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Geminin, an inhibitor of DNA replication, is degraded during mitosis. , McGarry TJ, Kirschner MW ., Cell. June 12, 1998; 93 (6): 1043-53.
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation. , Kroll KL , Salic AN, Evans LM, Kirschner MW ., Development. August 1, 1998; 125 (16): 3247-58.
Regulation of dorsal gene expression in Xenopus by the ventralizing homeodomain gene Vox. , Melby AE, Clements WK, Kimelman D ., Dev Biol. July 15, 1999; 211 (2): 293-305.
Cell cycle-regulated proteolysis of mitotic target proteins. , Bastians H, Topper LM, Gorbsky GL , Ruderman JV ., Mol Biol Cell. November 1, 1999; 10 (11): 3927-41.
Xbra3 induces mesoderm and neural tissue in Xenopus laevis. , Strong CF, Barnett MW, Hartman D, Jones EA , Stott D., Dev Biol. June 15, 2000; 222 (2): 405-19.
Imaging patterns of calcium transients during neural induction in Xenopus laevis embryos. , Leclerc C , Webb SE, Daguzan C, Moreau M , Miller AL ., J Cell Sci. October 1, 2000; 113 Pt 19 3519-29.
Cell cycle. License withheld-- geminin blocks DNA replication. , Lygerou Z, Nurse P., Science. December 22, 2000; 290 (5500): 2271-3.
Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. , Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC , Dutta A ., Science. December 22, 2000; 290 (5500): 2309-12.
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. , Gillespie PJ, Li A, Blow JJ ., BMC Biochem. January 1, 2001; 2 15.
Geminin bans replication licence. , Madine M, Laskey R., Nat Cell Biol. February 1, 2001; 3 (2): E49-50.
Repression of origin assembly in metaphase depends on inhibition of RLF-B/ Cdt1 by geminin. , Tada S, Li A, Maiorano D , Méchali M, Blow JJ ., Nat Cell Biol. February 1, 2001; 3 (2): 107-13.
foxD5a, a Xenopus winged helix gene, maintains an immature neural ectoderm via transcriptional repression that is dependent on the C-terminal domain. , Sullivan SA, Akers L, Moody SA ., Dev Biol. April 15, 2001; 232 (2): 439-57.
Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/ Gem. , Béguin P, Nagashima K, Gonoi T, Shibasaki T, Takahashi K, Kashima Y, Ozaki N, Geering K, Iwanaga T, Seino S., Nature. June 7, 2001; 411 (6838): 701-6.
Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. , Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK ., Nat Cell Biol. August 1, 2001; 3 (8): 715-22.
Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle. , Okuno Y, McNairn AJ, den Elzen N, Pines J, Gilbert DM., EMBO J. August 1, 2001; 20 (15): 4263-77.
Microarray-based analysis of early development in Xenopus laevis. , Altmann CR , Bell E , Sczyrba A, Pun J, Bekiranov S, Gaasterland T, Brivanlou AH ., Dev Biol. August 1, 2001; 236 (1): 64-75.
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis. , Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.
Neural induction takes a transcriptional twist. , Bainter JJ, Boos A, Kroll KL ., Dev Dyn. November 1, 2001; 222 (3): 315-27.
The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase. , Nishitani H, Taraviras S, Lygerou Z, Nishimoto T., J Biol Chem. November 30, 2001; 276 (48): 44905-11.
Mammalian nuclei become licensed for DNA replication during late telophase. , Dimitrova DS, Prokhorova TA, Blow JJ , Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.
Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin. , Sun WH, Coleman TR , DePamphilis ML., EMBO J. March 15, 2002; 21 (6): 1437-46.
Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. , Hodgson B, Li A, Tada S, Blow JJ ., Curr Biol. April 16, 2002; 12 (8): 678-83.
Control of DNA replication licensing in a cell cycle. , Nishitani H, Lygerou Z., Genes Cells. June 1, 2002; 7 (6): 523-34.
Expression of geminin as a marker of cell proliferation in normal tissues and malignancies. , Wohlschlegel JA, Kutok JL, Weng AP, Dutta A ., Am J Pathol. July 1, 2002; 161 (1): 267-73.
Molecular cloning and characterization of dullard: a novel gene required for neural development. , Satow R, Chan TC , Asashima M ., Biochem Biophys Res Commun. July 5, 2002; 295 (1): 85-91.
Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract. , Kobayashi T, Tada S, Tsuyama T, Murofushi H, Seki M, Enomoto T., J Cell Sci. August 1, 2002; 115 (Pt 15): 3159-69.
DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. , Stokes MP, Van Hatten R, Lindsay HD , Michael WM., J Cell Biol. September 2, 2002; 158 (5): 863-72.
Crystallization and preliminary X-ray crystallographic analysis of human Geminin coiled-coil domain. , Thépaut M, Hoh F, Dumas C, Calas B, Strub MP, Padilla A., Biochim Biophys Acta. September 23, 2002; 1599 (1-2): 149-51.
Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus. , McGarry TJ., Mol Biol Cell. October 1, 2002; 13 (10): 3662-71.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC , Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.
A role of topoisomerase II in linking DNA replication to chromosome condensation. , Cuvier O, Hirano T., J Cell Biol. March 3, 2003; 160 (5): 645-55.
Spatial distribution and specification of mammalian replication origins during G1 phase. , Li F, Chen J , Solessio E, Gilbert DM., J Cell Biol. April 28, 2003; 161 (2): 257-66.
Direct interaction of geminin and Six3 in eye development. , Del Bene F, Tessmar-Raible K, Wittbrodt J ., Nature. February 19, 2004; 427 (6976): 745-9.
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination. , Li A, Blow JJ ., Nat Cell Biol. March 1, 2004; 6 (3): 260-7.
Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing. , Li A, Blow JJ ., Cell Cycle. April 1, 2004; 3 (4): 443-5.
Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis. , Maiorano D , Rul W, Méchali M., Exp Cell Res. April 15, 2004; 295 (1): 138-49.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M, Score AJ, Blow JJ ., J Cell Biol. April 26, 2004; 165 (2): 181-90.
Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases. , Li W , Kim SM, Lee J , Lee J , Dunphy WG ., J Cell Biol. June 21, 2004; 165 (6): 801-12.
A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication. , Jares P, Luciani MG, Blow JJ ., BMC Mol Biol. June 28, 2004; 5 5.
A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. , Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, Kornbluth S , Swaminathan K, Dutta A ., Mol Cell. July 23, 2004; 15 (2): 245-58.
Geminin: a major DNA replication safeguard in higher eukaryotes. , Melixetian M, Helin K., Cell Cycle. August 1, 2004; 3 (8): 1002-4.
Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis. , Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K., EMBO J. August 4, 2004; 23 (15): 3122-32.
Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. , Lee C , Lee C , Hong B, Choi JM, Kim Y, Watanabe S, Ishimi Y, Enomoto T, Tada S, Kim Y, Cho Y., Nature. August 19, 2004; 430 (7002): 913-7.
Scc2 couples replication licensing to sister chromatid cohesion in Xenopus egg extracts. , Gillespie PJ, Hirano T., Curr Biol. September 7, 2004; 14 (17): 1598-603.
Regulation of early events in chromosome replication. , Diffley JF., Curr Biol. September 21, 2004; 14 (18): R778-86.
Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. , Benjamin JM, Torke SJ, Demeler B, McGarry TJ., J Biol Chem. October 29, 2004; 279 (44): 45957-68.
DNA replication licensing in somatic and germ cells. , Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI , Prevost AT, Blow JJ , Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.
Systematic screening for genes specifically expressed in the anterior neuroectoderm during early Xenopus development. , Takahashi N, Tochimoto N, Ohmori SY, Mamada H, Itoh M, Inamori M, Shinga J, Osada S, Taira M ., Int J Dev Biol. January 1, 2005; 49 (8): 939-51.
Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs. , Yoshida K, Takisawa H, Kubota Y., Genes Cells. January 1, 2005; 10 (1): 63-73.
Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. , Arias EE, Walter JC ., Genes Dev. January 1, 2005; 19 (1): 114-26.