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Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage. , Hong J, Kwon KY, Jang DG, Kwon T , Yoon H, Park TJ., Biomed Pharmacother. May 1, 2024; 174 116434.
Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2. , Ewart G, Bobardt M, Bentzen BH, Yan Y, Thomson A, Klumpp K, Becker S, Rosenkilde MM, Miller M, Gallay P., PLoS Pathog. August 1, 2023; 19 (8): e1011328.
Xenopus: An alternative model system for identifying muco-active agents. , Sim HJ, Kim SH, Myung KJ, Kwon T , Lee HS , Lee HS , Park TJ., PLoS One. February 14, 2018; 13 (2): e0193310.
Counteracting suppression of CFTR and voltage-gated K+ channels by a bacterial pathogenic factor with the natural product tannic acid. , Ramu Y, Xu Y , Xu Y , Shin HG, Lu Z., Elife. October 14, 2014; 3 e03683.
Exploiting polypharmacology for drug target deconvolution. , Gujral TS, Peshkin L , Kirschner MW ., Proc Natl Acad Sci U S A. April 1, 2014; 111 (13): 5048-53.
Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase. , King JD , Lee J , Riemen CE, Neumann D, Xiong S, Foskett JK, Mehta A, Muimo R, Hallows KR., J Biol Chem. September 28, 2012; 287 (40): 33389-400.
AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR. , King JD , Fitch AC, Lee JK , McCane JE, Mak DO, Foskett JK, Hallows KR., Am J Physiol Cell Physiol. July 1, 2009; 297 (1): C94-101.
Epithelial barrier modulation by a channel forming peptide. , Somasekharan S, Brandt R, Iwamoto T, Tomich JM, Schultz BD., J Membr Biol. March 1, 2008; 222 (1): 17-30.
ENaC alpha-subunit variants are expressed in lung epithelial cells and are suppressed by oxidative stress. , Xu H, Chu S ., Am J Physiol Lung Cell Mol Physiol. December 1, 2007; 293 (6): L1454-62.
Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus. , Chen JA , Voigt J, Gilchrist M , Papalopulu N , Amaya E ., Mech Dev. March 1, 2005; 122 (3): 307-31.
Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells. , Hallows KR, McCane JE, Kemp BE, Witters LA, Foskett JK., J Biol Chem. January 10, 2003; 278 (2): 998-1004.
Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator. , Zhang H , Peters KW, Sun F, Marino CR, Lang J, Burgoyne RD, Frizzell RA., J Biol Chem. August 9, 2002; 277 (32): 28948-58.
E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells. , Sun F, Hug MJ, Lewarchik CM, Yun CH, Bradbury NA, Frizzell RA., J Biol Chem. September 22, 2000; 275 (38): 29539-46.