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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB-GENEPAGE-489467

Papers associated with ran



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Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2., Hu W, Jans DA., J Biol Chem. May 28, 1999; 274 (22): 15820-7.


Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts., Zhang C, Hughes M, Clarke PR., J Cell Sci. July 1, 1999; 112 ( Pt 14) 2453-61.


Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation., Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW., Nature. July 8, 1999; 400 (6740): 178-81.


A new role of ran GTPase., Nishimoto T., Biochem Biophys Res Commun. September 7, 1999; 262 (3): 571-4.


Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly., Kahana JA, Cleveland DW., J Cell Biol. September 20, 1999; 146 (6): 1205-10.    


Microtubule cytoskeleton: No longer an also Ran., Desai A, Hyman A., Curr Biol. September 23, 1999; 9 (18): R704-7.


Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer., Adachi M, Fukuda M, Nishida E., EMBO J. October 1, 1999; 18 (19): 5347-58.


Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle., Fischer U, Pollard VW, Lührmann R, Teufel M, Michael MW, Dreyfuss G, Malim MH., Nucleic Acids Res. November 1, 1999; 27 (21): 4128-34.


The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates., Bachi A, Braun IC, Rodrigues JP, Panté N, Ribbeck K, von Kobbe C, Kutay U, Wilm M, Görlich D, Carmo-Fonseca M, Izaurralde E., RNA. January 1, 2000; 6 (1): 136-58.


The targeting of Xcat2 mRNA to the germinal granules depends on a cis-acting germinal granule localization element within the 3'UTR., Kloc M, Bilinski S, Pui-Yee Chan A, Etkin LD., Dev Biol. January 15, 2000; 217 (2): 221-9.          


The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip., Talcott B, Moore MS., J Biol Chem. April 7, 2000; 275 (14): 10099-104.


Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts., Zhang C, Clarke PR., Science. May 26, 2000; 288 (5470): 1429-32.


Expression of the Xenopus GTP-binding protein gene Ran during embryogenesis., Onuma Y, Nishihara R, Takahashi S, Tanegashima K, Fukui A, Asashima M., Dev Genes Evol. June 1, 2000; 210 (6): 325-7.


Nuclear transport of histone 2b in mammalian cells is signal- and energy-dependent and different from the importin alpha/beta-mediated process., Langer T., Histochem Cell Biol. June 1, 2000; 113 (6): 455-65.


GTP hydrolysis by Ran is required for nuclear envelope assembly., Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW., Mol Cell. June 1, 2000; 5 (6): 1013-24.


Structure and expression of Xenopus karyopherin-beta3: definition of a novel synexpression group related to ribosome biogenesis., Wischnewski J, Sölter M, Chen Y, Chen Y, Hollemann T, Pieler T., Mech Dev. July 1, 2000; 95 (1-2): 245-8.                            


RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro., Ossareh-Nazari B, Maison C, Black BE, Lévesque L, Paschal BM, Dargemont C., Mol Cell Biol. July 1, 2000; 20 (13): 4562-71.


Ran alters nuclear pore complex conformation., Goldberg MW, Goldberg MW, Rutherford SA, Hughes M, Cotter LA, Bagley S, Kiseleva E, Allen TD, Clarke PR., J Mol Biol. July 14, 2000; 300 (3): 519-29.


Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo., Guarguaglini G, Renzi L, D'Ottavio F, Di Fiore B, Casenghi M, Cundari E, Lavia P., Cell Growth Differ. August 1, 2000; 11 (8): 455-65.


Purification of the vertebrate nuclear pore complex by biochemical criteria., Miller BR, Forbes DJ., Traffic. December 1, 2000; 1 (12): 941-51.


A Ran-independent pathway for export of spliced mRNA., Clouse KN, Luo MJ, Zhou Z, Reed R., Nat Cell Biol. January 1, 2001; 3 (1): 97-9.


CRM1- and Ran-independent nuclear export of beta-catenin., Wiechens N, Fagotto F., Curr Biol. January 9, 2001; 11 (1): 18-27.


Importin beta is a mitotic target of the small GTPase Ran in spindle assembly., Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K., Cell. January 12, 2001; 104 (1): 95-106.


Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity., Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW., Cell. January 12, 2001; 104 (1): 83-93.


Role of importin-beta in coupling Ran to downstream targets in microtubule assembly., Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y., Science. January 26, 2001; 291 (5504): 653-6.


Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system., Zhang C, Clarke PR., Curr Biol. February 6, 2001; 11 (3): 208-12.


Ran hits the ground running., Walczak CE., Nat Cell Biol. March 1, 2001; 3 (3): E69-70.


Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly., Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E., Nat Cell Biol. March 1, 2001; 3 (3): 228-34.


Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities., Wilde A, Lizarraga SB, Zhang L, Wiese C, Gliksman NR, Walczak CE, Zheng Y., Nat Cell Biol. March 1, 2001; 3 (3): 221-7.


Ran GTPase cycle: oOne mechanism -- two functions., Melchior F., Curr Biol. April 3, 2001; 11 (7): R257-60.


Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B., Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG., Science. May 25, 2001; 292 (5521): 1540-3.


Ran binding protein RanBP1 in zebrafish embryonic development., Mangos S, Vanderbeld B, Krawetz R, Sudol K, Kelly GM., Mol Reprod Dev. July 1, 2001; 59 (3): 235-48.


A light microscope study of the distribution of muscle in the frog esophagus and stomach., Yoshida M., J Smooth Muscle Res. August 1, 2001; 37 (3-4): 95-104.


XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP., Nicolás FJ, Moore WJ, Zhang C, Clarke PR., J Cell Sci. August 1, 2001; 114 (Pt 16): 3013-23.


Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5., Rudt F, Pieler T., Eur J Cell Biol. November 1, 2001; 80 (11): 661-8.


Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly., Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW., Nat Cell Biol. December 1, 2001; 3 (12): 1086-91.


Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry., Machaca K, Haun S., J Cell Biol. January 7, 2002; 156 (1): 75-85.                


The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo., Bamba C, Bobinnec Y, Fukuda M, Nishida E., Curr Biol. March 19, 2002; 12 (6): 503-7.


Role of importin-beta in the control of nuclear envelope assembly by Ran., Zhang C, Hutchins JR, Mühlhäusser P, Kutay U, Clarke PR., Curr Biol. March 19, 2002; 12 (6): 498-502.


Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts., Kalab P, Weis K, Heald R., Science. March 29, 2002; 295 (5564): 2452-6.


The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form., Nilsson J, Weis K, Kjems J., J Mol Biol. April 26, 2002; 318 (2): 583-93.


Ran binds to chromatin by two distinct mechanisms., Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW., Curr Biol. July 9, 2002; 12 (13): 1151-6.


Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains., Kuersten S, Arts GJ, Walther TC, Englmeier L, Mattaj IW., Mol Cell Biol. August 1, 2002; 22 (16): 5708-20.


Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells., Moore W, Zhang C, Clarke PR., Curr Biol. August 20, 2002; 12 (16): 1442-7.


Reconstitution of nuclear protein export in isolated nuclear envelopes., Siebrasse JP, Coutavas E, Peters R., J Cell Biol. September 2, 2002; 158 (5): 849-54.          


Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1)., Wildman SS, Brown SG, Rahman M, Noel CA, Churchill L, Burnstock G, Unwin RJ, King BF., Mol Pharmacol. October 1, 2002; 62 (4): 957-66.


Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly., Zhang C, Goldberg MW, Goldberg MW, Moore WJ, Allen TD, Clarke PR., Eur J Cell Biol. November 1, 2002; 81 (11): 623-33.


Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells., Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Silljé H, Karsenti E, Mattaj IW, Vernos I., Nat Cell Biol. November 1, 2002; 4 (11): 871-9.


Differences in apparent pore sizes of low and high voltage-activated Ca2+ channels., Cataldi M, Perez-Reyes E, Tsien RW., J Biol Chem. November 29, 2002; 277 (48): 45969-76.


Chromosomal association of Ran during meiotic and mitotic divisions., Hinkle B, Slepchenko B, Rolls MM, Walther TC, Stein PA, Mehlmann LM, Ellenberg J, Terasaki M., J Cell Sci. December 1, 2002; 115 (Pt 23): 4685-93.

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