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Summary Expression Phenotypes Gene Literature (65) GO Terms (76) Nucleotides (91) Proteins (41) Interactants (586) Wiki
XB-GENEPAGE-485984

Papers associated with nkx2-1



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Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Lee J, Platt KA, Censullo P, Ruiz i Altaba A., Development. July 1, 1997; 124 (13): 2537-52.   


Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes., Small EM, Vokes SA, Garriock RJ, Li D, Krieg PA., Mech Dev. September 1, 2000; 96 (2): 259-62.   

Xnkx-2.1: a homeobox gene expressed during early forebrain, lung and thyroid development in Xenopus laevis., Hollemann T, Pieler T., Dev Genes Evol. November 1, 2000; 210 (11): 579-81.

Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes., Walters MJ, Wayman GA, Christian JL., Mech Dev. February 1, 2001; 100 (2): 263-73.

Regional expression of the homeobox gene NKX2-1 defines pallidal and interneuronal populations in the basal ganglia of amphibians., González A, López JM, Sánchez-Camacho C, Marín O., Neuroscience. January 1, 2002; 114 (3): 567-75.

Cititf1 and endoderm differentiation in Ciona intestinalis., Spagnuolo A, Di Lauro R., Gene. April 3, 2002; 287 (1-2): 115-9.

Defining pallial and subpallial divisions in the developing Xenopus forebrain., Bachy I, Berthon J, Rétaux S., Mech Dev. September 1, 2002; 117 (1-2): 163-72.   


Expression pattern of the homeobox protein NKX2-1 in the developing Xenopus forebrain., González A, López JM, Marín O., Brain Res Gene Expr Patterns. October 1, 2002; 1 (3-4): 181-5.

Induction and patterning of the telencephalon in Xenopus laevis., Lupo G, Harris WA, Barsacchi G, Vignali R., Development. December 1, 2002; 129 (23): 5421-36.   


Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos., Galli A, Roure A, Zeller R, Dono R., Development. October 1, 2003; 130 (20): 4919-29.   


Expression of the genes Emx1, Tbr1, and Eomes (Tbr2) in the telencephalon of Xenopus laevis confirms the existence of a ventral pallial division in all tetrapods., Brox A, Puelles L, Ferreiro B, Medina L., J Comp Neurol. July 5, 2004; 474 (4): 562-77.   


Xenopus laevis FoxE1 is primarily expressed in the developing pituitary and thyroid., El-Hodiri HM, Seufert DW, Nekkalapudi S, Prescott NL, Kelly LE, Jamrich M., Int J Dev Biol. January 1, 2005; 49 (7): 881-4.   


Xenopus aristaless-related homeobox (xARX) gene product functions as both a transcriptional activator and repressor in forebrain development., Seufert DW, Prescott NL, El-Hodiri HM., Dev Dyn. February 1, 2005; 232 (2): 313-24.   


Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning., Houston DW, Wylie C., Development. November 1, 2005; 132 (21): 4845-55.   


Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation., Wills A, Harland RM, Khokha MK., Dev Biol. January 1, 2006; 289 (1): 166-78.   


Role of X-Delta-2 in the early neural development of Xenopus laevis., Peres JN, Durston AJ., Dev Dyn. March 1, 2006; 235 (3): 802-10.   


GABAergic specification in the basal forebrain is controlled by the LIM-hd factor Lhx7., Bachy I, Rétaux S., Dev Biol. March 15, 2006; 291 (2): 218-26.   


The role of early lineage in GABAergic and glutamatergic cell fate determination in Xenopus laevis., Li M, Sipe CW, Hoke K, August LL, Wright MA, Saha MS., J Comp Neurol. April 20, 2006; 495 (6): 645-57.   


Expression of sodium-iodide symporter mRNA in the thyroid gland of Xenopus laevis tadpoles: developmental expression, effects of antithyroidal compounds, and regulation by TSH., Opitz R, Trubiroha A, Lorenz C, Lutz I, Hartmann S, Blank T, Braunbeck T, Kloas W., J Endocrinol. July 1, 2006; 190 (1): 157-70.

Lung specific developmental expression of the Xenopus laevis surfactant protein C and B genes., Hyatt BA, Resnik ER, Johnson NS, Lohr JL, Cornfield DN., Gene Expr Patterns. January 1, 2007; 7 (1-2): 8-14.   


Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development., McLin VA, Rankin SA, Zorn AM., Development. June 1, 2007; 134 (12): 2207-17.   


Development of the vomeronasal amygdala in anuran amphibians: hodological, neurochemical, and gene expression characterization., Moreno N, González A., J Comp Neurol. August 20, 2007; 503 (6): 815-31.

Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution., van den Akker WM, Brox A, Puelles L, Durston AJ, Medina L., J Comp Neurol. January 10, 2008; 506 (2): 211-23.

Evidences for tangential migrations in Xenopus telencephalon: developmental patterns and cell tracking experiments., Moreno N, González A, Rétaux S., Dev Neurobiol. March 1, 2008; 68 (4): 504-20.   


Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus., Moreno N, Domínguez L, Rétaux S, González A., Neuroscience. July 17, 2008; 154 (4): 1423-39.

Spatio-temporal expression of Pax6 in Xenopus forebrain., Moreno N, Rétaux S, González A., Brain Res. November 6, 2008; 1239 92-9.   


Comparative expression analysis of the neurogenins in Xenopus tropicalis and Xenopus laevis., Nieber F, Pieler T, Henningfeld KA., Dev Dyn. February 1, 2009; 238 (2): 451-8.   


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus., Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM., Dev Biol. January 15, 2010; 337 (2): 335-50.   


FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation., Roth M, Bonev B, Lindsay J, Lea R, Panagiotaki N, Houart C, Papalopulu N., Development. May 1, 2010; 137 (9): 1553-62.   


Sonic hedgehog expression during Xenopus laevis forebrain development., Domínguez L, González A, Moreno N., Dev Biol. August 6, 2010; 1347 19-32.   


Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis., Wang JH, Deimling SJ, D'Alessandro NE, Zhao L, Possmayer F, Drysdale TA., BMC Dev Biol. January 26, 2011; 11 75.   


Ontogenetic distribution of the transcription factor nkx2.2 in the developing forebrain of Xenopus laevis., Domínguez L, González A, Moreno N., Front Neuroanat. March 2, 2011; 5 11.   


Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians., Moreno N, Morona R, López JM, Domínguez L, Joven A, Bandín S, González A., J Comp Neurol. February 1, 2012; 520 (2): 330-63.

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA, Rankin SA, Gallas AL, Neto A, Gómez-Skarmeta JL, Zorn AM., Development. August 12, 2012; 139 (16): 3010-20.   


Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.   


The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.   


Characterization of the hypothalamus of Xenopus laevis during development. I. The alar regions., Domínguez L, Morona R, González A, Moreno N., J Comp Neurol. March 1, 2013; 521 (4): 725-59.   


Myb promotes centriole amplification and later steps of the multiciliogenesis program., Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA., Development. October 1, 2013; 140 (20): 4277-86.   


Lung epithelial branching program antagonizes alveolar differentiation., Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J., Proc Natl Acad Sci U S A. November 5, 2013; 110 (45): 18042-51.   


Regional expression of Pax7 in the brain of Xenopus laevis during embryonic and larval development., Bandín S, Morona R, Moreno N, González A., Front Neuroanat. December 24, 2013; 7 48.   


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.   


Characterization of the hypothalamus of Xenopus laevis during development. II. The basal regions., Domínguez L, González A, Moreno N., J Comp Neurol. April 1, 2014; 522 (5): 1102-31.   


Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.   


A Molecular atlas of Xenopus respiratory system development., Rankin SA, Rankin SA, Thi Tran H, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Vleminckx K, Wert SE, Zorn AM., Dev Dyn. January 1, 2015; 244 (1): 69-85.   


Patterns of hypothalamic regionalization in amphibians and reptiles: common traits revealed by a genoarchitectonic approach., Domínguez L, González A, Moreno N., Front Neuroanat. February 3, 2015; 9 3.   


RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development., Pfirrmann T, Villavicencio-Lorini P, Subudhi AK, Menssen R, Wolf DH, Hollemann T., PLoS One. March 16, 2015; 10 (3): e0120342.   


At new heights - endodermal lineages in development and disease., Ober EA, Grapin-Botton A., Development. June 1, 2015; 142 (11): 1912-1917.   

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.   


Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.   

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