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Summary Expression Phenotypes Gene Literature (78) GO Terms (11) Nucleotides (272) Proteins (82) Interactants (728) Wiki
XB-GENEPAGE-952298

Papers associated with ppp3ca



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Critical contribution of the intracellular C-terminal region to TRESK channel activity is revealed by the epithelial Na+ current ratio method., Debreczeni D, Baukál D, Pergel E, Veres I, Czirják G., J Biol Chem. June 1, 2023; 299 (6): 104737.                        

RedoxiFluor: A microplate technique to quantify target-specific protein thiol redox state in relative percentage and molar terms., Tuncay A, Noble A, Guille M, Cobley JN., Free Radic Biol Med. March 1, 2022; 181 118-129.

KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity., Pavinato L, Nematian-Ardestani E, Zonta A, De Rubeis S, Buxbaum J, Mancini C, Bruselles A, Tartaglia M, Pessia M, Tucker SJ, D'Adamo MC, Brusco A., Int J Mol Sci. June 4, 2021; 22 (11):         

TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons., Lengyel M, Czirják G, Jacobson DA, Enyedi P., J Biol Chem. August 28, 2020; 295 (35): 12408-12425.                      

Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability., Imbrici P, Nematian-Ardestani E, Hasan S, Pessia M, Tucker SJ, D'Adamo MC., Pflugers Arch. July 1, 2020; 472 (7): 923-930.

Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K2P18.1) Background Potassium Channel., Lengyel M, Erdélyi F, Pergel E, Bálint-Polonka Á, Dobolyi A, Bozsaki P, Dux M, Király K, Hegedűs T, Czirják G, Mátyus P, Enyedi P., Mol Pharmacol. June 1, 2019; 95 (6): 652-660.

TRESK (K2P18.1) Background Potassium Channel Is Activated by Novel-Type Protein Kinase C via Dephosphorylation., Pergel E, Lengyel M, Enyedi P, Czirják G., Mol Pharmacol. June 1, 2019; 95 (6): 661-672.

Calcineurin-dependent Protein Phosphorylation Changes During Egg Activation in Drosophila melanogaster., Zhang Z, Ahmed-Braimah YH, Goldberg ML, Wolfner MF., Mol Cell Proteomics. March 15, 2019; 18 (Suppl 1): S145-S158.

Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20., Heim A, Tischer T, Mayer TU., EMBO Rep. December 1, 2018; 19 (12):


Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function., Wahl SE, Wyatt BH, Turner SD, Dickinson AJG., BMC Genomics. November 3, 2018; 19 (1): 795.              

Modulation of Cl- signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT., Vachel L, Shcheynikov N, Yamazaki O, Fremder M, Ohana E, Son A, Shin DM, Yamazaki-Nakazawa A, Yang CR, Knepper MA, Muallem S., Sci Signal. October 30, 2018; 11 (554):


Regulation of nuclear factor of activated T cells (NFAT) and downstream myogenic proteins during dehydration in the African clawed frog., Zhang Y, English SG, Storey KB., Mol Biol Rep. October 1, 2018; 45 (5): 751-761.

Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel., Rokic MB, Castro P, Leiva-Salcedo E, Tomic M, Stojilkovic SS, Coddou C., Int J Mol Sci. April 11, 2018; 19 (4):                     

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis., Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X., Nat Commun. June 7, 2017; 8 15279.              

The Kinase CIPK23 Inhibits Ammonium Transport in Arabidopsis thaliana., Straub T, Ludewig U, Neuhäuser B., Plant Cell. February 1, 2017; 29 (2): 409-422.

Properties, regulation, pharmacology, and functions of the K₂p channel, TRESK., Enyedi P, Czirják G., Pflugers Arch. May 1, 2015; 467 (5): 945-58.

Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling., Kollert S, Dombert B, Döring F, Wischmeyer E., Sci Rep. January 12, 2015; 5 12548.            

Site- and kinase-specific phosphorylation-mediated activation of SLAC1, a guard cell anion channel stimulated by abscisic acid., Maierhofer T, Diekmann M, Offenborn JN, Lind C, Bauer H, Hashimoto K, S Al-Rasheid KA, Luan S, Kudla J, Geiger D, Hedrich R., Sci Signal. September 9, 2014; 7 (342): ra86.

The Xenopus alcohol dehydrogenase gene family: characterization and comparative analysis incorporating amphibian and reptilian genomes., Borràs E, Albalat R, Duester G, Parés X, Farrés J., BMC Genomics. March 20, 2014; 15 216.          

Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters., Ho CH, Frommer WB., Elife. March 12, 2014; 3 e01917.                

Phosphorylation-mediated stabilization of Bora in mitosis coordinates Plx1/Plk1 and Cdk1 oscillations., Feine O, Hukasova E, Bruinsma W, Freire R, Fainsod A, Gannon J, Mahbubani HM, Lindqvist A, Brandeis M., Cell Cycle. January 1, 2014; 13 (11): 1727-36.

Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Vandenberg LN, Blackiston DJ, Rea AC, Dore TM, Levin M., Int J Dev Biol. January 1, 2014; 58 (10-12): 799-809.                

Calcineurin B-like protein CBL10 directly interacts with AKT1 and modulates K+ homeostasis in Arabidopsis., Ren XL, Qi GN, Feng HQ, Zhao S, Zhao SS, Wang Y, Wu WH., Plant J. April 1, 2013; 74 (2): 258-66.

PKC-dependent activation of human K(2P) 18.1 K(+) channels., Rahm AK, Gierten J, Kisselbach J, Staudacher I, Staudacher K, Schweizer PA, Becker R, Katus HA, Thomas D., Br J Pharmacol. May 1, 2012; 166 (2): 764-73.

Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis., Takeo S, Swanson SK, Nandanan K, Nakai Y, Aigaki T, Washburn MP, Florens L, Hawley RS., Proc Natl Acad Sci U S A. April 24, 2012; 109 (17): 6382-9.

Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during the Xenopus laevis oocyte to embryo transition., Marteil G, Gagné JP, Borsuk E, Richard-Parpaillon L, Poirier GG, Kubiak JZ., Int J Biochem Cell Biol. January 1, 2012; 44 (1): 53-64.

Evolution of vertebrate central nervous system is accompanied by novel expression changes of duplicate genes., Chen Y, Chen Y, Ding Y, Zhang Z, Wang W, Chen JY, Ueno N, Mao B., J Genet Genomics. December 20, 2011; 38 (12): 577-84.                                                                                                                                                          

Mechanistic analysis of AKT1 regulation by the CBL-CIPK-PP2CA interactions., Lan WZ, Lee SC, Che YF, Jiang YQ, Luan S., Mol Plant. May 1, 2011; 4 (3): 527-36.

Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B., Bergeron MJ, Bürzle M, Kovacs G, Simonin A, Hediger MA., J Biol Chem. April 1, 2011; 286 (13): 11242-53.

RCAN1 regulates vascular branching during Xenopus laevis angiogenesis., Fujiwara M, Hasebe T, Kajita M, Ishizuya-Oka A, Ghazizadeh M, Kawanami O., J Vasc Res. January 1, 2011; 48 (2): 104-18.

TRESK background K(+) channel is inhibited by PAR-1/MARK microtubule affinity-regulating kinases in Xenopus oocytes., Braun G, Nemcsics B, Enyedi P, Czirják G., PLoS One. January 1, 2011; 6 (12): e28119.            

Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase., Suzuki T, Suzuki E, Yoshida N, Kubo A, Li H, Okuda E, Amanai M, Perry AC., Development. October 1, 2010; 137 (19): 3281-91.            

Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs., Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD., PLoS One. August 5, 2010; 5 (8): e11925.                

TRESK background K(+) channel is inhibited by phosphorylation via two distinct pathways., Czirjak G, Enyedi P., J Biol Chem. May 7, 2010; 285 (19): 14549-57.

Light modulates the melanophore response to alpha-MSH in Xenopus laevis: an analysis of the signal transduction crosstalk mechanisms involved., Isoldi MC, Provencio I, Castrucci AM., Gen Comp Endocrinol. January 1, 2010; 165 (1): 104-10.          

A grapevine Shaker inward K(+) channel activated by the calcineurin B-like calcium sensor 1-protein kinase CIPK23 network is expressed in grape berries under drought stress conditions., Cuéllar T, Pascaud F, Verdeil JL, Torregrosa L, Adam-Blondon AF, Thibaud JB, Sentenac H, Gaillard I., Plant J. January 1, 2010; 61 (1): 58-69.

Potassium channels in barley: cloning, functional characterization and expression analyses in relation to leaf growth and development., Boscari A, Clément M, Volkov V, Golldack D, Hybiak J, Miller AJ, Amtmann A, Fricke W., Plant Cell Environ. December 1, 2009; 32 (12): 1761-77.

Neural activity regulates synaptic properties and dendritic structure in vivo through calcineurin/NFAT signaling., Schwartz N, Schohl A, Ruthazer ES., Neuron. June 11, 2009; 62 (5): 655-69.

Mitochondria and calcium signaling in embryonic development., Cao X, Chen Y., Semin Cell Dev Biol. May 1, 2009; 20 (3): 337-45.    

Caenorhabditis elegans glutamate transporter deletion induces AMPA-receptor/adenylyl cyclase 9-dependent excitotoxicity., Mano I, Driscoll M., J Neurochem. March 1, 2009; 108 (6): 1373-84.

Phosphorylation-dependent binding of 14-3-3 proteins controls TRESK regulation., Czirják G, Vuity D, Enyedi P., J Biol Chem. June 6, 2008; 283 (23): 15672-80.

Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis., Nishiyama T, Yoshizaki N, Kishimoto T, Ohsumi K., Nature. September 20, 2007; 449 (7160): 341-5.

Calcineurin is required to release Xenopus egg extracts from meiotic M phase., Mochida S, Hunt T., Nature. September 20, 2007; 449 (7160): 336-40.

The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis., Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X., Mol Cell Biol. September 1, 2007; 27 (18): 6420-32.

BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin., Wen Z, Han L, Bamburg JR, Shim S, Ming GL, Zheng JQ., J Cell Biol. July 2, 2007; 178 (1): 107-19.                    

CDK1 and calcineurin regulate Maskin association with eIF4E and translational control of cell cycle progression., Cao Q, Kim JH, Richter JD., Nat Struct Mol Biol. December 1, 2006; 13 (12): 1128-34.

Involvement of p120 catenin in myopodial assembly and nerve-muscle synapse formation., Madhavan R, Zhao XT, Reynolds AB, Peng HB., J Neurobiol. November 1, 2006; 66 (13): 1511-27.                

A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis., Xu J, Li HD, Chen LQ, Wang Y, Liu LL, He L, Wu WH., Cell. June 30, 2006; 125 (7): 1347-60.

Targeting of calcineurin to an NFAT-like docking site is required for the calcium-dependent activation of the background K+ channel, TRESK., Czirják G, Enyedi P., J Biol Chem. May 26, 2006; 281 (21): 14677-82.

XNF-ATc3 affects neural convergent extension., Borchers A, Fonar Y, Frank D, Baker JC., Development. May 1, 2006; 133 (9): 1745-55.          

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