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Summary Expression Phenotypes Gene Literature (226) GO Terms (11) Nucleotides (305) Proteins (73) Interactants (446) Wiki
XB-GENEPAGE-921634

Papers associated with gnao1



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XenDB: full length cDNA prediction and cross species mapping in Xenopus laevis., Sczyrba A, Beckstette M, Brivanlou AH, Giegerich R, Altmann CR., BMC Genomics. April 1, 2005; 6 123.   


p90Rsk is not involved in cytostatic factor arrest in mouse oocytes., Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH., J Cell Biol. April 25, 2005; 169 (2): 227-31.   


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY, Koh YS, Jo SH., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.

Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes., Kim CS, Son SJ, Kim HS, Kim YD, Lee KS, Jeon BH, Kim KJ, Park JK, Park JB., Acta Pharmacol Sin. May 1, 2005; 26 (5): 551-8.

Camguk/CASK enhances Ether-á-go-go potassium current by a phosphorylation-dependent mechanism., Marble DD, Hegle AP, Snyder ED, Dimitratos S, Bryant PJ, Wilson GF., J Neurosci. May 18, 2005; 25 (20): 4898-907.

K channel subconductance levels result from heteromeric pore conformations., Chapman ML, VanDongen AM., J Gen Physiol. August 1, 2005; 126 (2): 87-103.   


Go G-proteins mediate rapid heterologous desensitization of G-protein coupled receptors in Xenopus oocytes., Van-Ham II, Oron Y., J Cell Physiol. August 1, 2005; 204 (2): 455-62.

Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation., Fernandez D, Ghanta A, Kinard KI, Sanguinetti MC., J Physiol. September 15, 2005; 567 (Pt 3): 737-55.

Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L, Li ZW, Du R, Yuan GH, Li W, Ren FX, Li J, Yang JG., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.

Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor., Bannister JP, Chanda B, Bezanilla F, Papazian DM., Proc Natl Acad Sci U S A. December 20, 2005; 102 (51): 18718-23.

The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M, Hatakeyama N, Malykhina AP, Yamazaki M, Momose Y, Akbarali HI., Anesth Analg. January 1, 2006; 102 (1): 98-103.

Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS, Diness TG, Christ T, Demnitz J, Ravens U, Olesen SP, Grunnet M., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.

Expression and functional characterization of the human ether-à-go-go-related gene (HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes., Aydar E, Palmer C., J Membr Biol. January 1, 2006; 211 (2): 115-26.

Mechanism of action of a novel human ether-a-go-go-related gene channel activator., Casis O, Olesen SP, Sanguinetti MC., Mol Pharmacol. February 1, 2006; 69 (2): 658-65.

Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH, Choi SY, Yun JH, Koh YS, Ho WK, Lee CO, Lee CO., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.

The D3-dopaminergic agonist 7-hydroxy-dipropylaminotetralin (7-OH-DPAT) increases cardiac action potential duration and blocks human ether-a-go-go-related gene K+ channel., Torres-Jácome J, Tejeda-Chávez HR, Rodríguez-Menchaca AA, Sánchez-Chapula JA, Navarro-Polanco RA., J Cardiovasc Pharmacol. May 1, 2006; 47 (5): 656-62.

Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY, Kim YJ, Kim KT, Choe H, Jo SH., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.

In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP, Alter M, Zitron E, Kiesecker C, Kathöfer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA., Toxicol Lett. August 20, 2006; 165 (2): 156-66.

Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating., Lin MC, Papazian DM., Channels (Austin). January 1, 2007; 1 (6): 429-37.

Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine., Siebrands CC, Friederich P., Anesthesiology. March 1, 2007; 106 (3): 523-31.

Pairing morphology with gene expression in thyroid hormone-induced intestinal remodeling and identification of a core set of TH-induced genes across tadpole tissues., Buchholz DR, Heimeier RA, Das B, Washington T, Shi YB., Dev Biol. March 15, 2007; 303 (2): 576-90.

Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel., Jo SH, Hong HK, Jung SJ, Chong SH, Yun JH, Koh YS, Choe H., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.

Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization., Schwoerer AP, Blütner C, Brandt S, Binder S, Siebrands CC, Ehmke H, Friederich P., Anesthesiology. May 1, 2007; 106 (5): 967-76.

Messages in the matrix: proteoglycans go the distance., Gallagher J., Dev Cell. August 1, 2007; 13 (2): 166-7.

Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator., Perry M, Sachse FB, Sanguinetti MC., Proc Natl Acad Sci U S A. August 21, 2007; 104 (34): 13827-32.

Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel., Jo SH, Hong HK, Chong SH, Choe H., Life Sci. January 30, 2008; 82 (5-6): 331-40.

Relationship between intracellular ice formation in oocytes of the mouse and Xenopus and the physical state of the external medium--a revisit., Mazur P, Kleinhans FW., Cryobiology. February 1, 2008; 56 (1): 22-7.

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants., Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W., Circulation. February 19, 2008; 117 (7): 866-75.

A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator., Perry M, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1044-51.

Structural basis for ether-a-go-go-related gene K+ channel subtype-dependent activation by niflumic acid., Fernandez D, Sargent J, Sachse FB, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1159-67.

A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation., Klement G, Nilsson J, Arhem P, Elinder F., Biophys J. April 15, 2008; 94 (8): 3014-22.

Topological mapping of the asymmetric drug binding to the human ether-à-go-go-related gene product (HERG) potassium channel by use of tandem dimers., Myokai T, Ryu S, Shimizu H, Oiki S., Mol Pharmacol. June 1, 2008; 73 (6): 1643-51.

Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)., Xu X, Recanatini M, Roberti M, Tseng GN., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.

[The persistent expression of HERG channel in Xenopus oocyte and alteration of current]., Wang XP, Li L, Zou AR, Tu DN, Liao YH., Zhongguo Ying Yong Sheng Li Xue Za Zhi. August 1, 2008; 24 (3): 329-33.

Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin., Tu DN, Zou AR, Liao YH, Du YM, Wang XP, Li L., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.

CaM kinase II initiates meiotic spindle depolymerization independently of APC/C activation., Reber S, Over S, Kronja I, Gruss OJ., J Cell Biol. December 15, 2008; 183 (6): 1007-17.   


Specificity of Gbetagamma signaling depends on Galpha subunit coupling with G-protein-sensitive K(+) channels., Geng X, Du XN, Rusinova R, Liu BY, Li F, Zhang X, Chen XJ, Logothetis DE, Zhang HL., Pharmacology. January 1, 2009; 84 (2): 82-90.

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels., Scholz EP, Niemer N, Hassel D, Zitron E, Bürgers HF, Bloehs R, Seyler C, Scherer D, Thomas D, Kathöfer S, Katus HA, Rottbauer WA, Karle CA., Biochem Biophys Res Commun. April 3, 2009; 381 (2): 159-64.

Resources and transgenesis techniques for functional genomics in Xenopus., Ogino H, Ochi H., Dev Growth Differ. May 1, 2009; 51 (4): 387-401.   


Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine., Hong HK, Jo SH., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.

Divalent cations slow activation of EAG family K+ channels through direct binding to S4., Zhang X, Bursulaya B, Lee CC, Lee CC, Chen B, Pivaroff K, Jegla T., Biophys J. July 8, 2009; 97 (1): 110-20.

The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel., Yang YC, Hsieh JY, Kuo CC., J Gen Physiol. August 1, 2009; 134 (2): 95-113.   


PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance., Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 20075-80.

Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK, Yoon WJ, Kim YH, Yoo ES, Jo SH., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.   


Studies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult., Heimeier RA, Das B, Buchholz DR, Fiorentino M, Shi YB., Genome Biol. January 1, 2010; 11 (5): R55.   


Dynamic expression of axon guidance cues required for optic tract development is controlled by fibroblast growth factor signaling., Atkinson-Leadbeater K, Bertolesi GE, Hehr CL, Webber CA, Cechmanek PB, McFarlane S., J Neurosci. January 13, 2010; 30 (2): 685-93.   


Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652., Xing J, Ma J, Zhang P, Fan X., Eur J Pharmacol. March 25, 2010; 630 (1-3): 1-9.

Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine., Hong HK, Park MH, Lee BH, Jo SH., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.

The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism., Gessner G, Macianskiene R, Starkus JG, Schönherr R, Heinemann SH., Eur J Pharmacol. April 25, 2010; 632 (1-3): 52-9.

Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening., Lin MC, Abramson J, Papazian DM., J Gen Physiol. May 1, 2010; 135 (5): 415-31.   

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