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Summary Expression Phenotypes Gene Literature (274) GO Terms (11) Nucleotides (367) Proteins (70) Interactants (922) Wiki
XB-GENEPAGE-968717

Papers associated with myh6



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Larval T Cells Are Functionally Distinct from Adult T Cells in Xenopus laevis., Paiola M, McGuire CC, Lopez Ruiz V, De Jesús Andino F, Robert J., Immunohorizons. October 1, 2023; 7 (10): 696-707.                

A perspective into the relationships between amphibian (Xenopus laevis) myeloid cell subsets., Hossainey MRH, Hauser KA, Garvey CN, Kalia N, Garvey JM, Grayfer L., Philos Trans R Soc Lond B Biol Sci. July 31, 2023; 378 (1882): 20220124.

Divergent allele advantage in the MHC and amphibian emerging infectious disease., Fu M, Eimes JA, Waldman B., Infect Genet Evol. July 1, 2023; 111 105429.            

Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation., Schroeter CB, Nelke C, Schewe M, Spohler L, Herrmann AM, Müntefering T, Huntemann N, Kuzikov M, Gribbon P, Albrecht S, Bock S, Hundehege P, Neelsen LC, Baukrowitz T, Seebohm G, Wünsch B, Bittner S, Ruck T, Budde T, Meuth SG., Biol Chem. March 28, 2023; 404 (4): 355-375.              

Evolution and Potential Subfunctionalization of Duplicated fms-Related Class III Receptor Tyrosine Kinase flt3s and Their Ligands in the Allotetraploid Xenopus laevis., Paiola M, Ma S, Robert J., J Immunol. September 1, 2022; 209 (5): 960-969.

Inducible and tissue-specific cell labeling in Cre-ERT2 transgenic Xenopus lines., Lin TY, Taniguchi-Sugiura Y, Murawala P, Hermann S, Tanaka EM., Dev Growth Differ. June 1, 2022; 64 (5): 243-253.        

Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians., Shook DR, Wen JWH, Rolo A, O'Hanlon M, Francica B, Dobbins D, Skoglund P, DeSimone DW, Winklbauer R, Keller RE., Elife. April 11, 2022; 11                                     

Impact of glyphosate-based herbicide on early embryonic development of the amphibian Xenopus laevis., Flach H, Lenz A, Pfeffer S, Kühl M, Kühl SJ., Aquat Toxicol. March 1, 2022; 244 106081.

Developmental exposure to thyroid disrupting chemical mixtures alters metamorphosis and post-metamorphic thymocyte differentiation., McGuire CC, Robert JR., Curr Res Toxicol. January 1, 2022; 3 100094.

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.                        

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue., Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S., Curr Biol. August 9, 2021; 31 (15): 3409-3418.e6.                  

A Highly Complex, MHC-Linked, 350 Million-Year-Old Shark Nonclassical Class I Lineage., Almeida T, Ohta Y, Gaigher A, Muñoz-Mérida A, Neves F, Castro LFC, Machado AM, Esteves PJ, Veríssimo A, Flajnik MF., J Immunol. August 1, 2021; 207 (3): 824-836.

Preliminary indications that recombinant human IL-16 attracts and stimulates lymphocytes of the amphibian, Xenopus laevis implying an ancestral role for CD4 as a cytokine receptor., Gillis J, Uccello TP, Magri Z, Morris N, Maniero GD., Cytokine. December 1, 2020; 136 155254.

Anatomical and histological analyses reveal that tail repair is coupled with regrowth in wild-caught, juvenile American alligators (Alligator mississippiensis)., Xu C, Palade J, Fisher RE, Smith CI, Clark AR, Sampson S, Bourgeois R, Rawls A, Elsey RM, Wilson-Rawls J, Kusumi K., Sci Rep. November 18, 2020; 10 (1): 20122.                

rad21 Is Involved in Corneal Stroma Development by Regulating Neural Crest Migration., Zhang BN, Liu Y, Yang Q, Leung PY, Wang C, Wang C, Wang C, Wong TCB, Tham CC, Chan SO, Pang CP, Chen LJ, Dekker J, Zhao H, Chu WK., Int J Mol Sci. October 21, 2020; 21 (20):                             

Disabled-2: a positive regulator of the early differentiation of myoblasts., Shang N, Lee JTY, Huang T, Wang C, Wang C, Lee TL, Mok SC, Zhao H, Chan WY., Cell Tissue Res. September 1, 2020; 381 (3): 493-508.                              

The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Aztekin C, Hiscock TW, Butler R, De Jesús Andino F, Robert J, Gurdon JB, Jullien J., Development. February 5, 2020; 147 (3):                                     

Expression Changes of MHC and Other Immune Genes in Frog Skin during Ontogeny., Lau Q, Igawa T, Komaki S, Satta Y., Animals (Basel). January 6, 2020; 10 (1):         

A Glimpse of the Peptide Profile Presentation by Xenopus laevis MHC Class I: Crystal Structure of pXela-UAA Reveals a Distinct Peptide-Binding Groove., Ma L, Zhang N, Qu Z, Liang R, Zhang L, Zhang B, Meng G, Dijkstra JM, Li S, Xia MC., J Immunol. January 1, 2020; 204 (1): 147-158.

Inferring the "Primordial Immune Complex": Origins of MHC Class I and Antigen Receptors Revealed by Comparative Genomics., Ohta Y, Kasahara M, O'Connor TD, Flajnik MF., J Immunol. October 1, 2019; 203 (7): 1882-1896.

Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus., Banach M, Edholm ES, Gonzalez X, Benraiss A, Robert J., Carcinogenesis. July 20, 2019; 40 (7): 924-935.

Vangl2 coordinates cell rearrangements during gut elongation., Dush MK, Nascone-Yoder NM., Dev Dyn. July 1, 2019; 248 (7): 569-582.                

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Schwenty-Lara J, Nürnberger A, Borchers A., Dev Dyn. June 1, 2019; 248 (6): 465-476.                  

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation., Segovia M, Russo S, Jeldres M, Mahmoud YD, Perez V, Duhalde M, Charnet P, Rousset M, Victoria S, Veigas F, Louvet C, Vanhove B, Floto RA, Anegon I, Cuturi MC, Girotti MR, Rabinovich GA, Hill M., Cancer Cell. May 13, 2019; 35 (5): 767-781.e6.                                          

Skin Grafting in Xenopus laevis: A Technique for Assessing Development and Immunological Disparity., Izutsu Y., Cold Spring Harb Protoc. May 1, 2019; 2019 (5):


The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M., Dev Biol. May 1, 2019; 449 (1): 1-13.                                  

Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection., Edholm EI, De Jesús Andino F, Yim J, Woo K, Robert J., Viruses. April 6, 2019; 11 (4):                 

A Xenopus tadpole alternative model to study innate-like T cell-mediated anti-mycobacterial immunity., Hyoe RK, Robert J., Dev Comp Immunol. March 1, 2019; 92 253-259.

Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Haworth K, Samuel L, Black S, Kirilenko P, Latinkic B., Front Physiol. January 1, 2019; 10 155.              

Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies., Deniz E, Jonas S, Khokha MK, Choma MA., Front Physiol. January 1, 2019; 10 1197.      

A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in NOD Mice., Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV., J Immunol. October 1, 2018; 201 (7): 1907-1917.

CRISPR/Cas9-mediated efficient and precise targeted integration of donor DNA harboring double cleavage sites in Xenopus tropicalis., Mao CZ, Zheng L, Zhou YM, Wu HY, Xia JB, Liang CQ, Guo XF, Peng WT, Zhao H, Cai WB, Kim SK, Park KS, Cai DQ, Qi XF., FASEB J. June 13, 2018; fj201800093.              

Distinct MHC class I-like interacting invariant T cell lineage at the forefront of mycobacterial immunity uncovered in Xenopus., Edholm ES, Banach M, Hyoe Rhoo K, Pavelka MS, Robert J., Proc Natl Acad Sci U S A. April 24, 2018; 115 (17): E4023-E4031.          

Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus., Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC., Dev Cell. March 12, 2018; 44 (5): 597-610.e10.                                            

"Double-duty" conventional dendritic cells in the amphibian Xenopus as the prototype for antigen presentation to B cells., Neely HR, Guo J, Flowers EM, Criscitiello MF, Flajnik MF., Eur J Immunol. March 1, 2018; 48 (3): 430-440.

Id genes are essential for early heart formation., Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR., Genes Dev. July 1, 2017; 31 (13): 1325-1338.                

Exploring the functions of nonclassical MHC class Ib genes in Xenopus laevis by the CRISPR/Cas9 system., Banach M, Edholm ES, Robert J., Dev Biol. June 15, 2017; 426 (2): 261-269.          

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis., Hempel A, Kühl SJ, Rothe M, Rao Tata P, Sirbu IO, Vainio SJ, Kühl M., Dev Biol. April 1, 2017; 424 (1): 28-39.                                  

Tumor immunology viewed from alternative animal models-the Xenopus story., Banach M, Robert J., Curr Pathobiol Rep. March 1, 2017; 5 (1): 49-56.

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography., Deniz E, Jonas S, Hooper M, N Griffin J, Choma MA, Khokha MK., Sci Rep. February 14, 2017; 7 42506.          

Genome evolution in the allotetraploid frog Xenopus laevis., Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS., Nature. October 20, 2016; 538 (7625): 336-343.                              

Evolution of innate-like T cells and their selection by MHC class I-like molecules., Edholm ES, Banach M, Robert J., Immunogenetics. August 1, 2016; 68 (8): 525-36.

Molecular model for force production and transmission during vertebrate gastrulation., Pfister K, Shook DR, Chang C, Keller R, Skoglund P., Development. February 15, 2016; 143 (4): 715-27.              

A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts., Tanaka HV, Ng NC, Yang Yu Z, Casco-Robles MM, Maruo F, Tsonis PA, Chiba C., Nat Commun. January 12, 2016; 7 11069.        

Copy number variation and genetic diversity of MHC Class IIb alleles in an alien population of Xenopus laevis., Mable BK, Kilbride E, Viney ME, Tinsley RC., Immunogenetics. October 1, 2015; 67 (10): 591-603.    

A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation., Jang DG, Sim HJ, Song EK, Medina-Ruiz S, Seo JK, Park TJ., Dev Biol. September 1, 2015; 405 (1): 1-9.                                    

Coevolution of MHC genes (LMP/TAP/class Ia, NKT-class Ib, NKp30-B7H6): lessons from cold-blooded vertebrates., Ohta Y, Flajnik MF., Immunol Rev. September 1, 2015; 267 (1): 6-15.

Nonclassical MHC-Restricted Invariant Vα6 T Cells Are Critical for Efficient Early Innate Antiviral Immunity in the Amphibian Xenopus laevis., Edholm ES, Grayfer L, De Jesús Andino F, Robert J., J Immunol. July 15, 2015; 195 (2): 576-86.

Contractile activity is required for Z-disc sarcomere maturation in vivo., Geach TJ, Hirst EM, Zimmerman LB., Genesis. May 1, 2015; 53 (5): 299-307.                

Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity., Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A., Stem Cells. April 1, 2015; 33 (4): 1113-29.              

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