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Summary Expression Phenotypes Gene Literature (229) GO Terms (4) Nucleotides (67) Proteins (40) Interactants (939) Wiki
XB--853107

Papers associated with en2 (and morpholino)



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G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          


G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          


NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo., Zhu X, Min Z, Tan R, Tao Q, Tao Q., Mech Dev. November 1, 2015; 138 Pt 3 305-12.                


NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo., Zhu X, Min Z, Tan R, Tao Q, Tao Q., Mech Dev. November 1, 2015; 138 Pt 3 305-12.                


RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development., Pfirrmann T, Villavicencio-Lorini P, Subudhi AK, Menssen R, Wolf DH, Hollemann T., PLoS One. March 16, 2015; 10 (3): e0120342.                      


RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development., Pfirrmann T, Villavicencio-Lorini P, Subudhi AK, Menssen R, Wolf DH, Hollemann T., PLoS One. March 16, 2015; 10 (3): e0120342.                      


The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    


The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    


A novel function for Egr4 in posterior hindbrain development., Bae CJ, Jeong J, Saint-Jeannet JP., Sci Rep. January 12, 2015; 5 7750.                              


A novel function for Egr4 in posterior hindbrain development., Bae CJ, Jeong J, Saint-Jeannet JP., Sci Rep. January 12, 2015; 5 7750.                              


Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    


Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                


Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                


Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        


Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                


The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube., Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Van Driessche B, Brandão Kde O, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Van Lint C, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ., Dev Biol. February 15, 2014; 386 (2): 340-57.                                                                    


The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube., Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Van Driessche B, Brandão Kde O, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Van Lint C, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ., Dev Biol. February 15, 2014; 386 (2): 340-57.                                                                    


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            


FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              


FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              


Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning., Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H., J Biol Chem. November 1, 2013; 288 (44): 31477-87.                    


Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning., Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H., J Biol Chem. November 1, 2013; 288 (44): 31477-87.                    


Loss of Xenopus cadherin-11 leads to increased Wnt/β-catenin signaling and up-regulation of target genes c-myc and cyclin D1 in neural crest., Koehler A, Schlupf J, Schneider M, Kraft B, Winter C, Kashef J., Dev Biol. November 1, 2013; 383 (1): 132-45.                        


The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            


The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors., Klingel S, Morath I, Strietz J, Menzel K, Holstein TW, Gradl D., Dev Biol. August 1, 2012; 368 (1): 44-53.              


Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors., Klingel S, Morath I, Strietz J, Menzel K, Holstein TW, Gradl D., Dev Biol. August 1, 2012; 368 (1): 44-53.              


ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development., Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M., Cell Rep. May 31, 2012; 1 (5): 516-27.                              


ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development., Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M., Cell Rep. May 31, 2012; 1 (5): 516-27.                              


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            


The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            


A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      


A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      


Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  


Xenopus laevis insulin receptor substrate IRS-1 is important for eye development., Bugner V, Aurhammer T, Kühl M., Dev Dyn. July 1, 2011; 240 (7): 1705-15.            


Notch destabilises maternal beta-catenin and restricts dorsal-anterior development in Xenopus., Acosta H, López SL, Revinski DR, Carrasco AE., Development. June 1, 2011; 138 (12): 2567-79.                          


Polypyrimidine tract-binding protein is required for the repression of gene expression by all-trans retinoic acid., Tamanoue Y, Yamagishi M, Hongo I, Okamoto H., Dev Growth Differ. June 1, 2010; 52 (5): 469-79.                    


Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2., Guiral EC, Faas L, Pownall ME., Dev Biol. May 15, 2010; 341 (2): 375-88.                              


Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2., Guiral EC, Faas L, Pownall ME., Dev Biol. May 15, 2010; 341 (2): 375-88.                              


The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    


The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    


En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain., Koenig SF, Brentle S, Hamdi K, Fichtner D, Wedlich D, Gradl D., Dev Biol. April 15, 2010; 340 (2): 318-28.                  


En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain., Koenig SF, Brentle S, Hamdi K, Fichtner D, Wedlich D, Gradl D., Dev Biol. April 15, 2010; 340 (2): 318-28.                  


Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            


Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus., Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM., Dev Biol. January 15, 2010; 337 (2): 335-50.                  


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus., Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM., Dev Biol. January 15, 2010; 337 (2): 335-50.                  


Frizzled-10 promotes sensory neuron development in Xenopus embryos., Garcia-Morales C, Liu CH, Abu-Elmagd M, Hajihosseini MK, Wheeler GN., Dev Biol. November 1, 2009; 335 (1): 143-55.        


The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction., Li B, Kuriyama S, Moreno M, Mayor R., Development. October 1, 2009; 136 (19): 3267-78.            


The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction., Li B, Kuriyama S, Moreno M, Mayor R., Development. October 1, 2009; 136 (19): 3267-78.            


Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus., Thomas JT, Canelos P, Luyten FP, Moos M., J Biol Chem. July 10, 2009; 284 (28): 18994-9005.                    


The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                


The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                


Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal., Rhinn M, Lun K, Ahrendt R, Geffarth M, Brand M., Neural Dev. April 2, 2009; 4 12.              


Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system., Strate I, Min TH, Iliev D, Pera EM., Development. February 1, 2009; 136 (3): 461-72.                


Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system., Strate I, Min TH, Iliev D, Pera EM., Development. February 1, 2009; 136 (3): 461-72.                


The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo., Hou S, Maccarana M, Min TH, Strate I, Pera EM., Dev Cell. August 1, 2007; 13 (2): 226-41.                      


The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo., Hou S, Maccarana M, Min TH, Strate I, Pera EM., Dev Cell. August 1, 2007; 13 (2): 226-41.                      


The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions., Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG., Dev Biol. July 15, 2007; 307 (2): 483-97.        


The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions., Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG., Dev Biol. July 15, 2007; 307 (2): 483-97.        


The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              


The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways., Yan B, Moody SA., Dev Biol. May 1, 2007; 305 (1): 103-19.        


The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways., Yan B, Moody SA., Dev Biol. May 1, 2007; 305 (1): 103-19.        


Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway., Alexandrova EM, Thomsen GH., Dev Biol. November 15, 2006; 299 (2): 398-410.                      


Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway., Alexandrova EM, Thomsen GH., Dev Biol. November 15, 2006; 299 (2): 398-410.                      


Xenopus Teashirt1 regulates posterior identity in brain and cranial neural crest., Koebernick K, Kashef J, Pieler T, Wedlich D., Dev Biol. October 1, 2006; 298 (1): 312-26.                              


Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling., Heeg-Truesdell E, LaBonne C., Dev Biol. October 1, 2006; 298 (1): 71-86.                    


Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling., Heeg-Truesdell E, LaBonne C., Dev Biol. October 1, 2006; 298 (1): 71-86.                    


Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    


Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    


Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning., Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK., Dev Dyn. July 1, 2006; 235 (7): 1895-907.                            


Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development., Morrison GM, Brickman JM., Development. May 1, 2006; 133 (10): 2011-22.                


Tes regulates neural crest migration and axial elongation in Xenopus., Dingwell KS, Smith JC., Dev Biol. May 1, 2006; 293 (1): 252-67.                          


Tes regulates neural crest migration and axial elongation in Xenopus., Dingwell KS, Smith JC., Dev Biol. May 1, 2006; 293 (1): 252-67.                          


Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis., Peres JN, McNulty CL, Durston AJ., Mech Dev. April 1, 2006; 123 (4): 321-33.                          


Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1., Terada K, Kitayama A, Kanamoto T, Ueno N, Furukawa T., Dev Biol. March 15, 2006; 291 (2): 398-412.          


Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1., Terada K, Kitayama A, Kanamoto T, Ueno N, Furukawa T., Dev Biol. March 15, 2006; 291 (2): 398-412.          


Role of X-Delta-2 in the early neural development of Xenopus laevis., Peres JN, Durston AJ., Dev Dyn. March 1, 2006; 235 (3): 802-10.                                              

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