Papers associated with kcna2

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	An essential role for cortactin in the modulation of the potassium channel Kv1.2., Williams MR, Markey JC, Doczi MA, Morielli AD., Proc Natl Acad Sci U S A. October 30, 2007; 104 (44): 17412-7.
	Tarantula toxins interact with voltage sensors within lipid membranes., Milescu M, Vobecky J, Roh SH, Kim SH, Jung HJ, Kim JI, Swartz KJ., J Gen Physiol. November 1, 2007; 130 (5): 497-511.
	Molecular driving forces determining potassium channel slow inactivation., Cordero-Morales JF, Jogini V, Lewis A, Vásquez V, Cortes DM, Roux B, Perozo E., Nat Struct Mol Biol. November 1, 2007; 14 (11): 1062-9.
	Mg2+ enhances voltage sensor/gate coupling in BK channels., Horrigan FT, Ma Z., J Gen Physiol. January 1, 2008; 131 (1): 13-32.
	Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block., Carvacho I, Gonzalez W, Torres YP, Brauchi S, Alvarez O, Gonzalez-Nilo FD, Latorre R., J Gen Physiol. February 1, 2008; 131 (2): 147-61.
	An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels., Ma Z, Wong KY, Horrigan FT., J Gen Physiol. May 1, 2008; 131 (5): 483-502.
	KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains., Xu X, Jiang M, Hsu KL, Zhang M, Tseng GN., J Gen Physiol. June 1, 2008; 131 (6): 589-603.
	Atomic constraints between the voltage sensor and the pore domain in a voltage-gated K+ channel of known structure., Lewis A, Jogini V, Blachowicz L, Lainé M, Roux B., J Gen Physiol. June 1, 2008; 131 (6): 549-61.
	Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus., Srairi-Abid N, Shahbazzadeh D, Chatti I, Mlayah-Bellalouna S, Mejdoub H, Borchani L, Benkhalifa R, Akbari A, El Ayeb M., FEBS J. September 1, 2008; 275 (18): 4641-50.
	A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes., Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF., Biochem Biophys Res Commun. November 21, 2008; 376 (3): 525-30.
	The molecular basis for the actions of KVbeta1.2 on the opening and closing of the KV1.2 delayed rectifier channel., Peters CJ, Vaid M, Horne AJ, Fedida D, Accili EA., Channels (Austin). January 1, 2009; 3 (5): 314-22.
	Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels., Barghaan J, Bähring R., J Gen Physiol. February 1, 2009; 133 (2): 205-24.
	Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels., Lange W, Geissendörfer J, Schenzer A, Grötzinger J, Seebohm G, Friedrich T, Schwake M., Mol Pharmacol. February 1, 2009; 75 (2): 272-80.
	Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation., Findeisen F, Minor DL., J Gen Physiol. March 1, 2009; 133 (3): 327-43.
	Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels., Lee SY, Banerjee A, MacKinnon R., PLoS Biol. March 3, 2009; 7 (3): e47.
	The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gating., Mazzolini M, Anselmi C, Torre V., J Gen Physiol. April 1, 2009; 133 (4): 375-86.
	Probing S4 and S5 segment proximity in mammalian hyperpolarization-activated HCN channels by disulfide bridging and Cd2+ coordination., Bell DC, Turbendian HK, Valley MT, Zhou L, Riley JH, Siegelbaum SA, Tibbs GR., Pflugers Arch. June 1, 2009; 458 (2): 259-72.
	Divalent cations slow activation of EAG family K+ channels through direct binding to S4., Zhang X, Bursulaya B, Lee CC, Lee CC, Chen B, Pivaroff K, Jegla T., Biophys J. July 8, 2009; 97 (1): 110-20.
	Mutations reveal voltage gating of CNGA1 channels in saturating cGMP., Martínez-François JR, Xu Y, Xu Y, Lu Z., J Gen Physiol. August 1, 2009; 134 (2): 151-64.
	Activation of Slo2.1 channels by niflumic acid., Dai L, Garg V, Sanguinetti MC., J Gen Physiol. March 1, 2010; 135 (3): 275-95.
	Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix., Zhou Y, Tang QY, Xia XM, Lingle CJ., J Gen Physiol. May 1, 2010; 135 (5): 481-94.
	Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening., Lin MC, Abramson J, Papazian DM., J Gen Physiol. May 1, 2010; 135 (5): 415-31.
	Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins., Chen P, Dendorfer A, Finol-Urdaneta RK, Terlau H, Olivera BM., J Biol Chem. May 14, 2010; 285 (20): 14882-14889.
	Fast and slow voltage sensor rearrangements during activation gating in Kv1.2 channels detected using tetramethylrhodamine fluorescence., Horne AJ, Peters CJ, Claydon TW, Fedida D., J Gen Physiol. July 1, 2010; 136 (1): 83-99.
	Induction of vertebrate regeneration by a transient sodium current., Tseng AS, Beane WS, Lemire JM, Masi A, Levin M., J Neurosci. September 29, 2010; 30 (39): 13192-200.
	Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1., Madeja M, Steffen W, Mesic I, Garic B, Zhorov BS., J Biol Chem. October 29, 2010; 285 (44): 33898-905.
	Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anesthetics., Arcisio-Miranda M, Muroi Y, Chowdhury S, Chanda B., J Gen Physiol. November 1, 2010; 136 (5): 541-54.
	Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channel., Pantazis A, Kohanteb AP, Olcese R., J Gen Physiol. December 1, 2010; 136 (6): 645-57.
	A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel., Zarrabi T, Cervenka R, Sandtner W, Lukacs P, Koenig X, Hilber K, Mille M, Lipkind GM, Fozzard HA, Todt H., J Biol Chem. December 10, 2010; 285 (50): 39458-70.
	Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain., Haddad GA, Blunck R., J Gen Physiol. May 1, 2011; 137 (5): 455-72.
	A multipoint hydrogen-bond network underlying KcsA C-type inactivation., Cordero-Morales JF, Jogini V, Chakrapani S, Perozo E., Biophys J. May 18, 2011; 100 (10): 2387-93.
	An electrostatic potassium channel opener targeting the final voltage sensor transition., Börjesson SI, Elinder F., J Gen Physiol. June 1, 2011; 137 (6): 563-77.
	R1 in the Shaker S4 occupies the gating charge transfer center in the resting state., Lin MC, Hsieh JY, Mock AF, Papazian DM., J Gen Physiol. August 1, 2011; 138 (2): 155-63.
	Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway., Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M., J Biol Chem. November 11, 2011; 286 (45): 39091-9.
	Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel., Wu S, Gao W, Xie C, Xu X, Vorvis C, Marni F, Hackett AR, Liu Q, Zhou L., J Gen Physiol. July 1, 2012; 140 (1): 29-39.
	Molecular mechanism for depolarization-induced modulation of Kv channel closure., Labro AJ, Lacroix JJ, Villalba-Galea CA, Snyders DJ, Bezanilla F., J Gen Physiol. November 1, 2012; 140 (5): 481-93.
	Intermediate state trapping of a voltage sensor., Lacroix JJ, Pless SA, Maragliano L, Campos FV, Galpin JD, Ahern CA, Roux B, Bezanilla F., J Gen Physiol. December 1, 2012; 140 (6): 635-52.
	Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Gene. December 10, 2012; 511 (1): 26-33.
	Homology model and targeted mutagenesis identify critical residues for arachidonic acid inhibition of Kv4 channels., Heler R, Bell JK, Boland LM., Channels (Austin). January 1, 2013; 7 (2): 74-84.
	A conserved pre-block interaction motif regulates potassium channel activation and N-type inactivation., Pfaffinger PJ., PLoS One. January 1, 2013; 8 (11): e79891.
	A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel., Pless SA, Niciforovic AP, Galpin JD, Nunez JJ, Kurata HT, Ahern CA., Nat Commun. January 1, 2013; 4 1784.
	Characterization of a ligand binding site in the human transient receptor potential ankyrin 1 pore., Klement G, Eisele L, Malinowsky D, Nolting A, Svensson M, Terp G, Weigelt D, Dabrowski M., Biophys J. February 19, 2013; 104 (4): 798-806.
	Molecular mechanism of voltage sensing in voltage-gated proton channels., Gonzalez C, Rebolledo S, Perez ME, Larsson HP., J Gen Physiol. March 1, 2013; 141 (3): 275-85.
	Fine-tuning of voltage sensitivity of the Kv1.2 potassium channel by interhelix loop dynamics., Sand R, Sharmin N, Morgan C, Gallin WJ., J Biol Chem. April 5, 2013; 288 (14): 9686-9695.
	Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits., Al-Sabi A, Kaza SK, Dolly JO, Wang J., Biochem J. August 15, 2013; 454 (1): 101-8.
	Activation of lysophosphatidic acid receptor by gintonin inhibits Kv1.2 channel activity: involvement of tyrosine kinase and receptor protein tyrosine phosphatase α., Lee JH, Choi SH, Lee BH, Hwang SH, Kim HJ, Rhee J, Chung C, Nah SY., Neurosci Lett. August 26, 2013; 548 143-8.
	Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels., Perry MD, Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.
	Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels., Arcangeletti M, Marchesi A, Mazzolini M, Torre V., Physiol Rep. November 1, 2013; 1 (6): e00148.
	Dynamic PIP2 interactions with voltage sensor elements contribute to KCNQ2 channel gating., Zhang Q, Zhou P, Chen Z, Li M, Jiang H, Gao Z, Yang H., Proc Natl Acad Sci U S A. December 10, 2013; 110 (50): 20093-8.
	Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process., Garneau L, Klein H, Lavoie MF, Brochiero E, Parent L, Sauvé R., J Gen Physiol. February 1, 2014; 143 (2): 289-307.

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