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Summary Expression Phenotypes Gene Literature (531) GO Terms (11) Nucleotides (79) Proteins (47) Interactants (1198) Wiki
XB-GENEPAGE-487168

Papers associated with nodal1



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Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis., Xanthos JB, Kofron M, Wylie C, Heasman J., Development. January 1, 2001; 128 (2): 167-80.

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads., Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR., J Biol Chem. January 5, 2001; 276 (1): 656-61.

The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. ., Faucourt M, Houliston E, Besnardeau L, Kimelman D, Lepage T., Dev Biol. January 15, 2001; 229 (2): 287-306.                

Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis., Brizuela BJ, Wessely O, De Robertis EM., Dev Biol. February 15, 2001; 230 (2): 217-29.                

In synergy with noggin and follistatin, Xenopus nodal-related gene induces sonic hedgehog on notochord and floor plate., Ito Y, Kuhara S, Tashiro K., Biochem Biophys Res Commun. March 2, 2001; 281 (3): 714-9.      

NMDA and glycine regulate the affinity of the Mg2+-block site in NR1-1a/NR2A NMDA receptor channels expressed in Xenopus oocytes., Liu Y, Hill RH, Arhem P, von Euler G., Life Sci. March 9, 2001; 68 (16): 1817-26.

An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity., Tai KK, Blondelle SE, Ostresh JM, Houghten RA, Montal M., Proc Natl Acad Sci U S A. March 13, 2001; 98 (6): 3519-24.

Protein kinase C modulates NMDA receptor trafficking and gating., Lan JY, Skeberdis VA, Jover T, Grooms SY, Lin Y, Araneda RC, Zheng X, Bennett MV, Zukin RS., Nat Neurosci. April 1, 2001; 4 (4): 382-90.

A role for BMP signalling in heart looping morphogenesis in Xenopus., Breckenridge RA, Mohun TJ, Amaya E., Dev Biol. April 1, 2001; 232 (1): 191-203.          

Arkadia enhances nodal-related signalling to induce mesendoderm., Niederländer C, Walsh JJ, Episkopou V, Jones CM., Nature. April 12, 2001; 410 (6830): 830-4.  

Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms., Yeo C, Whitman M., Mol Cell. May 1, 2001; 7 (5): 949-57.

Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus., Wessely O, Agius E, Oelgeschläger M, Pera EM, De Robertis EM., Dev Biol. June 1, 2001; 234 (1): 161-73.              

Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors., Meddows E, Le Bourdelles B, Grimwood S, Wafford K, Sandhu S, Whiting P, McIlhinney RA., J Biol Chem. June 1, 2001; 276 (22): 18795-803.

Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5., Reiter JF, Verkade H, Stainier DY., Dev Biol. June 15, 2001; 234 (2): 330-8.

Suppression of head formation by Xmsx-1 through the inhibition of intracellular nodal signaling., Yamamoto TS, Takagi C, Hyodo AC, Ueno N., Development. July 1, 2001; 128 (14): 2769-79.      

High-affinity Zn block in recombinant N-methyl-D-aspartate receptors with cysteine substitutions at the Q/R/N site., Amar M, Perin-Dureau F, Neyton J., Biophys J. July 1, 2001; 81 (1): 107-16.

Timing of endogenous activin-like signals and regional specification of the Xenopus embryo., Lee MA, Heasman J, Whitman M., Development. August 1, 2001; 128 (15): 2939-52.            

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development., Reissmann E, Jörnvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, Persico MG, Ibáñez CF, Brivanlou AH., Genes Dev. August 1, 2001; 15 (15): 2010-22.                

VegT activation of Sox17 at the midblastula transition alters the response to nodal signals in the vegetal endoderm domain., Engleka MJ, Craig EJ, Kessler DS., Dev Biol. September 1, 2001; 237 (1): 159-72.                

Early posterior/ventral fate specification in the vertebrate embryo., Muñoz-Sanjuán I, H-Brivanlou A., Dev Biol. September 1, 2001; 237 (1): 1-17.      

TGF-beta signalling pathways in early Xenopus development., Hill CS., Curr Opin Genet Dev. October 1, 2001; 11 (5): 533-40.    

Fucosylation of Cripto is required for its ability to facilitate nodal signaling., Schiffer SG, Foley S, Kaffashan A, Hronowski X, Zichittella AE, Yeo CY, Miatkowski K, Adkins HB, Damon B, Whitman M, Salomon D, Sanicola M, Williams KP., J Biol Chem. October 12, 2001; 276 (41): 37769-78.

Nodal signaling in early vertebrate embryos: themes and variations., Whitman M., Dev Cell. November 1, 2001; 1 (5): 605-17.

Calmodulin binds to inv protein: implication for the regulation of inv function., Yasuhiko Y, Imai F, Ookubo K, Takakuwa Y, Shiokawa K, Yokoyama T., Dev Growth Differ. December 1, 2001; 43 (6): 671-81.                

Multiple nodal-related genes act coordinately in Xenopus embryogenesis., Onuma Y, Takahashi S, Yokota C, Asashima M., Dev Biol. January 1, 2002; 241 (1): 94-105.

Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry., Kitaguchi T, Mizugishi K, Hatayama M, Aruga J, Mikoshiba K., Dev Growth Differ. February 1, 2002; 44 (1): 55-61.        

Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids., Malayev A, Gibbs TT, Farb DH., Br J Pharmacol. February 1, 2002; 135 (4): 901-9.

NMDA receptors formed by NR1 in Xenopus laevis oocytes do not contain the endogenous subunit XenU1., Green T, Rogers CA, Contractor A, Heinemann SF., Mol Pharmacol. February 1, 2002; 61 (2): 326-33.

Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits., Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D., Nature. February 14, 2002; 415 (6873): 793-8.

Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes., Rex M, Hilton E, Old R., Int J Dev Biol. March 1, 2002; 46 (2): 217-26.

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion., Sakuma R, Ohnishi Yi Y, Meno C, Fujii H, Juan H, Takeuchi J, Ogura T, Li E, Miyazono K, Hamada H., Genes Cells. April 1, 2002; 7 (4): 401-12.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling., Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW., Genes Dev. April 1, 2002; 16 (7): 820-35.    

Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons., Sasaki YF, Rothe T, Premkumar LS, Das S, Cui J, Talantova MV, Wong HK, Gong X, Chan SF, Zhang D, Nakanishi N, Sucher NJ, Lipton SA., J Neurophysiol. April 1, 2002; 87 (4): 2052-63.

PSD-95 eliminates Src-induced potentiation of NR1/NR2A-subtype NMDA receptor channels and reduces high-affinity zinc inhibition., Yamada Y, Iwamoto T, Watanabe Y, Sobue K, Inui M., J Neurochem. May 1, 2002; 81 (4): 758-64.

Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus., Eimon PM, Harland RM., Development. July 1, 2002; 129 (13): 3089-103.          

Conserved function for embryonic nodal cilia., Essner JJ, Vogan KJ, Wagner MK, Tabin CJ, Yost HJ, Brueckner M., Nature. July 4, 2002; 418 (6893): 37-8.

The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling., Altmann CR, Chang C, Muñoz-Sanjuán I, Bell E, Heke M, Rifkin DB, Brivanlou AH., Dev Biol. August 1, 2002; 248 (1): 118-27.                  

A component of the ARC/Mediator complex required for TGF beta/Nodal signalling., Kato Y, Habas R, Katsuyama Y, Näär AM, He X., Nature. August 8, 2002; 418 (6898): 641-6.

The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3., Houston DW, Kofron M, Resnik E, Langland R, Destree O, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4015-25.          

Molecular regulation of vertebrate early endoderm development., Shivdasani RA., Dev Biol. September 15, 2002; 249 (2): 191-203.      

The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus., Kumano G, Smith WC., Mech Dev. October 1, 2002; 118 (1-2): 45-56.    

Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning., Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M., Cell. October 4, 2002; 111 (1): 77-89.              

Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish., Poulain M, Lepage T., Development. November 1, 2002; 129 (21): 4901-14.

The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling., Bertocchini F, Stern CD., Dev Cell. November 1, 2002; 3 (5): 735-44.

Staggering of subunits in NMDAR channels., Sobolevsky AI, Rooney L, Wollmuth LP., Biophys J. December 1, 2002; 83 (6): 3304-14.

Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment., Green J., Dev Dyn. December 1, 2002; 225 (4): 392-408.

Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation., Branford WW, Yost HJ., Curr Biol. December 23, 2002; 12 (24): 2136-41.              

PKCgamma regulates syndecan-2 inside-out signaling during xenopus left-right development., Kramer KL, Barnette JE, Yost HJ., Cell. December 27, 2002; 111 (7): 981-90.                

EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1., Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF., Genes Dev. January 1, 2003; 17 (1): 31-6.

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