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Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication. , Coxon A, Maundrell K, Kearsey SE., Nucleic Acids Res. November 11, 1992; 20 (21): 5571-7.
A murine replication protein accumulates temporarily in the heterochromatic regions of nuclei prior to initiation of DNA replication. , Starborg M, Brundell E, Gell K, Larsson C, White I, Daneholt B, Höög C., J Cell Sci. March 1, 1995; 108 ( Pt 3) 927-34.
MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells. , Madine MA, Khoo CY, Mills AD, Laskey RA., Nature. June 1, 1995; 375 (6530): 421-4.
The possible involvement of replication-related proteins with a DEAD-box-like motif in cell-free DNA replication of Xenopus eggs. , Someya A, Shioda M., Biochem Biophys Res Commun. July 26, 1995; 212 (3): 1098-106.
The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts. , Madine MA, Khoo CY, Mills AD, Musahl C, Laskey RA., Curr Biol. November 1, 1995; 5 (11): 1270-9.
Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication. , Miyake S, Saito I, Kobayashi H, Yamashita S., Gene. October 10, 1996; 175 (1-2): 71-5.
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. , Donovan S, Harwood J, Drury LS, Diffley JF., Proc Natl Acad Sci U S A. May 27, 1997; 94 (11): 5611-6.
The RLF-M component of the replication licensing system forms complexes containing all six MCM/ P1 polypeptides. , Thömmes P, Kubota Y, Takisawa H, Blow JJ ., EMBO J. June 2, 1997; 16 (11): 3312-9.
Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. , Sato N, Arai K, Masai H., EMBO J. July 16, 1997; 16 (14): 4340-51.
Developmental regulation of MCM replication factors in Xenopus laevis. , Sible JC , Erikson E, Hendrickson M, Maller JL , Gautier J ., Curr Biol. March 12, 1998; 8 (6): 347-50.
Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus. , Coué M, Amariglio F, Maiorano D , Bocquet S, Méchali M., Exp Cell Res. December 15, 1998; 245 (2): 282-9.
Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex. , Dimitrova DS, Todorov IT, Melendy T, Gilbert DM., J Cell Biol. August 23, 1999; 146 (4): 709-22.
MCM proteins are associated with RNA polymerase II holoenzyme. , Yankulov K, Todorov I, Romanowski P, Licatalosi D, Cilli K, McCracken S, Laskey R, Bentley DL., Mol Cell Biol. September 1, 1999; 19 (9): 6154-63.
The spatial position and replication timing of chromosomal domains are both established in early G1 phase. , Dimitrova DS, Gilbert DM., Mol Cell. December 1, 1999; 4 (6): 983-93.
The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. , Sun W, Hola M, Pedley K, Tada S, Blow JJ , Todorov IT, Kearsey SE, Brooks RF., J Cell Sci. February 1, 2000; 113 ( Pt 4) 683-95.
Stepwise regulated chromatin assembly of MCM2-7 proteins. , Maiorano D , Lemaître JM, Méchali M., J Biol Chem. March 24, 2000; 275 (12): 8426-31.
The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells. , Madine MA, Swietlik M, Pelizon C, Romanowski P, Mills AD, Laskey RA., J Struct Biol. April 1, 2000; 129 (2-3): 198-210.
XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis. , Maiorano D , Moreau J , Méchali M., Nature. April 6, 2000; 404 (6778): 622-5.
Distinct phosphoisoforms of the Xenopus Mcm4 protein regulate the function of the Mcm complex. , Pereverzeva I, Whitmire E, Khan B, Coué M., Mol Cell Biol. May 1, 2000; 20 (10): 3667-76.
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. , Gillespie PJ, Li A, Blow JJ ., BMC Biochem. January 1, 2001; 2 15.
Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. , Wohlschlegel JA, Dhar SK, Prokhorova TA, Dutta A , Walter JC ., Mol Cell. February 1, 2002; 9 (2): 233-40.
Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae. , Devault A, Vallen EA, Yuan T, Green S , Bensimon A, Schwob E., Curr Biol. April 16, 2002; 12 (8): 689-94.
Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. , Hodgson B, Li A, Tada S, Blow JJ ., Curr Biol. April 16, 2002; 12 (8): 678-83.
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts. , Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC ., J Biol Chem. September 6, 2002; 277 (36): 33049-57.
Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. , Chou DM, Petersen P, Walter JC , Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC , Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.
Fission yeast Cdc23/ Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. , Gregan J, Lindner K, Brimage L, Franklin R, Namdar M, Hart EA, Aves SJ, Kearsey SE., Mol Biol Cell. September 1, 2003; 14 (9): 3876-87.
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination. , Li A, Blow JJ ., Nat Cell Biol. March 1, 2004; 6 (3): 260-7.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M, Score AJ, Blow JJ ., J Cell Biol. April 26, 2004; 165 (2): 181-90.
A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. , Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, Kornbluth S , Swaminathan K, Dutta A ., Mol Cell. July 23, 2004; 15 (2): 245-58.
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. , Pacek M, Walter JC ., EMBO J. September 15, 2004; 23 (18): 3667-76.
Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex. , Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC ., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.
DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process. , Shechter D , Ying CY, Gautier J ., J Biol Chem. October 29, 2004; 279 (44): 45586-93.
DNA replication licensing in somatic and germ cells. , Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI , Prevost AT, Blow JJ , Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.
Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. , Yoo HY, Shevchenko A, Shevchenko A, Dunphy WG ., J Biol Chem. December 17, 2004; 279 (51): 53353-64.
Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. , Arias EE, Walter JC ., Genes Dev. January 1, 2005; 19 (1): 114-26.
Functional domains of the Xenopus replication licensing factor Cdt1. , Ferenbach A, Li A, Brito-Martins M, Blow JJ ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.
Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts. , Maiorano D , Krasinska L, Lutzmann M, Mechali M ., Curr Biol. January 26, 2005; 15 (2): 146-53.
Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus. , Li A, Blow JJ ., EMBO J. January 26, 2005; 24 (2): 395-404.
Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts. , Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.
MCM8 is an MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation. , Maiorano D , Cuvier O, Danis E, Méchali M., Cell. February 11, 2005; 120 (3): 315-28.
Identification of full genes and proteins of MCM9, a novel, vertebrate-specific member of the MCM2-8 protein family. , Lutzmann M, Maiorano D , Méchali M., Gene. December 5, 2005; 362 51-6.
The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding. , Ying CY, Gautier J ., EMBO J. December 21, 2005; 24 (24): 4334-44.
Regulation of replication licensing by acetyltransferase Hbo1. , Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.
Comparative genomics on MCM8 orthologous genes reveals the transcriptional regulation by transcription factor E2F. , Hayashi R, Goto Y, Haga A, Kobayashi D, Ikeda R, Yoshida K., Gene. February 15, 2006; 367 126-34.
Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. , Pacek M, Tutter AV, Kubota Y, Takisawa H, Walter JC ., Mol Cell. February 17, 2006; 21 (4): 581-7.
Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts. , Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. , Woodward AM, Göhler T, Luciani MG, Oehlmann M, Ge X, Gartner A, Jackson DA, Blow JJ ., J Cell Biol. June 5, 2006; 173 (5): 673-83.
Deregulated replication licensing causes DNA fragmentation consistent with head-to- tail fork collision. , Davidson IF, Li A, Blow JJ ., Mol Cell. November 3, 2006; 24 (3): 433-43.
A Cdt1- geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus. , Lutzmann M, Maiorano D , Méchali M., EMBO J. December 13, 2006; 25 (24): 5764-74.