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Summary Expression Phenotypes Gene Literature (96) GO Terms (5) Nucleotides (93) Proteins (44) Interactants (546) Wiki
XB-GENEPAGE-998105

Papers associated with pik3ca



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Temporal and spatial transcriptomic dynamics across brain development in Xenopus laevis tadpoles., Ta AC, Huang LC, McKeown CR, Bestman JE, Van Keuren-Jensen K, Cline HT., G3 (Bethesda). January 4, 2022; 12 (1):               

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB, Willsey HR, Xu Y, Xu Y, Mei Y, Dea J, Wang S, Curtis C, Sempou E, Khokha MK, Chi NC, Willsey AJ, Fisch KM, Ideker T., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.            

Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion., Cai R, Wang L, Liu X, Michalak M, Tang J, Peng JB, Chen XZ., Commun Biol. August 19, 2021; 4 (1): 990.              

A direct role for SNX9 in the biogenesis of filopodia., Jarsch IK, Gadsby JR, Nuccitelli A, Mason J, Shimo H, Pilloux L, Marzook B, Mulvey CM, Dobramysl U, Bradshaw CR, Lilley KS, Hayward RD, Vaughan TJ, Dobson CL, Gallop JL., J Cell Biol. April 6, 2020; 219 (4):               

The Expression of Key Guidance Genes at a Forebrain Axon Turning Point Is Maintained by Distinct Fgfr Isoforms but a Common Downstream Signal Transduction Mechanism., Yang JJ, Bertolesi GE, Dueck S, Hehr CL, McFarlane S., eNeuro. April 9, 2019; 6 (2):                   

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.          

Palmitate Stimulates the Epithelial Sodium Channel by Elevating Intracellular Calcium, Reactive Oxygen Species, and Phosphoinositide 3-Kinase Activity., Wang QS, Liang C, Niu N, Yang X, Chen X, Song BL, Yu CJ, Wu MM, Zhang ZR, Ma HP., Oxid Med Cell Longev. December 2, 2018; 2018 7560610.                  

Aminophylline and Ephedrine, but Not Flumazenil, Inhibit the Activity of the Excitatory Amino Acid Transporter 3 Expressed in Xenopus Oocytes and Reverse the Increased Activity by Propofol., Moon S, Baik HJ., Biomed Res Int. May 20, 2018; 2018 6817932.                

FGF mediated MAPK and PI3K/Akt Signals make distinct contributions to pluripotency and the establishment of Neural Crest., Geary L, LaBonne C., Elife. January 19, 2018; 7                     

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases., Andersen MN, Skibsbye L, Saljic A, Larsen MZ, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2018; 12 (1): 34-44.              

The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration., Mathavan K, Khedgikar V, Bartolo V, Alfandari D, Alfandari D., PLoS One. November 30, 2017; 12 (11): e0188963.                        

PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH., Development. November 15, 2017; 144 (22): 4183-4194.                                

Insulin treatment augments KCNQ1/KCNE1 currents but not KCNQ1 currents, which is associated with an increase in KCNE1 expression., Wu M, Obara Y, Ohshima S, Nagasawa Y, Ishii K., Biochem Biophys Res Commun. November 4, 2017; 493 (1): 409-415.

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Gabapentin inhibits the activity of the rat excitatory glutamate transporter 3 expressed in Xenopus oocytes., Gil YS, Kim JH, Kim CH, Han JI, Zuo Z, Baik HJ., Eur J Pharmacol. September 5, 2015; 762 112-7.

The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells., La Torre A, Hoshino A, Cavanaugh C, Ware CB, Reh TA., Stem Cells. September 1, 2015; 33 (9): 2674-85.

Desflurane increased the activity of excitatory amino-acid carrier 1 (EAAC1) expressed in Xenopus oocytes., Park SJ, Shin HJ, Gu BW, Woo KI, Zuo Z, Do SH, Ryu JH., Eur J Pharmacol. June 15, 2015; 757 84-9.

Differential regulation of Connexin50 and Connexin46 by PI3K signaling., Martinez JM, Wang HZ, Lin RZ, Brink PR, White TW., FEBS Lett. May 22, 2015; 589 (12): 1340-5.

Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones., Piper M, Lee AC, van Horck FP, McNeilly H, Lu TB, Harris WA, Holt CE., Neural Dev. February 25, 2015; 10 3.            

Hydrogen Sulfide Prevents Advanced Glycation End-Products Induced Activation of the Epithelial Sodium Channel., Wang Q, Song B, Jiang S, Liang C, Chen X, Shi J, Li X, Sun Y, Wu M, Zhao D, Zhang ZR, Ma HP., Oxid Med Cell Longev. January 1, 2015; 2015 976848.            

Insulin is involved in transcriptional regulation of NKCC and the CFTR Cl(-) channel through PI3K activation and ERK inactivation in renal epithelial cells., Sun H, Niisato N, Inui T, Marunaka Y., J Physiol Sci. November 1, 2014; 64 (6): 433-43.

EphA4-dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula., Evren S, Wen JW, Luu O, Damm EW, Nagel M, Winklbauer R., Development. October 1, 2014; 141 (19): 3649-61.                              

Dexmedetomidine increases the activity of excitatory amino acid transporter type 3 expressed in Xenopus oocytes: the involvement of protein kinase C and phosphatidylinositol 3-kinase., Do SH, Park SJ, Shin HJ, Paik HS, Zuo Z, Yoon HJ, Ryu JH., Eur J Pharmacol. September 5, 2014; 738 8-13.

Ondansetron attenuates the activity of excitatory amino acid transporter type 3 expressed in Xenopus oocytes., Hur W, Lee MK, Park HP, Kim CS, Yoon HJ, Zuo Z, Do SH., Eur J Pharmacol. June 15, 2014; 733 7-12.

Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos., Chatfield J, O'Reilly MA, Bachvarova RF, Ferjentsik Z, Redwood C, Walmsley M, Patient R, Loose M, Johnson AD., Development. June 1, 2014; 141 (12): 2429-40.              

Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoni., Vanderstraete M, Gouignard N, Cailliau K, Morel M, Hahnel S, Leutner S, Beckmann S, Grevelding CG, Dissous C., PLoS Pathog. May 29, 2014; 10 (5): e1004138.              

Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1., Wu M, Obara Y, Norota I, Nagasawa Y, Ishii K., Pflugers Arch. May 1, 2014; 466 (5): 937-46.

Nicotine decreases the activity of glutamate transporter type 3., Yoon HJ, Lim YJ, Zuo Z, Hur W, Do SH., Toxicol Lett. February 10, 2014; 225 (1): 147-52.

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways., Feng Y, Williams BG, Koumanov F, Wolstenholme AJ, Holman GD., Biochem J. December 1, 2013; 456 (2): 219-29.            

ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healing., Li J, Zhang S, Soto X, Woolner S, Amaya E., J Cell Sci. November 1, 2013; 126 (Pt 21): 5005-17.              

Progesterone increases the activity of glutamate transporter type 3 expressed in Xenopus oocytes., Son I, Shin HJ, Ryu JH, Kim HK, Do SH, Zuo Z., Eur J Pharmacol. September 5, 2013; 715 (1-3): 414-9.

Characterization of the first honeybee Ca²⁺ channel subunit reveals two novel species- and splicing-specific modes of regulation of channel inactivation., Cens T, Rousset M, Collet C, Raymond V, Démares F, Quintavalle A, Bellis M, Le Conte Y, Chahine M, Charnet P., Pflugers Arch. July 1, 2013; 465 (7): 985-96.

In vivo and in vitro anti-natriuretic activity of twigs fraction from Dorstenia picta: a possible mechanism., Florence NT, Nicolas M, Raphael C, Hubert DJ, Etienne D, Pierre K, Theophile D, Renaud B., Pak J Pharm Sci. May 1, 2013; 26 (3): 537-45.

Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway., Figueroa V, Sáez PJ, Salas JD, Salas D, Jara O, Martínez AD, Sáez JC, Retamal MA., Biochim Biophys Acta. March 1, 2013; 1828 (3): 1169-79.

Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes., Shin HJ, Ryu JH, Kim ST, Zuo Z, Do SH., Toxicol Lett. February 27, 2013; 217 (2): 143-8.

Downregulation of the renal outer medullary K(+) channel ROMK by the AMP-activated protein kinase., Siraskar B, Huang DY, Pakladok T, Siraskar G, Sopjani M, Alesutan I, Kucherenko Y, Almilaji A, Devanathan V, Shumilina E, Föller M, Munoz C, Lang F., Pflugers Arch. February 1, 2013; 465 (2): 233-45.

Insulin increases the functional activity of the renal NaCl cotransporter., Chávez-Canales M, Arroyo JP, Ko B, Vázquez N, Bautista R, Castañeda-Bueno M, Bobadilla NA, Hoover RS, Gamba G., J Hypertens. February 1, 2013; 31 (2): 303-11.

A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis., Zhang S, Li J, Lea R, Amaya E, Dorey K., PLoS One. January 1, 2013; 8 (11): e79469.              

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.                      

The translational repressor 4E-BP mediates hypoxia-induced defects in myotome cells., Hidalgo M, Le Bouffant R, Bello V, Buisson N, Cormier P, Beaudry M, Darribère T., J Cell Sci. September 1, 2012; 125 (Pt 17): 3989-4000.            

Effects of pregabalin on the activity of glutamate transporter type 3., Ryu JH, Lee PB, Kim JH, Do SH, Kim CS., Br J Anaesth. August 1, 2012; 109 (2): 234-9.

17β-Estradiol attenuates the activity of the glutamate transporter type 3 expressed in Xenopus oocytes., Na HS, Park HP, Kim CS, Do SH, Zuo Z, Kim CS., Eur J Pharmacol. February 15, 2012; 676 (1-3): 20-5.

Roles of major facilitator superfamily transporters in phosphate response in Drosophila., Bergwitz C, Rasmussen MD, DeRobertis C, Wee MJ, Sinha S, Chen HH, Huang J, Perrimon N., PLoS One. January 1, 2012; 7 (2): e31730.        

Role of the PI3K-TOR-S6K pathway in the onset of cell cycle elongation during Xenopus early embryogenesis., Ueno S, Ueno T, Iwao Y., Dev Growth Differ. October 1, 2011; 53 (8): 924-33.

Hydrogen peroxide stimulates the epithelial sodium channel through a phosphatidylinositide 3-kinase-dependent pathway., Ma HP., J Biol Chem. September 16, 2011; 286 (37): 32444-53.

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition., Walsh LA, Damjanovski S., Cell Commun Signal. May 2, 2011; 9 (1): 10.            

A new in vitro system for activating the cell cycle checkpoint., Wang J, Engle S, Zhang Y, Zhang Y., Cell Cycle. February 1, 2011; 10 (3): 500-6.

The kinase SGK1 in the endoderm and mesoderm promotes ectodermal survival by down-regulating components of the death-inducing signaling complex., Endo T, Kusakabe M, Sunadome K, Yamamoto T, Nishida E., Sci Signal. January 18, 2011; 4 (156): ra2.

Presynaptic protein synthesis required for NT-3-induced long-term synaptic modulation., Je HS, Ji Y, Wang Y, Yang F, Wu W, Lu B., Mol Brain. January 7, 2011; 4 1.        

Corticosterone decreases the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes., Kang M, Ryu J, Kim JH, Na H, Zuo Z, Do SH., Steroids. December 12, 2010; 75 (13-14): 1113-8.

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