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Summary Expression Phenotypes Gene Literature (52) GO Terms (4) Nucleotides (77) Proteins (42) Interactants (128) Wiki
XB-GENEPAGE-950953

Papers associated with cnga1



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Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels., Flynn GE, Zagotta WN., Neuron. June 1, 2001; 30 (3): 689-98.

Rotational movement during cyclic nucleotide-gated channel opening., Johnson JP, Zagotta WN., Nature. August 30, 2001; 412 (6850): 917-21.

An intersubunit interaction regulates trafficking of rod cyclic nucleotide-gated channels and is disrupted in an inherited form of blindness., Trudeau MC, Zagotta WN., Neuron. April 11, 2002; 34 (2): 197-207.

Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels., Trudeau MC, Zagotta WN., Proc Natl Acad Sci U S A. June 11, 2002; 99 (12): 8424-9.          

Purification and cloning of toxins from elapid venoms that target cyclic nucleotide-gated ion channels., Yamazaki Y, Brown RL, Morita T., Biochemistry. September 24, 2002; 41 (38): 11331-7.

An endogenous RNA transcript antisense to CNG(alpha)1 cation channel mRNA., Cheng CH, Yew DT, Kwan HY, Zhou Q, Huang Y, Liu Y, Chan WY, Yao X., Mol Biol Cell. October 1, 2002; 13 (10): 3696-705.

Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit., Zheng J, Trudeau MC, Zagotta WN., Neuron. December 5, 2002; 36 (5): 891-6.

Dequalinium: a novel, high-affinity blocker of CNGA1 channels., Rosenbaum T, Islas LD, Carlson AE, Gordon SE., J Gen Physiol. January 1, 2003; 121 (1): 37-47.                        

Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites., Moss EG, Tang L., Dev Biol. June 15, 2003; 258 (2): 432-42.        

Subunit contributions to phosphorylation-dependent modulation of bovine rod cyclic nucleotide-gated channels., Molokanova E, Krajewski JL, Satpaev D, Luetje CW, Kramer RH., J Physiol. October 15, 2003; 552 (Pt 2): 345-56.

Tyrosine phosphorylation of rod cyclic nucleotide-gated channels switches off Ca2+/calmodulin inhibition., Krajewski JL, Luetje CW, Kramer RH., J Neurosci. November 5, 2003; 23 (31): 10100-6.

Distinct structural determinants of efficacy and sensitivity in the ligand-binding domain of cyclic nucleotide-gated channels., Young EC, Krougliak N., J Biol Chem. January 30, 2004; 279 (5): 3553-62.

State-dependent block of CNG channels by dequalinium., Rosenbaum T, Gordon-Shaag A, Islas LD, Cooper J, Munari M, Gordon SE., J Gen Physiol. March 1, 2004; 123 (3): 295-304.                  

All-trans-retinal is a closed-state inhibitor of rod cyclic nucleotide-gated ion channels., McCabe SL, Pelosi DM, Tetreault M, Miri A, Nguitragool W, Kovithvathanaphong P, Mahajan R, Zimmerman AL., J Gen Physiol. May 1, 2004; 123 (5): 521-31.                

Dynamics of Ca2+-calmodulin-dependent inhibition of rod cyclic nucleotide-gated channels measured by patch-clamp fluorometry., Trudeau MC, Zagotta WN., J Gen Physiol. September 1, 2004; 124 (3): 211-23.              

Effects of permeating ions and cGMP on gating and conductance of rod-type cyclic nucleotide-gated (CNGA1) channels., Kusch J, Nache V, Benndorf K., J Physiol. November 1, 2004; 560 (Pt 3): 605-16.

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB, Zagotta WN., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      

The carboxyl-terminal region of cyclic nucleotide-modulated channels is a gating ring, not a permeation path., Johnson JP, Zagotta WN., Proc Natl Acad Sci U S A. February 22, 2005; 102 (8): 2742-7.

Functional interactions between A' helices in the C-linker of open CNG channels., Hua L, Gordon SE., J Gen Physiol. March 1, 2005; 125 (3): 335-44.              

Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel., Qu W, Moorhouse AJ, Lewis TM, Pierce KD, Barry PH., Eur Biophys J. July 1, 2005; 34 (5): 442-53.

Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies., Strassmaier T, Uma R, Ghatpande AS, Bandyopadhyay T, Schaffer M, Witte J, McDougal PG, Brown RL, Karpen JW., J Med Chem. September 8, 2005; 48 (18): 5805-12.

Defining the retinoid binding site in the rod cyclic nucleotide-gated channel., Horrigan DM, Tetreault ML, Tsomaia N, Vasileiou C, Borhan B, Mierke DF, Crouch RK, Zimmerman AL., J Gen Physiol. November 1, 2005; 126 (5): 453-60.          

RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1., Hendriksen J, Fagotto F, van der Velde H, van Schie M, Noordermeer J, Fornerod M., J Cell Biol. December 5, 2005; 171 (5): 785-97.                  

Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate., Contreras JE, Holmgren M., J Gen Physiol. May 1, 2006; 127 (5): 481-94.                        

Gating of cyclic nucleotide-gated (CNGA1) channels by cGMP jumps and depolarizing voltage steps., Nache V, Kusch J, Hagen V, Benndorf K., Biophys J. May 1, 2006; 90 (9): 3146-54.

Locking CNGA1 channels in the open and closed state., Nair AV, Mazzolini M, Codega P, Giorgetti A, Torre V., Biophys J. May 15, 2006; 90 (10): 3599-607.

Short-range molecular rearrangements in ion channels detected by tryptophan quenching of bimane fluorescence., Islas LD, Zagotta WN., J Gen Physiol. September 1, 2006; 128 (3): 337-46.                  

C-terminal movement during gating in cyclic nucleotide-modulated channels., Craven KB, Olivier NB, Zagotta WN., J Biol Chem. May 23, 2008; 283 (21): 14728-38.

Cyclic GMP-gated CNG channels function in Sema3A-induced growth cone repulsion., Togashi K, von Schimmelmann MJ, Nishiyama M, Lim CS, Yoshida N, Yun B, Molday RS, Goshima Y, Hong K., Neuron. June 12, 2008; 58 (5): 694-707.

A comparison of electrophysiological properties of the CNGA1, CNGA1tandem and CNGA1cys-free channels., Mazzolini M, Nair AV, Torre V., Eur Biophys J. July 1, 2008; 37 (6): 947-59.

The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gating., Mazzolini M, Anselmi C, Torre V., J Gen Physiol. April 1, 2009; 133 (4): 375-86.            

Mutations reveal voltage gating of CNGA1 channels in saturating cGMP., Martínez-François JR, Xu Y, Xu Y, Lu Z., J Gen Physiol. August 1, 2009; 134 (2): 151-64.                      

Mad is required for wingless signaling in wing development and segment patterning in Drosophila., Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM., PLoS One. August 6, 2009; 4 (8): e6543.                    

Intrinsic versus extrinsic voltage sensitivity of blocker interaction with an ion channel pore., Martínez-François JR, Lu Z., J Gen Physiol. February 1, 2010; 135 (2): 149-67.                              

The Drosophila gene CheB42a is a novel modifier of Deg/ENaC channel function., Ben-Shahar Y, Lu B, Collier DM, Snyder PM, Schnizler M, Welsh MJ., PLoS One. February 2, 2010; 5 (2): e9395.              

Matrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels., Meighan PC, Meighan SE, Rich ED, Brown RL, Varnum MD., Channels (Austin). January 1, 2012; 6 (3): 181-96.                        

Restoration of proper trafficking to the cell surface for membrane proteins harboring cysteine mutations., Lopez-Rodriguez A, Holmgren M., PLoS One. January 1, 2012; 7 (10): e47693.        

A ring of threonines in the inner vestibule of the pore of CNGA1 channels constitutes a binding site for permeating ions., Marchesi A, Mazzolini M, Torre V., J Physiol. October 15, 2012; 590 (20): 5075-90.

Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides., Dai G, Peng C, Liu C, Varnum MD., J Gen Physiol. April 1, 2013; 141 (4): 413-30.                

Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels., Arcangeletti M, Marchesi A, Mazzolini M, Torre V., Physiol Rep. November 1, 2013; 1 (6): e00148.                        

Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating., Meighan SE, Meighan PC, Rich ED, Brown RL, Varnum MD., Biochemistry. November 19, 2013; 52 (46): 8352-62.

Submembrane assembly and renewal of rod photoreceptor cGMP-gated channel: insight into the actin-dependent process of outer segment morphogenesis., Nemet I, Tian G, Imanishi Y., J Neurosci. June 11, 2014; 34 (24): 8164-74.                  

Retrograde intraciliary trafficking of opsin during the maintenance of cone-shaped photoreceptor outer segments of Xenopus laevis., Tian G, Lodowski KH, Lee R, Imanishi Y., J Comp Neurol. November 1, 2014; 522 (16): 3577-3589.            

Ca-α1T, a fly T-type Ca2+ channel, negatively modulates sleep., Jeong K, Lee S, Seo H, Oh Y, Jang D, Choe J, Kim D, Lee JH, Jones WD., Sci Rep. January 12, 2015; 5 17893.            

Proton transfer unlocks inactivation in cyclic nucleotide-gated A1 channels., Marchesi A, Arcangeletti M, Mazzolini M, Torre V., J Physiol. February 15, 2015; 593 (4): 857-70.

Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy., Maity S, Mazzolini M, Arcangeletti M, Valbuena A, Fabris P, Lazzarino M, Torre V., Nat Commun. May 12, 2015; 6 7093.              

Localized JNK signaling regulates organ size during development., Willsey HR, Zheng X, Carlos Pastor-Pareja J, Willsey AJ, Beachy PA, Xu T., Elife. January 28, 2016; 5                       

Regulation of CNGA1 Channel Gating by Interactions with the Membrane., Aman TK, Gordon SE, Zagotta WN., J Biol Chem. May 6, 2016; 291 (19): 9939-47.

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes., Oswald F, Rodriguez P, Giaimo BD, Antonello ZA, Mira L, Mittler G, Thiel VN, Collins KJ, Tabaja N, Cizelsky W, Rothe M, Kühl SJ, Kühl SJ, Kühl M, Ferrante F, Hein K, Kovall RA, Dominguez M, Borggrefe T., Nucleic Acids Res. June 2, 2016; 44 (10): 4703-20.                              

Structural Heterogeneity of CNGA1 Channels Revealed by Electrophysiology and Single-Molecule Force Spectroscopy., Maity S, Marchesi A, Torre V, Mazzolini M., ACS Omega. December 13, 2016; 1 (6): 1205-1219.

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