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Summary Expression Phenotypes Gene Literature (200) GO Terms (6) Nucleotides (59) Proteins (39) Interactants (186) Wiki
XB-GENEPAGE-483959

Papers associated with kcnj1



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An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis., Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP., Proc Natl Acad Sci U S A. March 6, 2007; 104 (10): 4025-9.

Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels., Chang HK, Yeh SH, Shieh RC., J Membr Biol. February 1, 2007; 215 (2-3): 181-93.

Moving the pH gate of the Kir1.1 inward rectifier channel., Nanazashvili M, Li H, Palmer LG, Walters DE, Sackin H., Channels (Austin). January 1, 2007; 1 (1): 21-8.

Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved., Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, Cuthbert AW, O'shaughnessy KM., Am J Physiol Renal Physiol. December 1, 2006; 291 (6): F1369-76.

Localization of the pH gate in Kir1.1 channels., Zhang YY, Sackin H, Palmer LG., Biophys J. October 15, 2006; 91 (8): 2901-9.

WNK1 affects surface expression of the ROMK potassium channel independent of WNK4., Cope G, Murthy M, Golbang AP, Hamad A, Liu CH, Cuthbert AW, O'Shaughnessy KM., J Am Soc Nephrol. July 1, 2006; 17 (7): 1867-74.

Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel., Rapedius M, Haider S, Browne KF, Shang L, Sansom MS, Baukrowitz T, Tucker SJ., EMBO Rep. June 1, 2006; 7 (6): 611-6.

Role of conserved glycines in pH gating of Kir1.1 (ROMK)., Sackin H, Nanazashvili M, Palmer LG, Li H., Biophys J. May 15, 2006; 90 (10): 3582-9.

CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney., Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC., J Clin Invest. March 1, 2006; 116 (3): 797-807.

WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1)., Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC., J Physiol. March 1, 2006; 571 (Pt 2): 275-86.

Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanism., Leng Q, MacGregor GG, Dong K, Giebisch G, Hebert SC., Proc Natl Acad Sci U S A. February 7, 2006; 103 (6): 1982-7.

Involvement of Golgin-160 in cell surface transport of renal ROMK channel: co-expression of Golgin-160 increases ROMK currents., Bundis F, Neagoe I, Schwappach B, Steinmeyer K., Cell Physiol Biochem. January 1, 2006; 17 (1-2): 1-12.

Electrostatics in the cytoplasmic pore produce intrinsic inward rectification in kir2.1 channels., Yeh SH, Chang HK, Shieh RC., J Gen Physiol. December 1, 2005; 126 (6): 551-62.                    

Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels., Xie LH, John SA, Ribalet B, Weiss JN., J Gen Physiol. December 1, 2005; 126 (6): 541-9.              

A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal., Yoo D, Fang L, Mason A, Kim BY, Welling PA., J Biol Chem. October 21, 2005; 280 (42): 35281-9.

Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner., Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC., J Pharmacol Exp Ther. September 1, 2005; 314 (3): 1353-61.

A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene., Golbang AP, Murthy M, Hamad A, Liu CH, Cope G, Van't Hoff W, Cuthbert A, O'Shaughnessy KM., Hypertension. August 1, 2005; 46 (2): 295-300.

Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK)., O'Connell AD, Leng Q, Dong K, MacGregor GG, Giebisch G, Hebert SC., Proc Natl Acad Sci U S A. July 12, 2005; 102 (28): 9954-9.

Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice., Yamauchi K, Yang SS, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S., Biochem Biophys Res Commun. July 8, 2005; 332 (3): 750-5.

Subunit stoichiometry of the Kir1.1 channel in proton-dependent gating., Wang R, Su J, Wang X, Piao H, Zhang X, Adams CY, Cui N, Jiang C., J Biol Chem. April 8, 2005; 280 (14): 13433-41.

Structural locus of the pH gate in the Kir1.1 inward rectifier channel., Sackin H, Nanazashvili M, Palmer LG, Krambis M, Walters DE., Biophys J. April 1, 2005; 88 (4): 2597-606.

ROMK1 channel activity is regulated by monoubiquitination., Lin DH, Sterling H, Wang Z, Babilonia E, Yang B, Dong K, Hebert SC, Giebisch G, Wang WH., Proc Natl Acad Sci U S A. March 22, 2005; 102 (12): 4306-11.

Basolateral K+ conductance in principal cells of rat CCD., Gray DA, Frindt G, Zhang YY, Palmer LG., Am J Physiol Renal Physiol. March 1, 2005; 288 (3): F493-504.

Inhibition of ROMK potassium channel by syntaxin 1A., Sun TJ, Zeng WZ, Huang CL., Am J Physiol Renal Physiol. February 1, 2005; 288 (2): F284-9.

[WNK1 and WNK4, new players in salt and water homeostasis], Hadchouel J, Delaloy C, Jeunemaitre X., Med Sci (Paris). January 1, 2005; 21 (1): 55-60.

Carboxy-terminal determinants of conductance in inward-rectifier K channels., Zhang YY, Robertson JL, Gray DA, Palmer LG., J Gen Physiol. December 1, 2004; 124 (6): 729-39.                      

Regulation of Kir channels by intracellular pH and extracellular K(+): mechanisms of coupling., Dahlmann A, Li M, Gao Z, McGarrigle D, Sackin H, Palmer LG., J Gen Physiol. April 1, 2004; 123 (4): 441-54.                          

Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels., Sackin H, Palmer LG, Krambis M., Biophys J. April 1, 2004; 86 (4): 2145-55.

Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins., Yamauchi K, Rai T, Kobayashi K, Sohara E, Suzuki T, Itoh T, Suda S, Hayama A, Sasaki S, Uchida S., Proc Natl Acad Sci U S A. March 30, 2004; 101 (13): 4690-4.

Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions., Yoo D, Flagg TP, Olsen O, Raghuram V, Foskett JK, Welling PA., J Biol Chem. February 20, 2004; 279 (8): 6863-73.

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia., Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP., Proc Natl Acad Sci U S A. February 17, 2004; 101 (7): 2064-9.

Expression and coexpression of CO2-sensitive Kir channels in brainstem neurons of rats., Wu J, Xu H, Shen W, Jiang C., J Membr Biol. February 1, 2004; 197 (3): 179-91.

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion., Kahle KT, Wilson FH, Leng Q, Lalioti MD, O'Connell AD, Dong K, Rapson AK, MacGregor GG, Giebisch G, Hebert SC, Lifton RP., Nat Genet. December 1, 2003; 35 (4): 372-6.

Dietary potassium restriction stimulates endocytosis of ROMK channel in rat cortical collecting duct., Chu PY, Quigley R, Babich V, Huang CL., Am J Physiol Renal Physiol. December 1, 2003; 285 (6): F1179-87.

Molecular requirements for the regulation of the renal outer medullary K(+) channel ROMK1 by the serum- and glucocorticoid-inducible kinase SGK1., Palmada M, Embark HM, Yun C, Böhmer C, Lang F., Biochem Biophys Res Commun. November 21, 2003; 311 (3): 629-34.

Multiple epithelial Na+ channel domains participate in subunit assembly., Bruns JB, Hu B, Ahn YJ, Sheng S, Hughey RP, Kleyman TR., Am J Physiol Renal Physiol. October 1, 2003; 285 (4): F600-9.

Classification and rescue of ROMK mutations underlying hyperprostaglandin E syndrome/antenatal Bartter syndrome., Peters M, Ermert S, Jeck N, Derst C, Pechmann U, Weber S, Schlingmann KP, Seyberth HW, Waldegger S, Konrad M., Kidney Int. September 1, 2003; 64 (3): 923-32.

Negative charge at the consensus sequence for the serum- and glucocorticoid-inducible kinase, SGK1, determines pH sensitivity of the renal outer medullary K+ channel, ROMK1., Palmada M, Embark HM, Wyatt AW, Böhmer C, Lang F., Biochem Biophys Res Commun. August 8, 2003; 307 (4): 967-72.

Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A., Yoo D, Kim BY, Campo C, Nance L, King A, Maouyo D, Welling PA., J Biol Chem. June 20, 2003; 278 (25): 23066-75.

Protein kinase C inhibits ROMK1 channel activity via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism., Zeng WZ, Li XJ, Hilgemann DW, Huang CL., J Biol Chem. May 9, 2003; 278 (19): 16852-6.

Mechanism of rectification in inward-rectifier K+ channels., Guo D, Ramu Y, Klem AM, Lu Z., J Gen Physiol. April 1, 2003; 121 (4): 261-75.                        

Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels., Konstas AA, Korbmacher C, Tucker SJ., Am J Physiol Cell Physiol. April 1, 2003; 284 (4): C910-7.

Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac)., Kobayashi T, Washiyama K, Ikeda K., Br J Pharmacol. March 1, 2003; 138 (6): 1119-28.

Permeant cations and blockers modulate pH gating of ROMK channels., Sackin H, Vasilyev A, Palmer LG, Krambis M., Biophys J. February 1, 2003; 84 (2 Pt 1): 910-21.

The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1., Yun CC, Palmada M, Embark HM, Fedorenko O, Feng Y, Henke G, Setiawan I, Boehmer C, Weinman EJ, Sandrasagra S, Korbmacher C, Cohen P, Pearce D, Lang F., J Am Soc Nephrol. December 1, 2002; 13 (12): 2823-30.

Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels., Lin D, Sterling H, Lerea KM, Giebisch G, Wang WH., J Biol Chem. November 15, 2002; 277 (46): 44278-84.

Hydrolyzable ATP and PIP(2) modulate the small-conductance K+ channel in apical membranes of rat cortical-collecting duct (CCD)., Lu M, Hebert SC, Giebisch G., J Gen Physiol. November 1, 2002; 120 (5): 603-15.                    

Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation., Flagg TP, Yoo D, Sciortino CM, Tate M, Romero MF, Welling PA., J Physiol. October 15, 2002; 544 (2): 351-62.

Evidence for endocytosis of ROMK potassium channel via clathrin-coated vesicles., Zeng WZ, Babich V, Ortega B, Quigley R, White SJ, Welling PA, Huang CL., Am J Physiol Renal Physiol. October 1, 2002; 283 (4): F630-9.

Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel., Konstas AA, Koch JP, Tucker SJ, Korbmacher C., J Biol Chem. July 12, 2002; 277 (28): 25377-84.

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