Papers associated with asic1

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	The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of the native FMRFamide peptide., Yang XN, Niu YY, Liu Y, Yang Y, Wang J, Cheng XY, Liang H, Wang HS, Hu YM, Lu XY, Zhu MX, Xu TL, Tian Y, Yu Y., J Biol Chem. December 29, 2017; 292 (52): 21662-21675.
	Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis., Osmakov DI, Koshelev SG, Andreev YA, Dubinnyi MA, Kublitski VS, Efremov RG, Sobolevsky AI, Kozlov SA., Br J Pharmacol. March 1, 2018; 175 (6): 924-937.
	The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel., Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Nörenberg W, Franke H, Gölöncsér F, Sperlágh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P., Nat Commun. April 10, 2018; 9 (1): 1354.
	Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity., Rayaprolu V, Royal P, Stengel K, Sandoz G, Kohout SC., J Gen Physiol. May 7, 2018; 150 (5): 683-696.
	Molecular basis of inhibition of acid sensing ion channel 1A by diminazene., Krauson AJ, Rooney JG, Carattino MD., PLoS One. May 15, 2018; 13 (5): e0196894.
	Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain., Lee JYP, Saez NJ, Cristofori-Armstrong B, Anangi R, King GF, Smith MT, Rash LD., Br J Pharmacol. June 1, 2018; 175 (12): 2204-2218.
	Inhalational anesthetics accelerate desensitization of acid-sensing ion channels., Lehmke L, Coburn M, Möller M, Blaumeiser-Debarry R, Lenzig P, Wiemuth D, Gründer S., Neuropharmacology. June 1, 2018; 135 496-505.
	New APETx-like peptides from sea anemone Heteractis crispa modulate ASIC1a channels., Kalina R, Gladkikh I, Dmitrenok P, Chernikov O, Koshelev S, Kvetkina A, Kozlov S, Kozlovskaya E, Monastyrnaya M., Peptides. June 1, 2018; 104 41-49.
	Functional features of the "finger" domain of the DEG/ENaC channels MEC-4 and UNC-8., Matthewman C, Johnson CK, Miller DM, Bianchi L., Am J Physiol Cell Physiol. August 1, 2018; 315 (2): C155-C163.
	The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain., Reiners M, Margreiter MA, Oslender-Bujotzek A, Rossetti G, Gründer S, Schmidt A., Mol Pharmacol. October 1, 2018; 94 (4): 1114-1124.
	Determinants of selective ion permeation in the epithelial Na+ channel., Yang L, Palmer LG., J Gen Physiol. October 1, 2018; 150 (10): 1397-1407.
	Thumb domains of the three epithelial Na+ channel subunits have distinct functions., Sheng S, Chen J, Mukherjee A, Yates ME, Buck TM, Brodsky JL, Tolino MA, Hughey RP, Kleyman TR., J Biol Chem. November 9, 2018; 293 (45): 17582-17592.
	Screening of 109 neuropeptides on ASICs reveals no direct agonists and dynorphin A, YFMRFamide and endomorphin-1 as modulators., Vyvers A, Schmidt A, Wiemuth D, Gründer S., Sci Rep. December 20, 2018; 8 (1): 18000.
	Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides., Bargeton B, Iwaszkiewicz J, Bonifacio G, Roy S, Zoete V, Kellenberger S., Sci Rep. February 22, 2019; 9 (1): 2599.
	Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands., Barth D, Fronius M., Sci Rep. May 1, 2019; 9 (1): 6781.
	The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues., Cristofori-Armstrong B, Saez NJ, Chassagnon IR, King GF, Rash LD., Biochem Pharmacol. May 1, 2019; 163 381-390.
	A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels., Wu Y, Chen Z, Canessa CM., Elife. May 2, 2019; 8
	Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system., Ilyaskin AV, Sure F, Nesterov V, Haerteis S, Korbmacher C., J Gen Physiol. June 3, 2019; 151 (6): 820-833.
	Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors., Florentino IF, Silva DPB, Cardoso CS, Menegatti R, de Carvalho FS, Lião LM, Pinto PM, Peigneur S, Costa EA, Tytgat J., Biomed Pharmacother. July 1, 2019; 115 108915.
	Multiple Modulation of Acid-Sensing Ion Channel 1a by the Alkaloid Daurisoline., Osmakov DI, Koshelev SG, Lyukmanova EN, Shulepko MA, Andreev YA, Illes P, Kozlov SA., Biomolecules. August 2, 2019; 9 (8):
	Alkaloid Lindoldhamine Inhibits Acid-Sensing Ion Channel 1a and Reveals Anti-Inflammatory Properties., Osmakov DI, Koshelev SG, Palikov VA, Palikova YA, Shaykhutdinova ER, Dyachenko IA, Andreev YA, Kozlov SA., Toxins (Basel). September 18, 2019; 11 (9):
	Mechanism and site of action of big dynorphin on ASIC1a., Borg CB, Braun N, Heusser SA, Bay Y, Weis D, Galleano I, Lund C, Tian W, Haugaard-Kedström LM, Bennett EP, Lynagh T, Strømgaard K, Andersen J, Pless SA., Proc Natl Acad Sci U S A. March 31, 2020; 117 (13): 7447-7454.
	APETx-Like Peptides from the Sea Anemone Heteractis crispa, Diverse in Their Effect on ASIC1a and ASIC3 Ion Channels., Kalina RS, Koshelev SG, Zelepuga EA, Kim NY, Kozlov SA, Kozlovskaya EP, Monastyrnaya MM, Gladkikh IN., Toxins (Basel). April 20, 2020; 12 (4):
	Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M, Shulepko M, Osmakov D, Andreev Y, Sudarikova A, Vasileva V, Pavlyukov MS, Latyshev YA, Potapov AA, Kirpichnikov M, Shenkarev ZO, Lyukmanova E., Cancers (Basel). July 8, 2020; 12 (7):
	Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a., Salinas M, Kessler P, Douguet D, Sarraf D, Tonali N, Thai R, Servent D, Lingueglia E., Neuropharmacology. March 1, 2021; 185 108453.
	The Neuropeptide Nocistatin Is Not a Direct Agonist of Acid-Sensing Ion Channel 1a (ASIC1a)., Kuspiel S, Wiemuth D, Gründer S., Biomolecules. April 13, 2021; 11 (4):
	Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket., Leisle L, Margreiter M, Ortega-Ramírez A, Cleuvers E, Bachmann M, Rossetti G, Gründer S., J Med Chem. September 23, 2021; 64 (18): 13299-13311.
	Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer., Sudarikova AV, Bychkov ML, Kulbatskii DS, Chubinskiy-Nadezhdin VI, Shlepova OV, Shulepko MA, Koshelev SG, Kirpichnikov MP, Lyukmanova EN., Front Oncol. January 1, 2022; 12 904742.
	Apamin structure and pharmacology revisited., Kuzmenkov AI, Peigneur S, Nasburg JA, Mineev KS, Nikolaev MV, Pinheiro-Junior EL, Arseniev AS, Wulff H, Tytgat J, Vassilevski AA., Front Pharmacol. January 1, 2022; 13 977440.
	A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels., Pinheiro-Junior EL, Kalina R, Gladkikh I, Leychenko E, Tytgat J, Peigneur S., Mar Drugs. February 17, 2022; 20 (2):
	Extracellular intersubunit interactions modulate epithelial Na+ channel gating., Zhang L, Wang X, Chen J, Sheng S, Kleyman TR., J Biol Chem. March 1, 2023; 299 (3): 102914.
	Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells., Lyukmanova EN, Zaigraev MM, Kulbatskii DS, Isaev AB, Kukushkin ID, Bychkov ML, Shulepko MA, Chugunov AO, Kirpichnikov MP., Toxins (Basel). October 13, 2023; 15 (10):

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