Results 1 - 50 of 57 results
Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components. , Hantel F, Liu H , Fechtner L, Neuhaus H , Ding J, Arlt D, Walentek P , Villavicencio-Lorini P, Gerhardt C, Hollemann T , Pfirrmann T ., J Cell Sci. May 1, 2022; 135 (9):
Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development. , Sun J, Yoon J, Lee M, Lee HK , Hwang YS, Daar IO ., Cell Rep. February 1, 2022; 38 (5): 110312.
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. , Getwan M , Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS ., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):
Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae. , Hamilton AM , Balashova OA, Borodinsky LN ., Elife. May 6, 2021; 10
Modeling endoderm development and disease in Xenopus. , Edwards NA , Zorn AM ., Curr Top Dev Biol. January 1, 2021; 145 61-90.
The critical role of dysregulated Hh- FOXM1- TPX2 signaling in human hepatocellular carcinoma cell proliferation. , Wang Y, Wang H, Yan Z, Li G, Hu G, Zhang H , Huang D, Wang Y, Zhang X, Yan Y, Lu Q, Cheng M, Luo S., Cell Commun Signal. July 28, 2020; 18 (1): 116.
Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation. , Nasr T , Mancini P , Rankin SA , Rankin SA , Edwards NA , Agricola ZN, Kenny AP , Kinney JL, Daniels K, Vardanyan J, Han L , Trisno SL, Cha SW , Wells JM , Kofron MJ , Zorn AM ., Dev Cell. December 16, 2019; 51 (6): 665-674.e6.
Xenopus slc7a5 is essential for notochord function and eye development. , Katada T, Sakurai H., Mech Dev. February 1, 2019; 155 48-59.
Gli2 is required for the induction and migration of Xenopus laevis neural crest. , Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ , Aybar MJ ., Mech Dev. December 1, 2018; 154 219-239.
Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear. , Zarei S, Zarei K, Fritzsch B , Elliott KL., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.
An analysis of MyoD-dependent transcription using CRISPR/Cas9 gene targeting in Xenopus tropicalis embryos. , McQueen C, Pownall ME ., Mech Dev. August 1, 2017; 146 1-9.
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. , Michiue T , Yamamoto T , Yasuoka Y, Goto T , Ikeda T, Nagura K, Nakayama T , Taira M , Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.
Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. , Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G , Arnold SJ, Lienkamp SS ., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.
Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. , Jin Z, Schwend T , Fu J, Bao Z, Liang J, Zhao H , Mei W, Yang J ., Development. November 1, 2016; 143 (21): 3944-3955.
A Retinoic Acid- Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. , Rankin SA , Rankin SA , Han L , McCracken KW, Kenny AP , Anglin CT, Grigg EA, Crawford CM, Wells JM , Shannon JM, Zorn AM ., Cell Rep. June 28, 2016; 16 (1): 66-78.
Noggin-Mediated Retinal Induction Reveals a Novel Interplay Between Bone Morphogenetic Protein Inhibition, Transforming Growth Factor β, and Sonic Hedgehog Signaling. , Messina A, Lan L, Incitti T, Bozza A, Andreazzoli M , Vignali R , Cremisi F , Bozzi Y, Casarosa S., Stem Cells. August 1, 2015; 33 (8): 2496-508.
Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. , Belgacem YH, Borodinsky LN ., Proc Natl Acad Sci U S A. March 31, 2015; 112 (13): 4140-5.
Prepatterning and patterning of the thalamus along embryonic development of Xenopus laevis. , Bandín S, Morona R, González A ., Front Neuroanat. February 3, 2015; 9 107.
Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression. , Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW ., Dev Biol. November 15, 2014; 395 (2): 287-98.
Gene regulatory networks governing lung specification. , Rankin SA , Rankin SA , Zorn AM ., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.
Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. , Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R., Cell Rep. January 16, 2014; 6 (1): 168-81.
Stabilization of speckle-type POZ protein ( Spop) by Daz interacting protein 1 ( Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling. , Schwend T , Jin Z, Jiang K, Mitchell BJ , Jia J, Yang J ., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.
The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with the transcription factor Gli1. , Martynova NY, Ermolina LV, Ermakova GV, Eroshkin FM, Gyoeva FK, Baturina NS, Zaraisky AG ., Dev Biol. August 1, 2013; 380 (1): 37-48.
Indian hedgehog signaling is required for proper formation, maintenance and migration of Xenopus neural crest. , Agüero TH, Fernández JP, López GA, Tríbulo C, Aybar MJ ., Dev Biol. April 15, 2012; 364 (2): 99-113.
Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis. , Hasebe T , Kajita M, Fu L, Shi YB , Ishizuya-Oka A ., Dev Dyn. February 1, 2012; 241 (2): 403-14.
The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1. , Jin Z, Mei W, Strack S, Jia J, Yang J ., J Biol Chem. October 21, 2011; 286 (42): 36171-9.
Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. , He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.
Cooperative requirement of the Gli proteins in neurogenesis. , Nguyen V, Chokas AL, Stecca B, Ruiz i Altaba A ., Development. July 1, 2005; 132 (14): 3267-79.
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features. , Roessler E, Du YZ, Mullor JL, Casas E, Allen WP, Gillessen-Kaesbach G, Roeder ER, Ming JE, Ruiz i Altaba A , Muenke M., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13424-9.
The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. , Meyer NP, Roelink H., Dev Biol. May 15, 2003; 257 (2): 343-55.
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. , Perron M , Boy S, Amato MA, Viczian A , Koebernick K, Pieler T , Harris WA ., Development. April 1, 2003; 130 (8): 1565-77.
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. , Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF., Development. April 1, 2003; 130 (8): 1549-64.
Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis. , Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC ., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.
Dorsal- ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. , Persson M, Stamataki D, te Welscher P, Andersson E, Böse J, Rüther U, Ericson J, Briscoe J., Genes Dev. November 15, 2002; 16 (22): 2865-78.
Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development. , Takabatake Y, Takabatake T, Sasagawa S, Takeshima K ., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.
Gli1 can rescue the in vivo function of Gli2. , Bai CB, Joyner AL., Development. December 1, 2001; 128 (24): 5161-72.
Anorectal malformations caused by defects in sonic hedgehog signaling. , Mo R, Kim JH , Zhang J, Chiang C, Hui CC, Kim PC., Am J Pathol. August 1, 2001; 159 (2): 765-74.
Expression pattern of Irx1 and Irx2 during mouse digit development. , Zülch A, Becker MB, Gruss P ., Mech Dev. August 1, 2001; 106 (1-2): 159-62.
Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS. , Brewster R , Ruiz i Altaba A ., Mech Dev. December 1, 2000; 99 (1-2): 159-62.
Similar expression and regulation of Gli2 and Gli3 in the chick limb bud. , Schweitzer R, Vogan KJ, Tabin CJ., Mech Dev. November 1, 2000; 98 (1-2): 171-4.
Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development. , Takabatake T, Takahashi TC, Takabatake Y, Yamada K, Ogawa M, Takeshima K ., Mech Dev. November 1, 2000; 98 (1-2): 99-104.
Gli2 functions in FGF signaling during antero- posterior patterning. , Brewster R , Mullor JL, Ruiz i Altaba A ., Development. October 1, 2000; 127 (20): 4395-405.
Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. , Borycki A, Brown AM, Emerson CP., Development. May 1, 2000; 127 (10): 2075-87.
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. , Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL., Development. April 1, 2000; 127 (8): 1593-605.
Distinct and regulated activities of human Gli proteins in Drosophila. , von Mering C, Basler K., Curr Biol. November 18, 1999; 9 (22): 1319-22.
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. , Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H., Development. September 1, 1999; 126 (17): 3915-24.
Gli proteins encode context-dependent positive and negative functions: implications for development and disease. , Ruiz i Altaba A ., Development. June 1, 1999; 126 (14): 3205-16.
Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. , Motoyama J, Liu J , Mo R, Ding Q, Post M, Hui CC., Nat Genet. September 1, 1998; 20 (1): 54-7.
The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. , Hardcastle Z, Mo R, Hui CC, Sharpe PT., Development. August 1, 1998; 125 (15): 2803-11.
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. , Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC., Development. July 1, 1998; 125 (14): 2533-43.