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Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem-implications for channelopathies. , Allam S, Levenson-Palmer R, Chia Chang Z, Kaur S, Cernuda B, Raman A, Booth A, Dobbins S, Suppa G, Yang J , Buraei Z., Front Physiol. January 1, 2023; 14 1155976.
Direct inhibition of CaV2.3 by Gem is dynamin dependent and does not require a direct alfa/beta interaction. , Contreras GF, Saavedra J, Navarro-Quezada N, Mellado G, Gonzalez C, Neely A., Biochem Biophys Res Commun. January 1, 2022; 586 107-113.
Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts. , Larsen NB, Gao AO, Sparks JL, Gallina I, Wu RA, Mann M, Räschle M, Walter JC , Duxin JP ., Mol Cell. February 7, 2019; 73 (3): 574-588.e7.
Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression. , Aze A, Sannino V, Soffientini P, Bachi A, Costanzo V., Nat Cell Biol. June 1, 2016; 18 (6): 684-91.
Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link. , Budzowska M, Graham TG, Sobeck A, Waga S, Walter JC ., EMBO J. July 14, 2015; 34 (14): 1971-85.
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. , Johnson ZL, Lee JH , Lee K, Lee M, Kwon DY, Hong J, Lee SY., Elife. July 31, 2014; 3 e03604.
Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly. , Soto X , Li J, Lea R, Dubaissi E , Papalopulu N , Amaya E ., Proc Natl Acad Sci U S A. July 2, 2013; 110 (27): 11029-34.
Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes. , Klein SL, Neilson KM , Orban J, Yaklichkin S , Hoffbauer J, Mood K, Daar IO , Moody SA ., PLoS One. April 4, 2013; 8 (4): e61845.
Molecular determinants of Gem protein inhibition of P/Q-type Ca2+ channels. , Fan M, Zhang WK, Buraei Z, Yang J ., J Biol Chem. June 29, 2012; 287 (27): 22749-58.
Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate. , Neilson KM , Klein SL, Mhaske P, Mood K, Daar IO , Moody SA ., Dev Biol. May 15, 2012; 365 (2): 363-75.
Geminin is required for zygotic gene expression at the Xenopus mid- blastula transition. , Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ., PLoS One. January 1, 2012; 7 (5): e38009.
The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module. , Rogers CD, Ferzli GS, Casey ES ., BMC Dev Biol. January 26, 2011; 11 74.
Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation. , Schäfer A, Schomacher L, Barreto G, Döderlein G, Niehrs C ., PLoS One. November 19, 2010; 5 (11): e14060.
Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction. , Fan M, Buraei Z, Luo HR, Levenson-Palmer R, Yang J ., Proc Natl Acad Sci U S A. August 17, 2010; 107 (33): 14887-92.
Geminin and Brahma act antagonistically to regulate EGFR-Ras- MAPK signaling in Drosophila. , Herr A, Mckenzie L, Suryadinata R, Sadowski M, Parsons LM, Sarcevic B, Richardson HE., Dev Biol. August 1, 2010; 344 (1): 36-51.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
RGK GTPase-dependent CaV2.1 Ca2+ channel inhibition is independent of CaVbeta-subunit-induced current potentiation. , Leyris JP, Gondeau C, Charnet A, Delattre C, Rousset M, Cens T, Charnet P., FASEB J. August 1, 2009; 23 (8): 2627-38.
foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation. , Yan B , Neilson KM , Moody SA ., Dev Biol. May 1, 2009; 329 (1): 80-95.
Replication initiation complex formation in the absence of nuclear function in Xenopus. , Krasinska L, Fisher D ., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.
Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives. , Rogers CD, Harafuji N, Archer T, Cunningham DD , Casey ES ., Mech Dev. January 1, 2009; 126 (1-2): 42-55.
Plx1 is required for chromosomal DNA replication under stressful conditions. , Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.
Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1. , Nakagomi-Hagihara R, Nakai D, Tokui T, Abe T, Ikeda T., Xenobiotica. May 1, 2007; 37 (5): 474-86.
Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases. , Seu L, Pitt GS., J Gen Physiol. November 1, 2006; 128 (5): 605-13.
Subcellular translocation signals regulate Geminin activity during embryonic development. , Boos A, Lee A, Thompson DM, Kroll KL ., Biol Cell. June 1, 2006; 98 (6): 363-75.
Tcf- and Vent-binding sites regulate neural-specific geminin expression in the gastrula embryo. , Taylor JJ, Wang T, Kroll KL ., Dev Biol. January 15, 2006; 289 (2): 494-506.
A small gem with great powers: geminin keeps neural progenitors thriving. , Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.
Geminin regulates neuronal differentiation by antagonizing Brg1 activity. , Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL ., Genes Dev. July 15, 2005; 19 (14): 1723-34.
Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts. , Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.
Direct interaction of geminin and Six3 in eye development. , Del Bene F, Tessmar-Raible K, Wittbrodt J ., Nature. February 19, 2004; 427 (6976): 745-9.
Identification of protein kinase C (PKC) isoforms in teleostean, amphibian and avian pigment cells. , Isoldi MC, Matioli SR, Castrucci AM, de Lima LH, Visconti MA, Rebouças NA., Pigment Cell Res. December 1, 2003; 16 (6): 639-43.
DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. , Stokes MP, Van Hatten R, Lindsay HD , Michael WM., J Cell Biol. September 2, 2002; 158 (5): 863-72.
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis. , Quinn LM, Herr A, McGarry TJ, Richardson H., Genes Dev. October 15, 2001; 15 (20): 2741-54.
Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/ Gem. , Béguin P, Nagashima K, Gonoi T, Shibasaki T, Takahashi K, Kashima Y, Ozaki N, Geering K, Iwanaga T, Seino S., Nature. June 7, 2001; 411 (6838): 701-6.
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation. , Kroll KL , Salic AN, Evans LM, Kirschner MW ., Development. August 1, 1998; 125 (16): 3247-58.