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The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. , Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK ., PLoS Genet. March 10, 2015; 11 (3): e1005018.
A novel PKD2L1 C-terminal domain critical for trimerization and channel function. , Zheng W, Hussein S, Yang J , Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y , Cao Y , Zeng H, Tang J, Chen XZ., Sci Rep. January 12, 2015; 5 9460.
Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling. , Kollert S, Dombert B, Döring F, Wischmeyer E., Sci Rep. January 12, 2015; 5 12548.
Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca(2.). , Hussein S, Zheng W, Dyte C, Wang Q, Yang J , Zhang F, Tang J, Cao Y , Cao Y , Chen XZ., Sci Rep. January 12, 2015; 5 15752.
Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels. , Chang HK, Iwamoto M, Oiki S, Shieh RC., Sci Rep. January 12, 2015; 5 18404.
Tethered protein display identifies a novel Kir3.2 ( GIRK2) regulator from protein scaffold libraries. , Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL., ACS Chem Neurosci. September 17, 2014; 5 (9): 812-22.
Intracellular ATP does not inhibit Slo2.1 K+ channels. , Garg P, Sanguinetti MC., Physiol Rep. September 11, 2014; 2 (9):
Ion conduction and selectivity in acid-sensing ion channel 1. , Yang L, Palmer LG., J Gen Physiol. September 1, 2014; 144 (3): 245-55.
Thymine DNA glycosylase is a CRL4Cdt2 substrate. , Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC ., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.
Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR. , Cui G, Rahman KS, Infield DT, Kuang C, Prince CZ, McCarty NA., J Gen Physiol. August 1, 2014; 144 (2): 159-79.
Biomechanics and the thermotolerance of development. , von Dassow M, Miller CJ, Davidson LA ., PLoS One. January 1, 2014; 9 (4): e95670.
2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 ( TREK-1), KCNK 4 ( TRAAK), and KCNK 10 ( TREK-2). , Beltrán L, Beltrán M, Aguado A, Gisselmann G, Hatt H., Front Pharmacol. May 15, 2013; 4 63.
Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation. , Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR , Yew PR., Cell Div. April 22, 2013; 8 (1): 5.
Molecular mechanism of voltage sensing in voltage-gated proton channels. , Gonzalez C, Rebolledo S, Perez ME, Larsson HP., J Gen Physiol. March 1, 2013; 141 (3): 275-85.
The eag domain regulates hERG channel inactivation gating via a direct interaction. , Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.
The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK. , Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H., Front Pharmacol. January 1, 2013; 4 141.
Cargo transport by cytoplasmic Dynein can center embryonic centrosomes. , Longoria RA, Shubeita GT., PLoS One. January 1, 2013; 8 (7): e67710.
Metabolic and thermal stimuli control K(2P)2.1 ( TREK-1) through modular sensory and gating domains. , Bagriantsev SN, Clark KA, Minor DL., EMBO J. August 1, 2012; 31 (15): 3297-308.
Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2. , Blanchard MG, Rash LD, Kellenberger S., Br J Pharmacol. April 1, 2012; 165 (7): 2167-77.
Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2. , Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC ., J Biol Chem. March 30, 2012; 287 (14): 11410-21.
Infrared light excites cells by changing their electrical capacitance. , Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F., Nat Commun. March 13, 2012; 3 736.
Covalent modification of mutant rat P2X2 receptors with a thiol-reactive fluorophore allows channel activation by zinc or acidic pH without ATP. , Dellal SS, Hume RI., PLoS One. January 1, 2012; 7 (10): e47147.
Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes. , Maksaev G, Haswell ES., J Gen Physiol. December 1, 2011; 138 (6): 641-9.
Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics. , Kwon T , Harris AL, Rossi A, Bargiello TA., J Gen Physiol. November 1, 2011; 138 (5): 475-93.
A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. , Raman M, Havens CG, Walter JC , Harper JW., Mol Cell. October 7, 2011; 44 (1): 72-84.
5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals. , McKinnon NK, Reeves DC, Akabas MH., J Gen Physiol. October 1, 2011; 138 (4): 453-66.
TRPM7 is required within zebrafish sensory neurons for the activation of touch-evoked escape behaviors. , Low SE, Amburgey K, Horstick E, Linsley J, Sprague SM, Cui WW, Zhou W, Hirata H, Saint-Amant L, Hume RI, Kuwada JY., J Neurosci. August 10, 2011; 31 (32): 11633-44.
Mechanism of CRL4( Cdt2), a PCNA-dependent E3 ubiquitin ligase. , Havens CG, Walter JC ., Genes Dev. August 1, 2011; 25 (15): 1568-82.
Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4( Cdt2) -mediated proteolysis. , Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H., Genes Cells. January 1, 2011; 16 (1): 12-22.
A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons. , Park JY , Remy S, Varela J, Cooper DC, Chung S, Kang HW, Lee JH , Spruston N., PLoS Biol. November 16, 2010; 8 (11): e1000534.
CRL4( Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. , Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC , Zou L., Mol Cell. October 8, 2010; 40 (1): 22-33.
The CRL4Cdt2 ubiquitin ligase mediates the proteolysis of cyclin-dependent kinase inhibitor Xic1 through a direct association with PCNA. , Kim DH, Budhavarapu VN, Herrera CR, Nam HW, Kim YS, Yew PR., Mol Cell Biol. September 1, 2010; 30 (17): 4120-33.
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. , Ambrosi C, Gassmann O, Pranskevich JN, Boassa D, Smock A, Wang J , Dahl G, Steinem C, Sosinsky GE., J Biol Chem. August 6, 2010; 285 (32): 24420-31.
Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome. , Sánchez HA, Mese G, Srinivas M, White TW, Verselis VK., J Gen Physiol. July 1, 2010; 136 (1): 47-62.
An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors. , Stürzebecher AS, Hu J, Smith ES, Frahm S, Santos-Torres J, Kampfrath B, Auer S, Lewin GR, Ibañez-Tallon I., J Physiol. May 15, 2010; 588 (Pt 10): 1695-707.
The N terminus of monoamine transporters is a lever required for the action of amphetamines. , Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH., J Biol Chem. April 2, 2010; 285 (14): 10924-38.
Activation of Slo2.1 channels by niflumic acid. , Dai L, Garg V, Sanguinetti MC., J Gen Physiol. March 1, 2010; 135 (3): 275-95.
Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics. , Larsen AP, Olesen SP., PLoS One. February 2, 2010; 5 (2): e9021.
Functional characterization of intracellular Dictyostelium discoideum P2X receptors. , Ludlow MJ, Durai L, Ennion SJ., J Biol Chem. December 11, 2009; 284 (50): 35227-39.
The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line. , Swayne LA, Mezghrani A, Varrault A, Chemin J, Bertrand G, Dalle S, Bourinet E, Lory P, Miller RJ, Nargeot J, Monteil A., EMBO Rep. August 1, 2009; 10 (8): 873-80.
Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels. , Nagatomo K, Kubo Y., Proc Natl Acad Sci U S A. November 11, 2008; 105 (45): 17373-8.
Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating. , Verselis VK, Srinivas M., J Gen Physiol. September 1, 2008; 132 (3): 315-27.
Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition. , Chan KW, Wheeler A, Csanády L., J Gen Physiol. January 1, 2008; 131 (1): 43-58.
Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity. , Wotring VE, Weiss DS., J Gen Physiol. January 1, 2008; 131 (1): 87-97.
Organization of the pronephric kidney revealed by large-scale gene expression mapping. , Raciti D , Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW ., Genome Biol. January 1, 2008; 9 (5): R84.
A combined patch-clamp and electrorotation study of the voltage- and frequency-dependent membrane capacitance caused by structurally dissimilar lipophilic anions. , Zimmermann D, Kiesel M, Terpitz U, Zhou A, Reuss R, Kraus J, Schenk WA, Bamberg E, Sukhorukov VL., J Membr Biol. January 1, 2008; 221 (2): 107-21.
State-dependent block of BK channels by synthesized shaker ball peptides. , Li W , Aldrich RW., J Gen Physiol. October 1, 2006; 128 (4): 423-41.
A family of diverse Cul4- Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. , Jin J, Arias EE, Chen J , Harper JW, Walter JC ., Mol Cell. September 1, 2006; 23 (5): 709-21.
Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium ( Kir2.1) channels. , Xie LH, John SA, Ribalet B, Weiss JN., J Gen Physiol. December 1, 2005; 126 (6): 541-9.
Sensitization and translocation of TRPV1 by insulin and IGF-I. , Van Buren JJ, Bhat S, Rotello R, Pauza ME, Premkumar LS., Mol Pain. April 27, 2005; 1 17.