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Summary Expression Phenotypes Gene Literature (229) GO Terms (4) Nucleotides (67) Proteins (40) Interactants (939) Wiki
XB-GENEPAGE-853107

Papers associated with en2



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Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation., Chang C, Harland RM., Development. November 1, 2007; 134 (21): 3861-72.                

Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6., Guidato S, Itasaki N., Dev Biol. October 15, 2007; 310 (2): 250-63.                

The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo., Hou S, Maccarana M, Min TH, Strate I, Pera EM., Dev Cell. August 1, 2007; 13 (2): 226-41.                      

The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions., Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG., Dev Biol. July 15, 2007; 307 (2): 483-97.        

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

Early molecular effects of ethanol during vertebrate embryogenesis., Yelin R, Kot H, Yelin D, Fainsod A., Differentiation. June 1, 2007; 75 (5): 393-403.                    

The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways., Yan B, Moody SA., Dev Biol. May 1, 2007; 305 (1): 103-19.        

The role of XBtg2 in Xenopus neural development., Sugimoto K, Okabayashi K, Sedohara A, Hayata T, Asashima M., Dev Neurosci. January 1, 2007; 29 (6): 468-79.

Involvement of a Xenopus nuclear GTP-binding protein in optic primordia formation., Tamanoue Y, Hongo I, Okamoto H., Dev Growth Differ. December 1, 2006; 48 (9): 575-85.                    

Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway., Alexandrova EM, Thomsen GH., Dev Biol. November 15, 2006; 299 (2): 398-410.                      

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity., Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.              

Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling., Heeg-Truesdell E, LaBonne C., Dev Biol. October 1, 2006; 298 (1): 71-86.                    

Xenopus Xotx2 and Drosophila otd share similar activities in anterior patterning of the frog embryo., Lunardi A, Vignali R., Dev Genes Evol. September 1, 2006; 216 (9): 511-21.

Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    

Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development., Tadjuidje E, Hollemann T., Dev Dyn. August 1, 2006; 235 (8): 2095-110.                          

Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning., Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK., Dev Dyn. July 1, 2006; 235 (7): 1895-907.                            

Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue., Afelik S, Chen Y, Pieler T., Genes Dev. June 1, 2006; 20 (11): 1441-6.                        

XNF-ATc3 affects neural convergent extension., Borchers A, Fonar Y, Frank D, Baker JC., Development. May 1, 2006; 133 (9): 1745-55.          

FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus., Fletcher RB, Baker JC, Harland RM., Development. May 1, 2006; 133 (9): 1703-14.            

Tes regulates neural crest migration and axial elongation in Xenopus., Dingwell KS, Smith JC., Dev Biol. May 1, 2006; 293 (1): 252-67.                          

Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1., Terada K, Kitayama A, Kanamoto T, Ueno N, Furukawa T., Dev Biol. March 15, 2006; 291 (2): 398-412.          

FGF8, Wnt8 and Myf5 are target genes of Tbx6 during anteroposterior specification in Xenopus embryo., Li HY, Bourdelas A, Carron C, Gomez C, Boucaut JC, Shi DL., Dev Biol. February 15, 2006; 290 (2): 470-81.                    

Regulation of early Xenopus development by ErbB signaling., Nie S, Chang C., Dev Dyn. February 1, 2006; 235 (2): 301-14.                        

The zic1 gene is an activator of Wnt signaling., Merzdorf CS, Sive HL., Int J Dev Biol. January 1, 2006; 50 (7): 611-7.              

Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field., Reversade B, De Robertis EM., Cell. December 16, 2005; 123 (6): 1147-60.                      

The transcription factor Engrailed-2 guides retinal axons., Brunet I, Weinl C, Piper M, Trembleau A, Volovitch M, Harris W, Prochiantz A, Holt C., Nature. November 3, 2005; 438 (7064): 94-8.

Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning., Houston DW, Wylie C., Development. November 1, 2005; 132 (21): 4845-55.              

The Ca2+-induced methyltransferase xPRMT1b controls neural fate in amphibian embryo., Batut J, Vandel L, Leclerc C, Daguzan C, Moreau M, Néant I., Proc Natl Acad Sci U S A. October 18, 2005; 102 (42): 15128-33.                

The assembly of POSH-JNK regulates Xenopus anterior neural development., Kim GH, Park E, Han JK., Dev Biol. October 1, 2005; 286 (1): 256-69.      

Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer., Yamaguti M, Cho KW, Hashimoto C., Dev Dyn. September 1, 2005; 234 (1): 102-13.          

Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels., Yelin R, Schyr RB, Kot H, Zins S, Frumkin A, Pillemer G, Fainsod A., Dev Biol. March 1, 2005; 279 (1): 193-204.                  

Cloning and characterisation of the immunophilin X-CypA in Xenopus laevis., Massé K, Bhamra S, Haldin CE, Jones EA., Gene Expr Patterns. November 1, 2004; 5 (1): 51-60.      

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis., Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W., Dev Cell. October 1, 2004; 7 (4): 525-34.                          

Characterization of two novel N-methyl-D-aspartate antagonists: EAA-090 (2-[8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic acid) and EAB-318 (R-alpha-amino-5-chloro-1-(phosphonomethyl)-1H-benzimidazole-2-propanoic acid hydrochloride)., Sun L, Chiu D, Kowal D, Simon R, Smeyne M, Zukin RS, Olney J, Baudy R, Lin S., J Pharmacol Exp Ther. August 1, 2004; 310 (2): 563-70.

Xenopus XsalF: anterior neuroectodermal specification by attenuating cellular responsiveness to Wnt signaling., Onai T, Sasai N, Matsui M, Sasai Y., Dev Cell. July 1, 2004; 7 (1): 95-106.            

Primitive roles for inhibitory interneurons in developing frog spinal cord., Li WC, Higashijima S, Parry DM, Roberts A, Soffe SR., J Neurosci. June 23, 2004; 24 (25): 5840-8.                

Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus., Kuroda H, Wessely O, De Robertis EM., PLoS Biol. May 1, 2004; 2 (5): E92.                

XIdax, an inhibitor of the canonical Wnt pathway, is required for anterior neural structure formation in Xenopus., Michiue T, Fukui A, Yukita A, Sakurai K, Danno H, Kikuchi A, Asashima M., Dev Dyn. May 1, 2004; 230 (1): 79-90.        

Timed interactions between the Hox expressing non-organiser mesoderm and the Spemann organiser generate positional information during vertebrate gastrulation., Wacker SA, Jansen HJ, McNulty CL, Houtzager E, Durston AJ., Dev Biol. April 1, 2004; 268 (1): 207-19.            

Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways., Moore KB, Mood K, Daar IO, Moody SA., Dev Cell. January 1, 2004; 6 (1): 55-67.                

PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development., Yang J, Wu J, Tan C, Klein PS., Development. December 1, 2003; 130 (23): 5569-78.            

Endogenous Cerberus activity is required for anterior head specification in Xenopus., Silva AC, Filipe M, Kuerner KM, Steinbeisser H, Belo JA., Development. October 1, 2003; 130 (20): 4943-53.              

Integration of multiple signal transducing pathways on Fgf response elements of the Xenopus caudal homologue Xcad3., Haremaki T, Tanaka Y, Hongo I, Yuge M, Okamoto H., Development. October 1, 2003; 130 (20): 4907-17.                  

Wise, a context-dependent activator and inhibitor of Wnt signalling., Itasaki N, Jones CM, Mercurio S, Rowe A, Domingos PM, Smith JC, Krumlauf R., Development. September 1, 2003; 130 (18): 4295-305.                

Yin Yang 1, a vertebrate polycomb group gene, regulates antero-posterior neural patterning., Kwon HJ, Chung HM., Biochem Biophys Res Commun. July 11, 2003; 306 (4): 1008-13.        

Xenopus X-box binding protein 1, a leucine zipper transcription factor, is involved in the BMP signaling pathway., Zhao H, Cao Y, Grunz H., Dev Biol. May 15, 2003; 257 (2): 278-91.          

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.    

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis., Ohkawara B, Yamamoto TS, Tada M, Ueno N., Development. May 1, 2003; 130 (10): 2129-38.                

The germ cell nuclear factor is required for retinoic acid signaling during Xenopus development., Barreto G, Borgmeyer U, Dreyer C., Mech Dev. April 1, 2003; 120 (4): 415-28.            

Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor., Bell E, Muñoz-Sanjuán I, Altmann CR, Vonica A, Brivanlou AH., Development. April 1, 2003; 130 (7): 1381-9.    

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