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Summary Expression Phenotypes Gene Literature (163) GO Terms (3) Nucleotides (613) Proteins (60) Interactants (996) Wiki
XB-GENEPAGE-966993

Papers associated with gmnn



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Measurement of geminin activity in Xenopus egg extracts., McGarry TJ., Methods Mol Biol. January 1, 2005; 296 263-78.

Functional domains of the Xenopus replication licensing factor Cdt1., Ferenbach A, Li A, Brito-Martins M, Blow JJ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.              

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., Maiorano D, Krasinska L, Lutzmann M, Mechali M., Curr Biol. January 26, 2005; 15 (2): 146-53.

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus., Li A, Blow JJ., EMBO J. January 26, 2005; 24 (2): 395-404.

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation., Tao J, Kuliyev E, Wang X, Li X, Wilanowski T, Jane SM, Mead PE, Cunningham JM., Development. March 1, 2005; 132 (5): 1021-34.        

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development., Yanagi K, Mizuno T, Tsuyama T, Tada S, Iida Y, Sugimoto A, Eki T, Enomoto T, Hanaoka F., J Biol Chem. May 20, 2005; 280 (20): 19689-94.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity., Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL., Genes Dev. July 15, 2005; 19 (14): 1723-34.      

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts., Leach CA, Michael WM., J Cell Biol. December 19, 2005; 171 (6): 947-54.                

Tcf- and Vent-binding sites regulate neural-specific geminin expression in the gastrula embryo., Taylor JJ, Wang T, Kroll KL., Dev Biol. January 15, 2006; 289 (2): 494-506.                

Regulation of replication licensing by acetyltransferase Hbo1., Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.

Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts., Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.

Subcellular translocation signals regulate Geminin activity during embryonic development., Boos A, Lee A, Thompson DM, Kroll KL., Biol Cell. June 1, 2006; 98 (6): 363-75.

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress., Woodward AM, Göhler T, Luciani MG, Oehlmann M, Ge X, Gartner A, Jackson DA, Blow JJ., J Cell Biol. June 5, 2006; 173 (5): 673-83.              

The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication., Matsuno K, Kumano M, Kubota Y, Hashimoto Y, Takisawa H., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.                

De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts., Zembutsu A, Waga S., Nucleic Acids Res. July 26, 2006; 34 (13): e91.          

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision., Davidson IF, Li A, Blow JJ., Mol Cell. November 3, 2006; 24 (3): 433-43.              

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus., Lutzmann M, Maiorano D, Méchali M., EMBO J. December 13, 2006; 25 (24): 5764-74.

Cdt1 and geminin: role during cell cycle progression and DNA damage in higher eukaryotes., Tada S., Front Biosci. January 1, 2007; 12 1629-41.

Geminin in embryonic development: coordinating transcription and the cell cycle during differentiation., Kroll KL., Front Biosci. January 1, 2007; 12 1395-409.

Geminin prevents rereplication during xenopus development., Kerns SL, Torke SJ, Benjamin JM, McGarry TJ., J Biol Chem. February 23, 2007; 282 (8): 5514-21.

Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts., Kumata Y, Tada S, Yamanada Y, Tsuyama T, Kobayashi T, Dong YP, Ikegami K, Murofushi H, Seki M, Enomoto T., Biochim Biophys Acta. April 1, 2007; 1773 (4): 556-64.

XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms., van Grunsven LA, Taelman V, Michiels C, Verstappen G, Souopgui J, Nichane M, Moens E, Opdecamp K, Vanhomwegen J, Kricha S, Huylebroeck D, Bellefroid EJ., Dev Biol. June 1, 2007; 306 (1): 34-49.            

Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, Galloway DA, Gu W, Gautier J, Dalla-Favera R., Nature. July 26, 2007; 448 (7152): 445-51.      

Geminin is cleaved by caspase-3 during apoptosis in Xenopus egg extracts., Auziol C, Méchali M, Maiorano D., Biochem Biophys Res Commun. September 21, 2007; 361 (2): 276-80.

Sox3 expression is maintained by FGF signaling and restricted to the neural plate by Vent proteins in the Xenopus embryo., Rogers CD, Archer TC, Cunningham DD, Grammer TC, Casey EM., Dev Biol. January 1, 2008; 313 (1): 307-19.                  

Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.              

Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition., Khoudoli GA, Gillespie PJ, Stewart G, Andersen JS, Swedlow JR, Blow JJ., Curr Biol. June 3, 2008; 18 (11): 838-43.        

MCM9 binds Cdt1 and is required for the assembly of prereplication complexes., Lutzmann M, Méchali M., Mol Cell. July 25, 2008; 31 (2): 190-200.

DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts., Labit H, Perewoska I, Germe T, Hyrien O, Marheineke K., Nucleic Acids Res. October 1, 2008; 36 (17): 5623-34.              

Cloning of Xenopus orthologs of Ctf7/Eco1 acetyltransferase and initial characterization of XEco2., Takagi M, Bunai K, Yanagi K, Imamoto N., FEBS J. December 1, 2008; 275 (24): 6109-22.

Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives., Rogers CD, Harafuji N, Archer T, Cunningham DD, Casey ES., Mech Dev. January 1, 2009; 126 (1-2): 42-55.        

Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts., Tsuyama T, Watanabe S, Aoki A, Cho Y, Seki M, Enomoto T, Tada S., Mol Biol Cell. February 1, 2009; 20 (3): 937-47.

Replication initiation complex formation in the absence of nuclear function in Xenopus., Krasinska L, Fisher D., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.            

foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation., Yan B, Neilson KM, Moody SA., Dev Biol. May 1, 2009; 329 (1): 80-95.              

Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation., Yan B, Neilson KM, Moody SA., Dev Dyn. June 1, 2009; 238 (6): 1358-65.        

Geminin stabilizes Cdt1 during meiosis in Xenopus oocytes., Narasimhachar Y, Coué M., J Biol Chem. October 2, 2009; 284 (40): 27235-42.

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing., De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 19807-12.

Origin-dependent initiation of DNA replication within telomeric sequences., Kurth I, Gautier J., Nucleic Acids Res. January 1, 2010; 38 (2): 467-76.          

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels., Thomson AM, Gillespie PJ, Blow JJ., J Cell Biol. January 25, 2010; 188 (2): 209-21.                  

Treslin collaborates with TopBP1 in triggering the initiation of DNA replication., Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell. February 5, 2010; 140 (3): 349-59.                        

Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail., Ohe M, Kawamura Y, Ueno H, Inoue D, Kanemori Y, Senoo C, Isoda M, Nakajo N, Sagata N., Mol Biol Cell. March 15, 2010; 21 (6): 905-13.            

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.        

G2 phase chromatin lacks determinants of replication timing., Lu J, Li F, Murphy CS, Davidson MW, Gilbert DM., J Cell Biol. June 14, 2010; 189 (6): 967-80.                

Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila., Herr A, Mckenzie L, Suryadinata R, Sadowski M, Parsons LM, Sarcevic B, Richardson HE., Dev Biol. August 1, 2010; 344 (1): 36-51.

Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction., Fan M, Buraei Z, Luo HR, Levenson-Palmer R, Yang J., Proc Natl Acad Sci U S A. August 17, 2010; 107 (33): 14887-92.

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

DNA is a co-factor for its own replication in Xenopus egg extracts., Lebofsky R, van Oijen AM, Walter JC., Nucleic Acids Res. January 1, 2011; 39 (2): 545-55.            

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo., Lim JW, Hummert P, Mills JC, Kroll KL., Development. January 1, 2011; 138 (1): 33-44.                    

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