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Summary Expression Phenotypes Gene Literature (48) GO Terms (5) Nucleotides (91) Proteins (41) Interactants (470) Wiki
XB-GENEPAGE-485984

Papers associated with nkx2-1



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Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Lee J, Platt KA, Censullo P, Ruiz i Altaba A., Development. July 1, 1997; 124 (13): 2537-52.   


Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes., Small EM, Vokes SA, Garriock RJ, Li D, Krieg PA., Mech Dev. September 1, 2000; 96 (2): 259-62.   

Xnkx-2.1: a homeobox gene expressed during early forebrain, lung and thyroid development in Xenopus laevis., Hollemann T, Pieler T., Dev Genes Evol. November 1, 2000; 210 (11): 579-81.

Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes., Walters MJ, Wayman GA, Christian JL., Mech Dev. February 1, 2001; 100 (2): 263-73.

Regional expression of the homeobox gene NKX2-1 defines pallidal and interneuronal populations in the basal ganglia of amphibians., González A, López JM, Sánchez-Camacho C, Marín O., Neuroscience. January 1, 2002; 114 (3): 567-75.

Cititf1 and endoderm differentiation in Ciona intestinalis., Spagnuolo A, Di Lauro R., Gene. April 3, 2002; 287 (1-2): 115-9.

Expression pattern of the homeobox protein NKX2-1 in the developing Xenopus forebrain., González A, López JM, Marín O., Brain Res Gene Expr Patterns. October 1, 2002; 1 (3-4): 181-5.

Induction and patterning of the telencephalon in Xenopus laevis., Lupo G, Harris WA, Barsacchi G, Vignali R., Development. December 1, 2002; 129 (23): 5421-36.   


Expression of the genes Emx1, Tbr1, and Eomes (Tbr2) in the telencephalon of Xenopus laevis confirms the existence of a ventral pallial division in all tetrapods., Brox A, Puelles L, Ferreiro B, Medina L., J Comp Neurol. July 5, 2004; 474 (4): 562-77.   


Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning., Houston DW, Wylie C., Development. November 1, 2005; 132 (21): 4845-55.   


GABAergic specification in the basal forebrain is controlled by the LIM-hd factor Lhx7., Bachy I, Rétaux S., Dev Biol. March 15, 2006; 291 (2): 218-26.   


The role of early lineage in GABAergic and glutamatergic cell fate determination in Xenopus laevis., Li M, Sipe CW, Hoke K, August LL, Wright MA, Saha MS., J Comp Neurol. April 20, 2006; 495 (6): 645-57.   


Expression of sodium-iodide symporter mRNA in the thyroid gland of Xenopus laevis tadpoles: developmental expression, effects of antithyroidal compounds, and regulation by TSH., Opitz R, Trubiroha A, Lorenz C, Lutz I, Hartmann S, Blank T, Braunbeck T, Kloas W., J Endocrinol. July 1, 2006; 190 (1): 157-70.

Development of the vomeronasal amygdala in anuran amphibians: hodological, neurochemical, and gene expression characterization., Moreno N, González A., J Comp Neurol. August 20, 2007; 503 (6): 815-31.

Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution., van den Akker WM, Brox A, Puelles L, Durston AJ, Medina L., J Comp Neurol. January 10, 2008; 506 (2): 211-23.

Evidences for tangential migrations in Xenopus telencephalon: developmental patterns and cell tracking experiments., Moreno N, González A, Rétaux S., Dev Neurobiol. March 1, 2008; 68 (4): 504-20.   


Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus., Moreno N, Domínguez L, Rétaux S, González A., Neuroscience. July 17, 2008; 154 (4): 1423-39.

Spatio-temporal expression of Pax6 in Xenopus forebrain., Moreno N, Rétaux S, González A., Brain Res. November 6, 2008; 1239 92-9.   


FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation., Roth M, Bonev B, Lindsay J, Lea R, Panagiotaki N, Houart C, Papalopulu N., Development. May 1, 2010; 137 (9): 1553-62.   


Sonic hedgehog expression during Xenopus laevis forebrain development., Domínguez L, González A, Moreno N., Dev Biol. August 6, 2010; 1347 19-32.   


Ontogenetic distribution of the transcription factor nkx2.2 in the developing forebrain of Xenopus laevis., Domínguez L, González A, Moreno N., Front Neuroanat. March 2, 2011; 5 11.   


Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians., Moreno N, Morona R, López JM, Domínguez L, Joven A, Bandín S, González A., J Comp Neurol. February 1, 2012; 520 (2): 330-63.

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA, Rankin SA, Gallas AL, Neto A, Gómez-Skarmeta JL, Zorn AM., Development. August 1, 2012; 139 (16): 3010-20.   


Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.   


Characterization of the hypothalamus of Xenopus laevis during development. I. The alar regions., Domínguez L, Morona R, González A, Moreno N., J Comp Neurol. March 1, 2013; 521 (4): 725-59.   


Myb promotes centriole amplification and later steps of the multiciliogenesis program., Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA., Development. October 1, 2013; 140 (20): 4277-86.   


Lung epithelial branching program antagonizes alveolar differentiation., Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J., Proc Natl Acad Sci U S A. November 5, 2013; 110 (45): 18042-51.   


Regional expression of Pax7 in the brain of Xenopus laevis during embryonic and larval development., Bandín S, Morona R, Moreno N, González A., Front Neuroanat. December 24, 2013; 7 48.   


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.   


Characterization of the hypothalamus of Xenopus laevis during development. II. The basal regions., Domínguez L, González A, Moreno N., J Comp Neurol. April 1, 2014; 522 (5): 1102-31.   


Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

Patterns of hypothalamic regionalization in amphibians and reptiles: common traits revealed by a genoarchitectonic approach., Domínguez L, González A, Moreno N., Front Neuroanat. February 3, 2015; 9 3.   


At new heights - endodermal lineages in development and disease., Ober EA, Grapin-Botton A., Development. June 1, 2015; 142 (11): 1912-1917.   

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.   


Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Watanabe M, Yasuoka Y, Mawaribuchi S, Kuretani A, Ito M, Kondo M, Ochi H, Ogino H, Fukui A, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 301-324.   


Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.   


Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis., Gere-Becker MB, Pommerenke C, Lingner T, Pieler T., Development. June 8, 2018; 145 (12):   


RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus., Griffin JN, Sondalle SB, Robson A, Mis EK, Griffin G, Kulkarni SS, Deniz E, Baserga SJ, Khokha MK., Development. October 18, 2018; 145 (20):   


Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD, Rankin SA, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP., Proc Natl Acad Sci U S A. November 6, 2018; 115 (45): E10615-E10624.   


Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Nasr T, Mancini P, Rankin SA, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, Trisno SL, Cha SW, Wells JM, Kofron MJ, Zorn AM., Dev Cell. December 16, 2019; 51 (6): 665-674.e6.   


Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M., Horm Res Paediatr. January 1, 2020; 93 (1): 16-29.

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT, Willsey HR., Genesis. February 1, 2021; 59 (1-2): e23405.   


Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR, Exner CRT, Xu Y, Xu Y, Everitt A, Sun N, Wang B, Dea J, Schmunk G, Zaltsman Y, Teerikorpi N, Kim A, Anderson AS, Shin D, Seyler M, Nowakowski TJ, Harland RM, Willsey AJ, State MW., Neuron. March 3, 2021; 109 (5): 788-804.e8.

Identification of ZBTB26 as a Novel Risk Factor for Congenital Hypothyroidism., Vick P, Eberle B, Choukair D, Weiss B, Roeth R, Schneider I, Paramasivam N, Bettendorf M, Rappold GA., Genes (Basel). November 24, 2021; 12 (12):   


Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F, Liu H, Fechtner L, Neuhaus H, Ding J, Arlt D, Walentek P, Villavicencio-Lorini P, Gerhardt C, Hollemann T, Pfirrmann T., J Cell Sci. May 1, 2022; 135 (9):   


Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):   


The homeodomain transcription factor Ventx2 regulates respiratory progenitor cell number and differentiation timing during Xenopus lung development., Rankin SA, Rankin SA, Zorn AM., Dev Growth Differ. September 1, 2022; 64 (7): 347-361.   

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