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Summary Expression Phenotypes Gene Literature (24) GO Terms (17) Nucleotides (152) Proteins (50) Interactants (264) Wiki
XB-GENEPAGE-480617

Papers associated with irx2



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Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate., Gómez-Skarmeta JL, Glavic A, de la Calle-Mustienes E, Modolell J, Mayor R., EMBO J. January 2, 1998; 17 (1): 181-90.

Neuralization of the Xenopus embryo by inhibition of p300/ CREB-binding protein function., Kato Y, Shi Y, Shi Y, He X., J Neurosci. November 1, 1999; 19 (21): 9364-73.          

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand., Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE., Dev Biol. January 15, 2000; 217 (2): 266-77.  

Expression of two novel mouse Iroquois homeobox genes during neurogenesis., Cohen DR, Cheng CW, Cheng SH, Hui CC., Mech Dev. March 1, 2000; 91 (1-2): 317-21.

The Iroquois family of genes: from body building to neural patterning., Cavodeassi F, Modolell J, Gómez-Skarmeta JL., Development. August 1, 2001; 128 (15): 2847-55.      

Expression pattern of Irx1 and Irx2 during mouse digit development., Zülch A, Becker MB, Gruss P., Mech Dev. August 1, 2001; 106 (1-2): 159-62.

Irx1 and Irx2 expression in early lung development., Becker MB, Zülch A, Bosse A, Gruss P., Mech Dev. August 1, 2001; 106 (1-2): 155-8.

Neural induction takes a transcriptional twist., Bainter JJ, Boos A, Kroll KL., Dev Dyn. November 1, 2001; 222 (3): 315-27.  

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice., Lebel M, Agarwal P, Cheng CW, Kabir MG, Chan TY, Thanabalasingham V, Zhang X, Cohen DR, Husain M, Cheng SH, Bruneau BG, Hui CC., Mol Cell Biol. November 1, 2003; 23 (22): 8216-25.

The prepattern transcription factor Irx3 directs nephron segment identity., Reggiani L, Raciti D, Airik R, Kispert A, Brändli AW., Genes Dev. September 15, 2007; 21 (18): 2358-70.                

A dual requirement for Iroquois genes during Xenopus kidney development., Alarcón P, Rodríguez-Seguel E, Fernández-González A, Rubio R, Gómez-Skarmeta JL., Development. October 1, 2008; 135 (19): 3197-207.                            

foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation., Yan B, Neilson KM, Moody SA., Dev Biol. May 1, 2009; 329 (1): 80-95.              

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation., Tena JJ, Alonso ME, de la Calle-Mustienes E, Splinter E, de Laat W, Manzanares M, Gómez-Skarmeta JL., Nat Commun. January 1, 2011; 2 310.    

Gsx transcription factors repress Iroquois gene expression., Winterbottom EF, Ramsbottom SA, Isaacs HV., Dev Dyn. June 1, 2011; 240 (6): 1422-9.        

Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate., Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA., Dev Biol. May 15, 2012; 365 (2): 363-75.                        

HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2., Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyryläinen R, Shan J, Vainio S, Umbhauer M, Cereghini S., Development. February 1, 2013; 140 (4): 873-85.  

Glimpse into Hox and tale regulation of cell differentiation and reprogramming., Cerdá-Esteban N, Spagnoli FM., Dev Dyn. January 1, 2014; 243 (1): 76-87.  

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers., Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH., Dev Biol. February 15, 2014; 386 (2): 461-72.                                            

The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.                    

An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center., Sena E, Feistel K, Durand BC., J Dev Biol. October 20, 2016; 4 (4):       

Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis., Whitworth GB, Misaghi BC, Rosenthal DM, Mills EA, Heinen DJ, Watson AH, Ives CW, Ali SH, Bezold K, Marsh-Armstrong N, Watson FL., Dev Biol. June 15, 2017; 426 (2): 360-373.              

A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo., Blitz IL, Paraiso KD, Patrushev I, Chiu WTY, Cho KWY, Gilchrist MJ., Dev Biol. June 15, 2017; 426 (2): 409-417.        

Hnf1b renal expression directed by a distal enhancer responsive to Pax8., Goea L, Buisson I, Bello V, Eschstruth A, Paces-Fessy M, Le Bouffant R, Chesneau A, Cereghini S, Riou JF, Umbhauer M., Sci Rep. November 19, 2022; 12 (1): 19921.            

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