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Summary Expression Phenotypes Gene Literature (641) GO Terms (12) Nucleotides (235) Proteins (78) Interactants (1940) Wiki
XB--483057

Papers associated with bmp4 (and wnt3a)



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From neural tube to spinal cord: The dynamic journey of the dorsal neuroepithelium., Ventriglia S, Kalcheim C., Dev Biol. July 1, 2024; 511 26-38.

R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  

ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation., Wang C, Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y, Qi X, Cai D, Mao B, Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H., EMBO Rep. February 1, 2024; 25 (2): 646-671.                                          

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH., Development. October 1, 2021; 148 (19):               

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK, Saint-Jeannet JP., Dev Biol. August 1, 2021; 476 200-208.            

Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs., Aztekin C, Hiscock TW, Gurdon J, Jullien J, Marioni J, Simons BD., Development. June 1, 2021; 148 (11):                                             

Modeling endoderm development and disease in Xenopus., Edwards NA, Zorn AM., Curr Top Dev Biol. January 1, 2021; 145 61-90.

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H, Lee H, Seidl C, Sun R, Glinka A, Niehrs C., Nat Commun. November 4, 2020; 11 (1): 5570.                                            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

PAWS1 controls Wnt signalling through association with casein kinase 1α., Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC, Sapkota GP., EMBO Rep. April 1, 2018; 19 (4):                             

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.          

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling., Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H., J Biol Chem. September 4, 2015; 290 (36): 21925-38.                  

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y., Dev Cell. June 22, 2015; 33 (6): 660-74.                                  

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y., Dev Cell. June 22, 2015; 33 (6): 660-74.                                  

Hematopoiesis: from start to immune reconstitution potential., Liang HC, Zúñiga-Pflücker JC., Stem Cell Res Ther. April 11, 2015; 6 52.        

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus., Matsukawa S, Miwata K, Asashima M, Michiue T., Dev Biol. March 1, 2015; 399 (1): 164-176.                    

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Direct regulation of siamois by VegT is required for axis formation in Xenopus embryo., Li HY, El Yakoubi W, Shi DL., Int J Dev Biol. January 1, 2015; 59 (10-12): 443-51.                          

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

Signaling and transcriptional regulation in neural crest specification and migration: lessons from xenopus embryos., Pegoraro C, Monsoro-Burq AH., Wiley Interdiscip Rev Dev Biol. January 1, 2013; 2 (2): 247-59.      

Current perspectives of the signaling pathways directing neural crest induction., Stuhlmiller TJ, García-Castro MI., Cell Mol Life Sci. November 1, 2012; 69 (22): 3715-37.          

Transient downregulation of Bmp signalling induces extra limbs in vertebrates., Christen B, Rodrigues AM, Monasterio MB, Roig CF, Izpisua Belmonte JC., Development. July 1, 2012; 139 (14): 2557-65.        

Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo., Tran HT, Sekkali B, Van Imschoot G, Janssens S, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.                                                

Long-term consequences of Sox9 depletion on inner ear development., Park BY, Saint-Jeannet JP., Dev Dyn. April 1, 2010; 239 (4): 1102-12.          

Long-term consequences of Sox9 depletion on inner ear development., Park BY, Saint-Jeannet JP., Dev Dyn. April 1, 2010; 239 (4): 1102-12.          

Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration., Lin G, Slack JM., Dev Biol. April 15, 2008; 316 (2): 323-35.              

Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration., Lin G, Slack JM., Dev Biol. April 15, 2008; 316 (2): 323-35.              

Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling., Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C., Development. December 1, 2007; 134 (23): 4255-63.      

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM., Cell. November 30, 2007; 131 (5): 980-93.      

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity., Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.              

Tcf- and Vent-binding sites regulate neural-specific geminin expression in the gastrula embryo., Taylor JJ, Wang T, Kroll KL., Dev Biol. January 15, 2006; 289 (2): 494-506.                

The zic1 gene is an activator of Wnt signaling., Merzdorf CS, Sive HL., Int J Dev Biol. January 1, 2006; 50 (7): 611-7.              

Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm., Sato T, Sasai N, Sasai Y., Development. May 1, 2005; 132 (10): 2355-63.          

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis., Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W., Dev Cell. October 1, 2004; 7 (4): 525-34.                          

Specification of the otic placode depends on Sox9 function in Xenopus., Saint-Germain N, Lee YH, Lee YH, Zhang Y, Zhang Y, Sargent TD, Saint-Jeannet JP., Development. April 1, 2004; 131 (8): 1755-63.              

Specification of the otic placode depends on Sox9 function in Xenopus., Saint-Germain N, Lee YH, Lee YH, Zhang Y, Zhang Y, Sargent TD, Saint-Jeannet JP., Development. April 1, 2004; 131 (8): 1755-63.              

The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning., Kazanskaya O, Glinka A, Niehrs C., Development. November 1, 2000; 127 (22): 4981-92.              

Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development., Baker JC, Beddington RS, Harland RM., Genes Dev. December 1, 1999; 13 (23): 3149-59.              

Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth., Beck CW, Slack JM., Mech Dev. March 1, 1998; 72 (1-2): 41-52.                                                                

Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth., Beck CW, Slack JM., Mech Dev. March 1, 1998; 72 (1-2): 41-52.                                                                

Ectodermal patterning in vertebrate embryos., Sasai Y, De Robertis EM., Dev Biol. February 1, 1997; 182 (1): 5-20.              

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