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Summary Expression Phenotypes Gene Literature (44) GO Terms (10) Nucleotides (175) Proteins (96) Interactants (83) Wiki
XB-GENEPAGE-991125

Papers associated with cacna1c



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Multiple structural elements contribute to voltage-dependent facilitation of neuronal alpha 1C (CaV1.2) L-type calcium channels., Altier C, Spaetgens RL, Nargeot J, Bourinet E, Zamponi GW., Neuropharmacology. June 1, 2001; 40 (8): 1050-7.

Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line., Scholze A, Plant TD, Dolphin AC, Nürnberg B., Mol Endocrinol. July 1, 2001; 15 (7): 1211-21.

Voltage-dependent acceleration of Ca(v)1.2 channel current decay by (+)- and (-)-isradipine., Berjukow S, Hering S., Br J Pharmacol. August 1, 2001; 133 (7): 959-66.

On the role of Ca(2+)- and voltage-dependent inactivation in Ca(v)1.2 sensitivity for the phenylalkylamine (-)gallopamil., Sokolov S, Timin E, Hering S., Circ Res. October 12, 2001; 89 (8): 700-8.

State-dependent inhibition of inactivation-deficient Ca(V)1.2 and Ca(V)2.3 channels by mibefradil., Bernatchez G, Sauvé R, Parent L., J Membr Biol. November 15, 2001; 184 (2): 143-59.

Ionic dependence of Ca2+ channel modulation by syntaxin 1A., Wiser O, Cohen R, Atlas D., Proc Natl Acad Sci U S A. March 19, 2002; 99 (6): 3968-73.

Coexpression of a Ca(v)1.2 protein lacking an N-terminus and the first domain specifically suppresses L-type calcium channel activity., Ebihara T, Komiya Y, Izumi-Nakaseko H, Adachi-Akahane S, Okabe S, Okamura Y., FEBS Lett. October 9, 2002; 529 (2-3): 203-7.

The C2A domain of synaptotagmin alters the kinetics of voltage-gated Ca2+ channels Ca(v)1.2 (Lc-type) and Ca(v)2.3 (R-type)., Cohen R, Elferink LA, Atlas D., J Biol Chem. March 14, 2003; 278 (11): 9258-66.

Syntaxin 1A modulates the voltage-gated L-type calcium channel (Ca(v)1.2) in a cooperative manner., Arien H, Wiser O, Arkin IT, Leonov H, Atlas D., J Biol Chem. August 1, 2003; 278 (31): 29231-9.

R-type voltage-gated Ca(2+) channel interacts with synaptic proteins and recruits synaptotagmin to the plasma membrane of Xenopus oocytes., Cohen R, Atlas D., Neuroscience. January 1, 2004; 128 (4): 831-41.

Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation., Yasuda T, Lewis RJ, Adams DJ., J Gen Physiol. April 1, 2004; 123 (4): 401-16.                  

Assembly of a Ca2+-dependent BK channel signaling complex by binding to beta2 adrenergic receptor., Liu G, Shi J, Yang L, Cao L, Park SM, Cui J, Marx SO., EMBO J. June 2, 2004; 23 (11): 2196-205.

Roles of molecular regions in determining differences between voltage dependence of activation of CaV3.1 and CaV1.2 calcium channels., Li J, Stevens L, Klugbauer N, Wray D., J Biol Chem. June 25, 2004; 279 (26): 26858-67.

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism., Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT., Cell. October 1, 2004; 119 (1): 19-31.

Negatively charged residues in the N-terminal of the AID helix confer slow voltage dependent inactivation gating to CaV1.2., Dafi O, Berrou L, Dodier Y, Raybaud A, Sauvé R, Parent L., Biophys J. November 1, 2004; 87 (5): 3181-92.

Functional architecture of the inner pore of a voltage-gated Ca2+ channel., Zhen XG, Xie C, Fitzmaurice A, Schoonover CE, Orenstein ET, Yang J., J Gen Physiol. September 1, 2005; 126 (3): 193-204.                    

A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel., Livneh A, Cohen R, Atlas D., Neuroscience. January 1, 2006; 139 (4): 1275-87.

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB., Zhang H, Fu Y, Altier C, Platzer J, Surmeier DJ, Bezprozvanny I., Eur J Neurosci. May 1, 2006; 23 (9): 2297-310.

Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha)., Kanevsky N, Dascal N., J Gen Physiol. July 1, 2006; 128 (1): 15-36.                

Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases., Seu L, Pitt GS., J Gen Physiol. November 1, 2006; 128 (5): 605-13.          

The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels., Raybaud A, Dodier Y, Bissonnette P, Simoes M, Bichet DG, Sauvé R, Parent L., J Biol Chem. December 22, 2006; 281 (51): 39424-36.

Depolarization-evoked secretion requires two vicinal transmembrane cysteines of syntaxin 1A., Cohen R, Marom M, Atlas D., PLoS One. December 5, 2007; 2 (12): e1273.                

Reconstitution of depolarization and Ca2+-evoked secretion in Xenopus oocytes monitored by membrane capacitance., Cohen R, Schmitt BM, Atlas D., Methods Mol Biol. January 1, 2008; 440 269-82.

Mutations of nonconserved residues within the calcium channel alpha1-interaction domain inhibit beta-subunit potentiation., Gonzalez-Gutierrez G, Miranda-Laferte E, Naranjo D, Hidalgo P, Neely A., J Gen Physiol. September 1, 2008; 132 (3): 383-95.                        

Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel., Cens T, Leyris JP, Charnet P., Pflugers Arch. November 1, 2008; 457 (2): 417-30.

Characterization of the calmodulin-binding site in the N terminus of CaV1.2., Benmocha A, Almagor L, Oz S, Hirsch JA, Dascal N., Channels (Austin). January 1, 2009; 3 (5): 337-42.

Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation., Findeisen F, Minor DL., J Gen Physiol. March 1, 2009; 133 (3): 327-43.              

Cloning and characterization of voltage-gated calcium channel alpha1 subunits in Xenopus laevis during development., Lewis BB, Wester MR, Miller LE, Nagarkar MD, Johnson MB, Saha MS., Dev Dyn. November 1, 2009; 238 (11): 2891-902.                                

Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes., Gonzalez-Gutierrez G, Miranda-Laferte E, Contreras G, Neely A, Hidalgo P., Channels (Austin). January 1, 2010; 4 (1): 42-50.

Calmodulin overexpression does not alter Cav1.2 function or oligomerization state., Findeisen F, Tolia A, Arant R, Kim EY, Isacoff E, Minor DL., Channels (Austin). January 1, 2011; 5 (4): 320-4.

Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits., Yang L, Katchman A, Morrow JP, Doshi D, Marx SO., FASEB J. March 1, 2011; 25 (3): 928-36.

AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the CaV1.2 subunit., Altier C, Dubel SJ, Barrere C, Jarvis SE, Stotz SC, Scott JD, Nargeot J, Zamponi GW, Bourinet E., Channels (Austin). January 1, 2012; 6 (3): 157-65.

Voltage-driven Ca(2+) binding at the L-type Ca(2+) channel triggers cardiac excitation-contraction coupling prior to Ca(2+) influx., Gez LS, Hagalili Y, Shainberg A, Atlas D., Biochemistry. December 4, 2012; 51 (48): 9658-66.

Competitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2+ channels by calmodulin and Ca2+-binding protein 1., Oz S, Benmocha A, Sasson Y, Sachyani D, Almagor L, Lee A, Hirsch JA, Dascal N., J Biol Chem. May 3, 2013; 288 (18): 12680-91.

Coxsackievirus B3 modulates cardiac ion channels., Steinke K, Sachse F, Ettischer N, Strutz-Seebohm N, Henrion U, Rohrbeck M, Klosowski R, Wolters D, Brunner S, Franz WM, Pott L, Munoz C, Kandolf R, Schulze-Bahr E, Lang F, Klingel K, Seebohm G., FASEB J. October 1, 2013; 27 (10): 4108-21.

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels., Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD., Biochem Pharmacol. May 15, 2014; 89 (2): 276-86.

Selective modulation of cellular voltage-dependent calcium channels by hyperbaric pressure-a suggested HPNS partial mechanism., Aviner B, Gradwohl G, Mor Aviner M, Levy S, Grossman Y., Front Cell Neurosci. May 27, 2014; 8 136.                    

Age-related homeostatic midchannel proteolysis of neuronal L-type voltage-gated Ca²⁺ channels., Michailidis IE, Abele-Henckels K, Zhang WK, Lin B, Yu Y, Geyman LS, Ehlers MD, Pnevmatikakis EA, Yang J., Neuron. June 4, 2014; 82 (5): 1045-57.

The role of voltage-gated calcium channels in neurotransmitter phenotype specification: Coexpression and functional analysis in Xenopus laevis., Lewis BB, Miller LE, Herbst WA, Saha MS., J Comp Neurol. August 1, 2014; 522 (11): 2518-31.                          

Asn-Linked Glycosylation Contributes to Surface Expression and Voltage-Dependent Gating of Cav1.2 Ca²⁺ Channel., Park HJ, Min SH, Won YJ, Lee JH., J Microbiol Biotechnol. August 1, 2015; 25 (8): 1371-9.

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3., Park SJ, Min SH, Kang HW, Lee JH., Biochim Biophys Acta. October 1, 2015; 1848 (10 Pt A): 2092-100.

Protein kinase A regulates C-terminally truncated CaV 1.2 in Xenopus oocytes: roles of N- and C-termini of the α1C subunit., Oz S, Pankonien I, Belkacemi A, Flockerzi V, Klussmann E, Haase H, Dascal N., J Physiol. May 15, 2017; 595 (10): 3181-3202.

Calcium Signaling in Vertebrate Development and Its Role in Disease., Paudel S, Sindelar R, Saha M., Int J Mol Sci. October 30, 2018; 19 (11):     

Trpc1 as the Missing Link Between the Bmp and Ca2+ Signalling Pathways During Neural Specification in Amphibians., Néant I, Leung HC, Webb SE, Miller AL, Miller AL, Moreau M, Leclerc C., Sci Rep. November 5, 2019; 9 (1): 16049.                                    

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