???pagination.result.count???
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. , Lagna G, Hata A, Hemmati-Brivanlou A , Massagué J., Nature. October 31, 1996; 383 (6603): 832-6.
Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway. , Nakao A, Röijer E, Imamura T, Souchelnytskyi S, Stenman G, Heldin CH, ten Dijke P., J Biol Chem. January 31, 1997; 272 (5): 2896-900.
The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function. , Zhang Y , Musci T , Derynck R., Curr Biol. April 1, 1997; 7 (4): 270-6.
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. , Hata A, Lo RS, Wotton D, Lagna G, Massagué J., Nature. July 3, 1997; 388 (6637): 82-7.
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. , Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, Tamaki K, Hanai J, Heldin CH, Miyazono K, ten Dijke P., EMBO J. September 1, 1997; 16 (17): 5353-62.
Smad4 and FAST-1 in the assembly of activin-responsive factor. , Chen X, Weisberg E, Fridmacher V, Watanabe M, Naco G, Whitman M ., Nature. September 4, 1997; 389 (6646): 85-9.
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. , Nakao A, Afrakhte M, Morén A, Nakayama T , Christian JL , Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P., Nature. October 9, 1997; 389 (6651): 631-5.
Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads. , Candia AF , Watabe T, Hawley SH, Onichtchouk D, Zhang Y , Derynck R, Niehrs C , Cho KW ., Development. November 1, 1997; 124 (22): 4467-80.
Dual role of the Smad4/ DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. , Liu F, Pouponnot C, Massagué J., Genes Dev. December 1, 1997; 11 (23): 3157-67.
XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos. , Howell M, Hill CS ., EMBO J. December 15, 1997; 16 (24): 7411-21.
Smad6 inhibits BMP/ Smad1 signaling by specifically competing with the Smad4 tumor suppressor. , Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A ., Genes Dev. January 15, 1998; 12 (2): 186-97.
Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line. , Shimizu A, Kato M, Nakao A, Imamura T, ten Dijke P, Heldin CH, Kawabata M, Shimada S, Miyazono K., Genes Cells. February 1, 1998; 3 (2): 125-34.
Midkine counteracts the activin signal in mesoderm induction and promotes neural formation. , Yokota C, Takahashi S , Eisaki A, Asashima M , Akhter S, Muramatsu T, Kadomatsu K., J Biochem. February 1, 1998; 123 (2): 339-46.
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. , Hsu DR, Economides AN, Wang X , Eimon PM, Harland RM ., Mol Cell. April 1, 1998; 1 (5): 673-83.
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression. , Crease DJ, Dyson S, Gurdon JB ., Proc Natl Acad Sci U S A. April 14, 1998; 95 (8): 4398-403.
Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer. , Casellas R, Brivanlou AH ., Dev Biol. June 1, 1998; 198 (1): 1-12.
Smad2 role in mesoderm formation, left- right patterning and craniofacial development. , Nomura M, Li E., Nature. June 25, 1998; 393 (6687): 786-90.
Characterization of human FAST-1, a TGF beta and activin signal transducer. , Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B., Mol Cell. July 1, 1998; 2 (1): 121-7.
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. , Labbé E, Silvestri C, Hoodless PA, Wrana JL, Attisano L., Mol Cell. July 1, 1998; 2 (1): 109-20.
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. , Weinstein M, Yang X, Li C, Xu X, Gotay J, Deng CX., Proc Natl Acad Sci U S A. August 4, 1998; 95 (16): 9378-83.
Smad7 inhibits mesoderm formation and promotes neural cell fate in Xenopus embryos. , Bhushan A , Chen Y , Vale W., Dev Biol. August 15, 1998; 200 (2): 260-8.
Smad3 mutant mice develop metastatic colorectal cancer. , Zhu Y, Richardson JA, Parada LF, Graff JM ., Cell. September 18, 1998; 94 (6): 703-14.
Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors. , Souchelnytskyi S, Nakayama T , Nakao A, Morén A, Heldin CH, Christian JL , ten Dijke P., J Biol Chem. September 25, 1998; 273 (39): 25364-70.
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. , Macías-Silva M, Hoodless PA, Tang SJ, Buchwald M, Wrana JL., J Biol Chem. October 2, 1998; 273 (40): 25628-36.
A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis. , Weisberg E, Winnier GE, Chen X, Farnsworth CL, Hogan BL , Whitman M ., Mech Dev. December 1, 1998; 79 (1-2): 17-27.
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor. , Tsukazaki T, Chiang TA, Davison AF, Attisano L, Wrana JL., Cell. December 11, 1998; 95 (6): 779-91.
The embryonic expression of the tissue-specific transcription factor HNF1alpha in Xenopus: rapid activation by HNF4 and delayed induction by mesoderm inducers. , Nastos A, Pogge von Strandmann E, Weber H, Ryffel GU ., Nucleic Acids Res. December 15, 1998; 26 (24): 5602-8.
FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals. , Liu B, Dou CL, Prabhu L, Lai E ., Mol Cell Biol. January 1, 1999; 19 (1): 424-30.
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. , Yagi K, Goto D, Hamamoto T, Takenoshita S, Kato M, Miyazono K., J Biol Chem. January 8, 1999; 274 (2): 703-9.
Drosophila dSmad2 and Atr-I transmit activin/ TGFbeta signals. , Das P, Inoue H, Baker JC , Beppu H, Kawabata M, Harland RM , Miyazono K, Padgett RW., Genes Cells. February 1, 1999; 4 (2): 123-34.
A molecular basis for Smad specificity. , Lagna G, Hemmati-Brivanlou A ., Dev Dyn. March 1, 1999; 214 (3): 269-77.
Dominant-negative Smad2 mutants inhibit activin/ Vg1 signaling and disrupt axis formation in Xenopus. , Hoodless PA, Tsukazaki T, Nishimatsu S, Attisano L, Wrana JL, Thomsen GH ., Dev Biol. March 15, 1999; 207 (2): 364-79.
The EGF- CFC protein one-eyed pinhead is essential for nodal signaling. , Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF., Cell. April 2, 1999; 97 (1): 121-32.
Identification of two Smad4 proteins in Xenopus. Their common and distinct properties. , Masuyama N, Hanafusa H , Kusakabe M , Shibuya H , Nishida E ., J Biol Chem. April 23, 1999; 274 (17): 12163-70.
Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals. , Christian JL , Nakayama T ., Bioessays. May 1, 1999; 21 (5): 382-90.
A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation. , Shimizu K, Gurdon JB ., Proc Natl Acad Sci U S A. June 8, 1999; 96 (12): 6791-6.
SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes. , Verschueren K , Remacle JE, Collart C , Kraft H, Baker BS , Tylzanowski P, Nelles L, Wuytens G , Su MT, Bodmer R, Smith JC , Huylebroeck D ., J Biol Chem. July 16, 1999; 274 (29): 20489-98.
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. , Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH ., Nature. August 12, 1999; 400 (6745): 687-93.
The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis. , Yeo CY, Chen X, Whitman M ., J Biol Chem. September 10, 1999; 274 (37): 26584-90.
Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of smad1 and smad5 is required for specific function in the embryo. , Müller F , Blader P, Rastegar S, Fischer N, Knöchel W , Strähle U., Mech Dev. October 1, 1999; 88 (1): 73-88.
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes. , Howell M, Itoh F, Pierreux CE, Valgeirsdottir S, Itoh S, ten Dijke P, Hill CS ., Dev Biol. October 15, 1999; 214 (2): 354-69.
Smad3 inhibits transforming growth factor-beta and activin signaling by competing with Smad4 for FAST-2 binding. , Nagarajan RP, Liu J , Chen Y ., J Biol Chem. October 29, 1999; 274 (44): 31229-35.
FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo. , Watanabe M, Whitman M ., Development. December 1, 1999; 126 (24): 5621-34.
Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4. , Nishinakamura R, Matsumoto Y, Matsuda T, Ariizumi T, Heike T, Asashima M , Yokota T., Dev Biol. December 15, 1999; 216 (2): 481-90.
Left- right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. , Saijoh Y, Adachi H, Sakuma R, Yeo CY, Yashiro K, Watanabe M, Hashiguchi H, Mochida K, Ohishi S, Kawabata M, Miyazono K, Whitman M , Hamada H., Mol Cell. January 1, 2000; 5 (1): 35-47.
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. , Germain S, Howell M, Esslemont GM, Hill CS ., Genes Dev. February 15, 2000; 14 (4): 435-51.
Cloning and characterization of zebrafish smad2, smad3 and smad4. , Dick A, Mayr T, Bauer H, Meier A, Hammerschmidt M., Gene. April 4, 2000; 246 (1-2): 69-80.
Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers. , Yanagisawa K, Uchida K, Nagatake M, Masuda A, Sugiyama M, Saito T, Yamaki K, Takahashi T, Osada H., Oncogene. May 4, 2000; 19 (19): 2305-11.
Activin A signaling directly activates Xenopus winged helix factors XFD-4/4', the orthologues to mammalian MFH-1. , Köster M , Dillinger K , Knöchel W ., Dev Genes Evol. June 1, 2000; 210 (6): 320-4.
Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB. , Nagarajan RP, Chen F, Li W , Vig E, Harrington MA, Nakshatri H, Chen Y ., Biochem J. June 15, 2000; 348 Pt 3 591-6.