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Summary Expression Phenotypes Gene Literature (75) GO Terms (0) Nucleotides (41) Proteins (24) Interactants (145) Wiki
XB-GENEPAGE-855698

Papers associated with slc5a1



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Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter., Turk E, Zabel B, Mundlos S, Dyer J, Wright EM., Nature. March 28, 1991; 350 (6316): 354-6.

Cloning and functional expression of a mammalian Na+/nucleoside cotransporter. A member of the SGLT family., Pajor AM, Wright EM., J Biol Chem. February 25, 1992; 267 (6): 3557-60.

[Thirty years of research on congenital glucose and galactose malabsorption: from phenotype to genotype]., Desjeux JF, Wright EM., Bull Acad Natl Med. January 1, 1993; 177 (1): 125-31; discussion 132-5.

[30 years' work on congenital glucose and galactose malabsorption: from phenotype to genotype]., Desjeux JF, Wright EM., Ann Gastroenterol Hepatol (Paris). October 1, 1993; 29 (5): 263-6; discussion 266-8.

Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter., Veyhl M, Spangenberg J, Püschel B, Poppe R, Dekel C, Fritzsch G, Haase W, Koepsell H., J Biol Chem. November 25, 1993; 268 (33): 25041-53.

The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport., Kanai Y, Stelzner M, Nussberger S, Khawaja S, Hebert SC, Smith CP, Hediger MA., J Biol Chem. August 12, 1994; 269 (32): 20599-606.

Sodium/D-glucose cotransporter charge movements involve polar residues., Panayotova-Heiermann M, Loo DD, Lostao MP, Wright EM., J Biol Chem. August 19, 1994; 269 (33): 21016-20.

Protons drive sugar transport through the Na+/glucose cotransporter (SGLT1)., Hirayama BA, Loo DD, Wright EM., J Biol Chem. August 26, 1994; 269 (34): 21407-10.

SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation., Mackenzie B, Panayotova-Heiermann M, Loo DD, Lever JE, Wright EM., J Biol Chem. September 9, 1994; 269 (36): 22488-91.

Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions., Lostao MP, Hirayama BA, Loo DD, Wright EM., J Membr Biol. November 1, 1994; 142 (2): 161-70.

Kinetics of steady-state currents and charge movements associated with the rat Na+/glucose cotransporter., Panayotova-Heiermann M, Loo DD, Wright EM., J Biol Chem. November 10, 1995; 270 (45): 27099-105.

Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter., Chen XZ, Coady MJ, Jackson F, Berteloot A, Lapointe JY., Biophys J. December 1, 1995; 69 (6): 2405-14.

Arginine-427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane., Lostao MP, Hirayama BA, Panayotova-Heiermann M, Sampogna SL, Bok D, Wright EM., FEBS Lett. December 18, 1995; 377 (2): 181-4.

Membrane topology of the human Na+/glucose cotransporter SGLT1., Turk E, Kerner CJ, Lostao MP, Wright EM., J Biol Chem. January 26, 1996; 271 (4): 1925-34.

Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption., Martín MG, Turk E, Lostao MP, Kerner C, Wright EM., Nat Genet. February 1, 1996; 12 (2): 216-20.

Kinetic separation and characterization of three sugar transport modes in Caco-2 cells., Bissonnette P, Gagné H, Coady MJ, Benabdallah K, Lapointe JY, Berteloot A., Am J Physiol. May 1, 1996; 270 (5 Pt 1): G833-43.

Kinetic and specificity differences between rat, human, and rabbit Na+-glucose cotransporters (SGLT-1)., Hirayama BA, Lostao MP, Panayotova-Heiermann M, Loo DD, Turk E, Wright EM., Am J Physiol. June 1, 1996; 270 (6 Pt 1): G919-26.

Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2., Mackenzie B, Loo DD, Panayotova-Heiermann M, Wright EM., J Biol Chem. December 20, 1996; 271 (51): 32678-83.

Presteady-state currents of the rabbit Na+/glucose cotransporter (SGLT1)., Hazama A, Loo DD, Wright EM., J Membr Biol. January 15, 1997; 155 (2): 175-86.

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid., Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M., J Biol Chem. July 25, 1997; 272 (30): 18982-9.

Five transmembrane helices form the sugar pathway through the Na+/glucose cotransporter., Panayotova-Heiermann M, Eskandari S, Turk E, Zampighi GA, Wright EM., J Biol Chem. August 15, 1997; 272 (33): 20324-7.

Sodium leak pathway and substrate binding order in the Na+-glucose cotransporter., Chen XZ, Coady MJ, Jalal F, Wallendorff B, Lapointe JY., Biophys J. November 1, 1997; 73 (5): 2503-10.

Relationships between Na+/glucose cotransporter (SGLT1) currents and fluxes., Mackenzie B, Loo DD, Wright EM., J Membr Biol. March 15, 1998; 162 (2): 101-6.

Cysteine scanning mutagenesis of the segment between putative transmembrane helices IV and V of the high affinity Na+/Glucose cotransporter SGLT1. Evidence that this region participates in the Na+ and voltage dependence of the transporter., Lo B, Silverman M., J Biol Chem. November 6, 1998; 273 (45): 29341-51.

Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects., Lam JT, Martín MG, Turk E, Hirayama BA, Bosshard NU, Steinmann B, Wright EM., Biochim Biophys Acta. February 24, 1999; 1453 (2): 297-303.

Cloning and functional expression of an SGLT-1-like protein from the Xenopus laevis intestine., Nagata K, Hori N, Sato K, Ohta K, Tanaka H, Hiji Y., Am J Physiol. May 1, 1999; 276 (5): G1251-9.

Purification and functional reconstitution of a truncated human Na(+)/glucose cotransporter (SGLT1) expressed in E. coli., Panayotova-Heiermann M, Leung DW, Hirayama BA, Wright EM., FEBS Lett. October 15, 1999; 459 (3): 386-90.

Voltage and substrate dependence of the inverse transport mode of the rabbit Na(+)/glucose cotransporter (SGLT1)., Sauer GA, Nagel G, Koepsell H, Bamberg E, Hartung K., FEBS Lett. March 3, 2000; 469 (1): 98-100.

Glycoside binding and translocation in Na(+)-dependent glucose cotransporters: comparison of SGLT1 and SGLT3., Díez-Sampedro A, Lostao MP, Wright EM, Hirayama BA., J Membr Biol. July 15, 2000; 176 (2): 111-7.

Expression of the Na+/glucose co-transporter (SGLT1) in the intestine of domestic and wild ruminants., Wood IS, Dyer J, Hofmann RR, Shirazi-Beechey SP., Pflugers Arch. November 1, 2000; 441 (1): 155-62.

Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1., Loo DD, Eskandari S, Boorer KJ, Sarkar HK, Wright EM., J Biol Chem. December 1, 2000; 275 (48): 37414-22.

Isotonic transport by the Na+-glucose cotransporter SGLT1 from humans and rabbit., Zeuthen T, Meinild AK, Loo DD, Wright EM, Klaerke DA., J Physiol. March 15, 2001; 531 (Pt 3): 631-44.

A missense mutation in the Na(+)/glucose cotransporter gene SGLT1 in a patient with congenital glucose-galactose malabsorption: normal trafficking but inactivation of the mutant protein., Kasahara M, Maeda M, Hayashi S, Mori Y, Abe T., Biochim Biophys Acta. May 31, 2001; 1536 (2-3): 141-7.

Mapping the urea channel through the rabbit Na(+)-glucose cotransporter SGLT1., Panayotova-Heiermann M, Wright EM., J Physiol. September 1, 2001; 535 (Pt 2): 419-25.

The plasma membrane-associated protein RS1 decreases transcription of the transporter SGLT1 in confluent LLC-PK1 cells., Korn T, Kühlkamp T, Track C, Schatz I, Baumgarten K, Gorboulev V, Koepsell H., J Biol Chem. November 30, 2001; 276 (48): 45330-40.

Residue 457 controls sugar binding and transport in the Na(+)/glucose cotransporter., Díez-Sampedro A, Wright EM, Hirayama BA., J Biol Chem. December 28, 2001; 276 (52): 49188-94.

Molecular basis for glucose-galactose malabsorption., Wright EM, Turk E, Martin MG., Cell Biochem Biophys. January 1, 2002; 36 (2-3): 115-21.

Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose., Song J, Kwon O, Chen S, Daruwala R, Eck P, Park JB, Levine M., J Biol Chem. May 3, 2002; 277 (18): 15252-60.

Mobility of ions, sugar, and water in the cytoplasm of Xenopus oocytes expressing Na(+)-coupled sugar transporters (SGLT1)., Zeuthen T, Zeuthen E, Klaerke DA., J Physiol. July 1, 2002; 542 (Pt 1): 71-87.

Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes., Blasco T, Aramayona JJ, Alcalde AI, Catalán J, Sarasa M, Sorribas V., Am J Physiol Renal Physiol. October 1, 2003; 285 (4): F799-810.

Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C., Veyhl M, Wagner CA, Gorboulev V, Schmitt BM, Lang F, Koepsell H., J Membr Biol. November 1, 2003; 196 (1): 71-81.

Glucose accumulation can account for the initial water flux triggered by Na+/glucose cotransport., Gagnon MP, Bissonnette P, Deslandes LM, Wallendorff B, Lapointe JY., Biophys J. January 1, 2004; 86 (1 Pt 1): 125-33.

Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB., Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F., Obes Res. May 1, 2004; 12 (5): 862-70.

Transition states of the high-affinity rabbit Na(+)/glucose cotransporter SGLT1 as determined from measurement and analysis of voltage-dependent charge movements., Krofchick D, Huntley SA, Silverman M., Am J Physiol Cell Physiol. July 1, 2004; 287 (1): C46-54.

Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454., Díez-Sampedro A, Loo DD, Wright EM, Zampighi GA, Hirayama BA., Biochemistry. October 19, 2004; 43 (41): 13175-84.

Determination of transport stoichiometry for two cation-coupled myo-inositol cotransporters: SMIT2 and HMIT., Bourgeois F, Coady MJ, Lapointe JY., J Physiol. March 1, 2005; 563 (Pt 2): 333-43.

Membrane topology of loop 13-14 of the Na+/glucose cotransporter (SGLT1): a SCAM and fluorescent labelling study., Gagnon DG, Holt A, Bourgeois F, Wallendorff B, Coady MJ, Lapointe JY., Biochim Biophys Acta. June 30, 2005; 1712 (2): 173-84.

Transport of d-galactose by the gastrointestinal tract of the locust, Locusta migratoria., Pascual I, Berjón A, Lostao MP, Barber A., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2006; 143 (1): 20-6.

Characterization of taurine as inhibitor of sodium glucose transporter., Kim HW, Lee AJ, You S, Park T, Lee DH., Adv Exp Med Biol. January 1, 2006; 583 137-45.

Water transport by Na+-coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution., Zeuthen T, Belhage B, Zeuthen E., J Physiol. February 1, 2006; 570 (Pt 3): 485-99.

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