001; 222 (3): 315-27.  

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis., Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.    

Triggering ubiquitination of a CDK inhibitor at origins of DNA replication., Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK., Nat Cell Biol. August 1, 2001; 3 (8): 715-22.

Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle., Okuno Y, McNairn AJ, den Elzen N, Pines J, Gilbert DM., EMBO J. August 1, 2001; 20 (15): 4263-77.

Microarray-based analysis of early development in Xenopus laevis., Altmann CR, Bell E, Sczyrba A, Pun J, Bekiranov S, Gaasterland T, Brivanlou AH., Dev Biol. August 1, 2001; 236 (1): 64-75.            

???pagination.result.page??? ???pagination.result.prev??? 1 2 3 4 ???pagination.result.next???