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XB--976057
Papers associated with cdc45
Results 1 - 50 of 88 results
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Novel role of DONSON in CMG helicase assembly during vertebrate DNA replication initiation., Hashimoto Y, Sadano K, Miyata N, Ito H, Tanaka H., EMBO J. July 17, 2023; e114131.  |
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The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase., Tarcan Z, Poovathumkadavil D, Skagia A, Gambus A., J Biol Chem. August 1, 2022; 298 (8): 102234.  |
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The HMCES DNA-protein cross-link functions as an intermediate in DNA interstrand cross-link repair., Semlow DR, MacKrell VA, Walter JC., Nat Struct Mol Biol. May 1, 2022; 29 (5): 451-462. |
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Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus., Ciardo D, Haccard O, Narassimprakash H, Cornu D, Guerrera IC, Goldar A, Marheineke K., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.  |
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Multistep mechanism of G-quadruplex resolution during DNA replication., Sato K, Martin-Pintado N, Post H, Altelaar M, Knipscheer P., Sci Adv. September 24, 2021; 7 (39): eabf8653. |
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The DNA replication fork suppresses CMG unloading from chromatin before termination., Low E, Chistol G, Zaher MS, Kochenova OV, Walter JC., Genes Dev. November 1, 2020; 34 (21-22): 1534-1545. |
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DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain., Kyono Y, Raj S, Sifuentes CJ, Buisine N, Sachs L, Denver RJ., Dev Biol. June 15, 2020; 462 (2): 180-196.  |
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Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Heintzman DR, Campos LV, Byl JAW, Osheroff N, Dewar JM., Cell Rep. October 8, 2019; 29 (2): 422-436.e5.  |
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Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity., Priego Moreno S, Jones RM, Poovathumkadavil D, Scaramuzza S, Gambus A., Life Sci Alliance. April 12, 2019; 2 (2):  |
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RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR., Lyu K, Kumagai A, Dunphy WG., Cell Cycle. April 1, 2019; 18 (8): 898-913.  |
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Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements., Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC., Mol Cell. March 7, 2019; 73 (5): 915-929.e6.  |
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TRAIP is a master regulator of DNA interstrand crosslink repair., Wu RA, Semlow DR, Kamimae-Lanning AN, Kochenova OV, Chistol G, Hodskinson MR, Amunugama R, Sparks JL, Wang M, Deng L, Mimoso CA, Low E, Patel KJ, Walter JC., Nature. March 1, 2019; 567 (7747): 267-272.  |
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Claspin - checkpoint adaptor and DNA replication factor., Smits VAJ, Cabrera E, Freire R, Gillespie DA., FEBS J. February 1, 2019; 286 (3): 441-455. |
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Mitotic entry drives replisome disassembly at stalled replication forks., Hashimoto Y, Tanaka H., Biochem Biophys Res Commun. November 17, 2018; 506 (1): 108-113.  |
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Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading., Amunugama R, Willcox S, Wu RA, Abdullah UB, El-Sagheer AH, Brown T, McHugh PJ, Griffith JD, Walter JC., Cell Rep. June 19, 2018; 23 (12): 3419-3428.  |
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The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism., Li H, O'Donnell ME., Bioessays. March 1, 2018; 40 (3): |
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Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei., Okada T, Okabe G, Tak YS, Mimura S, Takisawa H, Kubota Y., Genes Cells. February 1, 2018; 23 (2): 94-104. |
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MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication., Kumagai A, Dunphy WG., Mol Biol Cell. November 1, 2017; 28 (22): 2998-3012.  |
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An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7., Perez-Arnaiz P, Bruck I, Colbert MK, Kaplan DL., Nucleic Acids Res. July 7, 2017; 45 (12): 7261-7275.  |
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Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1., Alver RC, Chadha GS, Gillespie PJ, Blow JJ., Cell Rep. March 7, 2017; 18 (10): 2508-2520.  |
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p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair., Fullbright G, Rycenga HB, Gruber JD, Long DT., Mol Cell Biol. November 14, 2016; 36 (23): 2983-2994. |
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Xenopus Mcm10 is a CDK-substrate required for replication fork stability., Chadha GS, Gambus A, Gillespie PJ, Blow JJ., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.  |
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Structure of human Cdc45 and implications for CMG helicase function., Simon AC, Sannino V, Costanzo V, Pellegrini L., Nat Commun. May 18, 2016; 7 11638.  |
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Direct non transcriptional role of NF-Y in DNA replication., Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, Basile V, Schwob E, Mantovani R, Blow JJ, Imbriano C., Biochim Biophys Acta. April 1, 2016; 1863 (4): 673-85. |
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Studying essential DNA metabolism proteins in Xenopus egg extract., Sannino V, Kolinjivadi AM, Baldi G, Costanzo V., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 221-227. |
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The mechanism of DNA replication termination in vertebrates., Dewar JM, Budzowska M, Walter JC., Nature. September 17, 2015; 525 (7569): 345-50.  |
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DNA interstrand cross-link repair requires replication-fork convergence., Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC., Nat Struct Mol Biol. March 1, 2015; 22 (3): 242-7.  |
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Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication., Guo C, Kumagai A, Schlacher K, Shevchenko A, Shevchenko A, Dunphy WG., Mol Cell. February 5, 2015; 57 (3): 492-505. |
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RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts., Sanuki Y, Kubota Y, Kanemaki MT, Takahashi TS, Mimura S, Takisawa H., Cell Cycle. January 1, 2015; 14 (7): 1010-23. |
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Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation., Gao Y, Yao J, Poudel S, Romer E, Abu-Niaaj L, Leffak M., J Biol Chem. December 26, 2014; 289 (52): 35987-6000. |
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NCOA4 transcriptional coactivator inhibits activation of DNA replication origins., Bellelli R, Castellone MD, Guida T, Limongello R, Dathan NA, Merolla F, Cirafici AM, Affuso A, Masai H, Costanzo V, Grieco D, Fusco A, Santoro M, Carlomagno F., Mol Cell. July 3, 2014; 55 (1): 123-37. |
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Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1., Poh WT, Chadha GS, Gillespie PJ, Kaldis P, Blow JJ., Open Biol. January 8, 2014; 4 130138.  |
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Mta2 promotes Tipin-dependent maintenance of replication fork integrity., Errico A, Aze A, Costanzo V., Cell Cycle. January 1, 2014; 13 (13): 2120-8.  |
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Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts., Taylor EM, Bonsu NM, Price RJ, Lindsay HD., Nucleic Acids Res. September 1, 2013; 41 (16): 7725-37.  |
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DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts., Gaggioli V, Le Viet B, Germe T, Hyrien O., Nucleic Acids Res. August 1, 2013; 41 (15): 7313-31.  |
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Cdc45 is a critical effector of myc-dependent DNA replication stress., Srinivasan SV, Dominguez-Sola D, Wang LC, Hyrien O, Gautier J., Cell Rep. May 30, 2013; 3 (5): 1629-39. |
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The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks., Lee J, Dunphy WG., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.  |
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Evolutionary diversification of eukaryotic DNA replication machinery., Aves SJ, Liu Y, Richards TA., Subcell Biochem. January 1, 2012; 62 19-35. |
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RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks., Hashimoto Y, Puddu F, Costanzo V., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.  |
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Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication., Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., J Cell Biol. June 13, 2011; 193 (6): 995-1007.  |
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MCM2-7 form double hexamers at licensed origins in Xenopus egg extract., Gambus A, Khoudoli GA, Jones RC, Blow JJ., J Biol Chem. April 1, 2011; 286 (13): 11855-64.  |
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Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.  |
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GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.  |
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Replication origins and timing of temporal replication in budding yeast: how to solve the conundrum?, Barberis M, Spiesser TW, Klipp E., Curr Genomics. May 1, 2010; 11 (3): 199-211.  |
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The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation., Chowdhury A, Liu G, Kemp M, Chen X, Katrangi N, Myers S, Ghosh M, Yao J, Gao Y, Bubulya P, Leffak M., Mol Cell Biol. March 1, 2010; 30 (6): 1495-507. |
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Treslin collaborates with TopBP1 in triggering the initiation of DNA replication., Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell. February 5, 2010; 140 (3): 349-59.  |
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Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion., Errico A, Cosentino C, Rivera T, Losada A, Schwob E, Hunt T, Costanzo V., EMBO J. December 2, 2009; 28 (23): 3681-92.  |
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MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication., Xu X, Rochette PJ, Feyissa EA, Su TV, Liu Y., EMBO J. October 7, 2009; 28 (19): 3005-14. |
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The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication., Aparicio T, Guillou E, Coloma J, Montoya G, Méndez J., Nucleic Acids Res. April 1, 2009; 37 (7): 2087-95.  |
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Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.  |
