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Summary Expression Phenotypes Gene Literature (64) GO Terms (6) Nucleotides (60) Proteins (36) Interactants (299) Wiki
XB-GENEPAGE-943007

Papers associated with bcl2



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Hormonal regulation of programmed cell death during amphibian metamorphosis., Tata JR., Biochem Cell Biol. January 1, 1994; 72 (11-12): 581-8.

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria., Newmeyer DD, Farschon DM, Reed JC., Cell. October 21, 1994; 79 (2): 353-64.

Cloning, characterization and expression of two Xenopus bcl-2-like cell-survival genes., Cruz-Reyes J, Tata JR., Gene. June 9, 1995; 158 (2): 171-9.

Bcl-2 regulates activation of apoptotic proteases in a cell-free system., Cosulich SC, Green S, Clarke PR., Curr Biol. August 1, 1996; 6 (8): 997-1005.

Cleavage and inactivation of DNA-dependent protein kinase catalytic subunit during apoptosis in Xenopus egg extracts., Le Romancer M, Cosulich SC, Jackson SP, Clarke PR., J Cell Sci. December 1, 1996; 109 ( Pt 13) 3121-7.

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis., Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD., Science. February 21, 1997; 275 (5303): 1132-6.

Temporal phases in apoptosis defined by the actions of Src homology 2 domains, ceramide, Bcl-2, interleukin-1beta converting enzyme family proteases, and a dense membrane fraction., Farschon DM, Couture C, Mustelin T, Newmeyer DD., J Cell Biol. June 2, 1997; 137 (5): 1117-25.                    

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system., Kluck RM, Martin SJ, Hoffman BM, Zhou JS, Green DR, Newmeyer DD., EMBO J. August 1, 1997; 16 (15): 4639-49.

A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis., Faure S, Vigneron S, Dorée M, Morin N., EMBO J. September 15, 1997; 16 (18): 5550-61.

Zygotic transcription is required to block a maternal program of apoptosis in Xenopus embryos., Sible JC, Anderson JA, Lewellyn AL, Maller JL., Dev Biol. September 15, 1997; 189 (2): 335-46.

Cleavage of rabaptin-5 blocks endosome fusion during apoptosis., Cosulich SC, Horiuchi H, Zerial M, Clarke PR, Woodman PG., EMBO J. October 15, 1997; 16 (20): 6182-91.

A developmental timer that regulates apoptosis at the onset of gastrulation., Hensey C, Gautier J., Mech Dev. December 1, 1997; 69 (1-2): 183-95.          

Reaper-induced apoptosis in a vertebrate system., Evans EK, Kuwana T, Strum SL, Smith JJ, Newmeyer DD, Kornbluth S., EMBO J. December 15, 1997; 16 (24): 7372-81.

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development., Shibuya H, Iwata H, Masuyama N, Gotoh Y, Yamaguchi K, Irie K, Matsumoto K, Nishida E, Ueno N., EMBO J. February 16, 1998; 17 (4): 1019-28.

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c., Kuwana T, Smith JJ, Muzio M, Dixit V, Newmeyer DD, Kornbluth S., J Biol Chem. June 26, 1998; 273 (26): 16589-94.

Bcl-2 regulates amplification of caspase activation by cytochrome c., Cosulich SC, Savory PJ, Clarke PR., Curr Biol. February 11, 1999; 9 (3): 147-50.

Refolding, purification, and characterization of a loop deletion mutant of human Bcl-2 from bacterial inclusion bodies., Anderson M, Blowers D, Hewitt N, Hedge P, Breeze A, Hampton I, Taylor I., Protein Expr Purif. March 1, 1999; 15 (2): 162-70.

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol., Kluck RM, Esposti MD, Perkins G, Renken C, Kuwana T, Bossy-Wetzel E, Goldberg M, Allen T, Barber MJ, Green DR, Newmeyer DD., J Cell Biol. November 15, 1999; 147 (4): 809-22.                    

Overexpression of S-adenosylmethionine decarboxylase (SAMDC) activates the maternal program of apoptosis shortly after MBT in Xenopus embryos., Kai M, Higo T, Yokoska J, Kaito C, Kajita E, Fukamachi H, Takayama E, Igarashi K, Shiokawa K., Int J Dev Biol. August 1, 2000; 44 (5): 507-10.

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release., von Ahsen O, Renken C, Perkins G, Kluck RM, Bossy-Wetzel E, Newmeyer DD., J Cell Biol. September 4, 2000; 150 (5): 1027-36.                  

Cell cycle transitions in early Xenopus development., Maller JL, Gross SD, Schwab MS, Finkielstein CV, Taieb FE, Qian YW., Novartis Found Symp. January 1, 2001; 237 58-73; discussion 73-8.

The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage., Finkielstein CV, Lewellyn AL, Maller JL., Proc Natl Acad Sci U S A. January 30, 2001; 98 (3): 1006-11.            

Evidence for a role of the sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase in thapsigargin and Bcl-2 induced changes in Xenopus laevis oocyte maturation., Kobrinsky EM, Kirchberger MA., Oncogene. February 22, 2001; 20 (8): 933-41.

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper., Thress K, Song J, Morimoto RI, Kornbluth S., EMBO J. March 1, 2001; 20 (5): 1033-41.

Exogenous expression of mouse Dnmt3 induces apoptosis in Xenopus early embryos., Kimura H, Suetake I, Tajima S., J Biochem. June 1, 2002; 131 (6): 933-41.

Regulation of apoptosis in theXenopus embryo by Bix3., Trindade M, Messenger N, Papin C, Grimmer D, Fairclough L, Tada M, Smith JC., Development. October 1, 2003; 130 (19): 4611-22.                  

The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation., Van Stry M, McLaughlin KA, Ataliotis P, Symes K., Dev Biol. April 1, 2004; 268 (1): 232-42.          

A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest., Tríbulo C, Aybar MJ, Sánchez SS, Mayor R., Dev Biol. November 15, 2004; 275 (2): 325-42.

Involvement of caspase-9 in execution of the maternal program of apoptosis in Xenopus late blastulae overexpressed with S-adenosylmethionine decarboxylase., Takayama E, Higo T, Kai M, Fukasawa M, Nakajima K, Hara H, Tadakuma T, Igarashi K, Yaoita Y, Shiokawa K., Biochem Biophys Res Commun. December 24, 2004; 325 (4): 1367-75.              

The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells., Offner N, Duval N, Jamrich M, Durand B., Development. April 1, 2005; 132 (8): 1807-18.          

Occurrence of pre-MBT synthesis of caspase-8 mRNA and activation of caspase-8 prior to execution of SAMDC (S-adenosylmethionine decarboxylase)-induced, but not p53-induced, apoptosis in Xenopus late blastulae., Shiokawa K, Takayama E, Higo T, Kuroyanagi S, Kaito C, Hara H, Kajitani M, Sekimizu K, Tadakuma T, Miura K, Igarashi K, Yaoita Y., Biochem Biophys Res Commun. October 21, 2005; 336 (2): 682-91.              

Study of apoptosis in vitro using the Xenopus egg extract reconstitution system., Deming P, Kornbluth S., Methods Mol Biol. January 1, 2006; 322 379-93.

Mxi1 is essential for neurogenesis in Xenopus and acts by bridging the pan-neural and proneural genes., Klisch TJ, Souopgui J, Juergens K, Rust B, Pieler T, Henningfeld KA., Dev Biol. April 15, 2006; 292 (2): 470-85.                

The initiator caspase, caspase-10beta, and the BH-3-only molecule, Bid, demonstrate evolutionary conservation in Xenopus of their pro-apoptotic activities in the extrinsic and intrinsic pathways., Kominami K, Takagi C, Kurata T, Kitayama A, Nozaki M, Sawasaki T, Kuida K, Endo Y, Manabe N, Ueno N, Sakamaki K., Genes Cells. July 1, 2006; 11 (7): 701-17.

Developmental cell death during Xenopus metamorphosis involves BID cleavage and caspase 2 and 8 activation., Du Pasquier D, Rincheval V, Sinzelle L, Chesneau A, Ballagny C, Sachs LM, Demeneix B, Mazabraud A., Dev Dyn. August 1, 2006; 235 (8): 2083-94.                  

Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development., Wu J, O'Donnell M, Gitler AD, Klein PS., Development. September 1, 2006; 133 (18): 3651-60.          

tBid mediated activation of the mitochondrial death pathway leads to genetic ablation of the lens in Xenopus laevis., Du Pasquier D, Chesneau A, Ymlahi-Ouazzani Q, Boistel R, Pollet N, Ballagny C, Sachs LM, Demeneix B, Mazabraud A., Genesis. January 1, 2007; 45 (1): 1-10.            

Modulation of Nr-13 antideath activity by peptide aptamers., Nouvion AL, Thibaut J, Lohez OD, Venet S, Colas P, Gillet G, Lalle P., Oncogene. February 1, 2007; 26 (5): 701-10.

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak., Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM., J Cell Biol. April 23, 2007; 177 (2): 277-87.              

Signal transduction of fertilization in frog eggs and anti-apoptotic mechanism in human cancer cells: common and specific functions of membrane microdomains., Sato K., Open Biochem J. January 1, 2008; 2 49-59.        

Gene expression in Pre-MBT embryos and activation of maternally-inherited program of apoptosis to be executed at around MBT as a fail-safe mechanism in Xenopus early embryogenesis., Shiokawa K, Aso M, Kondo T, Uchiyama H, Kuroyanagi S, Takai J, Takahashi S, Kajitani M, Kaito C, Sekimizu K, Takayama E, Igarashi K, Hara H., Gene Regul Syst Bio. May 29, 2008; 2 213-31.                        

Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus., Nichane M, Ren X, Souopgui J, Bellefroid EJ., Dev Biol. October 15, 2008; 322 (2): 368-80.                        

A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification., Bonano M, Tríbulo C, De Calisto J, Marchant L, Sánchez SS, Mayor R, Aybar MJ., Dev Biol. November 1, 2008; 323 (1): 114-29.                          

High-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferases., Hida N, Awais M, Takeuchi M, Ueno N, Tashiro M, Takagi C, Singh T, Hayashi M, Ohmiya Y, Ozawa T., PLoS One. June 12, 2009; 4 (6): e5868.            

Pro-apoptotic activity and mono-/diubiquitylation of Xenopus Bid in egg extracts., Saitoh T, Tsuchiya Y, Kinoshita T, Itoh M, Yamashita S., Biochem Biophys Res Commun. July 10, 2009; 384 (4): 491-4.

p27(BBP)/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development., De Marco N, Iannone L, Carotenuto R, Biffo S, Vitale A, Campanella C., Cell Death Differ. February 1, 2010; 17 (2): 360-72.

In X. laevis embryos high levels of the anti-apoptotic factor p27BBP/eIF6 are stage-dependently found in BrdU and TUNEL-reactive territories., De Marco N, Campanella C, Carotenuto R., Zygote. May 1, 2011; 19 (2): 157-63.

Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis., Bugner V, Tecza A, Gessert S, Kühl M., Development. June 1, 2011; 138 (11): 2369-78.                        

Eukaryotic initiation factor 6 (eif6) overexpression affects eye development in Xenopus laevis., De Marco N, Tussellino M, Vitale A, Campanella C., Differentiation. September 1, 2011; 82 (2): 108-15.          

ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus., Tríbulo C, Guadalupe Barrionuevo M, Agüero TH, Sánchez SS, Calcaterra NB, Aybar MJ., Dev Dyn. February 1, 2012; 241 (2): 257-69.            

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