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Summary Expression Phenotypes Gene Literature (59) GO Terms (21) Nucleotides (112) Proteins (56) Interactants (375) Wiki

Papers associated with pak1

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7 paper(s) referencing morpholinos

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Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula., Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R., Development. March 29, 2021; 148 (18):                                   

PAK1 Regulates MEC-17 Acetyltransferase Activity and Microtubule Acetylation during Proplatelet Extension., van Dijk J, Bompard G, Rabeharivelo G, Cau J, Delsert C, Morin N., Int J Mol Sci. October 13, 2020; 21 (20):

GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM., Cell Rep. July 28, 2020; 32 (4): 107973.                                      

Opposite Modulation of RAC1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders., Barbosa S, Greville-Heygate S, Bonnet M, Godwin A, Fagotto-Kaufmann C, Kajava AV, Laouteouet D, Mawby R, Wai HA, Dingemans AJM, Hehir-Kwa J, Willems M, Capri Y, Mehta SG, Cox H, Goudie D, Vansenne F, Turnpenny P, Vincent M, Cogné B, Lesca G, Hertecant J, Rodriguez D, Keren B, Burglen L, Gérard M, Putoux A, null null, Cantagrel V, Siquier-Pernet K, Rio M, Banka S, Sarkar A, Steeves M, Parker M, Clement E, Moutton S, Tran Mau-Them F, Piton A, de Vries BBA, Guille M, Debant A, Schmidt S, Baralle D., Am J Hum Genet. March 5, 2020; 106 (3): 338-355.                            

In vitro modeling of Batrachochytrium dendrobatidis infection of the amphibian skin., Verbrugghe E, Van Rooij P, Favoreel H, Martel A, Pasmans F., PLoS One. November 14, 2019; 14 (11): e0225224.        

β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells., Ho PY, Li H, Pavlov TS, Tuerk RD, Tabares D, Brunisholz R, Neumann D, Staruschenko A, Hallows KR., J Biol Chem. July 20, 2018; 293 (29): 11612-11624.

PDGF-A suppresses contact inhibition during directional collective cell migration., Nagel M, Winklbauer R., Development. July 5, 2018; 145 (13):                     

Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance., Kerstein PC, Patel KM, Gomez TM., J Neurosci. February 8, 2017; 37 (6): 1568-1580.                

Intracytoplasmic Transport of Hepatitis B Virus Capsids., Osseman Q, Kann M., Methods Mol Biol. January 1, 2017; 1540 37-51.

Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation., Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH., Cell Death Differ. October 1, 2016; 23 (10): 1638-47.

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES., Watson JR, Fox HM, Nietlispach D, Gallop JL, Owen D, Mott HR., J Biol Chem. June 24, 2016; 291 (26): 13875-90.                  

Atypical RhoV and RhoU GTPases control development of the neural crest., Faure S, Fort P., Small GTPases. October 2, 2015; 6 (4): 174-7.

EphA4-dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula., Evren S, Wen JW, Luu O, Damm EW, Nagel M, Winklbauer R., Development. October 1, 2014; 141 (19): 3649-61.                              

Exploiting polypharmacology for drug target deconvolution., Gujral TS, Peshkin L, Kirschner MW., Proc Natl Acad Sci U S A. April 1, 2014; 111 (13): 5048-53.        

Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly., Soto X, Li J, Lea R, Dubaissi E, Papalopulu N, Amaya E., Proc Natl Acad Sci U S A. July 2, 2013; 110 (27): 11029-34.                                      

PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth., Santiago-Medina M, Gregus KA, Gomez TM., J Cell Sci. March 1, 2013; 126 (Pt 5): 1122-33.

Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin., Valls G, Codina M, Miller RK, Del Valle-Pérez B, Vinyoles M, Caelles C, McCrea PD, García de Herreros A, Duñach M., J Cell Sci. November 15, 2012; 125 (Pt 22): 5288-301.                

The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling., Jean S, Tremblay MG, Herdman C, Guillou F, Moss T., Biol Open. August 15, 2012; 1 (8): 731-8.          

The p21-activated kinase Pak1 regulates induction and migration of the neural crest in Xenopus., Bisson N, Wedlich D, Moss T., Cell Cycle. April 1, 2012; 11 (7): 1316-24.

Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus., Park BY, Hong CS, Weaver JR, Rosocha EM, Saint-Jeannet JP., Dev Biol. February 1, 2012; 362 (1): 65-75.                

Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/RhoV., Shepelev MV, Korobko IV., Biochemistry (Mosc). January 1, 2012; 77 (1): 26-32.

Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus., Nie S, Kee Y, Bronner-Fraser M., Mol Biol Cell. September 1, 2011; 22 (18): 3355-65.                                                

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters., Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.              

Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs)., Mortensen RD, Serra M, Steitz JA, Vasudevan S., Proc Natl Acad Sci U S A. May 17, 2011; 108 (20): 8281-6.          

Activity of the RhoU/Wrch1 GTPase is critical for cranial neural crest cell migration., Fort P, Guémar L, Vignal E, Morin N, Notarnicola C, de Santa Barbara P, Faure S., Dev Biol. February 15, 2011; 350 (2): 451-63.                      

Isolation and characterisation of prolactin-releasing peptide in chicks and its effect on prolactin release and feeding behaviour., Tachibana T, Moriyama S, Takahashi A, Tsukada A, Oda A, Takeuchi S, Sakamoto T., J Neuroendocrinol. January 1, 2011; 23 (1): 74-81.

Phosphoinositides are essential coactivators for p21-activated kinase 1., Strochlic TI, Viaud J, Rennefahrt UE, Anastassiadis T, Peterson JR., Mol Cell. November 12, 2010; 40 (3): 493-500.

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis., Bompard G, Rabeharivelo G, Frank M, Cau J, Delsert C, Morin N., J Cell Biol. September 6, 2010; 190 (5): 807-22.                    

Role of p21-activated kinase in cell polarity and directional mesendoderm migration in the Xenopus gastrula., Nagel M, Luu O, Bisson N, Macanovic B, Moss T, Winklbauer R., Dev Dyn. July 1, 2009; 238 (7): 1709-26.  

Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization., Dzamba BJ, Jakab KR, Marsden M, Schwartz MA, DeSimone DW., Dev Cell. March 1, 2009; 16 (3): 421-32.

Rac regulates the interaction of fascin with protein kinase C in cell migration., Parsons M, Adams JC., J Cell Sci. September 1, 2008; 121 (Pt 17): 2805-13.

The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties., Kreis P, Rousseau V, Thévenot E, Combeau G, Barnier JV., J Neurochem. August 1, 2008; 106 (3): 1184-97.

Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1)., Wu CF, Delsert C, Faure S, Traverso EE, Kloc M, Kuang J, Etkin LD, Morin N., Dev Biol. August 1, 2007; 308 (1): 169-86.              

Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development., Luo T, Xu Y, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD., Development. April 1, 2007; 134 (7): 1279-89.      

EphA4 signaling regulates blastomere adhesion in the Xenopus embryo by recruiting Pak1 to suppress Cdc42 function., Bisson N, Poitras L, Mikryukov A, Tremblay M, Moss T., Mol Biol Cell. March 1, 2007; 18 (3): 1030-43.                  

Xenopus p21-activated kinase 5 regulates blastomeres' adhesive properties during convergent extension movements., Faure S, Cau J, de Santa Barbara P, Bigou S, Ge Q, Delsert C, Morin N., Dev Biol. January 15, 2005; 277 (2): 472-92.    

The Xenopus laevis morphogenetic factor, tumorhead, causes defects in polarized growth and cytokinesis in the fission yeast, Schizosaccharomyces pombe., Wu CF, Yang P, Traverso EE, Etkin LD, Marcus S., Biochem Biophys Res Commun. December 10, 2004; 325 (2): 439-44.

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance., Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N., J Cell Biol. November 22, 2004; 167 (4): 687-98.                  

The catalytic domain of xPAK1 is sufficient to induce myosin II dependent in vivo cell fragmentation independently of other apoptotic events., Bisson N, Islam N, Poitras L, Jean S, Bresnick A, Moss T., Dev Biol. November 15, 2003; 263 (2): 264-81.  

PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase., Poitras L, Jean S, Islam N, Moss T., FEBS Lett. May 22, 2003; 543 (1-3): 129-35.

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition., Tran NH, Frost JA., J Biol Chem. March 28, 2003; 278 (13): 11221-6.

XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis., Souopgui J, Sölter M, Pieler T., EMBO J. December 2, 2002; 21 (23): 6429-39.

Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1., Luo ZG, Wang Q, Zhou JZ, Wang J, Luo Z, Liu M, He X, Wynshaw-Boris A, Xiong WC, Lu B, Mei L., Neuron. August 1, 2002; 35 (3): 489-505.

Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis., Banerjee M, Worth D, Prowse DM, Nikolic M., Curr Biol. July 23, 2002; 12 (14): 1233-9.

A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization., Cau J, Faure S, Comps M, Delsert C, Morin N., J Cell Biol. December 10, 2001; 155 (6): 1029-42.                    

ICln is essential for cellular and early embryonic viability., Pu WT, Wickman K, Clapham DE., J Biol Chem. April 28, 2000; 275 (17): 12363-6.

The cytoskeletal effector xPAK1 is expressed during both ear and lateral line development in Xenopus., Islam N, Poitras L, Moss T., Int J Dev Biol. February 1, 2000; 44 (2): 245-8.          

Regulation of Xenopus p21-activated kinase (X-PAK2) by Cdc42 and maturation-promoting factor controls Xenopus oocyte maturation., Cau J, Faure S, Vigneron S, Labbé JC, Delsert C, Morin N., J Biol Chem. January 28, 2000; 275 (4): 2367-75.

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase., Yoshii S, Tanaka M, Otsuki Y, Wang DY, Guo RJ, Zhu Y, Takeda R, Hanai H, Kaneko E, Sugimura H., Oncogene. October 7, 1999; 18 (41): 5680-90.

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