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Summary Expression Phenotypes Gene Literature (78) GO Terms (14) Nucleotides (227) Proteins (56) Interactants (303) Wiki
XB-GENEPAGE-999034

Papers associated with furin



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Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition., Sheng S, Carattino MD, Bruns JB, Hughey RP, Kleyman TR., Am J Physiol Renal Physiol. June 1, 2006; 290 (6): F1488-96.

Emilin1 links TGF-beta maturation to blood pressure homeostasis., Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S, Cifelli G, Ferrari A, Maffei A, Fabbro C, Braghetta P, Marino G, Selvetella G, Aretini A, Colonnese C, Bettarini U, Russo G, Soligo S, Adorno M, Bonaldo P, Volpin D, Piccolo S, Lembo G, Bressan GM., Cell. March 10, 2006; 124 (5): 929-42.    

Proprotein convertase genes in Xenopus development., Nelsen S, Berg L, Wong C, Christian JL., Dev Dyn. July 1, 2005; 233 (3): 1038-44.    

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development., Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J., Development. February 1, 2005; 132 (3): 591-602.                      

Distinct pools of epithelial sodium channels are expressed at the plasma membrane., Hughey RP, Bruns JB, Kinlough CL, Kleyman TR., J Biol Chem. November 19, 2004; 279 (47): 48491-4.

Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4., Degnin C, Jean F, Thomas G, Christian JL., Mol Biol Cell. November 1, 2004; 15 (11): 5012-20.

Proteolytic enzymes and altered glycosylation modulate dystroglycan function in carcinoma cells., Singh J, Itahana Y, Knight-Krajewski S, Kanagawa M, Campbell KP, Bissell MJ, Muschler J., Cancer Res. September 1, 2004; 64 (17): 6152-9.

Epithelial sodium channels are activated by furin-dependent proteolysis., Hughey RP, Bruns JB, Kinlough CL, Harkleroad KL, Tong Q, Carattino MD, Johnson JP, Stockand JD, Kleyman TR., J Biol Chem. April 30, 2004; 279 (18): 18111-4.

The structure and regulation of the human and mouse matrix metalloproteinase-21 gene and protein., Marchenko GN, Marchenko ND, Strongin AY., Biochem J. June 1, 2003; 372 (Pt 2): 503-15.

Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer., Ahokas K, Lohi J, Lohi H, Elomaa O, Karjalainen-Lindsberg ML, Kere J, Saarialho-Kere U., Gene. November 13, 2002; 301 (1-2): 31-41.

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor., Cui Y, Hackenmiller R, Berg L, Jean F, Nakayama T, Thomas G, Christian JL., Genes Dev. November 1, 2001; 15 (21): 2797-802.

A hatching enzyme substrate in the Xenopus laevis egg envelope is a high molecular weight ZPA homolog., Lindsay LL, Wallace MA, Hedrick JL., Dev Growth Differ. June 1, 2001; 43 (3): 305-13.            

Primary structure and developmental expression of Dp ZP2, a vitelline envelope glycoprotein homolog of mouse ZP2, in Discoglossus pictus, one of the oldest living Anuran species., Vaccaro MC, Santo MG, Caputo M, Just M, Tian JD, Gong H, Lennarz WJ, Campanella C., Mol Reprod Dev. June 1, 2001; 59 (2): 133-43.

Egg envelope glycoprotein gp37 as a Xenopus homolog of mammalian ZP1, based on cDNA cloning., Kubo H, Kawano T, Tsubuki S, Kotani M, Kawasaki H, Kawashima S., Dev Growth Differ. August 1, 2000; 42 (4): 419-27.        

Comparison of ZP3 protein sequences among vertebrate species: to obtain a consensus sequence for immunocontraception., Zhu X, Naz RK., Front Biosci. March 1, 1999; 4 D212-5.

Xenopus laevis sperm receptor gp69/64 glycoprotein is a homolog of the mammalian sperm receptor ZP2., Tian J, Gong H, Lennarz WJ., Proc Natl Acad Sci U S A. February 2, 1999; 96 (3): 829-34.        

Isolation and characterisation of a cDNA encoding a zona pellucida protein (ZPB) from the marsupial Trichosurus vulpecula (brushtail possum)., Haines BP, Rathjen PD, Hope RM, Whyatt LM, Holland MK, Breed WG., Mol Reprod Dev. February 1, 1999; 52 (2): 174-82.

Molecular basis for oviductin-mediated processing from gp43 to gp41, the predominant glycoproteins of Xenopus egg envelopes., Kubo H, Matsushita M, Kotani M, Kawasaki H, Saido TC, Kawashima S, Katagiri C, Suzuki A., Dev Genet. January 1, 1999; 25 (2): 123-9.      

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin., Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ, Constam DB., Development. December 1, 1998; 125 (24): 4863-76.

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development., Cui Y, Jean F, Thomas G, Christian JL., EMBO J. August 17, 1998; 17 (16): 4735-43.

cDNA cloning and sequence analysis of the Xenopus laevis egg envelope glycoprotein gp43., Yang JC, Hedrick JL., Dev Growth Differ. August 1, 1997; 39 (4): 457-67.        

A novel matrix metalloproteinase gene (XMMP) encoding vitronectin-like motifs is transiently expressed in Xenopus laevis early embryo development., Yang M, Murray MT, Kurkinen M., J Biol Chem. May 23, 1997; 272 (21): 13527-33.          

Rat stromelysin 3: cDNA cloning from healing skin wound, activation by furin and expression in rat tissues., Okada A, Saez S, Misumi Y, Basset P., Gene. February 7, 1997; 185 (2): 187-93.

Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2., Badman MK, Shennan KI, Jermany JL, Docherty K, Clark A., FEBS Lett. January 15, 1996; 378 (3): 227-31.

Cloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular region., Jiang YP, Wang H, D'Eustachio P, Musacchio JM, Schlessinger J, Sap J., Mol Cell Biol. May 1, 1993; 13 (5): 2942-51.

Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases., Van de Ven WJ, Roebroek AJ, Van Duijnhoven HL., Crit Rev Oncog. January 1, 1993; 4 (2): 115-36.

Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes., Korner J, Chun J, O'Bryan L, Axel R., Proc Natl Acad Sci U S A. December 15, 1991; 88 (24): 11393-7.

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