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Summary Expression Phenotypes Gene Literature (226) GO Terms (6) Nucleotides (305) Proteins (73) Interactants (445) Wiki
XB-GENEPAGE-921634

Papers associated with gnao1



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Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline., Jo SH, Youm JB, Lee CO, Lee CO, Earm YE, Ho WK., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects., Kreutner W, Hey JA, Chiu P, Barnett A., Arzneimittelforschung. May 1, 2000; 50 (5): 441-8.

Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation., Ulens C, Tytgat J., FEBS Lett. May 26, 2000; 474 (1): 111-5.

Altered gating of HERG potassium channels by cobalt and lanthanum., Sanchez-Chapula JA, Sanguinetti MC., Pflugers Arch. June 1, 2000; 440 (2): 264-74.

Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function., Brickman JM, Jones CM, Clements M, Smith JC, Beddington RS., Development. June 1, 2000; 127 (11): 2303-15.                    

Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating., Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P., Biophys J. July 1, 2000; 79 (1): 231-46.

Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin., Schönherr R, Löber K, Heinemann SH., EMBO J. July 3, 2000; 19 (13): 3263-71.

State-dependent barium block of wild-type and inactivation-deficient HERG channels in Xenopus oocytes., Weerapura M, Nattel S, Courtemanche M, Doern D, Ethier N, Hebert T., J Physiol. July 15, 2000; 526 Pt 2 265-78.

Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3., Silverman WR, Tang CY, Mock AF, Huh KB, Papazian DM., J Gen Physiol. November 1, 2000; 116 (5): 663-78.                  

Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes., Li BX, Yang BF, Zhou J, Xu CQ, Li YR., Acta Pharmacol Sin. February 1, 2001; 22 (2): 125-31.

Antiarrhythmic drug carvedilol inhibits HERG potassium channels., Karle CA, Kreye VA, Thomas D, Röckl K, Kathöfer S, Zhang W, Kiehn J., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.

Molecular cloning and expression of cERG, the ether à go-go-related gene from canine myocardium., Zehelein J, Zhang W, Koenen M, Graf M, Heinemann SH, Katus HA., Pflugers Arch. May 1, 2001; 442 (2): 188-91.

High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872., Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.

Functional characterization of the C-terminus of the human ether-à-go-go-related gene K(+) channel (HERG)., Aydar E, Palmer C., J Physiol. July 1, 2001; 534 (Pt 1): 1-14.

The S4-S5 linker couples voltage sensing and activation of pacemaker channels., Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC., Proc Natl Acad Sci U S A. September 25, 2001; 98 (20): 11277-82.

Developmental biology. Organs await blood vessels'' go signal., Seydel C., Science. September 28, 2001; 293 (5539): 2365.

Identification of a nonmammalian Golf subtype: functional role in olfactory signaling of airborne odorants in Xenopus laevis., Mezler M, Fleischer J, Conzelmann S, Korchi A, Widmayer P, Breer H, Boekhoff I., J Comp Neurol. October 29, 2001; 439 (4): 400-10.      

Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels., Ficker E, Jarolimek W, Brown AM., Mol Pharmacol. December 1, 2001; 60 (6): 1343-8.

Inhibition of cardiac potassium currents by pentobarbital., Bachmann A, Mueller S, Kopp K, Brueggemann A, Suessbrich H, Gerlach U, Busch AE., Naunyn Schmiedebergs Arch Pharmacol. January 1, 2002; 365 (1): 29-37.

The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels., Thomas D, Gut B, Wendt-Nordahl G, Kiehn J., J Pharmacol Exp Ther. February 1, 2002; 300 (2): 543-8.

Interactions between S4-S5 linker and S6 transmembrane domain modulate gating of HERG K+ channels., Tristani-Firouzi M, Chen J, Sanguinetti MC., J Biol Chem. May 24, 2002; 277 (21): 18994-9000.

Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block., Sánchez-Chapula JA, Navarro-Polanco RA, Culberson C, Chen J, Sanguinetti MC., J Biol Chem. June 28, 2002; 277 (26): 23587-95.

Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels., Park JB, Choe H, Lee YK, Ha KC, Rhee KS, Ko JK, Joo CU, Chae SW, Kwak YG., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.

Calcium/calmodulin-dependent protein kinase II phosphorylates and regulates the Drosophila eag potassium channel., Wang Z, Wilson GF, Griffith LC., J Biol Chem. July 5, 2002; 277 (27): 24022-9.

Factors affecting oogenesis in the South African clawed frog (Xenopus laevis)., Green SL., Comp Med. August 1, 2002; 52 (4): 307-12.

Kinetics of tethering quaternary ammonium compounds to K(+) channels., Blaustein RO., J Gen Physiol. August 1, 2002; 120 (2): 203-16.                    

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current., Angelo K, Jespersen T, Grunnet M, Nielsen MS, Klaerke DA, Olesen SP., Biophys J. October 1, 2002; 83 (4): 1997-2006.

Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene., Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA., J Biol Chem. December 6, 2002; 277 (49): 47779-85.

Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region., Shoeb F, Malykhina AP, Akbarali HI., J Biol Chem. January 24, 2003; 278 (4): 2503-14.

Structural basis of two-stage voltage-dependent activation in K+ channels., Silverman WR, Roux B, Papazian DM., Proc Natl Acad Sci U S A. March 4, 2003; 100 (5): 2935-40.

Molecular characterization, functional expression, and developmental profile of an ether à-go-go K+ channel in the tobacco hornworm Manduca sexta., Keyser MR, Anson BD, Titus SA, Ganetzky B, Witten JL., J Neurobiol. April 1, 2003; 55 (1): 73-85.

Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain., Sănchez-Chapula JA, Ferrer T, Navarro-Polanco RA, Sanguinetti MC., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.

BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1., Zhang M, Korolkova YV, Liu J, Jiang M, Grishin EV, Tseng GN., Biophys J. May 1, 2003; 84 (5): 3022-36.

Gating currents associated with intramembrane charge displacement in HERG potassium channels., Piper DR, Varghese A, Sanguinetti MC, Tristani-Firouzi M., Proc Natl Acad Sci U S A. September 2, 2003; 100 (18): 10534-9.

GoSurfer: a graphical interactive tool for comparative analysis of large gene sets in Gene Ontology space., Zhong S, Storch KF, Lipan O, Kao MC, Weitz CJ, Wong WH., Appl Bioinformatics. January 1, 2004; 3 (4): 261-4.

G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes., Itzhaki Van-Ham I, Peleg S, Dascal N, Shapira H, Oron Y., FEBS Lett. April 23, 2004; 564 (1-2): 157-60.

Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels., Dong DL, Li Z, Wang HZ, Du ZM, Song WH, Yang BF., Basic Clin Pharmacol Toxicol. May 1, 2004; 94 (5): 209-12.

Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D, Wimmer AB, Wu K, Hammerling BC, Ficker EK, Kuryshev YA, Kiehn J, Katus HA, Schoels W, Karle CA., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.

Comparison of kinetic properties of quinidine and dofetilide block of HERG channels., Tsujimae K, Suzuki S, Yamada M, Kurachi Y., Eur J Pharmacol. June 16, 2004; 493 (1-3): 29-40.

Response to lysophosphatidic acid in Xenopus oocytes and its rapid desensitization: the role of Gq and Go G-protein families., Van-Ham II, Lupu-Meiri M, Tayer M, Shapira H, Oron Y., J Cell Physiol. July 1, 2004; 200 (1): 125-33.

Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel., Subbiah RN, Clarke CE, Smith DJ, Zhao J, Campbell TJ, Vandenberg JI., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.

Intracellular actin-based transport: how far you go depends on how often you switch., Snider J, Lin F, Zahedi N, Rodionov V, Yu CC, Gross SP., Proc Natl Acad Sci U S A. September 7, 2004; 101 (36): 13204-9.

Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel., Silverman WR, Bannister JP, Papazian DM., Biophys J. November 1, 2004; 87 (5): 3110-21.

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB, Zagotta WN., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      

Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA, Navarro-Polanco RA, Sanguinetti MC., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.

Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D, Wu K, Wimmer AB, Zitron E, Hammerling BC, Kathöfer S, Lueck S, Bloehs R, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.

A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C, Cvetanovic I, Ke X, Ranade V, Somberg J., Am J Ther. January 1, 2005; 12 (4): 328-36.

Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain., Csanády L, Chan KW, Nairn AC, Gadsby DC., J Gen Physiol. January 1, 2005; 125 (1): 43-55.              

Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels., Dupuis DS, Klaerke DA, Olesen SP., Basic Clin Pharmacol Toxicol. February 1, 2005; 96 (2): 123-30.

An atlas of differential gene expression during early Xenopus embryogenesis., Pollet N, Muncke N, Verbeek B, Li Y, Fenger U, Delius H, Niehrs C., Mech Dev. March 1, 2005; 122 (3): 365-439.                                                                                                                                                        

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