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Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2. , Paris J, Le Guellec R, Couturier A, Le Guellec K, Omilli F, Camonis J, MacNeill S, Philippe M., Proc Natl Acad Sci U S A. February 1, 1991; 88 (3): 1039-43.
Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein. , Le Guellec R, Paris J, Couturier A, Roghi C, Philippe M., Mol Cell Biol. June 1, 1991; 11 (6): 3395-8.
A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1. , Elledge SJ, Spottswood MR., EMBO J. September 1, 1991; 10 (9): 2653-9.
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. , Tsai LH, Harlow E, Meyerson M., Nature. September 12, 1991; 353 (6340): 174-7.
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. , Koff A, Cross F, Fisher A, Schumacher J, Leguellec K, Philippe M, Roberts JM., Cell. September 20, 1991; 66 (6): 1217-28.
Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. , Ninomiya-Tsuji J, Nomoto S, Yasuda H, Reed SI, Matsumoto K ., Proc Natl Acad Sci U S A. October 15, 1991; 88 (20): 9006-10.
A cdc2-related kinase oscillates in the cell cycle independently of cyclins G2/M and cdc2. , Gabrielli BG, Roy LM, Gautier J , Philippe M, Maller JL ., J Biol Chem. January 25, 1992; 267 (3): 1969-75.
CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle. , Elledge SJ, Richman R, Hall FL, Williams RT, Lodgson N, Harper JW., Proc Natl Acad Sci U S A. April 1, 1992; 89 (7): 2907-11.
Isolation and characterization of goldfish cdk2, a cognate variant of the cell cycle regulator cdc2. , Hirai T, Yamashita M , Yoshikuni M, Tokumoto T, Kajiura H, Sakai N, Nagahama Y., Dev Biol. July 1, 1992; 152 (1): 113-20.
Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2. , Devault A, Fesquet D, Cavadore JC, Garrigues AM, Labbé JC, Lorca T, Picard A, Philippe M, Dorée M., J Cell Biol. September 1, 1992; 118 (5): 1109-20.
Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex. , Gabrielli BG, Lee MS, Walker DH, Piwnica-Worms H, Maller JL ., J Biol Chem. September 5, 1992; 267 (25): 18040-6.
Phosphorylation independent activation of human cyclin-dependent kinase 2 by cyclin A in vitro. , Connell-Crowley L, Solomon MJ , Wei N, Harper JW., Mol Biol Cell. January 1, 1993; 4 (1): 79-92.
Requirement for Cdk2 in cytostatic factor-mediated metaphase II arrest. , Gabrielli BG, Roy LM, Maller JL ., Science. March 19, 1993; 259 (5102): 1766-9.
Cloning of the Eh cdc2 gene from Entamoeba histolytica encoding a protein kinase p34cdc2 homologue. , Lohia A, Samuelson J., Gene. May 30, 1993; 127 (2): 203-7.
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues. , Fesquet D, Labbé JC, Derancourt J, Capony JP, Galas S, Girard F, Lorca T, Shuttleworth J, Dorée M, Cavadore JC., EMBO J. August 1, 1993; 12 (8): 3111-21.
Distinct roles of cdk2 and cdc2 in RP-A phosphorylation during the cell cycle. , Fang F, Newport JW., J Cell Sci. November 1, 1993; 106 ( Pt 3) 983-94.
Molecular cloning and identification of two types of hamster cyclin-dependent kinases: cdk2 and cdk2L. , Noguchi E, Sekiguchi T, Yamashita K, Nishimoto T., Biochem Biophys Res Commun. December 30, 1993; 197 (3): 1524-9.
Study of the higher eukaryotic gene function CDK2 using fission yeast. , Paris J, Leplatois P, Nurse P., J Cell Sci. March 1, 1994; 107 ( Pt 3) 615-23.
Molecular cloning of the human CAK1 gene encoding a cyclin-dependent kinase-activating kinase. , Wu L, Yee A, Liu L, Carbonaro-Hall D, Venkatesan N, Tolo VT, Hall FL., Oncogene. July 1, 1994; 9 (7): 2089-96.
E2F and its developmental regulation in Xenopus laevis. , Philpott A , Friend SH., Mol Cell Biol. July 1, 1994; 14 (7): 5000-9.
Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts. , Adachi Y, Laemmli UK., EMBO J. September 1, 1994; 13 (17): 4153-64.
Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development. , Stebbins-Boaz B, Richter JD., Mol Cell Biol. September 1, 1994; 14 (9): 5870-80.
Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15. , Poon RY, Yamashita K, Howell M, Ershler MA, Belyavsky A, Hunt T ., J Cell Sci. October 1, 1994; 107 ( Pt 10) 2789-99.
Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. , Strausfeld UP, Howell M, Rempel R, Maller JL , Hunt T , Blow JJ ., Curr Biol. October 1, 1994; 4 (10): 876-83.
Activation of cyclin-dependent kinase 4 ( cdk4) by mouse MO15-associated kinase. , Matsuoka M, Kato JY, Fisher RP, Morgan DO, Sherr CJ., Mol Cell Biol. November 1, 1994; 14 (11): 7265-75.
Cloning of the Xenopus laevis cdk2 promoter and functional analysis in oocytes and during early development. , Olive M, Thézé N , Philippe M, Le Pennec JP, Lerivray H., Gene. December 30, 1994; 151 (1-2): 81-8.
Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases. , Abraham RT, Acquarone M, Andersen A, Asensi A, Bellé R, Berger F, Bergounioux C, Brunn G, Buquet-Fagot C, Fagot D., Biol Cell. January 1, 1995; 83 (2-3): 105-20.
Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity. , Izumi T, Maller JL ., Mol Biol Cell. February 1, 1995; 6 (2): 215-26.
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. , Chen J , Jackson PK , Kirschner MW , Dutta A ., Nature. March 23, 1995; 374 (6520): 386-8.
Maternal Xenopus Cdk2-cyclin E complexes function during meiotic and early embryonic cell cycles that lack a G1 phase. , Rempel RE, Sleight SB, Maller JL ., J Biol Chem. March 24, 1995; 270 (12): 6843-55.
An analysis of the regulation of DNA synthesis by cdk2, Cip1, and licensing factor. , Yan H, Newport J., J Cell Biol. April 1, 1995; 129 (1): 1-15.
Both cdc2 and cdk2 promote S phase initiation in Xenopus egg extracts. , Chevalier S, Tassan JP , Cox R, Philippe M, Ford C., J Cell Sci. May 1, 1995; 108 ( Pt 5) 1831-41.
Molecular cloning and immunological analysis of goldfish cyclin A during oocyte maturation. , Katsu Y, Yamashita M , Hirai T, Tokumoto T, Kajiura H, Nagahama Y., Dev Biol. August 1, 1995; 170 (2): 616-25.
Early events in DNA replication require cyclin E and are blocked by p21CIP1. , Jackson PK , Chevalier S, Philippe M, Kirschner MW ., J Cell Biol. August 1, 1995; 130 (4): 755-69.
Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1. , Su JY, Rempel RE, Erikson E, Maller JL ., Proc Natl Acad Sci U S A. October 24, 1995; 92 (22): 10187-91.
Identification of a cdk-activating kinase in fission yeast. , Buck V, Russell P, Millar JB., EMBO J. December 15, 1995; 14 (24): 6173-83.
Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2- cyclin B kinase activity. , Guadagno TM, Newport JW., Cell. January 12, 1996; 84 (1): 73-82.
In vivo regulation of the early embryonic cell cycle in Xenopus. , Hartley RS , Rempel RE, Maller JL ., Dev Biol. February 1, 1996; 173 (2): 408-19.
Cell cycle control by Xenopus p28Kix1, a developmentally regulated inhibitor of cyclin-dependent kinases. , Shou W, Dunphy WG ., Mol Biol Cell. March 1, 1996; 7 (3): 457-69.
CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c- mos mRNAs and is necessary for oocyte maturation in Xenopus. , Stebbins-Boaz B, Hake LE , Richter JD., EMBO J. May 15, 1996; 15 (10): 2582-92.
Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts. , Strausfeld UP, Howell M, Descombes P, Chevalier S, Rempel RE, Adamczewski J, Maller JL , Hunt T , Blow JJ ., J Cell Sci. June 1, 1996; 109 ( Pt 6) 1555-63.
Xenopus cyclin E, a nuclear phosphoprotein, accumulates when oocytes gain the ability to initiate DNA replication. , Chevalier S, Couturier A, Chartrain I, Le Guellec R, Beckhelling C, Le Guellec K, Philippe M, Ford CC ., J Cell Sci. June 1, 1996; 109 ( Pt 6) 1173-84.
Nuclear proteins of quiescent Xenopus laevis cells inhibit DNA replication in intact and permeabilized nuclei. , Fang J, Benbow RM., J Cell Biol. June 1, 1996; 133 (5): 955-69.
Cyclin-binding motifs are essential for the function of p21CIP1. , Chen J , Saha P, Kornbluth S , Dynlacht BD, Dutta A ., Mol Cell Biol. September 1, 1996; 16 (9): 4673-82.
A predictive scale for evaluating cyclin-dependent kinase substrates. A comparison of p34cdc2 and p33cdk2. , Holmes JK, Solomon MJ ., J Biol Chem. October 11, 1996; 271 (41): 25240-6.
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. , Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ , Inagaki N, Inagaki M, Delcros JG, Moulinoux JP., Eur J Biochem. January 15, 1997; 243 (1-2): 527-36.
Identification of functional domains in the neuronal Cdk5 activator protein. , Poon RY, Lew J, Hunter T., J Biol Chem. February 28, 1997; 272 (9): 5703-8.
Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines. , Yang R, Morosetti R, Koeffler HP., Cancer Res. March 1, 1997; 57 (5): 913-20.
A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. , Hua XH, Yan H, Newport J., J Cell Biol. April 7, 1997; 137 (1): 183-92.
Ionizing radiation induces apoptosis and elevates cyclin A1- Cdk2 activity before but not after the midblastula transition in Xenopus. , Anderson JA, Lewellyn AL, Maller JL ., Mol Biol Cell. July 1, 1997; 8 (7): 1195-206.