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Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. , Lee J , Platt KA, Censullo P, Ruiz i Altaba A ., Development. July 1, 1997; 124 (13): 2537-52.
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. , Dahmane N, Lee J , Lee J , Robins P, Heller P, Ruiz i Altaba A ., Nature. October 23, 1997; 389 (6653): 876-81.
Expression profile of Gli family members and Shh in normal and mutant mouse limb development. , Büscher D, Rüther U., Dev Dyn. January 1, 1998; 211 (1): 88-96.
Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog. , Ruiz i Altaba A ., Development. June 1, 1998; 125 (12): 2203-12.
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. , Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC., Development. July 1, 1998; 125 (14): 2533-43.
The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. , Hardcastle Z, Mo R, Hui CC, Sharpe PT., Development. August 1, 1998; 125 (15): 2803-11.
Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. , Motoyama J, Liu J , Mo R, Ding Q, Post M, Hui CC., Nat Genet. September 1, 1998; 20 (1): 54-7.
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. , Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S., J Biol Chem. March 19, 1999; 274 (12): 8143-52.
Gli proteins encode context-dependent positive and negative functions: implications for development and disease. , Ruiz i Altaba A ., Development. June 1, 1999; 126 (14): 3205-16.
Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. , Pearse RV, Collier LS, Scott MP, Tabin CJ., Dev Biol. August 15, 1999; 212 (2): 323-36.
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. , Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H., Development. September 1, 1999; 126 (17): 3915-24.
Neuralization of the Xenopus embryo by inhibition of p300/ CREB-binding protein function. , Kato Y , Shi Y , Shi Y , He X ., J Neurosci. November 1, 1999; 19 (21): 9364-73.
Distinct and regulated activities of human Gli proteins in Drosophila. , von Mering C, Basler K., Curr Biol. November 18, 1999; 9 (22): 1319-22.
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. , Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL., Development. April 1, 2000; 127 (8): 1593-605.
Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. , Borycki A, Brown AM, Emerson CP., Development. May 1, 2000; 127 (10): 2075-87.
Regulation of gli activity by all-trans retinoic acid in mouse keratinocytes. , Goyette P, Allan D, Peschard P, Chen CF , Wang W, Lohnes D., Cancer Res. October 1, 2000; 60 (19): 5386-9.
Gli2 functions in FGF signaling during antero- posterior patterning. , Brewster R , Mullor JL, Ruiz i Altaba A ., Development. October 1, 2000; 127 (20): 4395-405.
Zic3 is involved in the left- right specification of the Xenopus embryo. , Kitaguchi T, Nagai T, Nakata K, Aruga J , Mikoshiba K ., Development. November 1, 2000; 127 (22): 4787-95.
Xrel3 is required for head development in Xenopus laevis. , Lake BB, Ford R, Kao KR ., Development. January 1, 2001; 128 (2): 263-73.
Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. , Mizugishi K, Aruga J , Nakata K, Mikoshiba K ., J Biol Chem. January 19, 2001; 276 (3): 2180-8.
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. , Lamar E, Kintner C , Goulding M., Development. April 1, 2001; 128 (8): 1335-46.
Expression pattern of Irx1 and Irx2 during mouse digit development. , Zülch A, Becker MB, Gruss P ., Mech Dev. August 1, 2001; 106 (1-2): 159-62.
Irx1 and Irx2 expression in early lung development. , Becker MB, Zülch A, Bosse A, Gruss P ., Mech Dev. August 1, 2001; 106 (1-2): 155-8.
Gli1 can rescue the in vivo function of Gli2. , Bai CB, Joyner AL., Development. December 1, 2001; 128 (24): 5161-72.
Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development. , Takabatake Y, Takabatake T, Sasagawa S, Takeshima K ., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. , Perron M , Boy S, Amato MA, Viczian A , Koebernick K, Pieler T , Harris WA ., Development. April 1, 2003; 130 (8): 1565-77.
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. , Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF., Development. April 1, 2003; 130 (8): 1549-64.
The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. , Meyer NP, Roelink H., Dev Biol. May 15, 2003; 257 (2): 343-55.
Expression profile of Xenopus banded hedgehog, a homolog of mouse Indian hedgehog, is related to the late development of endochondral ossification in Xenopus laevis. , Moriishi T, Shibata Y, Tsukazaki T, Yamaguchi A ., Biochem Biophys Res Commun. March 25, 2005; 328 (4): 867-73.
The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells. , Offner N, Duval N, Jamrich M , Durand B ., Development. April 1, 2005; 132 (8): 1807-18.
Cooperative requirement of the Gli proteins in neurogenesis. , Nguyen V, Chokas AL, Stecca B, Ruiz i Altaba A ., Development. July 1, 2005; 132 (14): 3267-79.
Dual degradation signals control Gli protein stability and tumor formation. , Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK , Oro AE., Genes Dev. February 1, 2006; 20 (3): 276-81.
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. , Koide T, Hayata T, Cho KW ., Development. June 1, 2006; 133 (12): 2395-405.
Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. , He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.
PP2A:B56epsilon is required for eye induction and eye field separation. , Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM , Yang J ., Dev Biol. February 15, 2007; 302 (2): 477-93.
Correlation between Shh expression and DNA methylation status of the limb-specific Shh enhancer region during limb regeneration in amphibians. , Yakushiji N, Suzuki M , Satoh A , Sagai T, Shiroishi T, Kobayashi H, Sasaki H, Ide H , Tamura K , Tamura K ., Dev Biol. December 1, 2007; 312 (1): 171-82.
Effects of activation of hedgehog signaling on patterning, growth, and differentiation in Xenopus froglet limb regeneration. , Yakushiji N, Suzuki M , Satoh A , Ide H , Tamura K , Tamura K ., Dev Dyn. August 1, 2009; 238 (8): 1887-96.
Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. , Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M., Mech Dev. January 1, 2010; 127 (1-2): 62-72.
MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization. , Suzuki M , Hara Y, Takagi C, Yamamoto TS , Ueno N ., Development. July 1, 2010; 137 (14): 2329-39.
MIM regulates vertebrate neural tube closure. , Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R ., Development. May 1, 2011; 138 (10): 2035-47.
The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. , Min TH, Kriebel M, Hou S, Pera EM ., Dev Biol. October 1, 2011; 358 (1): 262-76.
The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1. , Jin Z, Mei W, Strack S, Jia J, Yang J ., J Biol Chem. October 21, 2011; 286 (42): 36171-9.
Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis. , Hasebe T , Kajita M, Fu L, Shi YB , Ishizuya-Oka A ., Dev Dyn. February 1, 2012; 241 (2): 403-14.
Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation. , Borday C, Cabochette P, Parain K , Mazurier N, Janssens S , Tran HT, Sekkali B, Bronchain O , Vleminckx K , Vleminckx K , Locker M , Perron M ., Development. October 1, 2012; 139 (19): 3499-509.
Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo. , Lobikin M, Chernet B , Lobo D, Levin M ., Phys Biol. December 1, 2012; 9 (6): 065002.
Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model. , Chernet BT , Levin M ., Dis Model Mech. May 1, 2013; 6 (3): 595-607.
The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with the transcription factor Gli1. , Martynova NY, Ermolina LV, Ermakova GV, Eroshkin FM, Gyoeva FK, Baturina NS, Zaraisky AG ., Dev Biol. August 1, 2013; 380 (1): 37-48.
Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling. , Nedelcu D, Liu J , Xu Y , Xu Y , Jao C, Salic A., Nat Chem Biol. September 1, 2013; 9 (9): 557-64.
Stabilization of speckle-type POZ protein ( Spop) by Daz interacting protein 1 ( Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling. , Schwend T , Jin Z, Jiang K, Mitchell BJ , Jia J, Yang J ., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.
Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. , Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R., Cell Rep. January 16, 2014; 6 (1): 168-81.