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Summary Expression Phenotypes Gene Literature (105) GO Terms (5) Nucleotides (93) Proteins (35) Interactants (862) Wiki
XB-GENEPAGE-6258962

Papers associated with lefty



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A mathematical modelling portrait of Wnt signalling in early vertebrate embryogenesis., Giuraniuc CV, Zain S, Ghafoor S, Hoppler S., J Theor Biol. November 7, 2022; 551-552 111239.                      

Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK., Nat Commun. November 5, 2022; 13 (1): 6681.                                            

HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q., Cell Rep. July 12, 2022; 40 (2): 111038.                              

Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates., Szenker-Ravi E, Ott T, Khatoo M, Moreau de Bellaing A, Goh WX, Chong YL, Beckers A, Kannesan D, Louvel G, Anujan P, Ravi V, Bonnard C, Moutton S, Schoen P, Fradin M, Colin E, Megarbane A, Daou L, Chehab G, Di Filippo S, Rooryck C, Deleuze JF, Boland A, Arribard N, Eker R, Tohari S, Ng AY, Rio M, Lim CT, Eisenhaber B, Eisenhaber F, Venkatesh B, Amiel J, Crollius HR, Gordon CT, Gossler A, Roy S, Attie-Bitach T, Blum M, Bouvagnet P, Reversade B., Nat Genet. January 1, 2022; 54 (1): 62-72.

Pinhead antagonizes Admp to promote notochord formation., Itoh K, Ossipova O, Sokol SY., iScience. May 7, 2021; 24 (6): 102520.                            

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H, Lee YS, Kim SM, Jang S, Choi H, Lee JW, Kim TD, Kim VN., Dev Cell. April 19, 2021; 56 (8): 1118-1130.e6.                                  

Chromatin accessibility and histone acetylation in the regulation of competence in early development., Esmaeili M, Blythe SA, Tobias JW, Zhang K, Yang J, Klein PS., Dev Biol. June 1, 2020; 462 (1): 20-35.                

The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin., Yamazaki S, Gerhold C, Yamamoto K, Ueno Y, Grosse R, Miyamoto K, Harata M., Cells. March 19, 2020; 9 (3):           

Skeletal muscle differentiation drives a dramatic downregulation of RNA polymerase III activity and differential expression of Polr3g isoforms., McQueen C, Hughes GL, Pownall ME., Dev Biol. October 1, 2019; 454 (1): 74-84.                        

Mechanical strain, novel genes and evolutionary insights: news from the frog left-right organizer., Blum M, Ott T., Curr Opin Genet Dev. June 1, 2019; 56 8-14.      

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus., Vick P, Kreis J, Schneider I, Tingler M, Getwan M, Thumberger T, Beyer T, Schweickert A, Blum M., iScience. April 27, 2018; 2 76-85.                                        

A Conserved Role of the Unconventional Myosin 1d in Laterality Determination., Tingler M, Kurz S, Maerker M, Ott T, Fuhl F, Schweickert A, LeBlanc-Straceski JM, Noselli S, Blum M., Curr Biol. March 5, 2018; 28 (5): 810-816.e3.                

Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish., Bisgrove BW, Su YC, Yost HJ., Elife. November 15, 2017; 6                 

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty asymmetric gene expression-independent manner., Pai VP, Willocq V, Pitcairn EJ, Lemire JM, Paré JF, Shi NQ, McLaughlin KA, Levin M., Biol Open. October 15, 2017; 6 (10): 1445-1457.                              

Xenopus pitx3 target genes lhx1 and xnr5 are identified using a novel three-fluor flow cytometry-based analysis of promoter activation and repression., Hooker LN, Smoczer C, Abbott S, Fakhereddin M, Hudson JW, Crawford MJ., Dev Dyn. September 1, 2017; 246 (9): 657-669.                    

Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.                

XenMine: A genomic interaction tool for the Xenopus community., Reid CD, Karra K, Chang J, Piskol R, Li Q, Li JB, Cherry JM, Baker JC., Dev Biol. June 15, 2017; 426 (2): 155-164.          

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis., Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X., Nat Commun. June 7, 2017; 8 15279.              

Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.                            

Leftward Flow Determines Laterality in Conjoined Twins., Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M., Curr Biol. February 20, 2017; 27 (4): 543-548.                

Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development., Tadjuidje E, Kofron M, Mir A, Wylie C, Heasman J, Cha SW., Open Biol. August 1, 2016; 6 (8):             

Conserved roles for cytoskeletal components in determining laterality., McDowell GS, Lemire JM, Paré JF, Cammarata G, Lowery LA, Levin M., Integr Biol (Camb). March 14, 2016; 8 (3): 267-86.

The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry., Endicott SJ, Basu B, Khokha M, Brueckner M., Development. December 1, 2015; 142 (23): 4068-79.                                  

Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes., Tuazon FB, Mullins MC., Semin Cell Dev Biol. June 1, 2015; 42 118-33.

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.              

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus., Gupta R, Wills A, Ucar D, Baker J., Dev Biol. November 1, 2014; 395 (1): 38-49.            

Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming., Jullien J, Miyamoto K, Pasque V, Allen GE, Bradshaw CR, Garrett NJ, Halley-Stott RP, Kimura H, Ohsumi K, Gurdon JB., Mol Cell. August 21, 2014; 55 (4): 524-36.              

The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid(3) ciliopathy., Stephen LA, Johnson EJ, Davis GM, McTeir L, Pinkham J, Jaberi N, Davey MG., Genesis. June 1, 2014; 52 (6): 600-13.            

The evolution and conservation of left-right patterning mechanisms., Blum M, Feistel K, Thumberger T, Schweickert A., Development. April 1, 2014; 141 (8): 1603-13.              

Wave pinning and spatial patterning in a mathematical model of Antivin/Lefty-Nodal signalling., Middleton AM, King JR, Loose M., J Math Biol. December 1, 2013; 67 (6-7): 1393-424.

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                

Left-right asymmetry: lessons from Cancún., Burdine RD, Caspary T., Development. November 1, 2013; 140 (22): 4465-70.    

It's never too early to get it Right: A conserved role for the cytoskeleton in left-right asymmetry., Vandenberg LN, Lemire JM, Levin M., Commun Integr Biol. November 1, 2013; 6 (6): e27155.          

Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish., Peterson AG, Wang X, Yost HJ., Dev Biol. October 1, 2013; 382 (1): 198-208.    

Developmental mechanisms directing early anterior forebrain specification in vertebrates., Andoniadou CL, Martinez-Barbera JP., Cell Mol Life Sci. October 1, 2013; 70 (20): 3739-52.        

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

Serotonin has early, cilia-independent roles in Xenopus left-right patterning., Vandenberg LN, Lemire JM, Levin M., Dis Model Mech. January 1, 2013; 6 (1): 261-8.    

Self-regulation of the head-inducing properties of the Spemann organizer., Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S., Proc Natl Acad Sci U S A. September 18, 2012; 109 (38): 15354-9.                            

RFX2 is broadly required for ciliogenesis during vertebrate development., Chung MI, Peyrot SM, LeBoeuf S, Park TJ, McGary KL, Marcotte EM, Wallingford JB., Dev Biol. March 1, 2012; 363 (1): 155-65.                                                          

BMP inhibition by DAN in Hensen's node is a critical step for the establishment of left-right asymmetry in the chick embryo., Katsu K, Tokumori D, Tatsumi N, Suzuki A, Yokouchi Y., Dev Biol. March 1, 2012; 363 (1): 15-26.

Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach., Schweickert A, Walentek P, Thumberger T, Danilchik M., Differentiation. February 1, 2012; 83 (2): S67-77.      

Laterality defects are influenced by timing of treatments and animal model., Vandenberg LN., Differentiation. January 1, 2012; 83 (1): 26-37.          

Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry., Pai VP, Vandenberg LN, Blackiston D, Levin M., Stem Cells Int. January 1, 2012; 2012 353491.          

HEB and E2A function as SMAD/FOXH1 cofactors., Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC., Genes Dev. August 1, 2011; 25 (15): 1654-61.            

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