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Summary Expression Phenotypes Gene Literature (138) GO Terms (18) Nucleotides (120) Proteins (61) Interactants (770) Wiki
XB-GENEPAGE-5966550

Papers associated with thra



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Basic transcription element binding protein is a thyroid hormone-regulated transcription factor expressed during metamorphosis in Xenopus laevis., Hoopfer ED, Huang L, Denver RJ., Dev Growth Differ. October 1, 2002; 44 (5): 365-81.                


Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis., Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.


Ontogenic emergence and localization of larval skin antigen molecule recognized by adult T cells of Xenopus laevis: Regulation by thyroid hormone during metamorphosis., Watanabe M, Ohshima M, Morohashi M, Maéno M, Izutsu Y., Dev Growth Differ. February 1, 2003; 45 (1): 77-84.        


Expression of type II iodothyronine deiodinase marks the time that a tissue responds to thyroid hormone-induced metamorphosis in Xenopus laevis., Cai L, Brown DD., Dev Biol. February 1, 2004; 266 (1): 87-95.                


Molecular cloning and developmental expression patterns of thyroid hormone receptors and T3 target genes in the turbot (Scophtalmus maximus) during post-embryonic development., Marchand O, Duffraisse M, Triqueneaux G, Safi R, Laudet V., Gen Comp Endocrinol. February 1, 2004; 135 (3): 345-57.


Early expression of thyroid hormone receptor beta and retinoid X receptor gamma in the Xenopus embryo., Cossette SM, Drysdale TA., Differentiation. June 1, 2004; 72 (5): 239-49.            


Induction of larval tissue resorption in Xenopus laevis tadpoles by the thyroid hormone receptor agonist GC-1., Furlow JD, Yang HY, Hsu M, Lim W, Ermio DJ, Chiellini G, Scanlan TS., J Biol Chem. June 18, 2004; 279 (25): 26555-62.


Tissue- and gene-specific recruitment of steroid receptor coactivator-3 by thyroid hormone receptor during development., Paul BD, Buchholz DR, Fu L, Shi YB, Shi YB., J Biol Chem. July 22, 2005; 280 (29): 27165-72.


A causative role of stromelysin-3 in extracellular matrix remodeling and epithelial apoptosis during intestinal metamorphosis in Xenopus laevis., Fu L, Ishizuya-Oka A, Buchholz DR, Amano T, Matsuda H, Shi YB, Shi YB., J Biol Chem. July 29, 2005; 280 (30): 27856-65.


Gene-specific changes in promoter occupancy by thyroid hormone receptor during frog metamorphosis. Implications for developmental gene regulation., Buchholz DR, Paul BD, Shi YB., J Biol Chem. December 16, 2005; 280 (50): 41222-8.


Thyroid hormone receptor expression in the obligatory paedomorphic salamander Necturus maculosus., Vlaeminck-Guillem V, Safi R, Guillem P, Leteurtre E, Duterque-Coquillaud M, Laudet V., Int J Dev Biol. January 1, 2006; 50 (6): 553-60.


Molecular and developmental analyses of thyroid hormone receptor function in Xenopus laevis, the African clawed frog., Buchholz DR, Paul BD, Fu L, Shi YB, Shi YB., Gen Comp Endocrinol. January 1, 2006; 145 (1): 1-19.


Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors., Zhang F, Degitz SJ, Holcombe GW, Kosian PA, Tietge J, Veldhoen N, Helbing CC., Aquat Toxicol. January 5, 2006; 76 (1): 24-36.


Amphibian metamorphosis as a model for the developmental actions of thyroid hormone., Tata JR., Mol Cell Endocrinol. February 26, 2006; 246 (1-2): 10-20.


Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles., Opitz R, Hartmann S, Blank T, Braunbeck T, Lutz I, Kloas W., Toxicol Sci. April 1, 2006; 90 (2): 337-48.


Analysis of thyroid hormone receptor betaA mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action., Opitz R, Lutz I, Nguyen NH, Scanlan TS, Kloas W., Toxicol Appl Pharmacol. April 1, 2006; 212 (1): 1-13.


Polychlorinated biphenyl exposure delays metamorphosis and alters thyroid hormone system gene expression in developing Xenopus laevis., Lehigh Shirey EA, Jelaso Langerveld A, Mihalko D, Ide CF., Environ Res. October 1, 2006; 102 (2): 205-14.


Design and characterization of a thyroid hormone receptor alpha (TRalpha)-specific agonist., Ocasio CA, Scanlan TS., ACS Chem Biol. October 24, 2006; 1 (9): 585-93.


Small-molecule triggers of tadpole metamorphosis., Peterson BR., ACS Chem Biol. October 24, 2006; 1 (9): 559-61.


Effects of bisphenol A on thyroid hormone-dependent up-regulation of thyroid hormone receptor alpha and beta and down-regulation of retinoid X receptor gamma in Xenopus tail culture., Iwamuro S, Yamada M, Kato M, Kikuyama S., Life Sci. November 2, 2006; 79 (23): 2165-71.


The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development., Veldhoen N, Skirrow RC, Osachoff H, Wigmore H, Clapson DJ, Gunderson MP, Van Aggelen G, Helbing CC., Aquat Toxicol. December 1, 2006; 80 (3): 217-27.


Development of biomarkers of endocrine disrupting activity in emerging amphibian model, Silurana (Xenopus) tropicalis., Takase M, Mitsui N, Oka T, Tooi O, Santo N, Pickford DB, Iguchi T., Environ Sci. January 1, 2007; 14 (6): 285-96.


Expression of matrix metalloproteinase genes in regressing or remodeling organs during amphibian metamorphosis., Fujimoto K, Nakajima K, Yaoita Y., Dev Growth Differ. February 1, 2007; 49 (2): 131-43.


Amphibian metamorphosis., Brown DD, Cai L., Dev Biol. June 1, 2007; 306 (1): 20-33.          


Characterization of thyroid hormone receptor alpha (TRalpha)-specific analogs with varying inner- and outer-ring substituents., Ocasio CA, Scanlan TS., Bioorg Med Chem. January 15, 2008; 16 (2): 762-70.


Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis., Davey JC, Nomikos AP, Wungjiranirun M, Sherman JR, Ingram L, Batki C, Lariviere JP, Hamilton JW., Environ Health Perspect. February 1, 2008; 116 (2): 165-72.                


Multiple ING1 and ING2 genes in Xenopus laevis and evidence for differential association of thyroid hormone receptors and ING proteins to their promoters., Wagner MJ, Helbing CC., Biochim Biophys Acta. March 1, 2008; 1779 (3): 152-63.


Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis., Denver RJ, Hu F, Scanlan TS, Furlow JD., Dev Biol. February 1, 2009; 326 (1): 155-68.                


Molecular features of thyroid hormone-regulated skin remodeling in Xenopus laevis during metamorphosis., Suzuki K, Machiyama F, Nishino S, Watanabe Y, Kashiwagi K, Kashiwagi A, Yoshizato K., Dev Growth Differ. May 1, 2009; 51 (4): 411-27.                


Expression and T3 regulation of thyroid hormone- and sex steroid-related genes during Silurana (Xenopus) tropicalis early development., Duarte-Guterman P, Langlois VS, Pauli BD, Trudeau VL., Gen Comp Endocrinol. April 1, 2010; 166 (2): 428-35.          


Regulation of thyroid hormone-, oestrogen- and androgen-related genes by triiodothyronine in the brain of Silurana tropicalis., Duarte-Guterman P, Trudeau VL., J Neuroendocrinol. September 1, 2010; 22 (9): 1023-31.        


Amphibian organ remodeling during metamorphosis: insight into thyroid hormone-induced apoptosis., Ishizuya-Oka A., Dev Growth Differ. February 1, 2011; 53 (2): 202-12.


Triclosan and thyroid-mediated metamorphosis in anurans: differentiating growth effects from thyroid-driven metamorphosis in Xenopus laevis., Fort DJ, Mathis MB, Hanson W, Fort CE, Navarro LT, Peter R, Büche C, Unger S, Pawlowski S, Plautz JR., Toxicol Sci. June 1, 2011; 121 (2): 292-302.


Developmental profiles and thyroid hormone regulation of brain transcripts in frogs: a species comparison with emphasis on Physalaemus pustulosus., Duarte-Guterman P, Ryan MJ, Hogan NS, Trudeau VL., Brain Behav Evol. January 1, 2012; 79 (2): 98-112.


Characterization of a novel Xenopus tropicalis cell line as a model for in vitro studies., Sinzelle L, Thuret R, Hwang HY, Herszberg B, Paillard E, Bronchain OJ, Stemple DL, Dhorne-Pollet S, Pollet N., Genesis. March 1, 2012; 50 (3): 316-24.          


Translational regulation by the 5'-UTR of thyroid hormone receptor α mRNA., Okada M, Nakajima K, Yaoita Y., J Biochem. May 1, 2012; 151 (5): 519-31.


Regulation of thyroid hormone sensitivity by differential expression of the thyroid hormone receptor during Xenopus metamorphosis., Nakajima K, Fujimoto K, Yaoita Y., Genes Cells. August 1, 2012; 17 (8): 645-59.                


Thyroid hormone signaling in the Xenopus laevis embryo is functional and susceptible to endocrine disruption., Fini JB, Le Mével S, Palmier K, Darras VM, Punzon I, Richardson SJ, Clerget-Froidevaux MS, Demeneix BA., Endocrinology. October 1, 2012; 153 (10): 5068-81.


Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene., Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA., PLoS Genet. January 1, 2013; 9 (1): e1003188.                                                                


Enabling comparative gene expression studies of thyroid hormone action through the development of a flexible real-time quantitative PCR assay for use across multiple anuran indicator and sentinel species., Veldhoen N, Propper CR, Helbing CC., Aquat Toxicol. March 1, 2014; 148 162-73.


Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis., Choi J, Suzuki KT, Sakuma T, Shewade L, Yamamoto T, Buchholz DR., Endocrinology. February 1, 2015; 156 (2): 735-44.            


Chronic sublethal exposure to silver nanoparticles disrupts thyroid hormone signaling during Xenopus laevis metamorphosis., Carew AC, Hoque ME, Metcalfe CD, Peyrot C, Wilkinson KJ, Helbing CC., Aquat Toxicol. February 1, 2015; 159 99-108.


Apoptosis and differentiation of Xenopus tail-derived myoblasts by thyroid hormone., Tamura K, Takayama S, Ishii T, Mawaribuchi S, Takamatsu N, Ito M., J Mol Endocrinol. June 1, 2015; 54 (3): 185-92.


More similar than you think: Frog metamorphosis as a model of human perinatal endocrinology., Buchholz DR., Dev Biol. December 15, 2015; 408 (2): 188-95.        


Regulation of growth rate and developmental timing by Xenopus thyroid hormone receptor α., Wen L, Shi YB., Dev Growth Differ. January 1, 2016; 58 (1): 106-15.          


Life cycle exposure of the frog Silurana tropicalis to arsenate: Steroid- and thyroid hormone-related genes are differently altered throughout development., Gibson LA, Koch I, Reimer KJ, Cullen WR, Langlois VS., Gen Comp Endocrinol. August 1, 2016; 234 133-41.        


Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis., Hasebe T, Fujimoto K, Kajita M, Ishizuya-Oka A., Cell Tissue Res. August 1, 2016; 365 (2): 309-18.


A simple and efficient method to visualize and quantify the efficiency of chromosomal mutations from genome editing., Fu L, Wen L, Luu N, Shi YB, Shi YB., Sci Rep. October 17, 2016; 6 35488.                                


Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.                  


Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos., Fini JB, Mughal BB, Le Mével S, Leemans M, Lettmann M, Spirhanzlova P, Affaticati P, Jenett A, Demeneix BA., Sci Rep. March 7, 2017; 7 43786.        

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