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Summary Expression Phenotypes Gene Literature (28) GO Terms (1) Nucleotides (481) Proteins (162) Interactants (386) Wiki
XB-GENEPAGE-486121

Papers associated with btrc



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Identification of new localized RNAs in the Xenopus oocyte by differential display PCR., Hudson JW, Alarcón VB, Elinson RP., Dev Genet. January 1, 1996; 19 (3): 190-8.                

beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos., Marikawa Y, Elinson RP., Mech Dev. September 1, 1998; 77 (1): 75-80.    

Negative regulation of axis formation and Wnt signaling in Xenopus embryos by the F-box/WD40 protein beta TrCP., Lagna G, Carnevali F, Marchioni M, Hemmati-Brivanlou A., Mech Dev. January 1, 1999; 80 (1): 101-6.        

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin., Latres E, Chiaur DS, Pagano M., Oncogene. January 28, 1999; 18 (4): 849-54.

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1., Hatakeyama S, Kitagawa M, Nakayama K, Shirane M, Matsumoto M, Hattori K, Higashi H, Nakano H, Okumura K, Onoé K, Good RA, Nakayama K., Proc Natl Acad Sci U S A. March 30, 1999; 96 (7): 3859-63.

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation., Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X., Proc Natl Acad Sci U S A. May 25, 1999; 96 (11): 6273-8.            

Keeping a close eye on Wnt-1/wg signaling in Xenopus., Gradl D, Kühl M, Wedlich D., Mech Dev. August 1, 1999; 86 (1-2): 3-15.    

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1., Shirane M, Hatakeyama S, Hattori K, Nakayama K, Nakayama K., J Biol Chem. October 1, 1999; 274 (40): 28169-74.

Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha., Hattori K, Hatakeyama S, Shirane M, Matsumoto M, Nakayama K., J Biol Chem. October 15, 1999; 274 (42): 29641-7.

Expression profiles of betaTRCP1 and betaTRCP2, and mutation analysis of betaTRCP2 in gastric cancer., Saitoh T, Katoh M., Int J Oncol. May 1, 2001; 18 (5): 959-64.

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase., Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK., Dev Cell. June 1, 2003; 4 (6): 813-26.

Identification of positive and negative regulatory regions controlling expression of the Xenopus laevis betaTrCP gene., Ballarino M, Fruscalzo A, Marchioni M, Carnevali F., Gene. July 21, 2004; 336 (2): 275-85.

Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1., Hansen DV, Loktev AV, Ban KH, Jackson PK., Mol Biol Cell. December 1, 2004; 15 (12): 5623-34.

Wnt-dependent regulation of the E-cadherin repressor snail., Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ., J Biol Chem. March 25, 2005; 280 (12): 11740-8.

Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases., Kanemori Y, Uto K, Sagata N., Proc Natl Acad Sci U S A. May 3, 2005; 102 (18): 6279-84.

The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1., Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JD, Jackson PK., Cell. January 27, 2006; 124 (2): 367-80.

Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation., Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR., Nat Cell Biol. October 1, 2006; 8 (10): 1084-94.

Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(betatrcp)., Bernis C, Vigneron S, Burgess A, Labbé JC, Fesquet D, Castro A, Lorca T., EMBO Rep. January 1, 2007; 8 (1): 91-8.

Nuclear localization signals of the E-cadherin transcriptional repressor Snail., Ko H, Kim HS, Kim NH, Lee SH, Kim KH, Hong SH, Yook JI., Cells Tissues Organs. January 1, 2007; 185 (1-3): 66-72.

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.        

Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signaling., Seo E, Kim H, Kim R, Yun S, Kim M, Han JK, Costantini F, Jho EH., Cell Signal. January 1, 2009; 21 (1): 43-51.

The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF beta-TrCP-dependent degradation for cell cycle arrest., Isoda M, Kanemori Y, Nakajo N, Uchida S, Yamashita K, Ueno H, Sagata N., Mol Biol Cell. April 1, 2009; 20 (8): 2186-95.              

Xtr, a plural tudor domain-containing protein, coexists with FRGY2 both in cytoplasmic mRNP particle and germ plasm in Xenopus embryo: its possible role in translational regulation of maternal mRNAs., Golam Mostafa M, Sugimoto T, Hiyoshi M, Kawasaki H, Kubo H, Matsumoto K, Abe S, Takamune K., Dev Growth Differ. August 1, 2009; 51 (6): 595-605.          

Identification of germ plasm-associated transcripts by microarray analysis of Xenopus vegetal cortex RNA., Cuykendall TN, Houston DW., Dev Dyn. June 1, 2010; 239 (6): 1838-48.                              

Genome-Wide Identification and Expression of Xenopus F-Box Family of Proteins., Saritas-Yildirim B, Pliner HA, Ochoa A, Silva EM., PLoS One. September 1, 2015; 10 (9): e0136929.                                                        

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ, Xie SX, Chen YT, Xue JL, Zhang CJ, Zhu F., World J Gastroenterol. September 7, 2016; 22 (33): 7486-99.      

Claspin - checkpoint adaptor and DNA replication factor., Smits VAJ, Cabrera E, Freire R, Gillespie DA., FEBS J. February 1, 2019; 286 (3): 441-455.

Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1., Colding-Christensen CS, Kakulidis ES, Arroyo-Gomez J, Hendriks IA, Arkinson C, Fábián Z, Gambus A, Mailand N, Duxin JP, Nielsen ML., Nat Commun. December 14, 2023; 14 (1): 8293.        

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