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Summary Expression Phenotypes Gene Literature (35) GO Terms (6) Nucleotides (129) Proteins (41) Interactants (64) Wiki
XB-GENEPAGE-975266

Papers associated with dhfr



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Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II., Thompson NE, Steinberg TH, Aronson DB, Burgess RR., J Biol Chem. July 5, 1989; 264 (19): 11511-20.

Expression of murine dihydrofolate reductase complementary DNA in oocytes of Xenopus laevis., Itoh N, Mori K, Toga K, Ikegami S., Int J Biochem. January 1, 1991; 23 (4): 491-7.

The C terminus of mouse ornithine decarboxylase confers rapid degradation on dihydrofolate reductase. Support for the pest hypothesis., Loetscher P, Pratt G, Rechsteiner M., J Biol Chem. June 15, 1991; 266 (17): 11213-20.

Cloning and expression of the canine interferon-gamma gene., Devos K, Duerinck F, Van Audenhove K, Fiers W., J Interferon Res. April 1, 1992; 12 (2): 95-102.

A long-lived batch reaction system of cell-free protein synthesis., Kawarasaki Y, Kawai T, Nakano H, Yamane T., Anal Biochem. April 10, 1995; 226 (2): 320-4.

A distinct G1 step required to specify the Chinese hamster DHFR replication origin., Wu JR, Gilbert DM., Science. March 1, 1996; 271 (5253): 1270-2.

Chromosome architecture can dictate site-specific initiation of DNA replication in Xenopus egg extracts., Lawlis SJ, Keezer SM, Wu JR, Gilbert DM., J Cell Biol. December 1, 1996; 135 (5): 1207-18.

The replication origin decision point is a mitogen-independent, 2-aminopurine-sensitive, G1-phase event that precedes restriction point control., Wu JR, Gilbert DM., Mol Cell Biol. August 1, 1997; 17 (8): 4312-21.

Origin-specific initiation of mammalian nuclear DNA replication in a Xenopus cell-free system., Wu JR, Yu G, Gilbert DM., Methods. November 1, 1997; 13 (3): 313-24.

Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates., Pasquinelli AE, Powers MA, Lund E, Forbes D, Dahlberg JE., Proc Natl Acad Sci U S A. December 23, 1997; 94 (26): 14394-9.

Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin., Wu JR, Keezer SM, Gilbert DM., EMBO J. March 16, 1998; 17 (6): 1810-8.

In-vitro activity of lytic peptides alone and in combination with macrolides and inhibitors of dihydrofolate reductase against Pneumocystis carinii., Cirioni O, Giacometti A, Barchiesi F, Scalise G., J Antimicrob Chemother. October 1, 1998; 42 (4): 445-51.

Regulation of mammalian replication origin usage in Xenopus egg extract., Dimitrova DS, Gilbert DM., J Cell Sci. October 1, 1998; 111 ( Pt 19) 2989-98.

Analysis of mammalian origin specification in ORC-depleted Xenopus egg extracts., Yu G, Wu JR, Gilbert DM., Genes Cells. November 1, 1998; 3 (11): 709-20.

Nucleoskeleton and initiation of DNA replication in metazoan cells., Ortega JM, DePamphilis ML., J Cell Sci. December 18, 1998; 111 ( Pt 24) 3663-73.

Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex., Dimitrova DS, Todorov IT, Melendy T, Gilbert DM., J Cell Biol. August 23, 1999; 146 (4): 709-22.                    

The spatial position and replication timing of chromosomal domains are both established in early G1 phase., Dimitrova DS, Gilbert DM., Mol Cell. December 1, 1999; 4 (6): 983-93.

Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei., Li CJ, Bogan JA, Natale DA, DePamphilis ML., J Cell Sci. March 1, 2000; 113 ( Pt 5) 887-98.

Lovastatin arrests CHO cells between the origin decision point and the restriction point., Wu JR, Gilbert DM., FEBS Lett. November 3, 2000; 484 (2): 108-12.

The replication timing program of the Chinese hamster beta-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase., Li F, Chen J, Izumi M, Butler MC, Keezer SM, Gilbert DM., J Cell Biol. July 23, 2001; 154 (2): 283-92.          

Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle., Okuno Y, McNairn AJ, den Elzen N, Pines J, Gilbert DM., EMBO J. August 1, 2001; 20 (15): 4263-77.

Mammalian nuclei become licensed for DNA replication during late telophase., Dimitrova DS, Prokhorova TA, Blow JJ, Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.

Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism., Keezer SM, Gilbert DM., Exp Cell Res. February 1, 2002; 273 (1): 54-64.

The Chinese hamster dihydrofolate reductase replication origin decision point follows activation of transcription and suppresses initiation of replication within transcription units., Sasaki T, Ramanathan S, Okuno Y, Kumagai C, Shaikh SS, Gilbert DM., Mol Cell Biol. February 1, 2006; 26 (3): 1051-62.

Nuclear transcription is essential for specification of mammalian replication origins., Dimitrova DS., Genes Cells. July 1, 2006; 11 (7): 829-44.

Discrete functional elements required for initiation activity of the Chinese hamster dihydrofolate reductase origin beta at ectopic chromosomal sites., Gray SJ, Liu G, Altman AL, Small LE, Fanning E., Exp Cell Res. January 1, 2007; 313 (1): 109-20.

Role of poly (A) tail as an identity element for mRNA nuclear export., Fuke H, Ohno M., Nucleic Acids Res. February 1, 2008; 36 (3): 1037-49.              

Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality., Slavic K, Straschil U, Reininger L, Doerig C, Morin C, Tewari R, Krishna S., Mol Microbiol. March 1, 2010; 75 (6): 1402-13.              

G2 phase chromatin lacks determinants of replication timing., Lu J, Li F, Murphy CS, Davidson MW, Gilbert DM., J Cell Biol. June 14, 2010; 189 (6): 967-80.                

p54nrb/NonO and PSF promote U snRNA nuclear export by accelerating its export complex assembly., Izumi H, McCloskey A, Shinmyozu K, Ohno M., Nucleic Acids Res. April 1, 2014; 42 (6): 3998-4007.          

Molecular cloning, expression, and signaling pathway of four melanin-concentrating hormone receptors from Xenopus tropicalis., Kobayashi Y, Hamamoto A, Hirayama T, Saito Y., Gen Comp Endocrinol. February 1, 2015; 212 114-23.                

Exportin-5 mediates nuclear export of SRP RNA in vertebrates., Takeiwa T, Taniguchi I, Ohno M., Genes Cells. April 1, 2015; 20 (4): 281-91.          

The role of folate metabolism in orofacial development and clefting., Wahl SE, Kennedy AE, Wyatt BH, Moore AD, Pridgen DE, Cherry AM, Mavila CB, Dickinson AJ., Dev Biol. September 1, 2015; 405 (1): 108-22.                                  

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities., Pulcini S, Staines HM, Lee AH, Shafik SH, Bouyer G, Moore CM, Daley DA, Hoke MJ, Altenhofen LM, Painter HJ, Mu J, Ferguson DJ, Llinás M, Martin RE, Fidock DA, Cooper RA, Krishna S., Sci Rep. September 30, 2015; 5 14552.            

An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells., Ollech D, Pflästerer T, Shellard A, Zambarda C, Spatz JP, Marcq P, Mayor R, Wombacher R, Cavalcanti-Adam EA., Nat Commun. January 24, 2020; 11 (1): 472.                                  

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