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Summary Expression Phenotypes Gene Literature (134) GO Terms (21) Nucleotides (172) Proteins (52) Interactants (310) Wiki
XB-GENEPAGE-985622

Papers associated with dtl



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Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome., Sánchez HA, Mese G, Srinivas M, White TW, Verselis VK., J Gen Physiol. July 1, 2010; 136 (1): 47-62.                  

Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other., Ambrosi C, Gassmann O, Pranskevich JN, Boassa D, Smock A, Wang J, Dahl G, Steinem C, Sosinsky GE., J Biol Chem. August 6, 2010; 285 (32): 24420-31.                    

The CRL4Cdt2 ubiquitin ligase mediates the proteolysis of cyclin-dependent kinase inhibitor Xic1 through a direct association with PCNA., Kim DH, Budhavarapu VN, Herrera CR, Nam HW, Kim YS, Yew PR., Mol Cell Biol. September 1, 2010; 30 (17): 4120-33.

CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase., Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L., Mol Cell. October 8, 2010; 40 (1): 22-33.

A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons., Park JY, Remy S, Varela J, Cooper DC, Chung S, Kang HW, Lee JH, Spruston N., PLoS Biol. November 16, 2010; 8 (11): e1000534.                    

Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis., Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H., Genes Cells. January 1, 2011; 16 (1): 12-22.        

Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase., Havens CG, Walter JC., Genes Dev. August 1, 2011; 25 (15): 1568-82.

TRPM7 is required within zebrafish sensory neurons for the activation of touch-evoked escape behaviors., Low SE, Amburgey K, Horstick E, Linsley J, Sprague SM, Cui WW, Zhou W, Hirata H, Saint-Amant L, Hume RI, Kuwada JY., J Neurosci. August 10, 2011; 31 (32): 11633-44.                  

5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals., McKinnon NK, Reeves DC, Akabas MH., J Gen Physiol. October 1, 2011; 138 (4): 453-66.                

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction., Raman M, Havens CG, Walter JC, Harper JW., Mol Cell. October 7, 2011; 44 (1): 72-84.

Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics., Kwon T, Harris AL, Rossi A, Bargiello TA., J Gen Physiol. November 1, 2011; 138 (5): 475-93.            

Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes., Maksaev G, Haswell ES., J Gen Physiol. December 1, 2011; 138 (6): 641-9.        

Covalent modification of mutant rat P2X2 receptors with a thiol-reactive fluorophore allows channel activation by zinc or acidic pH without ATP., Dellal SS, Hume RI., PLoS One. January 1, 2012; 7 (10): e47147.                    

Infrared light excites cells by changing their electrical capacitance., Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F., Nat Commun. March 13, 2012; 3 736.          

Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2., Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC., J Biol Chem. March 30, 2012; 287 (14): 11410-21.

Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2., Blanchard MG, Rash LD, Kellenberger S., Br J Pharmacol. April 1, 2012; 165 (7): 2167-77.

Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains., Bagriantsev SN, Clark KA, Minor DL., EMBO J. August 1, 2012; 31 (15): 3297-308.            

The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK., Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H., Front Pharmacol. January 1, 2013; 4 141.              

Cargo transport by cytoplasmic Dynein can center embryonic centrosomes., Longoria RA, Shubeita GT., PLoS One. January 1, 2013; 8 (7): e67710.            

The eag domain regulates hERG channel inactivation gating via a direct interaction., Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.                  

Molecular mechanism of voltage sensing in voltage-gated proton channels., Gonzalez C, Rebolledo S, Perez ME, Larsson HP., J Gen Physiol. March 1, 2013; 141 (3): 275-85.              

Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation., Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR, Yew PR., Cell Div. April 22, 2013; 8 (1): 5.              

2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2)., Beltrán L, Beltrán M, Aguado A, Gisselmann G, Hatt H., Front Pharmacol. May 15, 2013; 4 63.      

Biomechanics and the thermotolerance of development., von Dassow M, Miller CJ, Davidson LA., PLoS One. January 1, 2014; 9 (4): e95670.            

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR., Cui G, Rahman KS, Infield DT, Kuang C, Prince CZ, McCarty NA., J Gen Physiol. August 1, 2014; 144 (2): 159-79.                          

Thymine DNA glycosylase is a CRL4Cdt2 substrate., Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.

Ion conduction and selectivity in acid-sensing ion channel 1., Yang L, Palmer LG., J Gen Physiol. September 1, 2014; 144 (3): 245-55.                              

Intracellular ATP does not inhibit Slo2.1 K+ channels., Garg P, Sanguinetti MC., Physiol Rep. September 11, 2014; 2 (9):         

Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries., Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL., ACS Chem Neurosci. September 17, 2014; 5 (9): 812-22.              

A novel PKD2L1 C-terminal domain critical for trimerization and channel function., Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Cao Y, Zeng H, Tang J, Chen XZ., Sci Rep. January 12, 2015; 5 9460.              

Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling., Kollert S, Dombert B, Döring F, Wischmeyer E., Sci Rep. January 12, 2015; 5 12548.            

Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca(2.)., Hussein S, Zheng W, Dyte C, Wang Q, Yang J, Zhang F, Tang J, Cao Y, Cao Y, Chen XZ., Sci Rep. January 12, 2015; 5 15752.                  

Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels., Chang HK, Iwamoto M, Oiki S, Shieh RC., Sci Rep. January 12, 2015; 5 18404.              

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus., Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK., PLoS Genet. March 10, 2015; 11 (3): e1005018.                              

Transient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel., Badheka D, Borbiro I, Rohacs T., J Gen Physiol. July 1, 2015; 146 (1): 65-77.                

Phase transition of spindle-associated protein regulate spindle apparatus assembly., Jiang H, Wang S, Huang Y, He X, Cui H, Zhu X, Zheng Y., Cell. September 24, 2015; 163 (1): 108-22.              

Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels., Goldstein M, Rinné S, Kiper AK, Ramírez D, Netter MF, Bustos D, Ortiz-Bonnin B, González W, Decher N., Sci Rep. January 22, 2016; 6 19492.              

A novel synaptic plasticity rule explains homeostasis of neuromuscular transmission., Ouanounou G, Baux G, Bal T., Elife. May 3, 2016; 5                                 

Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states., McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ., J Gen Physiol. June 1, 2016; 147 (6): 497-505.          

Xenopus Oocyte As a Model System to Study Store-Operated Ca(2+) Entry (SOCE)., Courjaret R, Machaca K., Front Cell Dev Biol. June 24, 2016; 4 66.              

Structural rearrangement of the intracellular domains during AMPA receptor activation., Zachariassen LG, Katchan L, Jensen AG, Pickering DS, Plested AJ, Kristensen AS., Proc Natl Acad Sci U S A. July 5, 2016; 113 (27): E3950-9.                            

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel., Upadhyay A, Pisupati A, Jegla T, Crook M, Mickolajczyk KJ, Shorey M, Rohan LE, Billings KA, Rolls MM, Hancock WO, Hanna-Rose W., Nat Commun. October 12, 2016; 7 13135.                

Mechanosensory Stimulation Evokes Acute Concussion-Like Behavior by Activating GIRKs Coupled to Muscarinic Receptors in a Simple Vertebrate., Li WC, Zhu XY, Ritson E., eNeuro. January 1, 2017; 4 (2):                   

Identification of Key Residues for Urate Specific Transport in Human Glucose Transporter 9 (hSLC2A9)., Long W, Panigrahi R, Panwar P, Wong K, O Neill D, Chen XZ, Lemieux MJ, Cheeseman CI., Sci Rep. January 24, 2017; 7 41167.                

A selectivity filter at the intracellular end of the acid-sensing ion channel pore., Lynagh T, Flood E, Boiteux C, Wulf M, Komnatnyy VV, Colding JM, Allen TW, Pless SA., Elife. May 12, 2017; 6                   

The Effect of Pungent and Tingling Compounds from Piper nigrum L. on Background K+ Currents., Beltrán LR, Dawid C, Beltrán M, Levermann J, Titt S, Thomas S, Pürschel V, Satalik M, Gisselmann G, Hofmann T, Hatt H., Front Pharmacol. May 26, 2017; 8 408.                

GABA-B Controls Persistent Na+ Current and Coupled Na+-Activated K+ Current., Li P, Stewart R, Butler A, Gonzalez-Cota AL, Harmon S, Salkoff L., eNeuro. June 12, 2017; 4 (3):         

The modulation of two motor behaviors by persistent sodium currents in Xenopus laevis tadpoles., Svensson E, Jeffreys H, Li WC., J Neurophysiol. July 1, 2017; 118 (1): 121-130.        

Expression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis., Velisetty P, Stein RA, Sierra-Valdez FJ, Vásquez V, Cordero-Morales JF., Sci Rep. August 29, 2017; 7 (1): 9861.                

The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool., Mishra A, Salari A, Berigan BR, Miguel KC, Amirshenava M, Robinson A, Zars BC, Lin JL, Milescu LS, Milescu M, Zars T., Sci Rep. January 17, 2018; 8 (1): 901.      

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