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The Multifaceted Roles of USP15 in Signal Transduction. , Das T, Song EJ, Kim EE ., Int J Mol Sci. April 29, 2021; 22 (9):
Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. , Magnussen HM, Huang DT., J Mol Biol. March 5, 2021; 433 (5): 166807.
Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma. , Feng C, Zhang HL , Zeng A, Bai M, Wang XJ ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.
Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model. , Tran DP, Kitao A., J Phys Chem B. March 21, 2019; 123 (11): 2469-2478.
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer. , Chen M, Zhang H , Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.
Photoactivation of MDM2 Inhibitors: Controlling Protein-Protein Interaction with Light. , Hansen MJ, Feringa FM, Kobauri P, Szymanski W, Medema RH, Feringa BL., J Am Chem Soc. October 17, 2018; 140 (41): 13136-13141.
Initiation and maintenance of pluripotency gene expression in the absence of cohesin. , Lavagnolli T, Gupta P, Hörmanseder E , Mira-Bontenbal H, Dharmalingam G, Carroll T , Gurdon JB , Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.
Comparative studies of apoptosis in Xenopus laevis and mouse thymoma cell lines. , Johnson RO, Tittle TV, Sefchick MP, Zettergren LD , Ruben LN, Clothier RH, Balls M., Altern Lab Anim. July 1, 2013; 41 (3): 211-8.
MicroRNA-9 reveals regional diversity of neural progenitors along the anterior- posterior axis. , Bonev B, Pisco A, Papalopulu N ., Dev Cell. January 18, 2011; 20 (1): 19-32.
Aromatic-aromatic interactions in the formation of the MDM2- p53 complex. , Espinoza-Fonseca LM, García-Machorro J., Biochem Biophys Res Commun. June 13, 2008; 370 (4): 547-51.
Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft. , Showalter SA, Bruschweiler-Li L, Johnson E, Zhang F, Brüschweiler R., J Am Chem Soc. May 21, 2008; 130 (20): 6472-8.
Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer. , Villiard E, Brinkmann H, Moiseeva O, Mallette FA, Ferbeyre G, Roy S., BMC Evol Biol. September 28, 2007; 7 180.
Occurrence of pre-MBT synthesis of caspase-8 mRNA and activation of caspase-8 prior to execution of SAMDC ( S-adenosylmethionine decarboxylase)-induced, but not p53-induced, apoptosis in Xenopus late blastulae. , Shiokawa K, Takayama E, Higo T, Kuroyanagi S, Kaito C, Hara H, Kajitani M, Sekimizu K, Tadakuma T, Miura K, Igarashi K, Yaoita Y ., Biochem Biophys Res Commun. October 21, 2005; 336 (2): 682-91.
Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding. , Uhrinova S, Uhrin D, Powers H, Watt K, Zheleva D, Fischer P, McInnes C, Barlow PN., J Mol Biol. July 15, 2005; 350 (3): 587-98.
NMR structure of a complex between MDM2 and a small molecule inhibitor. , Fry DC, Emerson SD, Palme S, Vu BT, Liu CM, Podlaski F., J Biomol NMR. October 1, 2004; 30 (2): 163-73.
Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis. , Gu L, Zheng H, Murray SA, Ying H, Jim Xiao ZX., Biochem Biophys Res Commun. March 7, 2003; 302 (2): 384-91.
Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis. , Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC ., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.
Monoclonal antibodies raised against Xenopus p53 interact with human p73. , Le Bras M, Delattre V, Bensaad K, Blandino G, Soussi T., Oncogene. February 14, 2002; 21 (8): 1304-8.
QSAR: hydropathic analysis of inhibitors of the p53- mdm2 interaction. , Galatin PS, Abraham DJ., Proteins. November 15, 2001; 45 (3): 169-75.
Critical residues of epitopes recognized by several anti- p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein. , Portefaix JM, Thebault S, Bourgain-Guglielmetti F, Del Rio M, Granier C, Mani JC, Navarro-Teulon I, Nicolas M, Soussi T, Pau B., J Immunol Methods. October 20, 2000; 244 (1-2): 17-28.
The Mdm2 gene of zebrafish (Danio rerio): preferential expression during development of neural and muscular tissues, and absence of tumor formation after overexpression of its cDNA during early embryogenesis. , Thisse C, Neel H, Thisse B, Daujat S, Piette J., Differentiation. October 1, 2000; 66 (2-3): 61-70.
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. , Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM., EMBO J. March 15, 1999; 18 (6): 1660-72.
Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein. , Bessard AC, Garay E, Lacronique V, Legros Y, Demarquay C, Houque A, Portefaix JM, Granier C, Soussi T., Oncogene. February 19, 1998; 16 (7): 883-90.
Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis. , Marechal V, Elenbaas B, Taneyhill L, Piette J, Mechali M , Nicolas JC, Levine AJ, Moreau J ., Oncogene. March 27, 1997; 14 (12): 1427-33.