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Summary Expression Phenotypes Gene Literature (68) GO Terms (7) Nucleotides (111) Proteins (68) Interactants (216) Wiki
XB-GENEPAGE-6037406

Papers associated with scn5a



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Cardiac channelopathy causing sudden death as revealed by molecular autopsy., Kauferstein S, Kiehne N, Peigneur S, Tytgat J, Bratzke H., Int J Legal Med. January 1, 2013; 127 (1): 145-51.


Characterization of N-terminally mutated cardiac Na(+) channels associated with long QT syndrome 3 and Brugada syndrome., Gütter C, Benndorf K, Zimmer T., Front Physiol. June 26, 2013; 4 153.            


Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel., Jones DK, Claydon TW, Ruben PC., Biophys J. July 2, 2013; 105 (1): 101-7.


Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels., Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP., Biochemistry. October 22, 2013; 52 (42): 7439-48.


Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels., Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD., Biochem Pharmacol. May 15, 2014; 89 (2): 276-86.


Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder., Friedrich C, Rinné S, Zumhagen S, Kiper AK, Silbernagel N, Netter MF, Stallmeyer B, Schulze-Bahr E, Decher N., EMBO Mol Med. July 1, 2014; 6 (7): 937-51.              


Voltage-dependent blockade by bupivacaine of cardiac sodium channels expressed in Xenopus oocytes., Zhang H, Ji H, Liu Z, Ji Y, You X, Ding G, Cheng Z., Neurosci Bull. August 1, 2014; 30 (4): 697-710.


Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels., Cristofori-Armstrong B, Soh MS, Talwar S, Brown DL, Griffin JD, Dekan Z, Stow JL, King GF, Lynch JW, Rash LD., Sci Rep. January 12, 2015; 5 14763.                                


The alternative splicing regulator Tra2b is required for somitogenesis and regulates splicing of an inhibitory Wnt11b isoform., Dichmann DS, Walentek P, Harland RM., Cell Rep. February 3, 2015; 10 (4): 527-36.                    


A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms., Peigneur S, Cologna CT, Cremonez CM, Mille BG, Pucca MB, Cuypers E, Arantes EC, Tytgat J., Neuropharmacology. August 1, 2015; 95 269-77.


Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy., Freyermuth F, Rau F, Kokunai Y, Linke T, Sellier C, Nakamori M, Kino Y, Arandel L, Jollet A, Thibault C, Philipps M, Vicaire S, Jost B, Udd B, Day JW, Duboc D, Wahbi K, Matsumura T, Fujimura H, Mochizuki H, Deryckere F, Kimura T, Nukina N, Ishiura S, Lacroix V, Campan-Fournier A, Navratil V, Chautard E, Auboeuf D, Horie M, Imoto K, Lee KY, Swanson MS, de Munain AL, Inada S, Itoh H, Nakazawa K, Ashihara T, Wang E, Zimmer T, Furling D, Takahashi MP, Charlet-Berguerand N., Nat Commun. April 11, 2016; 7 11067.              


Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: identification of novel LQTS3 and BrS mutations., Ortiz-Bonnin B, Rinné S, Moss R, Streit AK, Scharf M, Richter K, Stöber A, Pfeufer A, Seemann G, Kääb S, Beckmann BM, Decher N., Pflugers Arch. August 1, 2016; 468 (8): 1375-87.


Genomic Takeover by Transposable Elements in the Strawberry Poison Frog., Rogers RL, Zhou L, Chu C, Márquez R, Corl A, Linderoth T, Freeborn L, MacManes MD, Xiong Z, Zheng J, Guo C, Xun X, Kronforst MR, Summers K, Wu Y, Yang H, Richards-Zawacki CL, Zhang G, Nielsen R., Mol Biol Evol. December 1, 2018; 35 (12): 2913-2927.              


Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation., Zhu W, Mazzanti A, Voelker TL, Hou P, Moreno JD, Angsutararux P, Naegle KM, Priori SG, Silva JR., Circ Res. February 15, 2019; 124 (4): 539-552.


Distinct functional properties of two electrogenic isoforms of the SLC34 Na-Pi cotransporter., Mizutani N, Okochi Y, Okamura Y., Physiol Rep. July 1, 2019; 7 (14): e14156.              


Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease., Sedaghat-Hamedani F, Rebs S, El-Battrawy I, Chasan S, Krause T, Haas J, Zhong R, Liao Z, Xu Q, Zhou X, Akin I, Zitron E, Frey N, Streckfuss-Bömeke K, Kayvanpour E., Int J Mol Sci. November 30, 2021; 22 (23):             


Metamorphic gene regulation programs in Xenopus tropicalis tadpole brain., Raj S, Sifuentes CJ, Kyono Y, Denver RJ., PLoS One. January 1, 2023; 18 (6): e0287858.                

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